-
1
-
-
84883397614
-
Signaling through dynamic linkers as revealed by PKA
-
COI: 1:CAS:528:DC%2BC3sXhsVCgtrnJ, PID: 23946424
-
Akimoto M, Selvaratnam R, McNicholl ET, Verma G, Taylor SS, Melacini G (2013) Signaling through dynamic linkers as revealed by PKA. Proc Natl Acad Sci USA 110(35):14231–14236
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.35
, pp. 14231-14236
-
-
Akimoto, M.1
Selvaratnam, R.2
McNicholl, E.T.3
Verma, G.4
Taylor, S.S.5
Melacini, G.6
-
2
-
-
0036293582
-
The essential role of RI alpha in the maintenance of regulated PKA activity
-
COI: 1:CAS:528:DC%2BD38XlvVSqs7c%3D, PID: 12119269
-
Amieux PS, McKnight GS (2002) The essential role of RI alpha in the maintenance of regulated PKA activity. Ann N Y Acad Sci 968:75–95
-
(2002)
Ann N Y Acad Sci
, vol.968
, pp. 75-95
-
-
Amieux, P.S.1
McKnight, G.S.2
-
3
-
-
84921326187
-
Molecular features of product release for the PKA catalytic cycle
-
Bastidas AC, Wu J, Taylor SS (2015) Molecular features of product release for the PKA catalytic cycle. Biochemistry 54:2–10
-
(2015)
Biochemistry
, vol.54
, pp. 2-10
-
-
Bastidas, A.C.1
Wu, J.2
Taylor, S.S.3
-
4
-
-
11844254469
-
The cAMP binding domain: an ancient signaling module
-
COI: 1:CAS:528:DC%2BD2MXmtlaqtA%3D%3D, PID: 15618393
-
Berman HM, Ten Eyck LF, Goodsell DS, Haste NM, Kornev A, Taylor SS (2005) The cAMP binding domain: an ancient signaling module. Proc Natl Acad Sci USA 102(1):45–50
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.1
, pp. 45-50
-
-
Berman, H.M.1
Ten Eyck, L.F.2
Goodsell, D.S.3
Haste, N.M.4
Kornev, A.5
Taylor, S.S.6
-
5
-
-
84908192391
-
Using Markov state models to develop a mechanistic understanding of protein kinase A regulatory subunit RIalpha activation in response to cAMP binding
-
COI: 1:CAS:528:DC%2BC2cXhvVSmtLvJ, PID: 25202018
-
Boras BW, Kornev A, Taylor SS, McCulloch AD (2014) Using Markov state models to develop a mechanistic understanding of protein kinase A regulatory subunit RIalpha activation in response to cAMP binding. J Biol Chem 289(43):30040–30051
-
(2014)
J Biol Chem
, vol.289
, Issue.43
, pp. 30040-30051
-
-
Boras, B.W.1
Kornev, A.2
Taylor, S.S.3
McCulloch, A.D.4
-
6
-
-
0029021176
-
Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase
-
COI: 1:CAS:528:DyaK2MXotVGqsb8%3D, PID: 7568030
-
Brandon EP, Zhuo M, Huang YY, Qi M, Gerhold KA, Burton KA, Kandel ER, McKnight GS, Idzerda RL (1995) Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase. Proc Natl Acad Sci USA 92(19):8851–8855
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, Issue.19
, pp. 8851-8855
-
-
Brandon, E.P.1
Zhuo, M.2
Huang, Y.Y.3
Qi, M.4
Gerhold, K.A.5
Burton, K.A.6
Kandel, E.R.7
McKnight, G.S.8
Idzerda, R.L.9
-
7
-
-
0030769381
-
PKA isoforms, neural pathways, and behaviour: making the connection
-
COI: 1:CAS:528:DyaK2sXkslWksr0%3D, PID: 9232801
-
Brandon EP, Idzerda RL, McKnight GS (1997) PKA isoforms, neural pathways, and behaviour: making the connection. Curr Opin Neurobiol 7(3):397–403
-
(1997)
Curr Opin Neurobiol
, vol.7
, Issue.3
, pp. 397-403
-
-
Brandon, E.P.1
Idzerda, R.L.2
McKnight, G.S.3
-
8
-
-
0015135521
-
Interaction of the subunits of adenosine 3′:5′-cyclic monophosphate-dependent protein kinase of muscle
-
COI: 1:CAS:528:DyaE38Xls1Snsw%3D%3D, PID: 4332811
-
Brostrom CO, Corbin JD, King CA, Krebs EG (1971) Interaction of the subunits of adenosine 3′:5′-cyclic monophosphate-dependent protein kinase of muscle. Proc Natl Acad Sci USA 68(10):2444–2447
-
(1971)
Proc Natl Acad Sci USA
, vol.68
, Issue.10
, pp. 2444-2447
-
-
Brostrom, C.O.1
Corbin, J.D.2
King, C.A.3
Krebs, E.G.4
-
9
-
-
0029737861
-
Genetically lean mice result from targeted disruption of the RII beta subunit of protein kinase A
-
COI: 1:CAS:528:DyaK28XltVWqs7s%3D, PID: 8757131
-
Cummings DE, Brandon EP, Planas JV, Motamed K, Idzerda RL, McKnight GS (1996) Genetically lean mice result from targeted disruption of the RII beta subunit of protein kinase A. Nature 382(6592):622–626
-
(1996)
Nature
, vol.382
, Issue.6592
, pp. 622-626
-
-
Cummings, D.E.1
Brandon, E.P.2
Planas, J.V.3
Motamed, K.4
Idzerda, R.L.5
McKnight, G.S.6
-
10
-
-
33745685964
-
Mapping allostery through equilibrium perturbation NMR spectroscopy
-
COI: 1:CAS:528:DC%2BD28XlvFens74%3D, PID: 16802799
-
Das R, Abu-Abed M, Melacini G (2006) Mapping allostery through equilibrium perturbation NMR spectroscopy. J Am Chem Soc 128(26):8406–8407
-
(2006)
J Am Chem Soc
, vol.128
, Issue.26
, pp. 8406-8407
-
-
Das, R.1
Abu-Abed, M.2
Melacini, G.3
-
11
-
-
0035148589
-
Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase: crystal structure of the type II beta regulatory subunit
-
COI: 1:CAS:528:DC%2BD3MXptFSktw%3D%3D, PID: 11342137
-
Diller TC, Madhusudan, Xuong NH, Taylor SS (2001) Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase: crystal structure of the type II beta regulatory subunit. Structure 9(1):73–82
-
(2001)
Structure
, vol.9
, Issue.1
, pp. 73-82
-
-
Diller, T.C.1
Madhusudan2
Xuong, N.H.3
Taylor, S.S.4
-
12
-
-
0019139770
-
Identification of two subclasses of type II cAMP-dependent protein kinases. Neural-specific and non-neural protein kinases
-
COI: 1:CAS:528:DyaL3cXlvVWksbg%3D, PID: 7410357
-
Erlichman J, Sarkar D, Fleischer N, Rubin CS (1980) Identification of two subclasses of type II cAMP-dependent protein kinases. Neural-specific and non-neural protein kinases. J Biol Chem 255(17):8179–8184
-
(1980)
J Biol Chem
, vol.255
, Issue.17
, pp. 8179-8184
-
-
Erlichman, J.1
Sarkar, D.2
Fleischer, N.3
Rubin, C.S.4
-
13
-
-
0032848914
-
Cyclic nucleotide-dependent protein kinases: intracellular receptors for cAMP and cGMP action
-
COI: 1:CAS:528:DyaK1MXmt1Olt7g%3D, PID: 10486703
-
Francis SH, Corbin JD (1999) Cyclic nucleotide-dependent protein kinases: intracellular receptors for cAMP and cGMP action. Crit Rev Clin Lab Sci 36(4):275–328
-
(1999)
Crit Rev Clin Lab Sci
, vol.36
, Issue.4
, pp. 275-328
-
-
Francis, S.H.1
Corbin, J.D.2
-
14
-
-
0014941286
-
A cyclic-3′,5′-adenosine monophosphate dependent protein kinase from the adrenal cortex: comparison with a cyclic AMP binding protein
-
COI: 1:CAS:528:DyaE3cXksVajsbk%3D, PID: 4316205
-
Gill GN, Garren LD (1970) A cyclic-3′,5′-adenosine monophosphate dependent protein kinase from the adrenal cortex: comparison with a cyclic AMP binding protein. Biochem Biophys Res Commun 39(3):335–343
-
(1970)
Biochem Biophys Res Commun
, vol.39
, Issue.3
, pp. 335-343
-
-
Gill, G.N.1
Garren, L.D.2
-
15
-
-
1842508814
-
C subunits binding to the protein kinase A RI alpha dimer induce a large conformational change
-
COI: 1:CAS:528:DC%2BD2cXjsVKmtLs%3D, PID: 14985329
-
Heller WT, Vigil D, Brown S, Blumenthal DK, Taylor SS, Trewhella J (2004) C subunits binding to the protein kinase A RI alpha dimer induce a large conformational change. J Biol Chem 279(18):19084–19090
-
(2004)
J Biol Chem
, vol.279
, Issue.18
, pp. 19084-19090
-
-
Heller, W.T.1
Vigil, D.2
Brown, S.3
Blumenthal, D.K.4
Taylor, S.S.5
Trewhella, J.6
-
16
-
-
0033545973
-
Dissection of the nucleotide and metal-phosphate binding sites in cAMP-dependent protein kinase
-
COI: 1:CAS:528:DyaK1MXisVaqtrk%3D, PID: 10320366
-
Herberg FW, Doyle ML, Cox S, Taylor SS (1999) Dissection of the nucleotide and metal-phosphate binding sites in cAMP-dependent protein kinase. Biochemistry 38(19):6352–6360
-
(1999)
Biochemistry
, vol.38
, Issue.19
, pp. 6352-6360
-
-
Herberg, F.W.1
Doyle, M.L.2
Cox, S.3
Taylor, S.S.4
-
17
-
-
0016772776
-
Comparison of adenosine 3′:5′-monophosphate-dependent protein kinases from rabbit skeletal and bovine heart muscle
-
COI: 1:CAS:528:DyaE2MXlvV2lurc%3D, PID: 170270
-
Hofmann F, Beavo JA, Bechtel PJ, Krebs EG (1975) Comparison of adenosine 3′:5′-monophosphate-dependent protein kinases from rabbit skeletal and bovine heart muscle. J Biol Chem 250(19):7795–7801
-
(1975)
J Biol Chem
, vol.250
, Issue.19
, pp. 7795-7801
-
-
Hofmann, F.1
Beavo, J.A.2
Bechtel, P.J.3
Krebs, E.G.4
-
18
-
-
77950427180
-
Mutations and polymorphisms in the gene encoding regulatory subunit type 1-alpha of protein kinase A (PRKAR1A): an update
-
COI: 1:CAS:528:DC%2BC3cXlslGhtL8%3D, PID: 20358582
-
Horvath A, Bertherat J, Groussin L, Guillaud-Bataille M, Tsang K, Cazabat L, Libe R, Remmers E, Rene-Corail F, Faucz FR, Clauser E, Calender A, Bertagna X, Carney JA, Stratakis CA (2010) Mutations and polymorphisms in the gene encoding regulatory subunit type 1-alpha of protein kinase A (PRKAR1A): an update. Hum Mutat 31(4):369–379
-
(2010)
Hum Mutat
, vol.31
, Issue.4
, pp. 369-379
-
-
Horvath, A.1
Bertherat, J.2
Groussin, L.3
Guillaud-Bataille, M.4
Tsang, K.5
Cazabat, L.6
Libe, R.7
Remmers, E.8
Rene-Corail, F.9
Faucz, F.R.10
Clauser, E.11
Calender, A.12
Bertagna, X.13
Carney, J.A.14
Stratakis, C.A.15
-
19
-
-
13344279399
-
A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning
-
COI: 1:CAS:528:DyaK28XhsVOnuw%3D%3D, PID: 8548807
-
Huang YY, Kandel ER, Varshavsky L, Brandon EP, Qi M, Idzerda RL, McKnight GS, Bourtchouladze R (1995) A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning. Cell 83(7):1211–1222
-
(1995)
Cell
, vol.83
, Issue.7
, pp. 1211-1222
-
-
Huang, Y.Y.1
Kandel, E.R.2
Varshavsky, L.3
Brandon, E.P.4
Qi, M.5
Idzerda, R.L.6
McKnight, G.S.7
Bourtchouladze, R.8
-
20
-
-
84864501436
-
Localization and quaternary structure of the PKA RIbeta holoenzyme
-
COI: 1:CAS:528:DC%2BC38XhtleqsrnF, PID: 22797896
-
Ilouz R, Bubis J, Wu J, Yim YY, Deal MS, Kornev AP, Ma Y, Blumenthal DK, Taylor SS (2012) Localization and quaternary structure of the PKA RIbeta holoenzyme. Proc Natl Acad Sci USA 109(31):12443–12448
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.31
, pp. 12443-12448
-
-
Ilouz, R.1
Bubis, J.2
Wu, J.3
Yim, Y.Y.4
Deal, M.S.5
Kornev, A.P.6
Ma, Y.7
Blumenthal, D.K.8
Taylor, S.S.9
-
21
-
-
33846590132
-
The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module
-
COI: 1:CAS:528:DC%2BD2sXht12jtbw%3D, PID: 17227859
-
Kannan N, Haste N, Taylor SS, Neuwald AF (2007a) The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module. Proc Natl Acad Sci USA 104(4):1272–1277
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.4
, pp. 1272-1277
-
-
Kannan, N.1
Haste, N.2
Taylor, S.S.3
Neuwald, A.F.4
-
22
-
-
33947226782
-
Structural and functional diversity of the microbial kinome
-
PID: 17355172
-
Kannan N, Taylor SS, Zhai Y, Venter JC, Manning G (2007b) Structural and functional diversity of the microbial kinome. PLoS Biol 5(3):e17
-
(2007)
PLoS Biol
, vol.5
, Issue.3
, pp. 17
-
-
Kannan, N.1
Taylor, S.S.2
Zhai, Y.3
Venter, J.C.4
Manning, G.5
-
23
-
-
36949091243
-
Structure of myoglobin: a three-dimensional Fourier synthesis at 2 A. resolution
-
COI: 1:CAS:528:DyaF3cXotVyntw%3D%3D, PID: 18990802
-
Kendrew JC, Dickerson RE, Strandberg BE, Hart RG, Davies DR, Phillips DC, Shore VC (1960) Structure of myoglobin: a three-dimensional Fourier synthesis at 2 A. resolution. Nature 185(4711):422–427
-
(1960)
Nature
, vol.185
, Issue.4711
, pp. 422-427
-
-
Kendrew, J.C.1
Dickerson, R.E.2
Strandberg, B.E.3
Hart, R.G.4
Davies, D.R.5
Phillips, D.C.6
Shore, V.C.7
-
24
-
-
13244291292
-
Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA
-
COI: 1:CAS:528:DC%2BD2MXpt1ajsw%3D%3D, PID: 15692043
-
Kim C, Xuong NH, Taylor SS (2005) Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA. Science 307(5710):690–696
-
(2005)
Science
, vol.307
, Issue.5710
, pp. 690-696
-
-
Kim, C.1
Xuong, N.H.2
Taylor, S.S.3
-
25
-
-
34548611290
-
PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation
-
COI: 1:CAS:528:DC%2BD2sXhtFKnurvJ, PID: 17889648
-
Kim C, Cheng CY, Saldanha SA, Taylor SS (2007) PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation. Cell 130(6):1032–1043
-
(2007)
Cell
, vol.130
, Issue.6
, pp. 1032-1043
-
-
Kim, C.1
Cheng, C.Y.2
Saldanha, S.A.3
Taylor, S.S.4
-
26
-
-
0026342401
-
Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase
-
COI: 1:CAS:528:DyaK3MXmsFSqsLw%3D, PID: 1862342
-
Knighton DR, Zheng JH, Ten Eyck LF, Ashford VA, Xuong NH, Taylor SS, Sowadski JM (1991) Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science 253(5018):407–414
-
(1991)
Science
, vol.253
, Issue.5018
, pp. 407-414
-
-
Knighton, D.R.1
Zheng, J.H.2
Ten Eyck, L.F.3
Ashford, V.A.4
Xuong, N.H.5
Taylor, S.S.6
Sowadski, J.M.7
-
27
-
-
42949174618
-
A generalized allosteric mechanism for cis-regulated cyclic nucleotide binding domains
-
PID: 18404204
-
Kornev AP, Taylor SS, Ten Eyck LF (2008) A generalized allosteric mechanism for cis-regulated cyclic nucleotide binding domains. PLoS Comput Biol 4(4):e1000056
-
(2008)
PLoS Comput Biol
, vol.4
, Issue.4
, pp. 1000056
-
-
Kornev, A.P.1
Taylor, S.S.2
Ten Eyck, L.F.3
-
28
-
-
70449285205
-
Factors affecting the activity of muscle phosphorylase B kinase
-
COI: 1:CAS:528:DyaF3cXitlGntg%3D%3D, PID: 14411853
-
Krebs EG, Graves DJ, Fischer EH (1959) Factors affecting the activity of muscle phosphorylase B kinase. J Biol Chem 234(11):2867–2873
-
(1959)
J Biol Chem
, vol.234
, Issue.11
, pp. 2867-2873
-
-
Krebs, E.G.1
Graves, D.J.2
Fischer, E.H.3
-
29
-
-
79958182720
-
Recurrent PRKAR1A mutation in acrodysostosis with hormone resistance
-
COI: 1:CAS:528:DC%2BC3MXnsV2ns7w%3D, PID: 21651393
-
Linglart A, Menguy C, Couvineau A, Auzan C, Gunes Y, Cancel M, Motte E, Pinto G, Chanson P, Bougneres P, Clauser E, Silve C (2011) Recurrent PRKAR1A mutation in acrodysostosis with hormone resistance. N Engl J Med 364(23):2218–2226
-
(2011)
N Engl J Med
, vol.364
, Issue.23
, pp. 2218-2226
-
-
Linglart, A.1
Menguy, C.2
Couvineau, A.3
Auzan, C.4
Gunes, Y.5
Cancel, M.6
Motte, E.7
Pinto, G.8
Chanson, P.9
Bougneres, P.10
Clauser, E.11
Silve, C.12
-
30
-
-
84929214844
-
-
Malmstrom R, Kornev AP, Taylor SS, Amaro R (2015) Allostery through conformational selection: cAMP regulation of the cyclic-nucleotide binding domain in PKA. Nat Commun (In press)
-
Malmstrom R, Kornev AP, Taylor SS, Amaro R (2015) Allostery through conformational selection: cAMP regulation of the cyclic-nucleotide binding domain in PKA. Nat Commun (In press)
-
-
-
-
31
-
-
34548610383
-
Isoform-specific PKA dynamics revealed by dye-triggered aggregation and DAKAP1alpha-mediated localization in living cells
-
COI: 1:CAS:528:DC%2BD2sXhtVOnsr7K, PID: 17884635
-
Martin BR, Deerinck TJ, Ellisman MH, Taylor SS, Tsien RY (2007) Isoform-specific PKA dynamics revealed by dye-triggered aggregation and DAKAP1alpha-mediated localization in living cells. Chem Biol 14(9):1031–1042
-
(2007)
Chem Biol
, vol.14
, Issue.9
, pp. 1031-1042
-
-
Martin, B.R.1
Deerinck, T.J.2
Ellisman, M.H.3
Taylor, S.S.4
Tsien, R.Y.5
-
32
-
-
78651189765
-
On the nature of allosteric transitions: a plausible model
-
COI: 1:CAS:528:DyaF2MXkt1Ghsb4%3D, PID: 14343300
-
Monod J, Wyman J, Changeux JP (1965) On the nature of allosteric transitions: a plausible model. J Mol Biol 12:88–118
-
(1965)
J Mol Biol
, vol.12
, pp. 88-118
-
-
Monod, J.1
Wyman, J.2
Changeux, J.P.3
-
33
-
-
36949066642
-
Structure of haemoglobin: a three-dimensional Fourier synthesis at 5.5-A. resolution, obtained by X-ray analysis
-
COI: 1:CAS:528:DyaF3cXotVynsQ%3D%3D, PID: 18990801
-
Perutz MF, Rossmann MG, Cullis AF, Muirhead H, Will G, North AC (1960) Structure of haemoglobin: a three-dimensional Fourier synthesis at 5.5-A. resolution, obtained by X-ray analysis. Nature 185(4711):416–422
-
(1960)
Nature
, vol.185
, Issue.4711
, pp. 416-422
-
-
Perutz, M.F.1
Rossmann, M.G.2
Cullis, A.F.3
Muirhead, H.4
Will, G.5
North, A.C.6
-
34
-
-
0000413412
-
Formation of a cyclic adenine ribonucleotide by tissue particles
-
COI: 1:CAS:528:DyaG1cXhtVCktbw%3D, PID: 13549487
-
Rall TW, Sutherland EW (1958) Formation of a cyclic adenine ribonucleotide by tissue particles. J Biol Chem 232(2):1065–1076
-
(1958)
J Biol Chem
, vol.232
, Issue.2
, pp. 1065-1076
-
-
Rall, T.W.1
Sutherland, E.W.2
-
35
-
-
78149460164
-
Structure of yeast regulatory subunit: a glimpse into the evolution of PKA signaling
-
COI: 1:CAS:528:DC%2BC3cXhsValtbvF, PID: 21070946
-
Rinaldi J, Wu J, Yang J, Ralston CY, Sankaran B, Moreno S, Taylor SS (2010) Structure of yeast regulatory subunit: a glimpse into the evolution of PKA signaling. Structure 18(11):1471–1482
-
(2010)
Structure
, vol.18
, Issue.11
, pp. 1471-1482
-
-
Rinaldi, J.1
Wu, J.2
Yang, J.3
Ralston, C.Y.4
Sankaran, B.5
Moreno, S.6
Taylor, S.S.7
-
36
-
-
67650082449
-
A chimeric mechanism for polyvalent trans-phosphorylation of PKA by PDK1
-
COI: 1:CAS:528:DC%2BD1MXnvVChsLg%3D, PID: 19530248
-
Romano RA, Kannan N, Kornev AP, Allison CJ, Taylor SS (2009) A chimeric mechanism for polyvalent trans-phosphorylation of PKA by PDK1. Protein Sci 18(7):1486–1497
-
(2009)
Protein Sci
, vol.18
, Issue.7
, pp. 1486-1497
-
-
Romano, R.A.1
Kannan, N.2
Kornev, A.P.3
Allison, C.J.4
Taylor, S.S.5
-
37
-
-
0016605553
-
Properties of the cyclid AMP-dependent protein kinase from bovine and porcine heart
-
COI: 1:CAS:528:DyaE28Xislansw%3D%3D
-
Rosen OM, Rubin CS, Erlighman J (1975) Properties of the cyclid AMP-dependent protein kinase from bovine and porcine heart. Adv Enzym Regul 13:173–185
-
(1975)
Adv Enzym Regul
, vol.13
, pp. 173-185
-
-
Rosen, O.M.1
Rubin, C.S.2
Erlighman, J.3
-
38
-
-
0035516189
-
Mutation of the RIIbeta subunit of protein kinase A prevents diet-induced insulin resistance and dyslipidemia in mice
-
COI: 1:CAS:528:DC%2BD3MXotFGis7o%3D, PID: 11679434
-
Schreyer SA, Cummings DE, McKnight GS, LeBoeuf RC (2001) Mutation of the RIIbeta subunit of protein kinase A prevents diet-induced insulin resistance and dyslipidemia in mice. Diabetes 50(11):2555–2562
-
(2001)
Diabetes
, vol.50
, Issue.11
, pp. 2555-2562
-
-
Schreyer, S.A.1
Cummings, D.E.2
McKnight, G.S.3
LeBoeuf, R.C.4
-
39
-
-
84887346558
-
Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation
-
PID: 24192038
-
Smith FD, Reichow SL, Esseltine JL, Shi D, Langeberg LK, Scott JD, Gonen T (2013) Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation. Elife 2:e01319
-
(2013)
Elife
, vol.2
, pp. 01319
-
-
Smith, F.D.1
Reichow, S.L.2
Esseltine, J.L.3
Shi, D.4
Langeberg, L.K.5
Scott, J.D.6
Gonen, T.7
-
40
-
-
0029143803
-
Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains
-
COI: 1:CAS:528:DyaK2MXnsVahsbc%3D, PID: 7638597
-
Su Y, Dostmann WR, Herberg FW, Durick K, Xuong NH, Ten Eyck L, Taylor SS, Varughese KI (1995) Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains. Science 269(5225):807–813
-
(1995)
Science
, vol.269
, Issue.5225
, pp. 807-813
-
-
Su, Y.1
Dostmann, W.R.2
Herberg, F.W.3
Durick, K.4
Xuong, N.H.5
Ten Eyck, L.6
Taylor, S.S.7
Varughese, K.I.8
-
41
-
-
0014850393
-
Mechanism of activation by adenosine 3′:5′-cyclic monophosphate of a protein phosphokinase from rabbit reticulocytes
-
COI: 1:CAS:528:DyaE3cXlt1OhsLw%3D, PID: 4318788
-
Tao M, Salas ML, Lipmann F (1970) Mechanism of activation by adenosine 3′:5′-cyclic monophosphate of a protein phosphokinase from rabbit reticulocytes. Proc Natl Acad Sci USA 67(1):408–414
-
(1970)
Proc Natl Acad Sci USA
, vol.67
, Issue.1
, pp. 408-414
-
-
Tao, M.1
Salas, M.L.2
Lipmann, F.3
-
42
-
-
84866729606
-
Assembly of allosteric macromolecular switches: lessons from PKA
-
COI: 1:CAS:528:DC%2BC38XhtlKrsb7P, PID: 22992589
-
Taylor SS, Ilouz R, Zhang P, Kornev AP (2012) Assembly of allosteric macromolecular switches: lessons from PKA. Nat Rev Mol Cell Biol 13(10):646–658
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, Issue.10
, pp. 646-658
-
-
Taylor, S.S.1
Ilouz, R.2
Zhang, P.3
Kornev, A.P.4
-
43
-
-
1842575826
-
Conformational differences among solution structures of the type Ialpha, IIalpha and IIbeta protein kinase A regulatory subunit homodimers: role of the linker regions
-
COI: 1:CAS:528:DC%2BD2cXisVSmsbk%3D, PID: 15046986
-
Vigil D, Blumenthal DK, Heller WT, Brown S, Canaves JM, Taylor SS, Trewhella J (2004) Conformational differences among solution structures of the type Ialpha, IIalpha and IIbeta protein kinase A regulatory subunit homodimers: role of the linker regions. J Mol Biol 337(5):1183–1194
-
(2004)
J Mol Biol
, vol.337
, Issue.5
, pp. 1183-1194
-
-
Vigil, D.1
Blumenthal, D.K.2
Heller, W.T.3
Brown, S.4
Canaves, J.M.5
Taylor, S.S.6
Trewhella, J.7
-
44
-
-
33644932999
-
Solution scattering reveals large differences in the global structures of type II protein kinase A isoforms
-
COI: 1:CAS:528:DC%2BD28XisFyitL0%3D, PID: 16460759
-
Vigil D, Blumenthal DK, Taylor SS, Trewhella J (2006) Solution scattering reveals large differences in the global structures of type II protein kinase A isoforms. J Mol Biol 357(3):880–889
-
(2006)
J Mol Biol
, vol.357
, Issue.3
, pp. 880-889
-
-
Vigil, D.1
Blumenthal, D.K.2
Taylor, S.S.3
Trewhella, J.4
-
45
-
-
0014409394
-
An adenosine 3′,5′-monophosphate-dependant protein kinase from rabbit skeletal muscle
-
COI: 1:CAS:528:DyaF1cXkt1Cks7w%3D, PID: 4298072
-
Walsh DA, Perkins JP, Krebs EG (1968) An adenosine 3′,5′-monophosphate-dependant protein kinase from rabbit skeletal muscle. J Biol Chem 243(13):3763–3765
-
(1968)
J Biol Chem
, vol.243
, Issue.13
, pp. 3763-3765
-
-
Walsh, D.A.1
Perkins, J.P.2
Krebs, E.G.3
-
46
-
-
0026098899
-
A constitutively active holoenzyme form of the cAMP-dependent protein kinase
-
COI: 1:CAS:528:DyaK3MXhvVWht7k%3D, PID: 1848703
-
Wang YH, Scott JD, McKnight GS, Krebs EG (1991) A constitutively active holoenzyme form of the cAMP-dependent protein kinase. Proc Natl Acad Sci USA 88(6):2446–2450
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, Issue.6
, pp. 2446-2450
-
-
Wang, Y.H.1
Scott, J.D.2
McKnight, G.S.3
Krebs, E.G.4
-
47
-
-
10044253425
-
AKAP signalling complexes: focal points in space and time
-
COI: 1:CAS:528:DC%2BD2cXhtVarsbzJ, PID: 15573134
-
Wong W, Scott JD (2004) AKAP signalling complexes: focal points in space and time. Nat Rev Mol Cell Biol 5(12):959–970
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, Issue.12
, pp. 959-970
-
-
Wong, W.1
Scott, J.D.2
-
48
-
-
84899803622
-
PRKAR1B mutation associated with a new neurodegenerative disorder with unique pathology
-
PID: 24722252
-
Wong TH, Chiu WZ, Breedveld GJ, Li KW, Verkerk AJ, Hondius D, Hukema RK, Seelaar H, Frick P, Severijnen LA, Lammers GJ, Lebbink JH, van Duinen SG, Kamphorst W, Rozemuller AJ, Bakker EB, Neumann M, Willemsen R, Bonifati V, Smit AB, van Swieten J (2014) PRKAR1B mutation associated with a new neurodegenerative disorder with unique pathology. Brain 137(Pt 5):1361–1373
-
(2014)
Brain
, vol.137
, pp. 1361-1373
-
-
Wong, T.H.1
Chiu, W.Z.2
Breedveld, G.J.3
Li, K.W.4
Verkerk, A.J.5
Hondius, D.6
Hukema, R.K.7
Seelaar, H.8
Frick, P.9
Severijnen, L.A.10
Lammers, G.J.11
Lebbink, J.H.12
van Duinen, S.G.13
Kamphorst, W.14
Rozemuller, A.J.15
Bakker, E.B.16
Neumann, M.17
Willemsen, R.18
Bonifati, V.19
Smit, A.B.20
van Swieten, J.21
more..
-
49
-
-
35348885465
-
PKA type IIalpha holoenzyme reveals a combinatorial strategy for isoform diversity
-
COI: 1:CAS:528:DC%2BD2sXhtFCjt7rK, PID: 17932298
-
Wu J, Brown SH, von Daake S, Taylor SS (2007) PKA type IIalpha holoenzyme reveals a combinatorial strategy for isoform diversity. Science 318(5848):274–279
-
(2007)
Science
, vol.318
, Issue.5848
, pp. 274-279
-
-
Wu, J.1
Brown, S.H.2
von Daake, S.3
Taylor, S.S.4
-
50
-
-
1342325388
-
cAMP-dependent protein kinase regulatory subunit type IIbeta: active site mutations define an isoform-specific network for allosteric signaling by cAMP
-
COI: 1:CAS:528:DC%2BD2cXht1Cks7o%3D, PID: 14625280
-
Zawadzki KM, Taylor SS (2004) cAMP-dependent protein kinase regulatory subunit type IIbeta: active site mutations define an isoform-specific network for allosteric signaling by cAMP. J Biol Chem 279(8):7029–7036
-
(2004)
J Biol Chem
, vol.279
, Issue.8
, pp. 7029-7036
-
-
Zawadzki, K.M.1
Taylor, S.S.2
-
51
-
-
84856983194
-
Structure and allostery of the PKA RIIbeta tetrameric holoenzyme
-
COI: 1:CAS:528:DC%2BC38XhvVCjs78%3D, PID: 22323819
-
Zhang P, Smith-Nguyen EV, Keshwani MM, Deal MS, Kornev AP, Taylor SS (2012) Structure and allostery of the PKA RIIbeta tetrameric holoenzyme. Science 335(6069):712–716
-
(2012)
Science
, vol.335
, Issue.6069
, pp. 712-716
-
-
Zhang, P.1
Smith-Nguyen, E.V.2
Keshwani, M.M.3
Deal, M.S.4
Kornev, A.P.5
Taylor, S.S.6
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