-
1
-
-
0030614908
-
Compensatory regulation of RIalpha protein levels in protein kinase A mutant mice
-
DOI 10.1074/jbc.272.7.3993
-
Amieux PS, et al. (1997) Compensatory regulation of RIalpha protein levels in protein kinase A mutant mice. J Biol Chem 272:3993-3998. (Pubitemid 27078459)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.7
, pp. 3993-3998
-
-
Amieux, P.S.1
Cummings, D.E.2
Motamed, K.3
Brandon, E.P.4
Wailes, L.A.5
Le, K.6
Idzerda, R.L.7
Stanley M.Knight, G.8
-
2
-
-
0024218550
-
Analysis of the cAMP-dependent protein kinase system using molecular genetic approaches
-
McKnight GS, et al. (1988) Analysis of the cAMP-dependent protein kinase system using molecular genetic approaches. Recent Prog Horm Res 44:307-335.
-
(1988)
Recent Prog Horm Res
, vol.44
, pp. 307-335
-
-
McKnight, G.S.1
-
3
-
-
0011564219
-
Genetic characterization of a brain-specific form of the type I regulatory subunit of cAMP-dependent protein kinase
-
Clegg CH, Cadd GG, McKnight GS (1988) Genetic characterization of a brain-specific form of the type I regulatory subunit of cAMP-dependent protein kinase. Proc Natl Acad Sci USA 85:3703-3707.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 3703-3707
-
-
Clegg, C.H.1
Cadd, G.G.2
McKnight, G.S.3
-
4
-
-
0025915104
-
Molecular cloning, cDNA structure and tissue-specific expression of the human regulatory subunit RI beta of cAMP-dependent protein kinases
-
Solberg R, Taskén K, Keiserud A, Jahnsen T (1991) Molecular cloning, cDNA structure and tissue-specific expression of the human regulatory subunit RI beta of cAMP-dependent protein kinases. Biochem Biophys Res Commun 176:166-172.
-
(1991)
Biochem Biophys Res Commun
, vol.176
, pp. 166-172
-
-
Solberg, R.1
Taskén, K.2
Keiserud, A.3
Jahnsen, T.4
-
5
-
-
0024695482
-
Distinct patterns of cAMP-dependent protein kinase gene expression in mouse brain
-
Cadd G, McKnight GS (1989) Distinct patterns of cAMP-dependent protein kinase gene expression in mouse brain. Neuron 3:71-79.
-
(1989)
Neuron
, vol.3
, pp. 71-79
-
-
Cadd, G.1
McKnight, G.S.2
-
6
-
-
0029021176
-
Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase
-
Brandon EP, et al. (1995) Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase. Proc Natl Acad Sci USA 92:8851-8855.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8851-8855
-
-
Brandon, E.P.1
-
7
-
-
13344279399
-
A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning
-
Huang YY, et al. (1995) A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning. Cell 83:1211-1222.
-
(1995)
Cell
, vol.83
, pp. 1211-1222
-
-
Huang, Y.Y.1
-
8
-
-
10044253425
-
AKAP signalling complexes: Focal points in space and time
-
DOI 10.1038/nrm1527
-
Wong W, Scott JD (2004) AKAP signalling complexes: Focal points in space and time. Nat Rev Mol Cell Biol 5:959-970. (Pubitemid 39611533)
-
(2004)
Nature Reviews Molecular Cell Biology
, vol.5
, Issue.12
, pp. 959-970
-
-
Wong, W.1
Scott, J.D.2
-
9
-
-
3042611874
-
Merlin Links to the cAMP Neuronal Signaling Pathway by Anchoring the RIbeta Subunit of Protein Kinase A
-
DOI 10.1074/jbc.M306149200
-
Grönholm M, et al. (2003) Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A. J Biol Chem 278:41167-41172. (Pubitemid 37280942)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.42
, pp. 41167-41172
-
-
Gronholm, M.1
Vossebein, L.2
Carlson, C.R.3
Kuja-Panula, J.4
Teesalu, T.5
Alfthan, K.6
Vaheri, A.7
Rauvala, H.8
Herberg, F.W.9
Tasken, K.10
Carpen, O.11
-
10
-
-
0025221258
-
Holoenzymes of cAMP-dependent protein kinase containing the neural form of type I regulatory subunit have an increased sensitivity to cyclic nucleotides
-
Cadd GG, Uhler MD, McKnight GS (1990) Holoenzymes of cAMP-dependent protein kinase containing the neural form of type I regulatory subunit have an increased sensitivity to cyclic nucleotides. J Biol Chem 265:19502-19506. (Pubitemid 120013892)
-
(1990)
Journal of Biological Chemistry
, vol.265
, Issue.32
, pp. 19502-19506
-
-
Cadd, G.G.1
Uhler, M.D.2
McKnight, G.S.3
-
11
-
-
1342325388
-
cAMP-dependent protein kinase regulatory subunit type IIbeta: Active site mutations define an isoform-specific network for allosteric signaling by cAMP
-
DOI 10.1074/jbc.M310804200
-
Zawadzki KM, Taylor SS (2004) cAMP-dependent protein kinase regulatory subunit type IIbeta: Active site mutations define an isoform-specific network for allosteric signaling by cAMP. J Biol Chem 279:7029-7036. (Pubitemid 38248848)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.8
, pp. 7029-7036
-
-
Zawadzki, K.M.1
Taylor, S.S.2
-
12
-
-
70350025561
-
Novel isoform-specific interfaces revealed by PKA RIIbeta holoenzyme structures
-
Brown SH, Wu J, Kim C, Alberto K, Taylor SS (2009) Novel isoform-specific interfaces revealed by PKA RIIbeta holoenzyme structures. J Mol Biol 393:1070-1082.
-
(2009)
J Mol Biol
, vol.393
, pp. 1070-1082
-
-
Brown, S.H.1
Wu, J.2
Kim, C.3
Alberto, K.4
Taylor, S.S.5
-
13
-
-
34548611290
-
PKA-I Holoenzyme Structure Reveals a Mechanism for cAMP-Dependent Activation
-
DOI 10.1016/j.cell.2007.07.018, PII S0092867407009555
-
Kim C, Cheng CY, Saldanha SA, Taylor SS (2007) PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation. Cell 130:1032-1043. (Pubitemid 47410267)
-
(2007)
Cell
, vol.130
, Issue.6
, pp. 1032-1043
-
-
Kim, C.1
Cheng, C.Y.2
Saldanha, S.A.3
Taylor, S.S.4
-
14
-
-
35348885465
-
PKA type IIalpha holoenzyme reveals a combinatorial strategy for isoform diversity
-
DOI 10.1126/science.1146447
-
Wu J, Brown SH, von Daake S, Taylor SS (2007) PKA type IIalpha holoenzyme reveals a combinatorial strategy for isoform diversity. Science 318:274-279. (Pubitemid 47574855)
-
(2007)
Science
, vol.318
, Issue.5848
, pp. 274-279
-
-
Wu, J.1
Brown, S.H.J.2
Von Daake, S.3
Taylor, S.S.4
-
15
-
-
1842508814
-
C Subunits Binding to the Protein Kinase A RI alpha Dimer Induce a Large Conformational Change
-
DOI 10.1074/jbc.M313405200
-
Heller WT, et al. (2004) C subunits binding to the protein kinase A RI alpha dimer induce a large conformational change. J Biol Chem 279:19084-19090. (Pubitemid 38623339)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.18
, pp. 19084-19090
-
-
Heller, W.T.1
Vigil, D.2
Brown, S.3
Blumenthal, D.K.4
Taylor, S.S.5
Trewhella, J.6
-
16
-
-
33644932999
-
Solution scattering reveals large differences in the global structures of type II protein kinase A isoforms
-
Vigil D, Blumenthal DK, Taylor SS, Trewhella J (2006) Solution scattering reveals large differences in the global structures of type II protein kinase A isoforms. J Mol Biol 357:880-889.
-
(2006)
J Mol Biol
, vol.357
, pp. 880-889
-
-
Vigil, D.1
Blumenthal, D.K.2
Taylor, S.S.3
Trewhella, J.4
-
17
-
-
79551691294
-
Realizing the allosteric potential of the tetrameric protein kinase A RIα holoenzyme
-
Boettcher AJ, et al. (2011) Realizing the allosteric potential of the tetrameric protein kinase A RIα holoenzyme. Structure 19:265-276.
-
(2011)
Structure
, vol.19
, pp. 265-276
-
-
Boettcher, A.J.1
-
18
-
-
84856983194
-
Structure and allostery of the PKA RIIβ tetrameric holoenzyme
-
Zhang P, et al. (2012) Structure and allostery of the PKA RIIβ tetrameric holoenzyme. Science 335:712-716.
-
(2012)
Science
, vol.335
, pp. 712-716
-
-
Zhang, P.1
-
19
-
-
0028328869
-
Location of cAMP-dependent protein kinase type I with the TCR-CD3 complex
-
Skålhegg BS, et al. (1994) Location of cAMP-dependent protein kinase type I with the TCR-CD3 complex. Science 263:84-87. (Pubitemid 24076260)
-
(1994)
Science
, vol.263
, Issue.5143
, pp. 84-87
-
-
Skalhegg, B.S.1
Tasken, K.2
Hansson, V.3
Huitfeldt, H.S.4
Jahnsen, T.5
Lea, T.6
-
20
-
-
33746922414
-
Oxidant-induced activation of type I protein kinase A is mediated by RI subunit interprotein disulfide bond formation
-
DOI 10.1074/jbc.M603952200
-
Brennan JP, et al. (2006) Oxidant-induced activation of type I protein kinase A is mediated by RI subunit interprotein disulfide bond formation. J Biol Chem 281:21827-21836. (Pubitemid 44191910)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.31
, pp. 21827-21836
-
-
Brennan, J.P.1
Bardswell, S.C.2
Burgoyne, J.R.3
Fuller, W.4
Schroder, E.5
Wait, R.6
Begum, S.7
Kentish, J.C.8
Eaton, P.9
-
21
-
-
13244291292
-
Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA
-
DOI 10.1126/science.1104607
-
Kim C, Xuong NH, Taylor SS (2005) Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA. Science 307:690-696. (Pubitemid 40194632)
-
(2005)
Science
, vol.307
, Issue.5710
, pp. 690-696
-
-
Kim, C.1
Xuong, N.-H.2
Taylor, S.S.3
-
22
-
-
0000127673
-
2.2 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor
-
Zheng J, et al. (1993) 2.2 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor. Acta Crystallogr D Biol Crystallogr 49:362-365.
-
(1993)
Acta Crystallogr D Biol Crystallogr
, vol.49
, pp. 362-365
-
-
Zheng, J.1
-
23
-
-
0034625161
-
Snapping of the carboxyl terminal tail of the catalytic subunit of PKA onto its core: Characterization of the sites by mutagenesis
-
DOI 10.1021/bi000153z
-
Batkin M, Schvartz I, Shaltiel S (2000) Snapping of the carboxyl terminal tail of the catalytic subunit of PKA onto its core: Characterization of the sites by mutagenesis. Biochemistry 39:5366-5373. (Pubitemid 30257076)
-
(2000)
Biochemistry
, vol.39
, Issue.18
, pp. 5366-5373
-
-
Batkin, M.1
Schvartz, I.2
Shaltiel, S.3
-
24
-
-
33947226782
-
Structural and functional diversity of the microbial kinome
-
Kannan N, Taylor SS, Zhai Y, Venter JC, Manning G (2007) Structural and functional diversity of the microbial kinome. PLoS Biol 5:e17.
-
(2007)
PLoS Biol
, vol.5
-
-
Kannan, N.1
Taylor, S.S.2
Zhai, Y.3
Venter, J.C.4
Manning, G.5
-
25
-
-
33846590132
-
The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module
-
DOI 10.1073/pnas.0610251104
-
Kannan N, Haste N, Taylor SS, Neuwald AF (2007) The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module. Proc Natl Acad Sci USA 104:1272-1277. (Pubitemid 46183994)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.4
, pp. 1272-1277
-
-
Kannan, N.1
Haste, N.2
Taylor, S.S.3
Neuwald, A.F.4
-
26
-
-
65249108791
-
Contribution of non-catalytic core residues to activity and regulation in protein kinase A
-
Yang J, et al. (2009) Contribution of non-catalytic core residues to activity and regulation in protein kinase A. J Biol Chem 284:6241-6248.
-
(2009)
J Biol Chem
, vol.284
, pp. 6241-6248
-
-
Yang, J.1
-
27
-
-
62749134006
-
Identifying critical non-catalytic residues that modulate protein kinase A activity
-
Kennedy EJ, Yang J, Pillus L, Taylor SS, Ghosh G (2009) Identifying critical non-catalytic residues that modulate protein kinase A activity. PLoS ONE 4:e4746.
-
(2009)
PLoS ONE
, vol.4
-
-
Kennedy, E.J.1
Yang, J.2
Pillus, L.3
Taylor, S.S.4
Ghosh, G.5
-
28
-
-
0037102153
-
High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site
-
Biondi RM, et al. (2002) High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site. EMBO J 21:4219-4228.
-
(2002)
EMBO J
, vol.21
, pp. 4219-4228
-
-
Biondi, R.M.1
-
29
-
-
78650942010
-
Crystal structure and allosteric activation of protein kinase C βII
-
Leonard TA, Różycki B, Saidi LF, Hummer G, Hurley JH (2011) Crystal structure and allosteric activation of protein kinase C βII. Cell 144:55-66.
-
(2011)
Cell
, vol.144
, pp. 55-66
-
-
Leonard, T.A.1
Rózycki, B.2
Saidi, L.F.3
Hummer, G.4
Hurley, J.H.5
-
30
-
-
84859765114
-
Peptidyl-prolyl isomerase Pin1 controls down-regulation of conventional protein kinase C isozymes
-
Abrahamsen H, et al. (2012) Peptidyl-prolyl isomerase Pin1 controls down-regulation of conventional protein kinase C isozymes. J Biol Chem 287:13262-13278.
-
(2012)
J Biol Chem
, vol.287
, pp. 13262-13278
-
-
Abrahamsen, H.1
-
31
-
-
64149128633
-
The chaperones Hsp90 and Cdc37 mediate the maturation and stabilization of protein kinase C through a conserved PXXP motif in the C-terminal tail
-
Gould CM, Kannan N, Taylor SS, Newton AC (2009) The chaperones Hsp90 and Cdc37 mediate the maturation and stabilization of protein kinase C through a conserved PXXP motif in the C-terminal tail. J Biol Chem 284:4921-4935.
-
(2009)
J Biol Chem
, vol.284
, pp. 4921-4935
-
-
Gould, C.M.1
Kannan, N.2
Taylor, S.S.3
Newton, A.C.4
-
32
-
-
0037675779
-
Related protein - Protein interaction modules present drastically different surface topographies despite A conserved helical platform
-
DOI 10.1016/S0022-2836(03)00552-7
-
Banky P, et al. (2003) Related protein-protein interaction modules present drastically different surface topographies despite a conserved helical platform. J Mol Biol 330:1117-1129. (Pubitemid 36818907)
-
(2003)
Journal of Molecular Biology
, vol.330
, Issue.5
, pp. 1117-1129
-
-
Banky, P.1
Roy, M.2
Newlon, M.G.3
Morikis, D.4
Haste, N.M.5
Taylor, S.S.6
Jennings, P.A.7
-
33
-
-
0035794551
-
A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes
-
DOI 10.1093/emboj/20.7.1651
-
Newlon MG, et al. (2001) A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes. EMBO J 20:1651-1662. (Pubitemid 32299402)
-
(2001)
EMBO Journal
, vol.20
, Issue.7
, pp. 1651-1662
-
-
Newlon, M.G.1
Roy, M.2
Morikis, D.3
Carr, D.W.4
Westphal, R.5
Scott, J.D.6
Jennings, P.A.7
-
34
-
-
75849127506
-
Structure of D-AKAP2:PKA RI complex: Insights into AKAP specificity and selectivity
-
Sarma GN, et al. (2010) Structure of D-AKAP2:PKA RI complex: Insights into AKAP specificity and selectivity. Structure 18:155-166.
-
(2010)
Structure
, vol.18
, pp. 155-166
-
-
Sarma, G.N.1
-
35
-
-
0032813671
-
Structural characterization of the membrane-associated regulatory subunit of type I cAMP-dependent protein kinase by mass spectrometry: Identification of Ser81 as the in vivo phosphorylation site of RIalpha
-
Boeshans KM, Resing KA, Hunt JB, Ahn NG, Shabb JB (1999) Structural characterization of the membrane-associated regulatory subunit of type I cAMP-dependent protein kinase by mass spectrometry: Identification of Ser81 as the in vivo phosphorylation site of RIalpha. Protein Sci 8:1515-1522. (Pubitemid 29328233)
-
(1999)
Protein Science
, vol.8
, Issue.7
, pp. 1515-1522
-
-
Boeshans, K.M.1
Resing, K.A.2
Hunt, J.B.3
Ahn, N.G.4
Shabb, J.B.5
-
36
-
-
79551594605
-
Protein kinases: Evolution of dynamic regulatory proteins
-
Taylor SS, Kornev AP (2011) Protein kinases: Evolution of dynamic regulatory proteins. Trends Biochem Sci 36:65-77.
-
(2011)
Trends Biochem Sci
, vol.36
, pp. 65-77
-
-
Taylor, S.S.1
Kornev, A.P.2
-
37
-
-
0026326821
-
Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase
-
Knighton DR, et al. (1991) Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science 253:414-420. (Pubitemid 21917166)
-
(1991)
Science
, vol.253
, Issue.5018
, pp. 414-420
-
-
Knighton, D.R.1
Zheng, J.2
Ten, E.L.F.3
Xuong, N.-H.4
Taylor, S.S.5
Sowadski, J.M.6
-
39
-
-
0030881687
-
D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domain
-
DOI 10.1073/pnas.94.21.11184
-
Huang LJ, Durick K, Weiner JA, Chun J, Taylor SS (1997) D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domain. Proc Natl Acad Sci USA 94:11184-11189. (Pubitemid 27450972)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.21
, pp. 11184-11189
-
-
Huang, L.J.-S.1
Durick, K.2
Weiner, J.A.3
Chun, J.4
Taylor, S.S.5
-
40
-
-
67449105851
-
Selectivity in enrichment of cAMP-dependent protein kinase regulatory subunits type I and type II and their interactors using modified cAMP affinity resins
-
Aye TT, et al. (2009) Selectivity in enrichment of cAMP-dependent protein kinase regulatory subunits type I and type II and their interactors using modified cAMP affinity resins. Mol Cell Proteomics 8:1016-1028.
-
(2009)
Mol Cell Proteomics
, vol.8
, pp. 1016-1028
-
-
Aye, T.T.1
-
41
-
-
0032878514
-
Single amino acids determine specificity of binding of protein kinase A regulatory subunits by protein kinase A anchoring proteins
-
Miki K, Eddy EM (1999) Single amino acids determine specificity of binding of protein kinase A regulatory subunits by protein kinase A anchoring proteins. J Biol Chem 274:29057-29062.
-
(1999)
J Biol Chem
, vol.274
, pp. 29057-29062
-
-
Miki, K.1
Eddy, E.M.2
|