Signaling through dynamic linkers as revealed by PKA

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 35, 2013, Pages 14231-14236

  Akimoto, Madoka ^a   Selvaratnam, Rajeevan ^a   Tyler McNicholl, E ^a   Verma, Geeta ^a   Taylor, Susan S ^b,c,d   Melacini, Giuseppe ^a,e  

^a Department of Chemistry and Chemical Biology ^*  (Canada)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c Departments of Chemistry and Biochemistry   (United States)

^d San Diego   (United States)

^e MCMASTER UNIVERSITY   (Canada)

Author keywords

Allostery; CAMP; Dynamics; Intrinsically disordered proteins; NMR

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE;

ARTICLE; CONFORMATIONAL TRANSITION; ENERGY; ENZYME ACTIVATION; ENZYME INHIBITION; FLUORESCENCE; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; SIGNAL TRANSDUCTION;

ALLOSTERY; CAMP; DYNAMICS; INTRINSICALLY DISORDERED PROTEINS; NMR;

ALLOSTERIC REGULATION; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASE RIALPHA SUBUNIT; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; SIGNAL TRANSDUCTION;

EID: 84883397614     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1312644110     Document Type: Article

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