Exogenous induction of HO-1 alleviates vincristine-induced neuropathic pain by reducing spinal glial activation in mice

Neurobiology of Disease

Volumn 79, Issue , 2015, Pages 100-110

  Shen, Yan ^a   Zhang, Zhi Jun ^a,b   Zhu, Ming Di ^a   Jiang, Bao Chun ^a   Yang, Tian ^a   Gao, Yong Jing ^a  

^a NANTONG UNIVERSITY   (China)

^b NANTONG MEDICAL COLLEGE   (China)

Author keywords

Astrocytes; Chemotherapy induced pain; Heme oxygenase 1; Mice; Microglia; Mitogen activated protein kinase; Neuroinflammation; Spinal cord; Vincristine

Indexed keywords

ENZYME INDUCING AGENT; HEME OXYGENASE 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTOPORPHYRIN IX COBALT CHLORIDE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VINCRISTINE; ANTINEOPLASTIC AGENT; ENZYME ACTIVATOR; HMOX1 PROTEIN, MOUSE; MEMBRANE PROTEIN; NONSTEROID ANTIINFLAMMATORY AGENT; PROTOPORPHYRIN;

ADULT; ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GLIA CELL; HO 1 GENE; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; MALE; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEUROMODULATION; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPINAL CORD DORSAL HORN; ANIMAL; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; ENZYMOLOGY; GENE THERAPY; GENETICS; GLIA; IMMUNOLOGY; INSTITUTE FOR CANCER RESEARCH MOUSE; LENTIVIRINAE; METABOLISM; NERVE CELL; NEURALGIA; PAIN; PERIPHERAL NERVOUS SYSTEM DISEASES; SPINAL CORD;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTINEOPLASTIC AGENTS, PHYTOGENIC; DISEASE MODELS, ANIMAL; ENZYME ACTIVATORS; GENETIC THERAPY; HEME OXYGENASE-1; HYPERALGESIA; LENTIVIRUS; MALE; MEMBRANE PROTEINS; MICE, INBRED ICR; NEURALGIA; NEUROGLIA; NEURONS; PAIN; PERIPHERAL NERVOUS SYSTEM DISEASES; PROTOPORPHYRINS; RNA, MESSENGER; SPINAL CORD; VINCRISTINE;

EID: 84929172861     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2015.04.012     Document Type: Article

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