An ALS-mutant TDP-43 neurotoxic peptide adopts an anti-parallel β-structure and induces TDP-43 redistribution

Human Molecular Genetics

Volumn 23, Issue 25, 2014, Pages 6863-6877

  Zhu, Li ^a   Xu, Meng ^b,f   Yang, Mengxue ^a,c,e   Yang, Yanlian ^b   Li, Yang ^d,e   Deng, Jianwen ^a,c   Ruan, Linhao ^a,c   Liu, Jianghong ^a   Du, Sidan ^d,e   Liu, Xuehui ^a   Feng, Wei ^a   Fushimi, Kazuo ^e   Bigio, Eileen H ^e   Mesulam, Marsel ^e   Wang, Chen ^b   Wu, Jane Y ^a,e  

^a INSTITUTE OF BIOPHYSICS   (China)

^b NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^d NANJING UNIVERSITY   (China)

^e NORTHWESTERN UNIVERSITY   (United States)

^f PEKING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; DNA BINDING PROTEIN; PROTEIN TDP-43;

AMINO ACID SEQUENCE; ANIMAL; BRAIN CORTEX; CELL DEATH; CELL NUCLEUS; CHEMISTRY; CYTOPLASM; DRUG EFFECTS; HEK293 CELL LINE; HUMAN; METABOLISM; MICROFLUIDIC ANALYSIS; MOLECULAR GENETICS; NERVE CELL; PATHOLOGY; PRIMARY CELL CULTURE; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; RAT; SYNTHESIS; TDP 43 PROTEINOPATHY;

AMINO ACID SEQUENCE; AMYLOID BETA-PEPTIDES; ANIMALS; CELL DEATH; CELL NUCLEUS; CEREBRAL CORTEX; CYTOPLASM; DNA-BINDING PROTEINS; HEK293 CELLS; HUMANS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MOLECULAR SEQUENCE DATA; NEURONS; PRIMARY CELL CULTURE; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RATS; TDP-43 PROTEINOPATHIES;

EID: 84929126317     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu409     Document Type: Article

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