Interaction between mesenchymal stem cells and endothelial cells restores endothelial permeability via paracrine hepatocyte growth factor in vitro

Stem Cell Research and Therapy

Volumn 6, Issue 1, 2015, Pages

  Chen, Qi Hong ^a   Liu, Ai Ran ^a   Qiu, Hai Bo ^a   Yang, Yi ^a  

^a SOUTHEAST UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CAVEOLIN 1; F ACTIN; LIPOPOLYSACCHARIDE; OCCLUDIN; SCATTER FACTOR; VASCULAR ENDOTHELIAL CADHERIN; ACTIN; CADHERIN; HGF PROTEIN, HUMAN; LEUKOCYTE ANTIGEN;

ARTICLE; CAPILLARY ENDOTHELIAL CELL; CELL INTERACTION; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; COCULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; MESENCHYMAL STEM CELL; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; CELL CULTURE; CELL CULTURE TECHNIQUE; CELL LINEAGE; CYTOLOGY; DRUG EFFECTS; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; MESENCHYMAL STROMA CELL; METABOLISM; PERMEABILITY; VASCULAR ENDOTHELIUM;

ACTINS; ANTIGENS, CD; CADHERINS; CAVEOLIN 1; CELL CULTURE TECHNIQUES; CELL LINEAGE; CELLS, CULTURED; COCULTURE TECHNIQUES; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEPATOCYTE GROWTH FACTOR; HUMANS; LIPOPOLYSACCHARIDES; MESENCHYMAL STROMAL CELLS; OCCLUDIN; PARACRINE COMMUNICATION; PERMEABILITY;

EID: 84929104021     PISSN: None     EISSN: 17576512     Source Type: Journal    
DOI: 10.1186/s13287-015-0025-1     Document Type: Article

References (40)

1. Gonzales JN, Gorshkov B, Varn MN, Zemskova MA, Zemskov EA, Sridhar S, et al. Protective effect of adenosine receptors against lipopolysaccharide-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2014;306:L497-507.
2. Pittet JF, Mackersie RC, Martin TR, Matthay MA. Biological markers of acute lung injury: prognostic and pathogenetic significance. Am J Respir Crit Care Med. 1997;155:1187-205.
3. Mei SH, McCarter SD, Deng Y, Parker CH, Liles WC, Stewart DJ. Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1. PLoS Med. 2007;4:e269.
4. Lee JW, Fang X, Gupta N, Serikov V, Matthay MA. Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung. Proc Natl Acad Sci U S A. 2009;106:16357-62.
5. Song L, Xu J, Qu J, Sai Y, Chen C, Yu L, et al. A therapeutic role for mesenchymal stem cells in acute lung injury independent of hypoxiainduced mitogenic factor. J Cell Mol Med. 2012;16:376-85.
6. Sun J, Han ZB, Liao W, Yang SG, Yang Z, Yu J, et al. Intrapulmonary delivery of human umbilical cord mesenchymal stem cells attenuates acute lung injury by expanding CD4 + CD25+ Forkhead Boxp3 (FOXP3) + regulatory T cells and balancing anti-And pro-inflammatory factors. Cell Physiol Biochem. 2011;27:587-96.
7. Pati S, Matijevic N, Doursout MF, Ko T, Cao Y, Deng X, et al. Protective effects of fresh frozen plasma on vascular endothelial permeability, coagulation, and resuscitation after hemorrhagic shock are time dependent and diminish between days 0 and 5 after thaw. J Trauma. 2010;69:S55-63.
8. Goolaerts A, Pellan-Randrianarison N, Larghero J, Vanneaux V, Uzunhan Y, Gille T, et al. Conditioned media from mesenchymal stromal cells restore sodium transport and preserve epithelial permeability in an in vitro model of acute alveolar injury. Am J Physiol Lung Cell Mol Physiol. 2014;306:L975-85.
9. Lee JW, Gupta N, Serikov V, Matthay MA. Potential application of mesenchymal stem cells in acute lung injury. Expert Opin Biol Ther. 2009;9:1259-70.
10. Ding S, Merkulova-Rainon T, Han ZC, Tobelem G. HGF receptor upregulation contributes to the angiogenic phenotype of human endothelial cells and promotes angiogenesis in vitro. Blood. 2003;101:4816-22.
11. Katsha AM, Ohkouchi S, Xin H, Kanehira M, Sun R, Nukiwa T, et al. Paracrine factors of multipotent stromal cells ameliorate lung injury in an elastaseinduced emphysema model. Mol Ther. 2011;19:196-203.
12. Wang H, Yang YF, Zhao L, Xiao FJ, Zhang QW, Wen ML, et al. Hepatocyte growth factor gene-modified mesenchymal stem cells reduce radiationinduced lung injury. Hum Gene Ther. 2013;24:343-53.
13. Birukova AA, Cokic I, Moldobaeva N, Birukov KG. Paxillin is involved in the differential regulation of endothelial barrier by HGF and VEGF. Am J Respir Cell Mol Biol. 2009;40:99-107.
14. Chang CP, Chio CC, Cheong CU, Chao CM, Cheng BC, Lin MT. Hypoxic preconditioning enhances the therapeutic potential of the secretome from cultured human mesenchymal stem cells in experimental traumatic brain injury. Clin Sci. 2013;124:165-76.
15. Eom YW, Oh JE, Lee JI, Baik SK, Rhee KJ, Shin HC, et al. The role of growth factors in maintenance of stemness in bone marrow-derived mesenchymal stem cells. Biochem Biophys Res Commun. 2014;445:16-22.
16. Rosova I, Dao M, Capoccia B, Link D, Nolta JA. Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells. Stem Cells. 2008;26:2173-82.
17. Sassoli C, Pini A, Chellini F, Mazzanti B, Nistri S, Nosi D, et al. Bone marrow mesenchymal stromal cells stimulate skeletal myoblast proliferation through the paracrine release of VEGF. PLoS One. 2012;7:e37512.
18. Pati S, Khakoo AY, Zhao J, Jimenez F, Gerber MH, Harting M, et al. Human mesenchymal stem cells inhibit vascular permeability by modulating vascular endothelial cadherin/beta-catenin signaling. Stem Cells Dev. 2011;20:89-101.
19. Armstrong SM, Khajoee V, Wang C, Wang T, Tigdi J, Yin J, et al. Co-regulation of transcellular and paracellular leak across microvascular endothelium by dynamin and Rac. Am J Pathol. 2012;180:1308-23.
20. Xu J, Liu X, Chen J, Zacharek A, Cui X, Savant-Bhonsale S, et al. Cell-cell interaction promotes rat marrow stromal cell differentiation into endothelial cell via activation of TACE/TNF-Alpha signaling. Cell Transplant. 2010;19:43-53.
21. Vandenbroucke E, Mehta D, Minshall R, Malik AB. Regulation of endothelial junctional permeability. Ann N Y Acad Sci. 2008;1123:134-45.
22. Tuma P, Hubbard AL. Transcytosis: crossing cellular barriers. Physiol Rev. 2003;83:871-932.
23. Xiong G, Deng L, Zhu J, Rychahou PG, Xu R. Prolyl-4-hydroxylase alpha subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition. BMC Cancer. 2014;14:1.
24. Masterson C, Jerkic M, Curley GF, Laffey JG. Mesenchymal Stromal cell therapies-potential and pitfalls for ARDS. Minerva Anestesiol. 2015;81:179-94.
25. Komarova Y, Malik AB. Regulation of endothelial permeability via paracellular and transcellular transport pathways. Annu Rev Physiol. 2010;72:463-93.
26. Yang Z, Sun D, Yan Z, Reynolds AB, Christman JW, Minshall RD, et al. Differential Role for p120-Catenin in Regulation of TLR4 Signaling in Macrophages. J Immunol. 2014;193:1931-41.
27. Lee I, Dodia C, Chatterjee S, Feinstein SI, Fisher AB. Protection against LPS-induced acute lung injury by a mechanism-based inhibitor of NADPH oxidase (type 2). Am J Physiol Lung Cell Mol Physiol. 2014;306:L635-44.
28. Sohn SH, Jang H, Kim Y, Jang YP, Cho SH, Jung H, et al. The effects of Gamijinhae-Tang on elastase/lipopolysaccharide-induced lung inflammation in an animal model of acute lung injury. BMC Complement Altern Med. 2013;13:176.
29. Xiao H, Qin X, Ping D, Zuo K. Inhibition of Rho and Rac geranylgeranylation by atorvastatin is critical for preservation of endothelial junction integrity. PLoS One. 2013;8:e59233.
30. Aguirre A, Planell JA, Engel E. Dynamics of bone marrow-derived endothelial progenitor cell/mesenchymal stem cell interaction in co-culture and its implications in angiogenesis. Biochem Biophys Res Commun. 2010;400:284-91.
31. Lozito TP, Taboas JM, Kuo CK, Tuan RS. Mesenchymal stem cell modification of endothelial matrix regulates their vascular differentiation. J Cell Biochem. 2009;107:706-13.
32. Yamada N, Nakagawa S, Horai S, Tanaka K, Deli MA, Yatsuhashi H, et al. Hepatocyte growth factor enhances the barrier function in primary cultures of rat brain microvascular endothelial cells. Microvasc Res. 2014;92:41-9.
33. Birukova AA, Alekseeva E, Mikaelyan A, Birukov KG. HGF attenuates thrombin-induced endothelial permeability by Tiam1-mediated activation of the Rac pathway and by Tiam1/Rac-dependent inhibition of the Rho pathway. FASEB J. 2007;21:2776-86.
34. Birukova AA, Moldobaeva N, Xing J, Birukov KG. Magnitude-dependent effects of cyclic stretch on HGF-And VEGF-induced pulmonary endothelial remodeling and barrier regulation. Am J Physiol Lung Cell Mol Physiol. 2008;295:L612-23.
35. Zhang L, Himi T, Morita I, Murota S. Hepatocyte growth factor protects cultured rat cerebellar granule neurons from apoptosis via the phosphatidylinositol-3 kinase/Akt pathway. J Neurosci Res. 2000;59:489-96.
36. Rosen EM, Goldberg ID. Scatter factor and angiogenesis. Adv Cancer Res. 1995;67:257-79.
37. Jean C, Chen XL, Nam JO, Tancioni I, Uryu S, Lawson C, et al. Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function. J Cell Biol. 2014;204:247-63.
38. Chen W, Gassner B, Borner S, Nikolaev VO, Schlegel N, Waschke J, et al. Atrial natriuretic peptide enhances microvascular albumin permeability by the caveolae-mediated transcellular pathway. Cardiovasc Res. 2012;93:141-51.
39. Yang N, Liu YY, Pan CS, Sun K, Wei XH, Mao XW, et al. Pre-Treatment with andrographolide pills attenuates lipopolysaccharide-induced pulmonary microcirculatory disturbance and acute lung injury in rats. Microcirculation. 2014;21:703-16.
40. Zhang Y, Sun K, Liu YY, Zhang YP, Hu BH, Chang X, et al. Ginsenoside Rb1 ameliorates lipopolysaccharide-induced albumin leakage from rat mesenteric venules by intervening in both trans-And paracellular pathway. Am J Physiol Gastrointest Liver Physiol. 2014;306:G289-300.