Protection against LPS-induced acute lung injury by a mechanism-based inhibitor of NADPH oxidase (type 2)

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 306, Issue 7, 2014, Pages

  Lee, Intae ^a   Dodia, Chandra ^a   Chatterjee, Shampa ^a   Feinstein, Sheldon I ^a   Fisher, Aron B ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Lipid peroxidation; Lung permeability; Protein oxidation; Reactive oxygen species; Transition state inhibitor

Indexed keywords

1 HEXADECYL 3 (TRIFLUOROETHYL) SN GLYCERO 2 PHOSPHOMETHANOL; CXCL3 CHEMOKINE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; INTERLEUKIN 6; MJ 33; OXIDOREDUCTASE INHIBITOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2 INHIBITOR; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG MECHANISM; INFLAMMATORY CELL; LIPID PEROXIDATION; LUNG INFILTRATE; LUNG LAVAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

LIPID PEROXIDATION; LUNG PERMEABILITY; PHOSPHOLIPASE A2; PROTEIN OXIDATION; REACTIVE OXYGEN SPECIES; TRANSITION STATE INHIBITOR;

ACUTE LUNG INJURY; ANIMALS; CHEMOKINES; CYTOKINES; GLYCEROPHOSPHATES; LIPOPOLYSACCHARIDES; LUNG; MICE; NADPH OXIDASE; NF-KAPPA B; PEROXIREDOXIN VI; REACTIVE OXYGEN SPECIES; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84900547292     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00374.2013     Document Type: Article

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