메뉴 건너뛰기




Volumn 6, Issue , 2015, Pages

Galanin modulates the neural niche to favour perineural invasion in head and neck cancer

Author keywords

[No Author keywords available]

Indexed keywords

CALCITONIN; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 2; GALANIN; NEUROTROPHIN 4; PROSTAGLANDIN E2; TACHYKININ; UNCLASSIFIED DRUG; GALANIN RECEPTOR 2; TRANSCRIPTION FACTOR NFAT;

EID: 84929103846     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7885     Document Type: Article
Times cited : (74)

References (66)
  • 1
    • 68149170070 scopus 로고    scopus 로고
    • Perineural invasion in cancer: A review of the literature
    • Liebig, C., Ayala, G., Wilks, J. A., Berger, D. H. & Albo, D. Perineural invasion in cancer: a review of the literature. Cancer 115, 3379-3391 (2009).
    • (2009) Cancer , vol.115 , pp. 3379-3391
    • Liebig, C.1    Ayala, G.2    Wilks, J.A.3    Berger, D.H.4    Albo, D.5
  • 2
    • 80054801121 scopus 로고    scopus 로고
    • Perineural invasion in oral squamous cell carcinoma: A discussion of significance and review of the literature
    • Binmadi, N. O. & Basile, J. R. Perineural invasion in oral squamous cell carcinoma: a discussion of significance and review of the literature. Oral Oncol. 47, 1005-1010 (2011).
    • (2011) Oral Oncol , vol.47 , pp. 1005-1010
    • Binmadi, N.O.1    Basile, J.R.2
  • 3
    • 0035157891 scopus 로고    scopus 로고
    • In vitro dorsal root ganglia and human prostate cell line interaction: Redefining perineural invasion in prostate cancer
    • Ayala, G. E. et al. In vitro dorsal root ganglia and human prostate cell line interaction: redefining perineural invasion in prostate cancer. Prostate 49, 213-223 (2001).
    • (2001) Prostate , vol.49 , pp. 213-223
    • Ayala, G.E.1
  • 4
    • 80053162486 scopus 로고    scopus 로고
    • Perineural invasion and associated pain in pancreatic cancer
    • Bapat, A. A., Hostetter, G., Von Hoff, D. D. & Han, H. Perineural invasion and associated pain in pancreatic cancer. Nat. Rev. Cancer 11, 695-707 (2011).
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 695-707
    • Bapat, A.A.1    Hostetter, G.2    Von Hoff, D.D.3    Han, H.4
  • 5
    • 84863276641 scopus 로고    scopus 로고
    • Perineural invasion and spread in head and neck cancer
    • Johnston, M., Yu, E. & Kim, J. Perineural invasion and spread in head and neck cancer. Expert Rev. Anticancer Ther. 12, 359-371 (2012).
    • (2012) Expert Rev. Anticancer Ther , vol.12 , pp. 359-371
    • Johnston, M.1    Yu, E.2    Kim, J.3
  • 6
    • 34548022639 scopus 로고    scopus 로고
    • Gene expression profile of salivary adenoid cystic carcinoma associated with perineural invasion
    • Chen, W. et al. Gene expression profile of salivary adenoid cystic carcinoma associated with perineural invasion. Tohoku J. Exp. Med. 212, 319-334 (2007).
    • (2007) Tohoku J. Exp. Med , vol.212 , pp. 319-334
    • Chen, W.1
  • 7
    • 79954419567 scopus 로고    scopus 로고
    • Rap1 mediates galanin receptor 2-induced proliferation and survival in squamous cell carcinoma
    • Banerjee, R., Henson, B. S., Russo, N., Tsodikov, A. & D'Silva, N. J. Rap1 mediates galanin receptor 2-induced proliferation and survival in squamous cell carcinoma. Cell Signal. 23, 1110-1118 (2011).
    • (2011) Cell Signal , vol.23 , pp. 1110-1118
    • Banerjee, R.1    Henson, B.S.2    Russo, N.3    Tsodikov, A.4    D'Silva, N.J.5
  • 8
    • 59949102128 scopus 로고    scopus 로고
    • The galanin signaling cascade is a candidate pathway regulating oncogenesis in human squamous cell carcinoma
    • Sugimoto, T. et al. The galanin signaling cascade is a candidate pathway regulating oncogenesis in human squamous cell carcinoma. Genes Chromosomes Cancer 48, 132-142 (2009).
    • (2009) Genes Chromosomes Cancer , vol.48 , pp. 132-142
    • Sugimoto, T.1
  • 10
    • 84878752709 scopus 로고    scopus 로고
    • The histone methyltransferase ezh2 mediates tumor progression on the chick chorioallantoic membrane assay, a novel model of head and neck squamous cell carcinoma
    • Liu, M. et al. The histone methyltransferase EZH2 mediates tumor progression on the chick chorioallantoic membrane assay, a novel model of head and neck squamous cell carcinoma. Transl. Oncol. 6, 273-281 (2013).
    • (2013) Transl. Oncol , vol.6 , pp. 273-281
    • Liu, M.1
  • 11
    • 0035260265 scopus 로고    scopus 로고
    • The role of galanin as a multi-functional neuropeptide in the nervous system
    • Wynick, D., Thompson, S. W. & McMahon, S. B. The role of galanin as a multi-functional neuropeptide in the nervous system. Curr. Opin. Pharmacol. 1, 73-77 (2001).
    • (2001) Curr. Opin. Pharmacol , vol.1 , pp. 73-77
    • Wynick, D.1    Thompson, S.W.2    McMahon, S.B.3
  • 12
    • 20744447187 scopus 로고    scopus 로고
    • Galanin receptor 1 has anti-proliferative effects in oral squamous cell carcinoma
    • Henson, B. S. et al. Galanin receptor 1 has anti-proliferative effects in oral squamous cell carcinoma. J. Biol. Chem. 280, 22564-22571 (2005).
    • (2005) J. Biol. Chem , vol.280 , pp. 22564-22571
    • Henson, B.S.1
  • 13
    • 79959772797 scopus 로고    scopus 로고
    • Emerging roles of canonical trp channels in neuronal function
    • Bollimuntha, S., Selvaraj, S. & Singh, B. B. Emerging roles of canonical TRP channels in neuronal function. Adv. Exp. Med. Biol. 704, 573-593 (2011).
    • (2011) Adv. Exp. Med. Biol , vol.704 , pp. 573-593
    • Bollimuntha, S.1    Selvaraj, S.2    Singh, B.B.3
  • 14
    • 77956175013 scopus 로고    scopus 로고
    • Nfat immunity and cancer: A transcription factor comes of age
    • Muller, M. R. & Rao, A. NFAT, immunity and cancer: a transcription factor comes of age. Nat. Rev. Immunol. 10, 645-656 (2010).
    • (2010) Nat. Rev. Immunol , vol.10 , pp. 645-656
    • Muller, M.R.1    Rao, A.2
  • 15
    • 84865798525 scopus 로고    scopus 로고
    • Transcription factor nfatc2 controls the emergence of colon cancer associated with il-6-dependent colitis
    • Gerlach, K. et al. Transcription factor NFATc2 controls the emergence of colon cancer associated with IL-6-dependent colitis. Cancer Res. 72, 4340-4350 (2012).
    • (2012) Cancer Res , vol.72 , pp. 4340-4350
    • Gerlach, K.1
  • 16
    • 0034788198 scopus 로고    scopus 로고
    • Expression of inflammatory modulator cox-2 in pancreatic ductal adenocarcinoma and its relationship to pathologic and clinical parameters
    • Merati, K. et al. Expression of inflammatory modulator COX-2 in pancreatic ductal adenocarcinoma and its relationship to pathologic and clinical parameters. Am. J. Clin. Oncol. 24, 447-452 (2001).
    • (2001) Am. J. Clin. Oncol , vol.24 , pp. 447-452
    • Merati, K.1
  • 17
    • 84874438110 scopus 로고    scopus 로고
    • Role of the nervous system in cancer metastasis
    • Li, S., Sun, Y. & Gao, D. Role of the nervous system in cancer metastasis. Oncol. Lett. 5, 1101-1111 (2013).
    • (2013) Oncol. Lett , vol.5 , pp. 1101-1111
    • Li, S.1    Sun, Y.2    Gao, D.3
  • 18
    • 33847364415 scopus 로고    scopus 로고
    • The neuro-neoplastic synapse: Does it exist?
    • Zanker, K. S. The neuro-neoplastic synapse: does it exist? Prog. Exp. Tumor Res. 39, 154-161 (2007).
    • (2007) Prog. Exp. Tumor Res , vol.39 , pp. 154-161
    • Zanker, K.S.1
  • 19
    • 77952287809 scopus 로고    scopus 로고
    • Nerve growth factor and tyrosine kinase a receptor in oral squamous cell carcinoma: Is there an association with perineural invasion?
    • Kolokythas, A., Cox, D. P., Dekker, N. & Schmidt, B. L. Nerve growth factor and tyrosine kinase A receptor in oral squamous cell carcinoma: is there an association with perineural invasion? J. Oral Maxillofac. Surg. 68, 1290-1295 (2010).
    • (2010) J. Oral Maxillofac. Surg , vol.68 , pp. 1290-1295
    • Kolokythas, A.1    Cox, D.P.2    Dekker, N.3    Schmidt, B.L.4
  • 20
    • 84863116555 scopus 로고    scopus 로고
    • Plexin-b1 and semaphorin 4d cooperate to promote perineural invasion in a rhoa/rok-dependent manner
    • Binmadi, N. O. et al. Plexin-B1 and semaphorin 4D cooperate to promote perineural invasion in a RhoA/ROK-dependent manner. Am. J. Pathol. 180, 1232-1242 (2012).
    • (2012) Am. J. Pathol , vol.180 , pp. 1232-1242
    • Binmadi, N.O.1
  • 21
    • 0035205898 scopus 로고    scopus 로고
    • Tumor deposition of laminin-5 and the relationship with perineural invasion
    • Anderson, T. D., Feldman, M., Weber, R. S., Ziober, A. F. & Ziober, B. L. Tumor deposition of laminin-5 and the relationship with perineural invasion. Laryngoscope 111, 2140-2143 (2001).
    • (2001) Laryngoscope , vol.111 , pp. 2140-2143
    • Anderson, T.D.1    Feldman, M.2    Weber, R.S.3    Ziober, A.F.4    Ziober, B.L.5
  • 22
    • 79952255166 scopus 로고    scopus 로고
    • The galanin system in cancer
    • Rauch, I. & Kofler, B. The galanin system in cancer. EXS 102, 223-241 (2010).
    • (2010) EXS , vol.102 , pp. 223-241
    • Rauch, I.1    Kofler, B.2
  • 23
    • 0034633760 scopus 로고    scopus 로고
    • Galanin regulates the postnatal survival of a subset of basal forebrain cholinergic neurons
    • O'Meara, G. et al. Galanin regulates the postnatal survival of a subset of basal forebrain cholinergic neurons. Proc. Natl Acad. Sci. USA 97, 11569-11574 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 11569-11574
    • O'Meara, G.1
  • 24
    • 44849115066 scopus 로고    scopus 로고
    • Selective stimulation of galr1 and galr2 in rat substantia gelatinosa reveals a cellular basis for the anti-and pro-nociceptive actions of galanin
    • Alier, K. A., Chen, Y., Sollenberg, U. E., Langel, U. & Smith, P. A. Selective stimulation of GalR1 and GalR2 in rat substantia gelatinosa reveals a cellular basis for the anti-and pro-nociceptive actions of galanin. Pain 137, 138-146 (2008).
    • (2008) Pain , vol.137 , pp. 138-146
    • Alier, K.A.1    Chen, Y.2    Sollenberg, U.E.3    Langel, U.4    Smith, P.A.5
  • 25
    • 0031785205 scopus 로고    scopus 로고
    • Inducible galanin and galr2 receptor system in motor neuron injury and regeneration
    • Burazin, T. C. & Gundlach, A. L. Inducible galanin and GalR2 receptor system in motor neuron injury and regeneration. J. Neurochem. 71, 879-882 (1998).
    • (1998) J. Neurochem , vol.71 , pp. 879-882
    • Burazin, T.C.1    Gundlach, A.L.2
  • 26
    • 2342504654 scopus 로고    scopus 로고
    • Expression of neuropeptide galanin and galanin receptors in human skin
    • Kofler, B. et al. Expression of neuropeptide galanin and galanin receptors in human skin. J. Invest. Dermatol. 122, 1050-1053 (2004).
    • (2004) J. Invest. Dermatol , vol.122 , pp. 1050-1053
    • Kofler, B.1
  • 27
    • 79952256597 scopus 로고    scopus 로고
    • Galanin family of peptides in skin function
    • Bauer, J. W., Lang, R., Jakab, M. & Kofler, B. Galanin family of peptides in skin function. EXS 102, 51-59 (2010).
    • (2010) EXS , vol.102 , pp. 51-59
    • Bauer, J.W.1    Lang, R.2    Jakab, M.3    Kofler, B.4
  • 28
    • 0344898855 scopus 로고    scopus 로고
    • Transgenic mice over-expressing galanin exhibit pituitary adenomas and increased secretion of galanin, prolactin and growth hormone
    • Perumal, P. & Vrontakis, M. E. Transgenic mice over-expressing galanin exhibit pituitary adenomas and increased secretion of galanin, prolactin and growth hormone. J. Endocrinol. 179, 145-154 (2003).
    • (2003) J. Endocrinol , vol.179 , pp. 145-154
    • Perumal, P.1    Vrontakis, M.E.2
  • 29
    • 79953892288 scopus 로고    scopus 로고
    • Galr2/3 mediates proliferative and trophic effects of galanin on postnatal hippocampal precursors
    • Abbosh, C., Lawkowski, A., Zaben, M. & Gray, W. GalR2/3 mediates proliferative and trophic effects of galanin on postnatal hippocampal precursors. J. Neurochem. 117, 425-436 (2011).
    • (2011) J. Neurochem , vol.117 , pp. 425-436
    • Abbosh, C.1    Lawkowski, A.2    Zaben, M.3    Gray, W.4
  • 30
    • 59449094364 scopus 로고    scopus 로고
    • Epigenetic inactivation of galanin receptor 1 in head and neck cancer
    • Misawa, K. et al. Epigenetic inactivation of galanin receptor 1 in head and neck cancer. Clin. Cancer Res. 14, 7604-7613 (2008).
    • (2008) Clin. Cancer Res , vol.14 , pp. 7604-7613
    • Misawa, K.1
  • 31
    • 4143126537 scopus 로고    scopus 로고
    • Loss of chromosome arm 18q with tumor progression in head and neck squamous cancer
    • Takebayashi, S. et al. Loss of chromosome arm 18q with tumor progression in head and neck squamous cancer. Genes Chromosomes Cancer 41, 145-154 (2004).
    • (2004) Genes Chromosomes Cancer , vol.41 , pp. 145-154
    • Takebayashi, S.1
  • 32
    • 77956480098 scopus 로고    scopus 로고
    • Tumor interactions with soluble factors and the nervous system
    • Voss, M. J. & Entschladen, F. Tumor interactions with soluble factors and the nervous system. Cell Commun. Signal. 8, 21 (2010).
    • (2010) Cell Commun. Signal , vol.8 , pp. 21
    • Voss, M.J.1    Entschladen, F.2
  • 33
    • 1642325724 scopus 로고    scopus 로고
    • Tumour-cell migration, invasion, and metastasis: Navigation by neurotransmitters
    • Entschladen, F., Drell, T. L. t., Lang, K., Joseph, J. & Zaenker, K. S. Tumour-cell migration, invasion, and metastasis: navigation by neurotransmitters. Lancet Oncol. 5, 254-258 (2004).
    • (2004) Lancet Oncol , vol.5 , pp. 254-258
    • Entschladen, F.1    Drell, T.L.T.2    Lang, K.3    Joseph, J.4    Zaenker, K.S.5
  • 34
    • 79955091053 scopus 로고    scopus 로고
    • Activation of the galanin receptor 2 in the periphery reverses nerve injury-induced allodynia
    • Hulse, R. P.,Wynick, D. & Donaldson, L. F. Activation of the galanin receptor 2 in the periphery reverses nerve injury-induced allodynia. Mol. Pain 7, 26 (2011).
    • (2011) Mol. Pain , vol.7 , pp. 26
    • Hulse, R.P.1    Wynick, D.2    Donaldson, L.F.3
  • 35
    • 78650799038 scopus 로고    scopus 로고
    • The galanin peptide family in inflammation
    • Lang, R. & Kofler, B. The galanin peptide family in inflammation. Neuropeptides 45, 1-8 (2011).
    • (2011) Neuropeptides , vol.45 , pp. 1-8
    • Lang, R.1    Kofler, B.2
  • 36
    • 79952262410 scopus 로고    scopus 로고
    • Galanin acts as a trophic factor to the central and peripheral nervous systems
    • Hobson, S. A. et al. Galanin acts as a trophic factor to the central and peripheral nervous systems. EXS 102, 25-38 (2010).
    • (2010) EXS , vol.102 , pp. 25-38
    • Hobson, S.A.1
  • 37
    • 33646568470 scopus 로고    scopus 로고
    • Differential distribution and regulation of galanin receptors-1 and-2 in the rat lumbar spinal cord
    • Brumovsky, P., Mennicken, F., O'Donnell, D. & Hokfelt, T. Differential distribution and regulation of galanin receptors-1 and-2 in the rat lumbar spinal cord. Brain Res. 1085, 111-120 (2006).
    • (2006) Brain Res , vol.1085 , pp. 111-120
    • Brumovsky, P.1    Mennicken, F.2    O'Donnell, D.3    Hokfelt, T.4
  • 38
    • 0032052177 scopus 로고    scopus 로고
    • Up-regulation of gdnfr-alpha and c-ret mrna in facial motor neurons following facial nerve injury in the rat
    • Burazin, T. C. & Gundlach, A. L. Up-regulation of GDNFR-alpha and c-ret mRNA in facial motor neurons following facial nerve injury in the rat. Brain Res. Mol. Brain Res. 55, 331-336 (1998).
    • (1998) Brain Res. Mol. Brain Res , vol.55 , pp. 331-336
    • Burazin, T.C.1    Gundlach, A.L.2
  • 39
    • 84255204907 scopus 로고    scopus 로고
    • Infiltrating lymphocytes and human papillomavirus-16-associated oropharyngeal cancer
    • Wansom, D. et al. Infiltrating lymphocytes and human papillomavirus-16-associated oropharyngeal cancer. Laryngoscope 122, 121-127 (2012).
    • (2012) Laryngoscope , vol.122 , pp. 121-127
    • Wansom, D.1
  • 40
    • 77649185062 scopus 로고    scopus 로고
    • Molecular mechanisms of perineural invasion, a forgotten pathway of dissemination and metastasis
    • Marchesi, F., Piemonti, L., Mantovani, A. & Allavena, P. Molecular mechanisms of perineural invasion, a forgotten pathway of dissemination and metastasis. Cytokine Growth Factor Rev. 21, 77-82 (2010).
    • (2010) Cytokine Growth Factor Rev , vol.21 , pp. 77-82
    • Marchesi, F.1    Piemonti, L.2    Mantovani, A.3    Allavena, P.4
  • 41
    • 59449089708 scopus 로고    scopus 로고
    • Cancer-related axonogenesis and neurogenesis in prostate cancer
    • Ayala, G. E. et al. Cancer-related axonogenesis and neurogenesis in prostate cancer. Clin. Cancer Res. 14, 7593-7603 (2008).
    • (2008) Clin. Cancer Res , vol.14 , pp. 7593-7603
    • Ayala, G.E.1
  • 42
    • 84869237693 scopus 로고    scopus 로고
    • Endoneurial macrophages induce perineural invasion of pancreatic cancer cells by secretion of gdnf and activation of ret tyrosine kinase receptor
    • Cavel, O. et al. Endoneurial macrophages induce perineural invasion of pancreatic cancer cells by secretion of GDNF and activation of RET tyrosine kinase receptor. Cancer Res. 72, 5733-5743 (2012).
    • (2012) Cancer Res , vol.72 , pp. 5733-5743
    • Cavel, O.1
  • 43
    • 84880279713 scopus 로고    scopus 로고
    • Autonomic nerve development contributes to prostate cancer progression
    • Magnon, C. et al. Autonomic nerve development contributes to prostate cancer progression. Science 341, 1236361 (2013).
    • (2013) Science , vol.341 , pp. 1236361
    • Magnon, C.1
  • 44
    • 84885612989 scopus 로고    scopus 로고
    • Dear1 is a chromosome 1p35 tumor suppressor and master regulator of tgf-beta-driven epithelial-mesenchymal transition
    • Chen, N. et al. DEAR1 is a chromosome 1p35 tumor suppressor and master regulator of TGF-beta-driven epithelial-mesenchymal transition. Cancer Discov. 3, 1172-1189 (2013).
    • (2013) Cancer Discov , vol.3 , pp. 1172-1189
    • Chen, N.1
  • 45
    • 84872416422 scopus 로고    scopus 로고
    • Biomarkers of epithelial-mesenchymal transition in squamous cell carcinoma
    • Scanlon, C. S., Van Tubergen, E. A., Inglehart, R. C. & D'Silva, N. J. Biomarkers of epithelial-mesenchymal transition in squamous cell carcinoma. J. Dent. Res. 92, 114-121 (2013).
    • (2013) J. Dent. Res , vol.92 , pp. 114-121
    • Scanlon, C.S.1    Van Tubergen, E.A.2    Inglehart, R.C.3    D'Silva, N.J.4
  • 46
    • 84863704553 scopus 로고    scopus 로고
    • Suppression of tumor invasion and metastasis by concurrent inhibition of c-met and vegf signaling in pancreatic neuroendocrine tumors
    • Sennino, B. et al. Suppression of tumor invasion and metastasis by concurrent inhibition of c-Met and VEGF signaling in pancreatic neuroendocrine tumors. Cancer Discov. 2, 270-287 (2012).
    • (2012) Cancer Discov , vol.2 , pp. 270-287
    • Sennino, B.1
  • 47
    • 0034633771 scopus 로고    scopus 로고
    • Targeted disruption of the galanin gene reduces the number of sensory neurons and their regenerative capacity
    • Holmes, F. E. et al. Targeted disruption of the galanin gene reduces the number of sensory neurons and their regenerative capacity. Proc. Natl Acad. Sci. USA 97, 11563-11568 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 11563-11568
    • Holmes, F.E.1
  • 48
    • 18944378748 scopus 로고    scopus 로고
    • Phenotypic analysis of mice deficient in the type 2 galanin receptor (galr2)
    • Gottsch, M. L. et al. Phenotypic analysis of mice deficient in the type 2 galanin receptor (GALR2). Mol. Cell. Biol. 25, 4804-4811 (2005).
    • (2005) Mol. Cell. Biol , vol.25 , pp. 4804-4811
    • Gottsch, M.L.1
  • 49
    • 33750048437 scopus 로고    scopus 로고
    • Mice deficient for galanin receptor 2 have decreased neurite outgrowth from adult sensory neurons and impaired pain-like behaviour
    • Hobson, S. A., Holmes, F. E., Kerr, N. C., Pope, R. J. & Wynick, D. Mice deficient for galanin receptor 2 have decreased neurite outgrowth from adult sensory neurons and impaired pain-like behaviour. J. Neurochem. 99, 1000-1010 (2006).
    • (2006) J. Neurochem , vol.99 , pp. 1000-1010
    • Hobson, S.A.1    Holmes, F.E.2    Kerr, N.C.3    Pope, R.J.4    Wynick, D.5
  • 50
    • 70350514636 scopus 로고    scopus 로고
    • Nfat proteins: Emerging roles in cancer progression
    • Mancini, M. & Toker, A. NFAT proteins: emerging roles in cancer progression. Nat. Rev. Cancer 9, 810-820 (2009).
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 810-820
    • Mancini, M.1    Toker, A.2
  • 51
    • 84899798198 scopus 로고    scopus 로고
    • The g protein-coupled receptor galr2 promotes angiogenesis in head and neck cancer
    • Banerjee, R. et al. The G protein-coupled receptor GALR2 promotes angiogenesis in head and neck cancer. Mol. Cancer Ther. 13, 1323-1333 (2014).
    • (2014) Mol. Cancer Ther , vol.13 , pp. 1323-1333
    • Banerjee, R.1
  • 52
    • 40649089094 scopus 로고    scopus 로고
    • Galanin decreases proliferation of pc12 cells and induces apoptosis via its subtype 2 receptor (galr2)
    • Tofighi, R. et al. Galanin decreases proliferation of PC12 cells and induces apoptosis via its subtype 2 receptor (GalR2). Proc. Natl Acad. Sci. USA 105, 2717-2722 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 2717-2722
    • Tofighi, R.1
  • 53
    • 0028990801 scopus 로고
    • Direct demonstration of nfatp dephosphorylation and nuclear localization in activated ht-2 cells using a specific nfatp polyclonal antibody
    • Ruff, V. A. & Leach, K. L. Direct demonstration of NFATp dephosphorylation and nuclear localization in activated HT-2 cells using a specific NFATp polyclonal antibody. J. Biol. Chem. 270, 22602-22607 (1995).
    • (1995) J. Biol. Chem , vol.270 , pp. 22602-22607
    • Ruff, V.A.1    Leach, K.L.2
  • 54
    • 24944543400 scopus 로고    scopus 로고
    • Lymph node metastases from cutaneous squamous cell carcinoma of the head and neck
    • Moore, B. A. et al. Lymph node metastases from cutaneous squamous cell carcinoma of the head and neck. Laryngoscope 115, 1561-1567 (2005).
    • (2005) Laryngoscope , vol.115 , pp. 1561-1567
    • Moore, B.A.1
  • 55
    • 84924152287 scopus 로고    scopus 로고
    • Histopathological features of clinical perineural invasion of cutaneous squamous cell carcinoma of the head and neck and the potential implications for treatment
    • Panizza, B. et al. Histopathological features of clinical perineural invasion of cutaneous squamous cell carcinoma of the head and neck and the potential implications for treatment. Head Neck 36, 1611-1618 (2014).
    • (2014) Head Neck , vol.36 , pp. 1611-1618
    • Panizza, B.1
  • 56
    • 84879604987 scopus 로고    scopus 로고
    • Perineural invasion of head and neck skin cancer: Diagnostic and therapeutic implications
    • Panizza, B. & Warren, T. Perineural invasion of head and neck skin cancer: diagnostic and therapeutic implications. Curr. Oncol. Rep. 15, 128-133 (2013).
    • (2013) Curr. Oncol. Rep , vol.15 , pp. 128-133
    • Panizza, B.1    Warren, T.2
  • 57
    • 35848959463 scopus 로고    scopus 로고
    • Engineering tumors with 3d scaffolds
    • Fischbach, C. et al. Engineering tumors with 3D scaffolds. Nat. Methods 4, 855-860 (2007).
    • (2007) Nat. Methods , vol.4 , pp. 855-860
    • Fischbach, C.1
  • 58
    • 0029982831 scopus 로고    scopus 로고
    • Retinoic acid induces cells cultured from oral squamous cell carcinomas to become anti-angiogenic
    • Lingen, M. W., Polverini, P. J. & Bouck, N. P. Retinoic acid induces cells cultured from oral squamous cell carcinomas to become anti-angiogenic. Am. J. Pathol. 149, 247-258 (1996).
    • (1996) Am. J. Pathol , vol.149 , pp. 247-258
    • Lingen, M.W.1    Polverini, P.J.2    Bouck, N.P.3
  • 59
    • 77949400528 scopus 로고    scopus 로고
    • Genotyping of 73 um-scc head and neck squamous cell carcinoma cell lines
    • Brenner, J. C. et al. Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines. Head Neck 32, 417-426 (2010).
    • (2010) Head Neck , vol.32 , pp. 417-426
    • Brenner, J.C.1
  • 60
    • 84875169465 scopus 로고    scopus 로고
    • Rab25 regulates invasion and metastasis in head and neck cancer
    • Amornphimoltham, P. et al. Rab25 regulates invasion and metastasis in head and neck cancer. Clin. Cancer Res. 19, 1375-1388 (2013).
    • (2013) Clin. Cancer Res , vol.19 , pp. 1375-1388
    • Amornphimoltham, P.1
  • 61
    • 80054940941 scopus 로고    scopus 로고
    • The tumor suppressor gene rap1gap is silenced by mir-101-mediated ezh2 overexpression in invasive squamous cell carcinoma
    • Banerjee, R. et al. The tumor suppressor gene rap1GAP is silenced by miR-101-mediated EZH2 overexpression in invasive squamous cell carcinoma. Oncogene 30, 4339-4349 (2011).
    • (2011) Oncogene , vol.30 , pp. 4339-4349
    • Banerjee, R.1
  • 62
    • 84905460114 scopus 로고    scopus 로고
    • Trip13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer
    • Banerjee, R. et al. TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer. Nat. Commun. 5, 4527 (2014).
    • (2014) Nat. Commun , vol.5 , pp. 4527
    • Banerjee, R.1
  • 63
    • 0032799753 scopus 로고    scopus 로고
    • Glycosylation of g-protein-coupled receptors for hormones central to normal reproductive functioning: Its occurrence and role
    • Wheatley, M. & Hawtin, S. R. Glycosylation of G-protein-coupled receptors for hormones central to normal reproductive functioning: its occurrence and role. Hum. Reprod. Update 5, 356-364 (1999).
    • (1999) Hum. Reprod. Update , vol.5 , pp. 356-364
    • Wheatley, M.1    Hawtin, S.R.2
  • 64
    • 73949087260 scopus 로고    scopus 로고
    • Induction of a mt1-mmp and mt2-mmp-dependent basement membrane transmigration program in cancer cells by snail1
    • Ota, I., Li, X. Y., Hu, Y. & Weiss, S. J. Induction of a MT1-MMP and MT2-MMP-dependent basement membrane transmigration program in cancer cells by Snail1. Proc. Natl Acad. Sci. USA 106, 20318-20323 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 20318-20323
    • Ota, I.1    Li, X.Y.2    Hu, Y.3    Weiss, S.J.4
  • 66
    • 32644475906 scopus 로고    scopus 로고
    • Histopathological prognosticators in oral and oropharyngeal squamous cell carcinoma
    • Woolgar, J. A. Histopathological prognosticators in oral and oropharyngeal squamous cell carcinoma. Oral Oncol. 42, 229-239 (2006).
    • (2006) Oral Oncol , vol.42 , pp. 229-239
    • Woolgar, J.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.