Dear1 is a chromosome 1p35 tumor suppressor and master regulator of TGF-β-driven epithelial-mesenchymal transition

Cancer Discovery

Volumn 3, Issue 10, 2013, Pages 1172-1189

  Chen, Nanyue ^a   Balasenthil, Seetharaman ^a   Reuther, Jacquelyn ^a,b   Frayna, Aileen ^a   Wang, Ying ^a   Chandler, Dawn S ^a   Abruzzo, Lynne V ^a   Rashid, Asif ^a   Rodriguez, Jaime ^a   Lozano, Guillermina ^a   Cao, Yu ^a   Lokken, Erica ^a   Chen, Jinyun ^a   Frazier, Marsha L ^a   Sahin, Aysegul A ^a   Wistuba, Ignacio I ^a,b   Sen, Subrata ^a   Lott, Steven T ^a   Killary, Ann McNeill ^a,b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CASPASE 3; HYBRID PROTEIN; NERVE CELL ADHESION MOLECULE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN INHIBITOR; SMAD3 INHIBITOR; SMAD3 PROTEIN; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VIMENTIN;

ADENOCARCINOMA; ANIMAL MODEL; ANIMAL TISSUE; ANOIKIS; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DEAR1 GENE; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR INVASION; TUMOR SUPPRESSOR GENE; UBIQUITINATION; UPREGULATION; WESTERN BLOTTING; WOUND HEALING;

ANIMALS; CELL LINE, TUMOR; CHROMOSOMES, HUMAN, PAIR 1; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HELA CELLS; HUMANS; MCF-7 CELLS; MICE; PROGNOSIS; RECEPTORS, ANGIOTENSIN; RECEPTORS, ENDOTHELIN; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEINS; UBIQUITINATION;

EID: 84885612989     PISSN: 21598274     EISSN: 21598290     Source Type: Journal    
DOI: 10.1158/2159-8290.CD-12-0499     Document Type: Article

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