Formation and Implications of Alpha-Synuclein Radical in Maneb- and Paraquat-Induced Models of Parkinson’s Disease

Molecular Neurobiology

Volumn 53, Issue 5, 2016, Pages 2983-2994

  Kumar, Ashutosh ^a   Leinisch, Fabian ^a   Kadiiska, Maria B ^a   Corbett, Jean ^a   Mason, Ronald P ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

DMPO; Immuno spin trapping; Parkinson s disease; Peroxynitrite; Protein radicals

Indexed keywords

ALPHA SYNUCLEIN; ALPHA SYNUCLEIN RADICAL; FREE RADICAL; INDUCIBLE NITRIC OXIDE SYNTHASE; MANEB; PARAQUAT; PEROXYNITRITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG; 5,5-DIMETHYL-1-PYRROLINE-1-OXIDE; AMINE OXIDE; PEROXYNITROUS ACID; SPIN LABEL; TYROSINE 3 MONOOXYGENASE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL PROCEDURES; CONTROLLED STUDY; DISEASE COURSE; DOPAMINERGIC NERVE CELL; ENZYME ACTIVATION; GLIOSIS; IMMUNOPRECIPITATION; IMMUNOSPIN TRAPPING; KNOCKOUT MOUSE; MALE; MESENCEPHALON; MOUSE; NONHUMAN; PARKINSON DISEASE; PROTEIN AGGREGATION; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; DISEASE MODEL; INTRAPERITONEAL DRUG ADMINISTRATION; METABOLISM; MICROGLIA; PATHOLOGY; SUBSTANTIA NIGRA;

ALPHA-SYNUCLEIN; ANIMALS; CYCLIC N-OXIDES; DISEASE MODELS, ANIMAL; DOPAMINERGIC NEURONS; INJECTIONS, INTRAPERITONEAL; MALE; MANEB; MESENCEPHALON; MICE, INBRED C57BL; MICROGLIA; MODELS, BIOLOGICAL; NADPH OXIDASES; NITRIC OXIDE SYNTHASE TYPE II; PARAQUAT; PARKINSON DISEASE; PEROXYNITROUS ACID; SPIN LABELS; SUBSTANTIA NIGRA; TYROSINE 3-MONOOXYGENASE;

EID: 84929094701     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9179-1     Document Type: Article

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