Prolonged fasting identifies heat shock protein 10 as a sirtuin 3 substrate: Elucidating a new mechanism linking mitochondrial protein acetylation to fatty acid oxidation enzyme folding and function

Journal of Biological Chemistry

Volumn 290, Issue 4, 2015, Pages 2466-2476

  Lu, Zhongping ^a,b,c   Chen, Yong ^a   Aponte, Angel M ^a   Battaglia, Valentina ^b,c   Gucek, Marjan ^a   Sack, Michael N ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; AMINO ACIDS; CHAINS; ENZYMES; NUTRIENTS; OXIDATION; PROTEIN FOLDING; PROTEINS;

FAT OXIDATION; FATTY ACID OXIDATION; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 10; MEDIUM-CHAIN ACYL-COA DEHYDROGENASE; METABOLIC FUNCTION; MITOCHONDRIAL PROTEIN; NEW MECHANISMS;

FATTY ACIDS;

ACYL COENZYME A DEHYDROGENASE; CHAPERONIN 60; EARLY PREGNANCY FACTOR; LYSINE; MITOCHONDRIAL PROTEIN; SIRTUIN 2; CHAPERONE; FATTY ACID; OXYGEN; REACTIVE OXYGEN METABOLITE; SIRT3 PROTEIN, MOUSE; SIRTUIN 3;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; FATTY ACID OXIDATION; METABOLIC REGULATION; MITOCHONDRIAL RESPIRATION; MOUSE; MUTAGENESIS; NONHUMAN; PROTEIN ACETYLATION; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; ACETYLATION; ANIMAL; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; MITOCHONDRION; SIZE EXCLUSION CHROMATOGRAPHY; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ACETYLATION; ANIMALS; CHAPERONIN 10; CHROMATOGRAPHY, GEL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FASTING; FATTY ACIDS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MOLECULAR CHAPERONES; MUTAGENESIS; OXYGEN; PROTEIN FOLDING; REACTIVE OXYGEN SPECIES; SIRTUIN 3;

EID: 84922031813     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.606228     Document Type: Article

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