GDF15 derived from both tumor-associated macrophages and esophageal squamous cell carcinomas contributes to tumor progression via Akt and Erk pathways

Laboratory Investigation

Volumn 95, Issue 5, 2015, Pages 491-503

  Urakawa, Naoki ^a   Utsunomiya, Soken ^a   Nishio, Mari ^a   Shigeoka, Manabu ^a,b   Takase, Nobuhisa ^a   Arai, Noriaki ^a   Kakeji, Yoshihiro ^a   Koma, Yu Ichiro ^a   Yokozaki, Hiroshi ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KOBE UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CXCL1 CHEMOKINE; CXCL13 CHEMOKINE; FIBROBLAST GROWTH FACTOR 5; GELATINASE A; GELATINASE B; GROWTH DIFFERENTIATION FACTOR 15; INTERLEUKIN 10; INTERLEUKIN 12P35; INTERLEUKIN 6; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOGENIC PROTEIN 1; PROTEIN KINASE B; SECONDARY LYMPHOID TISSUE CHEMOKINE; VASCULOTROPIN A; CULTURE MEDIUM; CYTOKINE;

ADULT; AGED; ARTICLE; CANCER GROWTH; CANCER PROGNOSIS; CANCER SURVIVAL; CELL INVASION; CELL PROLIFERATION; CLINICAL ARTICLE; DISEASE FREE SURVIVAL; DNA MICROARRAY; ESOPHAGEAL CANCER CELL LINE; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MALE; MULTICENTER STUDY (TOPIC); NUCLEOTIDE SEQUENCE; OVERALL SURVIVAL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR ASSOCIATED LEUKOCYTE; TUMOR INVASION; TUMOR MICROENVIRONMENT; UPREGULATION; CHEMISTRY; CULTURE MEDIUM; DRUG EFFECTS; ESOPHAGUS TUMOR; GENETICS; MACROPHAGE; METABOLISM; MONONUCLEAR CELL; PHARMACOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE;

CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; CULTURE MEDIA, CONDITIONED; CYTOKINES; ESOPHAGEAL NEOPLASMS; GROWTH DIFFERENTIATION FACTOR 15; HUMANS; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; TUMOR MICROENVIRONMENT;

EID: 84929078173     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2015.36     Document Type: Article

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