Growth differentiation factor 15 stimulates rapamycin-sensitive ovarian cancer cell growth and invasion

Biochemical Pharmacology

Volumn 85, Issue 1, 2013, Pages 46-58

  Griner, Samantha E ^a,b   Joshi, Jayashree P ^a,b   Nahta, Rita ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

GDF15; Invasion; mTOR; Ovarian cancer; PI3K; Rapamycin

Indexed keywords

ANTINEOPLASTIC AGENT; GELATINASE B; GROWTH DIFFERENTIATION FACTOR 15; MATRIX METALLOPROTEINASE; PROTEIN KINASE B; RAPAMYCIN; RECOMBINANT GROWTH DIFFERENTIATION FACTOR 15; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER GROWTH; CANCER INVASION; CELL GROWTH; CELL INVASION; CELL PROLIFERATION; FEMALE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOHISTOCHEMISTRY; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TUMOR; CELL PROLIFERATION; DIPEPTIDES; FEMALE; GENE KNOCKDOWN TECHNIQUES; GROWTH DIFFERENTIATION FACTOR 15; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM INVASIVENESS; OVARIAN NEOPLASMS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES;

EID: 84871711834     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.10.007     Document Type: Article

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