'N-of-1-pathways' unveils personal deregulated mechanisms from a single pair of RNA-seq samples: Towards precision medicine

Journal of the American Medical Informatics Association

Volumn 21, Issue 6, 2014, Pages 1015-1025

  Gardeux, Vincent ^a,b,c   Achour, Ikbel ^a,b   Li, Jianrong ^a,b   Maienschein Cline, Mark ^b   Li, Haiquan ^a,b   Pesce, Lorenzo ^d   Parinandi, Gurunadh ^b   Bahroos, Neil ^b   Winn, Robert ^b   Foster, Ian ^d,e,f   Garcia, Joe G N ^a   Lussier, Yves A ^a,b,d,g,h  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c UNIVERSITÉ DE CERGY PONTOISE   (France)

^d UNIVERSITY OF CHICAGO   (United States)

^e THE UNIVERSITY OF CHICAGO   (United States)

^f ARGONNE NATIONAL LABORATORY   (United States)

^g University of Illinois at Chicago   (United States)

^h UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RNA; TRANSCRIPTOME; GENETIC MARKER; TUMOR MARKER;

ARTICLE; CANCER MORTALITY; CANCER SURVIVAL; CLINICAL TRIAL (TOPIC); CONCEPTUAL FRAMEWORK; DEREGULATION; DISEASE FREE SURVIVAL; DNA REPAIR; DNA SEQUENCE; EARLY CANCER; GENE EXPRESSION; GENE ONTOLOGY; GENETIC ANALYSIS; GOLD STANDARD; HUMAN; LUNG ADENOCARCINOMA; LUNG PARENCHYMA; PATIENT CARE; PHENOTYPE; PRINCIPAL COMPONENT ANALYSIS; REGULATORY MECHANISM; RNA SEQUENCE; SIGNAL TRANSDUCTION; SOMATIC MUTATION; TUMOR GROWTH; TUMOR RECURRENCE; UPREGULATION; VALIDATION STUDY; ADENOCARCINOMA; ADULT; AGED; BIOLOGY; DNA MICROARRAY; FEMALE; GENE EXPRESSION PROFILING; GENETIC MARKER; GENETICS; LUNG TUMOR; MALE; MIDDLE AGED; MUTATION; SEQUENCE ANALYSIS; VERY ELDERLY;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; COMPUTATIONAL BIOLOGY; DISEASE-FREE SURVIVAL; FEMALE; GENE EXPRESSION PROFILING; GENETIC MARKERS; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PATIENT-CENTERED CARE; RNA; RNA, NEOPLASM; SEQUENCE ANALYSIS, RNA; TRANSCRIPTOME; TUMOR MARKERS, BIOLOGICAL;

EID: 84929047446     PISSN: 10675027     EISSN: 1527974X     Source Type: Journal    
DOI: 10.1136/amiajnl-2013-002519     Document Type: Article

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