Network modeling identifies molecular functions targeted by miR-204 to suppress head and neck tumor metastasis

PLoS Computational Biology

Volumn 6, Issue 4, 2010, Pages

  Lee, Younghee ^a   Yang, Xinan ^a   Huang, Yong ^a   Fan, Hanli ^b   Zhang, Qingbei ^b   Wu, Youngfei ^b   Li, Jianrong ^a   Hasina, Rifat ^b   Cheng, Chao ^c   Lingen, Mark W ^b,d   Gerstein, Mark B ^c   Weichselbaum, Ralph R ^d   Xing, H Rosie ^b,d   Lussier, Yves A ^a,d,e  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CHICAGO   (United States)

^e UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; DISEASES; NETWORK TOPOLOGY; PATHOLOGY; RISK ASSESSMENT; RNA; TUMORS;

BIOLOGICAL PROCESS; GENOMIC REGIONS; HEAD-AND-NECK TUMOR; MOLECULAR FUNCTION; NETWORK MODELS; NETWORK TOPOLOGY; RISK FACTORS; SEQUENCE ALIGNMENTS; TUMOR METASTASIS; TUMOUR SUPPRESSOR GENES;

GENE EXPRESSION;

EPIDERMAL GROWTH FACTOR RECEPTOR; MICRORNA; MICRORNA 204; UNCLASSIFIED DRUG; EGFR PROTEIN, HUMAN; MIRN204 MICRORNA, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER RELAPSE; CANCER SUSCEPTIBILITY; CELL ADHESION; CELL INVASION; CELL MIGRATION; CHROMOSOME 9Q; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE EXPRESSION PROFILING; GENE LOCUS; GENETIC PREDISPOSITION; GENETIC RISK; HEAD AND NECK TUMOR; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; LUNG METASTASIS; MALIGNANT TRANSFORMATION; METASTASIS INHIBITION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PREDICTION; PROTEIN PROTEIN INTERACTION; SQUAMOUS CELL CARCINOMA; TUMOR GROWTH; TUMOR SUPPRESSOR GENE; BIOLOGY; CELL MOTION; CHROMOSOME 9; GENE EXPRESSION REGULATION; GENETICS; HUMAN GENOME; METABOLISM; METASTASIS; METHODOLOGY; PATHOLOGY; PROTEIN ANALYSIS; TUMOR CELL LINE;

CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CHROMOSOMES, HUMAN, PAIR 9; COMPUTATIONAL BIOLOGY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; HEAD AND NECK NEOPLASMS; HUMANS; LOSS OF HETEROZYGOSITY; MICRORNAS; NEOPLASM METASTASIS; PROTEIN INTERACTION MAPPING; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 77952742610     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000730     Document Type: Article

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