Genetic deficiency of Mtdh gene in mice causes male infertility via impaired spermatogenesis and alterations in the expression of small non-coding RNAs

Journal of Biological Chemistry

Volumn 290, Issue 19, 2015, Pages 11853-11864

  Meng, Xiangbing ^a,b   Yang, Shujie ^a,b   Zhang, Yuping ^a   Wang, Xinjun ^a   Goodfellow, Renee X ^a   Jia, Yichen ^a   Thiel, Kristina W ^a   Reyes, Henry D ^a   Yang, Baoli ^a   Leslie, Kimberly K ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DRUG THERAPY; GENE EXPRESSION; NUCLEIC ACIDS; PROTEINS; RNA; TRANSCRIPTION;

DNA REPAIR PROTEINS; DRUG RESISTANCE; GENETIC DEFICIENCIES; MALE FERTILITY; MALE INFERTILITY; NON-CODING RNAS; POST-TRANSCRIPTIONAL; SEMINIFEROUS TUBULES;

MAMMALS;

HISTONE H2AX; MICRORNA; MICRORNA 16; MICRORNA 19B; PIWI INTERACTING RNA; RAD18 PROTEIN; SMALL UNTRANSLATED RNA; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; MIRN16 MICRORNA, MOUSE; MIRN19 MICRORNA, MOUSE; MTDH PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL VACUOLE; CONTROLLED STUDY; DNA STRAND BREAKAGE; EMBRYO; EXON; GENE DELETION; GENE DISRUPTION; GENE TARGETING; GENETIC DISORDER; HOMOZYGOSITY; MALE; MALE INFERTILITY; MARKER GENE; MEIOSIS; METADHERIN GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA SEQUENCE; SEMINIFEROUS TUBULE; SPERMATOCYTE; SPERMATOGENESIS; TESTICULAR DEGENERATION; TESTIS DISEASE; ANIMAL; DNA DAMAGE; DNA REPAIR; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION REGULATION; GENETICS; GENOTYPE; HOMOZYGOTE; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; SPERMATOZOON; TESTIS;

MUS;

ANIMALS; DNA DAMAGE; DNA REPAIR; EXONS; GENE DELETION; GENE EXPRESSION REGULATION; GENOTYPE; HOMOZYGOTE; IN SITU HYBRIDIZATION, FLUORESCENCE; INFERTILITY, MALE; MALE; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MICRORNAS; RNA, SMALL UNTRANSLATED; SPERMATOCYTES; SPERMATOGENESIS; SPERMATOZOA; TESTIS;

EID: 84929008722     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.627653     Document Type: Article

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