MTDH-SND1 Interaction Is Crucial for Expansion and Activity of Tumor-Initiating Cells in Diverse Oncogene- and Carcinogen-Induced Mammary Tumors

Cancer Cell

Volumn 26, Issue 1, 2014, Pages 92-105

  Wan, Liling ^a   Lu, Xin ^a   Yuan, Salina ^a   Wei, Yong ^a   Guo, Feng ^b   Shen, Minhong ^a   Yuan, Min ^a   Chakrabarti, Rumela ^a   Hua, Yuling ^a   Smith, HeathA ^a   Blanco, MarioAndres ^a   Chekmareva, Marina ^c   Wu, Hao ^d   Bronson, RoderickT ^e   Haffty, BruceG ^d   Xing, Yongna ^b   Kang, Yibin ^a,d,e,f  

^a PRINCETON UNIVERSITY   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^d RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CARCINOGEN; STAPHYLOCOCCAL NUCLEASE DOMAIN CONTAINING 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST TUMOR; CELL ACTIVITY; CELL EXPANSION; CONTROLLED STUDY; GENE SILENCING; HUMAN; HUMAN CELL; IN VIVO STUDY; METADHERIN GENE; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; BREAST NEOPLASMS; CELL ADHESION MOLECULES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CELL TRANSFORMATION, VIRAL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; HEK293 CELLS; HUMANS; MAMMARY GLANDS, ANIMAL; MAMMARY TUMOR VIRUS, MOUSE; MEDROXYPROGESTERONE ACETATE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; NEOPLASM INVASIVENESS; NEOPLASTIC STEM CELLS; NUCLEAR PROTEINS; PHENOTYPE; PROTEIN BINDING; RNA INTERFERENCE; TIME FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 84904319393     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccr.2014.04.027     Document Type: Article

References (31)

1. Asselin-Labat M.L., Sutherland K.D., Barker H., Thomas R., Shackleton M., Forrest N.C., Hartley L., Robb L., Grosveld F.G., van der Wees J., et al. Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation. Nat. Cell Biol. 2007, 9:201-209.
2. Bernards R., Weinberg R.A. A progression puzzle. Nature 2002, 418:823.
3. Blanco M.A., Alečković M., Hua Y., Li T., Wei Y., Xu Z., Cristea I.M., Kang Y. Identification of staphylococcal nuclease domain-containing 1 (SND1) as a Metadherin-interacting protein with metastasis-promoting functions. J.Biol. Chem. 2011, 286:19982-19992.
4. Brown D.M., Ruoslahti E. Metadherin, a cell surface protein in breast tumors that mediates lung metastasis. Cancer Cell 2004, 5:365-374.
5. Buchwalter G., Hickey M.M., Cromer A., Selfors L.M., Gunawardane R.N., Frishman J., Jeselsohn R., Lim E., Chi D., Fu X., et al. PDEF promotes luminal differentiation and acts as a survival factor for ER-positive breast cancer cells. Cancer Cell 2013, 23:753-767.
6. DeRose Y.S., Wang G., Lin Y.C., Bernard P.S., Buys S.S., Ebbert M.T., Factor R., Matsen C., Milash B.A., Nelson E., et al. Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes. Nat. Med. 2011, 17:1514-1520.
7. Emdad L., Das S.K., Dasgupta S., Hu B., Sarkar D., Fisher P.B. AEG-1/MTDH/LYRIC: signaling pathways, downstream genes, interacting proteins, and regulation of tumor angiogenesis. Adv. Cancer Res. 2013, 120:75-111.
8. Gao X., Ge L., Shao J., Su C., Zhao H., Saarikettu J., Yao X., Yao Z., Silvennoinen O., Yang J. Tudor-SN interacts with and co-localizes with G3BP in stress granules under stress conditions. FEBS Lett. 2010, 584:3525-3532.
9. Ginestier C., Hur M.H., Charafe-Jauffret E., Monville F., Dutcher J., Brown M., Jacquemier J., Viens P., Kleer C.G., Liu S., et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 2007, 1:555-567.
10. Guo W., Keckesova Z., Donaher J.L., Shibue T., Tischler V., Reinhardt F., Itzkovitz S., Noske A., Zürrer-Härdi U., Bell G., et al. Slug and Sox9 cooperatively determine the mammary stem cell state. Cell 2012, 148:1015-1028.
11. Halazonetis T.D., Gorgoulis V.G., Bartek J. An oncogene-induced DNA damage model for cancer development. Science 2008, 319:1352-1355.
12. Herschkowitz J.I., Simin K., Weigman V.J., Mikaelian I., Usary J., Hu Z., Rasmussen K.E., Jones L.P., Assefnia S., Chandrasekharan S., et al. Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol. 2007, 8:R76.
13. Hu G., Chong R.A., Yang Q., Wei Y., Blanco M.A., Li F., Reiss M., Au J.L., Haffty B.G., Kang Y. MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer. Cancer Cell 2009, 15:9-20.
14. Kouros-Mehr H., Bechis S.K., Slorach E.M., Littlepage L.E., Egeblad M., Ewald A.J., Pai S.Y., Ho I.C., Werb Z. GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model. Cancer Cell 2008, 13:141-152.
15. Lento W., Congdon K., Voermans C., Kritzik M., Reya T. Wnt signaling in normal and malignant hematopoiesis. Cold Spring Harb. Perspect. Biol. 2013, 5:5.
16. Li Y., Welm B., Podsypanina K., Huang S., Chamorro M., Zhang X., Rowlands T., Egeblad M., Cowin P., Werb Z., et al. Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells. Proc. Natl. Acad. Sci. USA 2003, 100:15853-15858.
17. Mani S.A., Guo W., Liao M.J., Eaton E.N., Ayyanan A., Zhou A.Y., Brooks M., Reinhard F., Zhang C.C., Shipitsin M., et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008, 133:704-715.
18. Meng X., Zhu D., Yang S., Wang X., Xiong Z., Zhang Y., Brachova P., Leslie K.K. Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein. J.Biol. Chem. 2012, 287:4485-4491.
19. Perou C.M., Sørlie T., Eisen M.B., van de Rijn M., Jeffrey S.S., Rees C.A., Pollack J.R., Ross D.T., Johnsen H., Akslen L.A., et al. Molecular portraits of human breast tumours. Nature 2000, 406:747-752.
20. Shackleton M., Vaillant F., Simpson K.J., Stingl J., Smyth G.K., Asselin-Labat M.L., Wu L., Lindeman G.J., Visvader J.E. Generation of a functional mammary gland from a single stem cell. Nature 2006, 439:84-88.
21. Sundström J.F., Vaculova A., Smertenko A.P., Savenkov E.I., Golovko A., Minina E., Tiwari B.S., Rodriguez-Nieto S., Zamyatnin A.A., Välineva T., et al. Tudor staphylococcal nuclease is an evolutionarily conserved component of the programmed cell death degradome. Nat. Cell Biol. 2009, 11:1347-1354.
22. Vaillant F., Asselin-Labat M.L., Shackleton M., Forrest N.C., Lindeman G.J., Visvader J.E. The mammary progenitor marker CD61/beta3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis. Cancer Res. 2008, 68:7711-7717.
23. van de Vijver M.J., He Y.D., van't Veer L.J., Dai H., Hart A.A., Voskuil D.W., Schreiber G.J., Peterse J.L., Roberts C., Marton M.J., et al. A gene-expression signature as a predictor of survival in breast cancer. N.Engl. J. Med. 2002, 347:1999-2009.
24. Vanharanta S., Massagué J. Origins of metastatic traits. Cancer Cell 2013, 24:410-421.
25. Wan L., Kang Y. Pleiotropic roles of AEG-1/MTDH/LYRIC in breast cancer. Adv. Cancer Res. 2013, 120:113-134.
26. Wan L., Pantel K., Kang Y. Tumor metastasis: moving new biological insights into the clinic. Nat. Med. 2013, 19:1450-1464.
27. Weissbach R., Scadden A.D. Tudor-SN and ADAR1 are components of cytoplasmic stress granules. RNA 2012, 18:462-471.
28. Yin Y., Bai R., Russell R.G., Beildeck M.E., Xie Z., Kopelovich L., Glazer R.I. Characterization of medroxyprogesterone and DMBA-induced multilineage mammary tumors by gene expression profiling. Mol. Carcinog. 2005, 44:42-50.
29. Yoo B.K., Santhekadur P.K., Gredler R., Chen D., Emdad L., Bhutia S., Pannell L., Fisher P.B., Sarkar D. Increased RNA-induced silencing complex (RISC) activity contributes to hepatocellular carcinoma. Hepatology 2011, 53:1538-1548.
30. Zhang W., Tan W., Wu X., Poustovoitov M., Strasner A., Li W., Borcherding N., Ghassemian M., Karin M. A NIK-IKKα module expands ErbB2-induced tumor-initiating cells by stimulating nuclear export of p27/Kip1. Cancer Cell 2013, 23:647-659.
31. Zhang X., Claerhout S., Prat A., Dobrolecki L.E., Petrovic I., Lai Q., Landis M.D., Wiechmann L., Schiff R., Giuliano M., et al. A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models. Cancer Res. 2013, 73:4885-4897.