-
2
-
-
84879197444
-
Metabolic derangements in the gastrocnemius and the effect of CompoundAtherapy in a murine model of cancer cachexia
-
Der-Torossian H, Wysong A, Shadfar S, Willis MS, McDunn J, Couch ME. Metabolic derangements in the gastrocnemius and the effect of CompoundAtherapy in a murine model of cancer cachexia. J Cachexia Sarcopenia Muscle. 2013;4:145-155.
-
(2013)
J Cachexia Sarcopenia Muscle.
, vol.4
, pp. 145-155
-
-
Der-Torossian, H.1
Wysong, A.2
Shadfar, S.3
Willis, M.S.4
McDunn, J.5
Couch, M.E.6
-
3
-
-
84893442805
-
Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging
-
Gomes AP, Price NL, Ling AJ, et al. Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Cell. 2013;155:1624-1638.
-
(2013)
Cell.
, vol.155
, pp. 1624-1638
-
-
Gomes, A.P.1
Price, N.L.2
Ling, A.J.3
-
4
-
-
0026554586
-
Contribution of skeletal muscle atrophy to exercise intolerance and altered muscle metabolism in heart failure
-
Mancini DM, Walter G, Reichek N, et al. Contribution of skeletal muscle atrophy to exercise intolerance and altered muscle metabolism in heart failure. Circulation. 1992;85:1364-1373.
-
(1992)
Circulation.
, vol.85
, pp. 1364-1373
-
-
Mancini, D.M.1
Walter, G.2
Reichek, N.3
-
5
-
-
0029161457
-
Exercise intolerance in patients with chronic heart failure
-
Sullivan MJ, Hawthorne MH. Exercise intolerance in patients with chronic heart failure. Prog Cardiovasc Dis. 1995;38:1-22.
-
(1995)
Prog Cardiovasc Dis.
, vol.38
, pp. 1-22
-
-
Sullivan, M.J.1
Hawthorne, M.H.2
-
6
-
-
79251603865
-
Development of disability in chronic obstructive pulmonary disease: Beyond lung function
-
Eisner MD, Iribarren C, Blanc PD, et al. Development of disability in chronic obstructive pulmonary disease: beyond lung function. Thorax. 2011;66:108-114.
-
(2011)
Thorax.
, vol.66
, pp. 108-114
-
-
Eisner, M.D.1
Iribarren, C.2
Blanc, P.D.3
-
7
-
-
33748286777
-
Decreased muscle strength and quality in older adults with type 2 diabetes: The health, aging, and body composition study
-
Park SW, Goodpaster BH, Strotmeyer ES, et al. Decreased muscle strength and quality in older adults with type 2 diabetes: the health, aging, and body composition study. Diabetes. 2006;55:1813-1818.
-
(2006)
Diabetes.
, vol.55
, pp. 1813-1818
-
-
Park, S.W.1
Goodpaster, B.H.2
Strotmeyer, E.S.3
-
9
-
-
42949110715
-
Peroxisome proliferator-activated receptors: A therapeutic target in COPD?
-
Remels AH, Gosker HR, Schrauwen P, Langen RC, Schols AM. Peroxisome proliferator-activated receptors: a therapeutic target in COPD? Eur Respir J. 2008;31:502-508.
-
(2008)
Eur Respir J.
, vol.31
, pp. 502-508
-
-
Remels, A.H.1
Gosker, H.R.2
Schrauwen, P.3
Langen, R.C.4
Schols, A.M.5
-
10
-
-
34447547592
-
Reduced mitochondrial density in the vastus lateralis muscle of patients with COPD
-
Gosker HR, Hesselink MK, Duimel H, Ward KA, Schols AM. Reduced mitochondrial density in the vastus lateralis muscle of patients with COPD. Eur Respir J. 2007;30:73-79.
-
(2007)
Eur Respir J.
, vol.30
, pp. 73-79
-
-
Gosker, H.R.1
Hesselink, M.K.2
Duimel, H.3
Ward, K.A.4
Schols, A.M.5
-
11
-
-
0036205728
-
Skeletal muscle fibre-type shifting and metabolic profile in patients with chronic obstructive pulmonary disease
-
Gosker HR, van Mameren H, van Dijk PJ, et al. Skeletal muscle fibre-type shifting and metabolic profile in patients with chronic obstructive pulmonary disease. Eur Respir J. 2002;19:617-625.
-
(2002)
Eur Respir J.
, vol.19
, pp. 617-625
-
-
Gosker, H.R.1
Van Mameren, H.2
Van Dijk, P.J.3
-
12
-
-
34147131849
-
Mitochondrial dysfunction in COPD patients with low body mass index
-
Rabinovich RA, Bastos R, Ardite E, et al. Mitochondrial dysfunction in COPD patients with low body mass index. Eur Respir J. 2007;29:643-650.
-
(2007)
Eur Respir J.
, vol.29
, pp. 643-650
-
-
Rabinovich, R.A.1
Bastos, R.2
Ardite, E.3
-
13
-
-
79251508705
-
Quadriceps metabolism during constant work rate cycling exercise in chronic obstructive pulmonary disease
-
Saey D, Lemire BB, Gagnon P, et al. Quadriceps metabolism during constant work rate cycling exercise in chronic obstructive pulmonary disease. J Appl Physiol. 2011;110:116-124.
-
(2011)
J Appl Physiol.
, vol.110
, pp. 116-124
-
-
Saey, D.1
Lemire, B.B.2
Gagnon, P.3
-
14
-
-
79959334213
-
Increased postabsorptive and exercise-induced whole-body glucose production in patients with chronic obstructive pulmonary disease
-
Franssen FM, Sauerwein HP, Ackermans MT, Rutten EP, Wouters EF, Schols AM. Increased postabsorptive and exercise-induced whole-body glucose production in patients with chronic obstructive pulmonary disease. Metabolism. 2011;60:957-964.
-
(2011)
Metabolism.
, vol.60
, pp. 957-964
-
-
Franssen, F.M.1
Sauerwein, H.P.2
Ackermans, M.T.3
Rutten, E.P.4
Wouters, E.F.5
Schols, A.M.6
-
15
-
-
54049136846
-
Organization of metabolic pathways in vastus lateralis of patients with chronic obstructive pulmonary disease
-
Green HJ, Bombardier E, Burnett M, et al. Organization of metabolic pathways in vastus lateralis of patients with chronic obstructive pulmonary disease. Am J Physiol Regul Integr Comp Physiol. 2008;295:R935-R941.
-
(2008)
Am J Physiol Regul Integr Comp Physiol.
, vol.295
, pp. R935-R941
-
-
Green, H.J.1
Bombardier, E.2
Burnett, M.3
-
16
-
-
53049083078
-
Altered metabolic and transporter characteristics of vastus lateralis in chronic obstructive pulmonary disease
-
Green HJ, Burnett ME, D'Arsigny CL, O'Donnell DE, Ouyang J, Webb KA. Altered metabolic and transporter characteristics of vastus lateralis in chronic obstructive pulmonary disease. J Appl Physiol. 2008;105:879-886.
-
(2008)
J Appl Physiol.
, vol.105
, pp. 879-886
-
-
Green, H.J.1
Burnett, M.E.2
D'Arsigny, C.L.3
O'Donnell, D.E.4
Ouyang, J.5
Webb, K.A.6
-
17
-
-
0028878473
-
Metabolic enzyme activity in the quadriceps femoris muscle in patients with severe chronic obstructive pulmonary disease
-
Jakobsson P, Jorfeldt L, Henriksson J. Metabolic enzyme activity in the quadriceps femoris muscle in patients with severe chronic obstructive pulmonary disease.AmJ Respir Crit Care Med. 1995;151: 374-377.
-
(1995)
AmJ Respir Crit Care Med.
, vol.151
, pp. 374-377
-
-
Jakobsson, P.1
Jorfeldt, L.2
Henriksson, J.3
-
18
-
-
60249098269
-
Skeletal muscle dysfunction in patients with chronic obstructive pulmonary disease
-
Kim HC, Mofarrahi M, Hussain SN. Skeletal muscle dysfunction in patients with chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2008;3:637-658.
-
(2008)
Int J Chron Obstruct Pulmon Dis.
, vol.3
, pp. 637-658
-
-
Kim, H.C.1
Mofarrahi, M.2
Hussain, S.N.3
-
19
-
-
78649743322
-
TNF-α impairs regulation of muscle oxidative phenotype: Implications for cachexia?
-
Remels AH, Gosker HR, Schrauwen P, et al. TNF-α impairs regulation of muscle oxidative phenotype: implications for cachexia? FASEB J. 2010;24:5052-5062.
-
(2010)
FASEB J.
, vol.24
, pp. 5052-5062
-
-
Remels, A.H.1
Gosker, H.R.2
Schrauwen, P.3
-
20
-
-
0027765624
-
Cachectin/TNF-mediated lactate production in cultured myocytes is linked to activation of a futile substrate cycle
-
Zentella A, Manogue K, Cerami A. Cachectin/TNF-mediated lactate production in cultured myocytes is linked to activation of a futile substrate cycle. Cytokine. 1993;5:436-447.
-
(1993)
Cytokine.
, vol.5
, pp. 436-447
-
-
Zentella, A.1
Manogue, K.2
Cerami, A.3
-
21
-
-
0034017489
-
Development of a hypoxia-responsive vector for tumor-specific gene therapy
-
Shibata T, Giaccia AJ, Brown JM. Development of a hypoxia-responsive vector for tumor-specific gene therapy. Gene Ther. 2000; 7:493-498.
-
(2000)
Gene Ther.
, vol.7
, pp. 493-498
-
-
Shibata, T.1
Giaccia, A.J.2
Brown, J.M.3
-
22
-
-
84878602063
-
Loss of quadriceps muscle oxidative phenotype and decreased endurance in patients with mild-to-moderate COPD
-
van den Borst B, Slot IG, Hellwig VA, et al. Loss of quadriceps muscle oxidative phenotype and decreased endurance in patients with mild-to-moderate COPD. J Appl Physiol. 2012;9:1319-1328.
-
(2012)
J Appl Physiol.
, vol.9
, pp. 1319-1328
-
-
Van Den Borst, B.1
Slot, I.G.2
Hellwig, V.A.3
-
23
-
-
84928993459
-
Regulation of skeletal muscle oxidative phenotype by classical NF-κB signalling
-
Remels AH, Gosker HR, Bakker J, Guttridge DC, Schols AM, Langen RC. Regulation of skeletal muscle oxidative phenotype by classical NF-κB signalling. Biochim Biophys Acta. 2013;81:313-325.
-
(2013)
Biochim Biophys Acta.
, vol.81
, pp. 313-325
-
-
Remels, A.H.1
Gosker, H.R.2
Bakker, J.3
Guttridge, D.C.4
Schols, A.M.5
Langen, R.C.6
-
24
-
-
0242710750
-
Hypoxic regulation of the 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase gene family (PFKFB-1-4) expression in vivo
-
Minchenko O, Opentanova I, Caro J. Hypoxic regulation of the 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase gene family (PFKFB-1-4) expression in vivo. FEBS Lett. 2003;554:264-270.
-
(2003)
FEBS Lett.
, vol.554
, pp. 264-270
-
-
Minchenko, O.1
Opentanova, I.2
Caro, J.3
-
25
-
-
84884640761
-
Regulation of the expression and activity of glucose and lactic acid metabolism-related genes by protein kinase C in skeletal muscle cells
-
Otake S, Kobayashi M, Narumi K, et al. Regulation of the expression and activity of glucose and lactic acid metabolism-related genes by protein kinase C in skeletal muscle cells. Biol Pharm Bull. 2013; 36:1435-1439.
-
(2013)
Biol Pharm Bull.
, vol.36
, pp. 1435-1439
-
-
Otake, S.1
Kobayashi, M.2
Narumi, K.3
-
26
-
-
70449407298
-
The response of human skeletal muscle tissue to hypoxia
-
Lundby C, Calbet JA, Robach P. The response of human skeletal muscle tissue to hypoxia. Cell Mol Life Sci. 2009;66:3615-3623.
-
(2009)
Cell Mol Life Sci.
, vol.66
, pp. 3615-3623
-
-
Lundby, C.1
Calbet, J.A.2
Robach, P.3
-
27
-
-
33749442351
-
TNF-α downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents
-
Valerio A, Cardile A, Cozzi V, et al. TNF-α downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents. J Clin Invest. 2006;116:2791-2798.
-
(2006)
J Clin Invest.
, vol.116
, pp. 2791-2798
-
-
Valerio, A.1
Cardile, A.2
Cozzi, V.3
-
28
-
-
77956342883
-
TNF-α induces mitochondrial dysfunction in 3T3-L1 adipocytes
-
Chen XH, Zhao YP, Xue M, et al. TNF-α induces mitochondrial dysfunction in 3T3-L1 adipocytes. Mol Cell Endocrinol. 2010;328: 63-69.
-
(2010)
Mol Cell Endocrinol.
, vol.328
, pp. 63-69
-
-
Chen, X.H.1
Zhao, Y.P.2
Xue, M.3
-
29
-
-
61449199440
-
Proteomic analysis of mitochondrial proteins of basal and lipolytically (isoproterenol and TNF-α)-stimulated adipocytes
-
Cho SY, Park PJ, Shin ES, Lee JH, Chang HK, Lee TR. Proteomic analysis of mitochondrial proteins of basal and lipolytically (isoproterenol and TNF-α)-stimulated adipocytes. J Cell Biochem. 2009;106:257-266.
-
(2009)
J Cell Biochem.
, vol.106
, pp. 257-266
-
-
Cho, S.Y.1
Park, P.J.2
Shin, E.S.3
Lee, J.H.4
Chang, H.K.5
Lee, T.R.6
-
30
-
-
0037453028
-
Oxidative stress mediates tumor necrosis factor-α-induced mitochondrial DNA damage and dysfunction in cardiac myocytes
-
Suematsu N, Tsutsui H, Wen J, et al. Oxidative stress mediates tumor necrosis factor-α-induced mitochondrial DNA damage and dysfunction in cardiac myocytes. Circulation. 2003;107:1418-1423.
-
(2003)
Circulation.
, vol.107
, pp. 1418-1423
-
-
Suematsu, N.1
Tsutsui, H.2
Wen, J.3
-
32
-
-
0033677088
-
The proinflammatory mediator macrophage migration inhibitory factor induces glucose catabolism in muscle
-
Benigni F, Atsumi T, Calandra T, et al. The proinflammatory mediator macrophage migration inhibitory factor induces glucose catabolism in muscle. J Clin Invest. 2000;106:1291-1300.
-
(2000)
J Clin Invest.
, vol.106
, pp. 1291-1300
-
-
Benigni, F.1
Atsumi, T.2
Calandra, T.3
-
33
-
-
84906055605
-
Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes
-
Esser N, Legrand-Poels S, Piette J, Scheen AJ, Paquot N. Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes. Diabetes Res Clin Pract. 2014;14:187-189.
-
(2014)
Diabetes Res Clin Pract.
, vol.14
, pp. 187-189
-
-
Esser, N.1
Legrand-Poels, S.2
Piette, J.3
Scheen, A.J.4
Paquot, N.5
-
34
-
-
81155125114
-
Alterations of the hypothalamic- pituitary-adrenal axis in systemic immune diseases-A role for misguided energy regulation
-
Straub RH, Buttgereit F, Cutolo M. Alterations of the hypothalamic- pituitary-adrenal axis in systemic immune diseases-a role for misguided energy regulation. Clin Exp Rheumatol. 2011;29:S23-S31.
-
(2011)
Clin Exp Rheumatol.
, vol.29
, pp. S23-S31
-
-
Straub, R.H.1
Buttgereit, F.2
Cutolo, M.3
-
35
-
-
77951935429
-
Energy regulation and neuroendocrine-immune control in chronic inflammatory diseases
-
Straub RH, Cutolo M, Buttgereit F, Pongratz G. Energy regulation and neuroendocrine-immune control in chronic inflammatory diseases. J Intern Med. 2010;267:543-560.
-
(2010)
J Intern Med.
, vol.267
, pp. 543-560
-
-
Straub, R.H.1
Cutolo, M.2
Buttgereit, F.3
Pongratz, G.4
-
36
-
-
43049139541
-
P53 regulates glucose metabolism through an IKK-NF-κB pathway and inhibits cell transformation
-
Kawauchi K, Araki K, Tobiume K, Tanaka N. p53 regulates glucose metabolism through an IKK-NF-κB pathway and inhibits cell transformation. Nat Cell Biol. 2008;10:611-618.
-
(2008)
Nat Cell Biol.
, vol.10
, pp. 611-618
-
-
Kawauchi, K.1
Araki, K.2
Tobiume, K.3
Tanaka, N.4
-
37
-
-
84867375467
-
Role of PGC-1α signaling in skeletal muscle health and disease
-
Kang C, Li Ji L. Role of PGC-1α signaling in skeletal muscle health and disease. Ann NY Acad Sci. 2012;1271:110-117.
-
(2012)
Ann NY Acad Sci.
, vol.1271
, pp. 110-117
-
-
Kang, C.1
Li Ji, L.2
-
38
-
-
84862854714
-
Hypoxia-inducible factors and their roles in energy metabolism
-
Goda N, Kanai M. Hypoxia-inducible factors and their roles in energy metabolism. Int J Hematol. 2012;95:457-463.
-
(2012)
Int J Hematol.
, vol.95
, pp. 457-463
-
-
Goda, N.1
Kanai, M.2
-
39
-
-
0037372369
-
Cytokines induce HIF-1 DNA binding and the expression of HIF-1-dependent genes in cultured rat enterocytes
-
Scharte M, Han X, Bertges DJ, Fink MP, Delude RL. Cytokines induce HIF-1 DNA binding and the expression of HIF-1-dependent genes in cultured rat enterocytes. Am J Physiol Gastrointest Liver Physiol. 2003;284:G373-G384.
-
(2003)
Am J Physiol Gastrointest Liver Physiol.
, vol.284
, pp. G373-G384
-
-
Scharte, M.1
Han, X.2
Bertges, D.J.3
Fink, M.P.4
Delude, R.L.5
-
40
-
-
33748772543
-
LPS increases hepatic HIF-1α protein and expression of the HIF-1-dependent gene aldolaseAin rats
-
Scharte M, Han X, Uchiyama T, Tawadrous Z, Delude RL, Fink MP. LPS increases hepatic HIF-1α protein and expression of the HIF-1-dependent gene aldolaseAin rats. J Surg Res. 2006;135:262-267.
-
(2006)
J Surg Res.
, vol.135
, pp. 262-267
-
-
Scharte, M.1
Han, X.2
Uchiyama, T.3
Tawadrous, Z.4
Delude, R.L.5
Fink, M.P.6
-
41
-
-
51749089798
-
Interdependent roles for hypoxia inducible factor and nuclear factor-κB in hypoxic inflammation
-
Taylor CT. Interdependent roles for hypoxia inducible factor and nuclear factor-κB in hypoxic inflammation. J Physiol. 2008;586: 4055-4059.
-
(2008)
J Physiol.
, vol.586
, pp. 4055-4059
-
-
Taylor, C.T.1
-
42
-
-
0038308573
-
Tumor necrosis factor-α causes accumulation of a ubiquitinated form of hypoxia inducible factor-1α through a nuclear factor-κB-dependent pathway
-
Zhou J, Schmid T, Brune B. Tumor necrosis factor-α causes accumulation of a ubiquitinated form of hypoxia inducible factor-1α through a nuclear factor-κB-dependent pathway. Mol Biol Cell. 2003;14:2216-2225.
-
(2003)
Mol Biol Cell.
, vol.14
, pp. 2216-2225
-
-
Zhou, J.1
Schmid, T.2
Brune, B.3
-
43
-
-
45349097483
-
Regulation of hypoxia-inducible factor-1α by NF-κB
-
van Uden P, Kenneth NS, Rocha S. Regulation of hypoxia-inducible factor-1α by NF-κB. Biochem J. 2008;412:477-484.
-
(2008)
Biochem J.
, vol.412
, pp. 477-484
-
-
Van Uden, P.1
Kenneth, N.S.2
Rocha, S.3
-
44
-
-
44849100198
-
NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF- 1α
-
Rius J, Guma M, Schachtrup C, et al. NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF- 1α. Nature. 2008;453:807-811.
-
(2008)
Nature.
, vol.453
, pp. 807-811
-
-
Rius, J.1
Guma, M.2
Schachtrup, C.3
-
45
-
-
37049002653
-
Hypoxia up-regulates hypoxia-inducible factor-1α transcription by involving phosphatidylinositol 3-kinase and nuclear factor κb in pulmonary artery smooth muscle cells
-
Belaiba RS, Bonello S, Zahringer C, et al. Hypoxia up-regulates hypoxia-inducible factor-1α transcription by involving phosphatidylinositol 3-kinase and nuclear factor κB in pulmonary artery smooth muscle cells. Mol Biol Cell. 2007;18:4691-4697.
-
(2007)
Mol Biol Cell.
, vol.18
, pp. 4691-4697
-
-
Belaiba, R.S.1
Bonello, S.2
Zahringer, C.3
-
46
-
-
58349102711
-
Overexpression of von Hippel-Lindau protein in skeletal muscles of patients with chronic obstructive pulmonary disease
-
Jatta K, Eliason G, Portela-GomesGM, et al. Overexpression of von Hippel-Lindau protein in skeletal muscles of patients with chronic obstructive pulmonary disease. J Clin Pathol. 2009;62:70-76.
-
(2009)
J Clin Pathol.
, vol.62
, pp. 70-76
-
-
Jatta, K.1
Eliason, G.2
Portela-Gomes, G.M.3
-
47
-
-
84867867477
-
The nuclear factor κb signaling pathway: Integrating metabolism with inflammation
-
Tornatore L, Thotakura AK, Bennett J, MorettiM, Franzoso G. The nuclear factor κB signaling pathway: integrating metabolism with inflammation. Trends Cell Biol. 2012;22:557-566.
-
(2012)
Trends Cell Biol.
, vol.22
, pp. 557-566
-
-
Tornatore, L.1
Thotakura, A.K.2
Bennett, J.3
Moretti, M.4
Franzoso, G.5
-
48
-
-
2942662046
-
NF-κBactivation and iNOS upregulation in skeletal muscle of patients with COPD and low body weight
-
Agusti A, MorlaM, Sauleda J, Saus C, Busquets X. NF-κBactivation and iNOS upregulation in skeletal muscle of patients with COPD and low body weight. Thorax. 2004;59:483-487.
-
(2004)
Thorax.
, vol.59
, pp. 483-487
-
-
Agusti, A.1
Morla, M.2
Sauleda, J.3
Saus, C.4
Busquets, X.5
|