Female PAPP-A knockout mice are resistant to metabolic dysfunction induced by high-fat/high-sucrose feeding at middle age

Age

Volumn 37, Issue 3, 2015, Pages 1-14

  Hill, Cristal M ^a   Arum, Oge ^a,c   Boparai, Ravneet K ^a   Wang, Feiya ^a   Fang, Yimin ^a   Sun, Liou Y ^a   Masternak, Michal M ^b   Bartke, Andrzej ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

^c Geriatrics Research Laboratory Department of Internal Medicine Southern Illinois University School of Medicine ^*  (United States)

Author keywords

High fat high sucrose diet; Immune response; Insulin IGF 1 signaling; Longevity; Metabolic flexibility; PAPP A KO mice

Indexed keywords

ADIPONECTIN; CYTOKINE; INTERLEUKIN 2; INTERLEUKIN 6; PREGNANCY ASSOCIATED PLASMA PROTEIN A; SOMATOMEDIN BINDING PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; INSULIN; INTERLEUKIN 4; SOMATOMEDIN C; SUCROSE; TUMOR NECROSIS FACTOR;

ADULT; AGING; ANIMAL EXPERIMENT; ARTICLE; BIOACCUMULATION; BODY WEIGHT; CALORIMETRY; CARBOHYDRATE DIET; CONTROLLED STUDY; DIETARY INTAKE; FEMALE; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; INSULIN SENSITIVITY; LIPID DIET; MALE; METABOLIC DISORDER; MIDDLE AGED; MOUSE; NONHUMAN; OBESITY; OXYGEN CONSUMPTION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SUGAR INTAKE; WEIGHT GAIN; ANIMAL; BLOOD; BREATHING RATE; DEFICIENCY; ENERGY METABOLISM; INDIRECT CALORIMETRY; KNOCKOUT MOUSE; LONGEVITY; METABOLISM; PHENOTYPE; PHYSIOLOGY;

ADIPONECTIN; ANIMALS; CALORIMETRY, INDIRECT; DIET, HIGH-FAT; ENERGY METABOLISM; INSULIN; INSULIN-LIKE GROWTH FACTOR I; INTERLEUKIN-2; INTERLEUKIN-4; INTERLEUKIN-6; LONGEVITY; MICE; MICE, KNOCKOUT; OXYGEN CONSUMPTION; PHENOTYPE; PREGNANCY-ASSOCIATED PLASMA PROTEIN-A; RESPIRATORY RATE; SUCROSE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84928998042     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-015-9765-1     Document Type: Article

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