Preferential impact of pregnancy-associated plasma protein-A deficiency on visceral fat in mice on high-fat diet

American Journal of Physiology - Endocrinology and Metabolism

Volumn 305, Issue 9, 2013, Pages

  Conover, Cheryl A ^a   Harstad, Sara L ^a   Tchkonia, Tamar ^a   Kirkland, James L ^a  

^a MAYO CLINIC   (United States)

Author keywords

Adipose tissue; Mesenteric fat

Indexed keywords

INSULIN RECEPTOR; MESSENGER RNA; PREGNANCY ASSOCIATED PLASMA PROTEIN A; PROTEIN KINASE B; SOMATOMEDIN C;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CELL COUNT; CELL SIZE; ENZYME PHOSPHORYLATION; FEMALE; IN VIVO STUDY; INTRAABDOMINAL FAT; KNOCKOUT MOUSE; LIPID DIET; LIPID STORAGE; LIPID TRANSPORT; MALE; MOUSE; NONHUMAN; PREGNANCY ASSOCIATED PLASMA PROTEIN A DEFICIENCY; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WILD TYPE;

ADIPOSE TISSUE; MESENTERIC FAT;

ADIPOCYTES; ANIMALS; BLOTTING, WESTERN; CELL COUNT; CELL SIZE; DIET, HIGH-FAT; FEMALE; GENE EXPRESSION; GLUCOSE TOLERANCE TEST; INSULIN RESISTANCE; INTRA-ABDOMINAL FAT; LIPID METABOLISM; MICE; MICE, INBRED C57BL; OBESITY; PREGNANCY; PREGNANCY-ASSOCIATED PLASMA PROTEIN-A; REAL-TIME POLYMERASE CHAIN REACTION; RNA;

EID: 84887013429     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00405.2013     Document Type: Article

References (35)

1. Back K, Arnqvist HJ. Changes in insulin and IGF-I receptor expression during differentiation of human preadipocytes. Growth Horm IGF Res 19: 101-111, 2009.
2. Back K, Brannmark C, Stralfors P, Arnqvist HJ. Differential effects of IGF-I, IGF-II and insulin in human preadipocytes and adipocytes: role of insulin and IGF-I receptors. Mol Cell Endocrinol 339: 130-135, 2011.
3. Baxter RC, Twigg SM. Actions of IGF binding proteins and related proteins in adipose tissue. Trends Endocrinol Metab 20: 49-505, 2009.
4. Bayes-Genis A, Conover CA, Overgaard MT, Bailey KR, Christiansen M, Holmes DR Jr, Virmani R, Oxvig C, Schwartz RS. Pregnancyassociated plasma protein A as a marker of acute coronary syndromes. N Engl J Med 345: 1022-1029, 2001.
5. Berryman DE, List EO, Palmer AJ, Chung MU, Wright-Piekarski J, Lubbers E, O'Connor P, Okada S, Kopchick JJ. Two-year body composition analyses of long-lived GHR null mice. J Gerontol Biol Sci 65A: 31-40, 2010.
6. Bluher S, Kratzsch J, Kiess W. Insulin-like growth factor I, growth hormone and insulin in white adipose tissue. Best Pract Res Clin Endocrinol Metab 19: 577-587, 2005.
7. Bonaca MP, Scirica BM, Sabatine MS, Jarolim P, Murphy SA, Chamberlin JS, Rhodes DW, Southwick PC, Braunwald E, Morrow DA. Prospective evaluation of pregnancy-associated plasma protein-A and outcomes in patients with acute coronary syndromes. J Am Coll Cardiol 60: 332-338, 2012.
8. Catalano KJ, Stefanovski D, Bergman RN. Critical role of the mesenteric depot versus other intra-abdominal adipose depots in the development of insulin resistance in young rats. Diabetes 59: 1416-1423, 2010.
9. Cleveland-Donovan K, Maile LA, Tsiaras WG, Tchkonia T, Kirkland JL, Boney CM. IGF-I activation of the AKT pathway is impaired in visceral but not subcutaneous preadipocytes from obese subjects. Endocrinology 151: 3752-3763, 2010.
10. Collins FS. A view of the U.S. obesity epidemic. NIH Director's Blog November 7, 2012.
11. Conover CA. Key questions and answers about pregnancy-associated plasma protein-A. Trends Endocrinol Metab 23: 242-249, 2012.
12. Conover CA, Bale LK, Durham SK, Powell DR. Insulin-like growth factor (IGF) binding protein-3 potentiation of IGF action is mediated through the phosphatidylinositol-3-kinase pathway and is associated with alteration in protein kinase B/AKT sensitivity. Endocrinology 141: 3098-3103, 2000.
13. Conover CA, Bale LK, Overgaard MT, Johnstone EW, Laursen UH, Fuchtbauer EM, Oxvig C, van Deursen J. Metalloproteinase pregnancyassociated plasma protein A is a critical growth regulatory factor during fetal development. Development 131: 1187-1194, 2003.
14. Conover CA, Mason MA, Levine JA, Novak CM. Metabolic consequences of pregnancy-associated plasma protein-A deficiency in mice: exploring possible relationship to the longevity phenotype. J Endocrinol 198: 599-605, 2008.
15. Ding J, Hsu FC, Harris TB, Liu Y, Kritchevsky SB, Szklo M, Ouyang P, Espeland MA, Lohman KK, Criqui MH, Allison M, Bluemke DA, Carr JJ. The association of pericardial fat with incident coronary heart disease: the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Clin Nutr 90: 499-504, 2009.
16. Gealekman O, Guseva N, Hartigan C, Apotheker S, Gorgoglione M, Gurav K, Tran KV, Straubhaar J, Nicoloro S, Czech JP, Thompson M, Perugini RA, Corvera S. Depot-specific differences and insufficient subcutaneous adipose tissue angiogenesis in human obesity. Circulation 123: 186-194, 2011.
17. Harrington SC, Simari RD, Conover CA. Genetic deletion of pregnancy-associated plasma protein-A is associated with resistance to atherosclerotic lesion development in apolipoprotein E-deficient mice challenged with a high-fat diet. Circ Res 100: 1696-1702, 2007.
18. Jensen MD. Role of body fat distribution and the metabolic complications of obesity. J Clin Endocrinol Metab 93: S57-S63, 2008.
19. Kiselyov VV, Versteyhe S, Gauguin L, De Meyts P. Harmonic oscillator model of the insulin and IGF1 receptors' allosteric binding and activation. Mol Systems Biol 5: 243-254, 2009.
20. Li L, Ren W, Li J, Liu J, Wang L, Zheng X, Liu D, Li S, Souvenir R, Tang J. Increase in serum pregnancy-associated plasma protein-A is correlated with increase in cardiovascular risk factors in adult patients with growth hormone deficiency. Endocrine 42: 375-381, 2012.
21. Lumeng CN, Bodzin JL, Saltiel AR. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 117: 175-184, 2007.
22. th Ann Meet Endocr Soc Program and Abstracts Book. Chevy Chase, MD: Endocrine Society Press, Page 156, Abstract P1-8, 2007.
23. Perrini S, Leonardini A, Laviola L, Giorgino F. Biological specificity of visceral adipose tissue and therapeutic intervention. Arch Physiol Biochem 114: 277-286, 2008.
24. Romanski SA, Nelson RM, Jensen MD. Meal fatty acid uptake in human adipose tissue: technical and experimental design issues. Am J Physiol Endocrinol Metab 279: E447-E454, 2000.
25. Seale P, Kajimura S, Spiegelman BM. Transcriptional control of brown adipocyte development and physiological function of mice and men. Genes Dev 23: 788-797, 2009.
26. Tang SL, Chen WJ, Yin K, Zhao GJ, Mo ZC, Lv YC, Ouyang XP, Yu XH, Kuang HJ, Jiang ZS, Fu YC, Tang CK. PAPP-A negatively regulates ABCA1, ABCG1 and SR-B1 expression by inhibiting LXRβ through the IGF-I-mediated signaling pathway. Atherosclerosis 222: 344-354, 2012.
27. Tchkonia T, Giorgadze N, Pirtskhalava T, Tchoukalova Y, Karagiannides I, Forse RA, Deponte M, Stevenson M, Guo W, Han J, Waloga G, Lash TL, Jensen MD, Kirkland JL. Fat depot origin affects adipogenesis in primary cultured and cloned human preadipocytes. Am J Physiol Regul Integr Comp Physiol 282: R1286-R1296, 2002.
28. Tchkonia T, Lenburg M, Thomou T, Giorgadze N, Frampton G, Pirtskhalava T, Cartwright A, Cartwright M, Glanagan J, Karagiannides I, Gerry N, Forse A, Tchoukalova Y, Jensen MD, Pothoulakis C, Kirkland JL. Identification of depot-specific human fat cell progenitors through distinct expression profiles and developmental gene patterns. Am J Physiol Endocrinol Metab 292: E298-E307, 2007.
29. Tchkonia T, Thomou T, Zhu Y, Karagiannides I, Pothoulakis C, Jensen MD, Kirkland JL. Mechanisms and metabolic implications of regional differences among fat depots. Cell Metab 17: 644-656, 2013.
30. Tchoukalova YD, Nathanielsz PW, Conover CA, Smith S, Ravussin E. Regional variation in adipogenesis and IGF regulatory proteins in the fetal baboon. Biochem Biophys Res Commun 380: 679-683, 2009.
31. Tchoukalova YD, Votruba SB, Tchkonia T, Giorgadze N, Kirkland JL, Jensen MD. Regional differences in cellular mechanisms of adipose tissue gain with overfeeding. Proc Natl Acad Sci USA 107: 18226-18231, 2010.
32. Tran TT, Yamamoto Y, Gesta S, Kahn CR. Beneficial effects of subcutaneous fat transplantation on metabolism. Cell Metab 7: 410-420, 2008.
33. Villaret A, Galitzky Decaunes P, Esteve D, Marques MA, Sengenes C, Chiotasso P, Tchkonia T, Lafontan M, Kirkland JL, Bouloumie A. Adipose tissue endothelial cells from obese human subjects: differences among depots in angiogenic, metabolic, and inflammatory gene expression and cellular senescence. Diabetes 59: 2755-2763, 2010.
34. Wajchenberg BL. Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocr Rev 21: 697-738, 2000.
35. Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, Mori Y, Ide T, Murakami K, Tsuboyama-Kasaoka N, Ezaki O, Akanuma Y, Gavrilova O, Vinson C, Reitman ML, Kagechika H, Shudo K, Yoda M, Nakano Y, Tobe K, Nagai R, Kimura S, Tomita M, Froguel P, Kadowaki T. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 7: 941-946, 2001.