Mitochondrial ClpX activates a key enzyme for heme biosynthesis and erythropoiesis

Cell

Volumn 161, Issue 4, 2015, Pages 858-867

  Kardon, Julia R ^a   Yien, Yvette Y ^b   Huston, Nicholas C ^b   Branco, Diana S ^b   Hildick Smith, Gordon J ^b,c   Rhee, Kyu Y ^c   Paw, Barry H ^b,d   Baker, Tania A ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOLEVULINIC ACID; ENDOPEPTIDASE CLPX; HEME; HEMOGLOBIN; PYRIDOXAL 5 PHOSPHATE; SYNTHETASE; 5 AMINOLEVULINATE SYNTHASE; ALAS2 PROTEIN, HUMAN; AMINOLEVULINATE SYNTHASE, S CEREVISIAE; CHAPERONE; CLPX PROTEIN, HUMAN; ENDOPEPTIDASE CLP; MCX1 PROTEIN, S CEREVISIAE; MITOCHONDRIAL PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ERYTHROPOIESIS; GENE INTERACTION; IN VITRO STUDY; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; UPREGULATION; YEAST; ZEBRA FISH; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; CYTOLOGY; EUKARYOTE; EVOLUTION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT;

BACTERIA (MICROORGANISMS); EUKARYOTA; MAMMALIA; PROKARYOTA; VERTEBRATA;

5-AMINOLEVULINATE SYNTHETASE; AMINO ACID SEQUENCE; AMINOLEVULINIC ACID; ANIMALS; BIOLOGICAL EVOLUTION; ENDOPEPTIDASE CLP; ERYTHROPOIESIS; EUKARYOTA; HEME; HUMANS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MOLECULAR CHAPERONES; MOLECULAR SEQUENCE DATA; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; ZEBRAFISH;

EID: 84928966497     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2015.04.017     Document Type: Article

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