Key role for scavenger receptor B-I in the integrative physiology of host defense during bacterial pneumonia

Mucosal Immunology

Volumn 8, Issue 3, 2015, Pages 559-571

  Gowdy, K M ^a   Madenspacher, J H ^a   Azzam, K M ^a   Gabor, K A ^a   Janardhan, K S ^b,c   Aloor, J J ^a   Fessler, M B ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CORTICOSTERONE; CXCL2 CHEMOKINE; GRANULOCYTE COLONY STIMULATING FACTOR; LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; SCAVENGER RECEPTOR BI; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; L SELECTIN; SCARB1 PROTEIN, MOUSE; SCAVENGER RECEPTOR B;

ADRENAL FUNCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL PNEUMONIA; CELL COUNTING; CELL DEATH; CONTROLLED STUDY; CYTOKINE PRODUCTION; HEMATOPOIETIC CELL; HOST RESISTANCE; INNATE IMMUNITY; LACTATE DEHYDROGENASE BLOOD LEVEL; LUNG LAVAGE; MACROPHAGE; MALE; MORTALITY; MOUSE; NEUTROPHIL; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; REGULATORY MECHANISM; ADRENAL GLAND; ANIMAL; BACTERIAL LOAD; BIOSYNTHESIS; BONE MARROW CELL; DEFICIENCY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; KLEBSIELLA INFECTION; KLEBSIELLA PNEUMONIAE; KNOCKOUT MOUSE; LUNG; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS;

ADRENAL GLANDS; ANIMALS; ANTIGENS, CD11B; BACTERIAL LOAD; BONE MARROW CELLS; CORTICOSTERONE; CYTOKINES; GENE EXPRESSION REGULATION; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; L-SELECTIN; LIPOPOLYSACCHARIDES; LUNG; MALE; MICE; MICE, KNOCKOUT; NEUTROPHILS; PNEUMONIA, BACTERIAL; SCAVENGER RECEPTORS, CLASS B; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS;

EID: 84928922723     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2014.88     Document Type: Article

References (49)

1. Waterer, G.W., Rello, J. & Wunderink, R.G. Management of communityacquired pneumonia in adults. Am. J. Respir. Crit. Care Med. 183, 157-164 (2011).
2. Mizgerd, J.P. Respiratory infection and the impact of pulmonary immunity on lung health and disease. Am. J. Respir. Crit. Care Med. 186, 824-829 (2012).
3. Remmelts, H.H., Meijvis, S.C., Kovaleva, A., Biesma, D.H., Rijkers, G.T. & Heijligenberg, R. Changes in serum cortisol levels during communityacquired pneumonia: the influence of dexamethasone. Respir. Med. 106, 905-908 (2012).
4. Canton, J., Neculai, D. & Grinstein, S. Scavenger receptors in homeostasis and immunity. Nat. Rev. Immunol. 13, 621-634 (2013).
5. Qiu, Y. et al. Scavenger receptor A modulates the immune response to pulmonary Cryptococcus neoformans infection. J. Immunol. 191, 238-248 (2013).
6. Hollifield, M., Bou Ghanem, E., de Villiers, W.J. & Garvy, B.A. Scavenger receptor A dampens induction of inflammation in response to the fungal pathogen Pneumocystis carinii. Infect. Immun. 75, 3999-4005 (2007).
7. Arredouani, M. et al. The scavenger receptor MARCO is required for lung defense against pneumococcal pneumonia and inhaled particles. J. Exp. Med. 200, 267-272 (2004).
8. Acton, S., Rigotti, A., Landschulz, K.T., Xu, S., Hobbs, H.H. & Krieger, M. Identification of scavenger receptor SR-BI as a high density lipoprotein receptor. Science 271, 518-520 (1996).
9. Murphy, A.J. et al. Neutrophil activation is attenuated by high-density lipoprotein and apolipoprotein A-I in in vitro and in vivo models of inflammation. Arterioscler. Thromb. Vasc. Biol. 31, 1333-1341 (2011).
10. Bocharov, A.V. et al. Targeting of scavenger receptor class B type I by synthetic amphipathic alpha-helical-containing peptides blocks lipopolysaccharide (LPS)uptake and LPS-inducedpro-inflammatory cytokine responses in THP-1 monocyte cells. J. Biol. Chem. 279, 36072-36082 (2004).
11. Cai, L., Ji, A., de Beer, F.C., Tannock, L.R. & van der Westhuyzen, D.R. SRBI protects against endotoxemia in mice through its roles in glucocorticoid production and hepatic clearance. J. Clin. Invest. 118, 364-375 (2008).
12. Hoekstra, M., van der Sluis, R.J., Van Eck, M. & Van Berkel, T.J. Adrenalspecific scavenger receptor BI deficiency induces glucocorticoid insufficiency and lowers plasma very-low-density and low-density lipoprotein levels in mice. Arterioscler. Thromb. Vasc. Biol. 33, e39-e46 (2013).
13. McCarthy, J.J. et al. Association of genetic variants in the HDL receptor, SR-B1, with abnormal lipids in women with coronary artery disease. J. Med. Genet. 40, 453-458 (2003).
14. Vergeer, M. et al. Genetic variant of the scavenger receptor BI in humans. N. Engl. J. Med. 364, 136-145 (2011).
15. Sahin, F. & Yildiz, P. Distinctive biochemical changes in pulmonary tuberculosis and pneumonia. Arch. Med. Sci. 9, 656-661 (2013).
16. Deniz, O. et al. Serum HDL-C levels, log (TG/HDL-C) values and serum total cholesterol/HDL-C ratios significantly correlate with radiological extent of disease in patients with community-acquired pneumonia. Clin. Biochem. 39, 287-292 (2006).
17. Kolleck, I., Sinha, P. & Rustow, B. Vitamin E as an antioxidant of the lung: mechanisms of vitamin E delivery to alveolar type II cells. Am. J. Respir. Crit. Care Med. 166 (12 Pt 2), S62-S66 (2002).
18. Xu, S., Laccotripe, M., Huang, X., Rigotti, A., Zannis, V.I. & Krieger, M. Apolipoproteins of HDL can directly mediate binding to the scavenger receptor SR-BI, an HDL receptor that mediates selective lipid uptake. J. Lipid Res. 38, 1289-1298 (1997).
19. Madenspacher, J.H. et al. p53 Integrates host defense and cell fate during bacterial pneumonia. J. Exp. Med. 210, 891-904 (2013).
20. Mizgerd, J.P. Acute lower respiratory tract infection. N. Engl. J. Med. 358, 716-727 (2008).
21. Mizgerd, J.P., Peschon, J.J. & Doerschuk, C.M. Roles of tumor necrosis factor receptor signaling during murine Escherichia coli pneumonia. Am. J. Respir. Cell Mol. Biol. 22, 85-91 (2000).
22. Jeyaseelan, S. et al. Induction of CXCL5 during inflammation in the rodent lung involves activation of alveolar epithelium. Am. J. Respir. Cell Mol. Biol. 32, 531-539 (2005).
23. Vishnyakova, T.G. et al. Binding and internalization of lipopolysaccharide by Cla-1, a human orthologue of rodent scavenger receptor B1. J. Biol. Chem. 278, 22771-22780 (2003).
24. Baranova, I.N. et al. Class B scavenger receptor types I and II and CD36 mediate bacterial recognition and proinflammatory signaling induced by Escherichia coli, lipopolysaccharide, and cytosolic chaperonin 60. J. Immunol. 188, 1371-1380 (2012).
25. Gregory, S.H., Sagnimeni, A.J. & Wing, E.J. Bacteria in the bloodstream are trapped in the liver and killed by immigrating neutrophils. J. Immunol. 157, 2514-2520 (1996).
26. Caramori, G. & Adcock, I. Anti-inflammatory mechanisms of glucocorticoids targeting granulocytes. Curr. Drug Targets Inflamm. Allergy 4, 455-463 (2005).
27. Marik, P.E., Meduri, G.U., Rocco, P.R. & Annane, D. Glucocorticoid treatment in acute lung injury and acute respiratory distress syndrome. Crit. Care Clin. 27, 589-607 (2011).
28. Wu, Z., Sawamura, T., Kurdowska, A.K., Ji, H.L., Idell, S. & Fu, J. LOX-1 deletion improves neutrophil responses, enhances bacterial clearance, and reduces lung injury in a murine polymicrobial sepsis model. Infect. Immun. 79, 2865-2870 (2011).
29. Barth, H. et al. Scavenger receptor class B is required for hepatitis C virus uptake and cross-presentation by human dendritic cells. J. Virol. 82, 3466-3479 (2008).
30. Schafer, G., Guler, R., Murray, G., Brombacher, F. & Brown, G.D. The role of scavenger receptor B1 in infection with Mycobacterium tuberculosis in a murine model. PLoS ONE 4, e8448 (2009).
31. Rodrigues, C.D. et al. Host scavenger receptor SR-BI plays a dual role in the establishment of malaria parasite liver infection. Cell Host Microbe 4, 271-282 (2008).
32. Baranova, I.N. et al. Role of human CD36 in bacterial recognition, phagocytosis, and pathogen-induced JNK-mediated signaling. J. Immunol. 181, 7147-7156 (2008).
33. Triantafilou, M. et al. Lipopolysaccharides from atherosclerosis-associated bacteria antagonize TLR4, induce formation of TLR2/1/CD36 complexes in lipid rafts and trigger TLR2-induced inflammatory responses in human vascular endothelial cells. Cell Microbiol. 9, 2030-2039 (2007).
34. Yamamoto, K. et al. Roles of lung epithelium in neutrophil recruitment during pneumococcal pneumonia. Am. J. Respir. Cell Mol. Biol. 50, 253-262 (2013).
35. Liu, Y. et al. IL-17A and TNF-alpha exert synergistic effects on expression of CXCL5 by alveolar type II cells in vivo and in vitro. J. Immunol. 186, 3197-3205 (2011).
36. Haddad, J.J. Glutathione depletion is associated with augmenting a proinflammatory signal: evidence for an antioxidant/pro-oxidant mechanism regulating cytokines in the alveolar epithelium. Cytokines Cell Mol. Ther. 6, 177-187 (2000).
37. Hernandez, M.L. et al. Vitamin E, gamma-tocopherol, reduces airway neutrophil recruitment after inhaled endotoxin challenge in rats and in healthy volunteers. Free Radic. Biol. Med. 60, 56-62 (2013).
38. Carrasco-Marin, E. et al. LIMP-2 links late phagosomal trafficking with the onset of the innate immune response to Listeria monocytogenes: a role in macrophage activation. J. Biol. Chem. 286, 3332-3341 (2011).
39. Ishiguro, T. et al. Role of macrophage scavenger receptors in response to Listeria monocytogenes infection in mice. Am. J. Pathol. 158, 179-188 (2001).
40. Higuchi, H., Ito, E., Iwano, H., Oikawa, S. & Nagahata, H. Effects of vitamin E supplementation on cellular alpha-tocopherol concentrations of neutrophils in Holstein calves. Can. J. Vet. Res. 77, 120-125 (2013).
41. Hall, J.A. et al. Influence of dietary antioxidants and fatty acids on neutrophil mediated bacterial killing and gene expression in healthy Beagles. Vet. Immunol. Immunopathol. 139, 217-228 (2011).
42. Valacchi, G. et al. Lung vitamin E transport processes are affected by both age and environmental oxidants in mice. Toxicol. Appl. Pharmacol. 222, 227-234 (2007).
43. Valacchi, G. et al. Cigarette smoke exposure causes changes in Scavenger Receptor B1 level and distribution in lung cells. Int. J. Biochem. Cell Biol. 43, 1065-1070 (2011).
44. Kimura, T. et al. Induction of scavenger receptor class B type I is critical for simvastatin enhancement of high-density lipoprotein-induced antiinflammatory actions in endothelial cells. J. Immunol. 181, 7332-7340 (2008).
45. Zhang, Q., Ma, A.Z., Song, Z.Y., Wang, C. & Fu, X.D. Nifedipine enhances cholesterol efflux in RAW264.7 macrophages. Cardiovasc. Drugs Ther. 27, 425-431 (2013).
46. Lu, L. et al. Regulations of the key mediators in inflammation and atherosclerosis by aspirin in human macrophages. Lipids Health Dis. 9, 16 (2010).
47. Gantman, A., Fuhrman, B., Aviram, M. & Hayek, T. High glucose stimulates macrophage SR-BI expression and induces a switch in its activity from cholesterol efflux to cholesterol influx. Biochem. Biophys. Res. Commun. 391, 523-528 (2010).
48. Vickers, K.C., Palmisano, B.T., Shoucri, B.M., Shamburek, R.D. & Remaley, A.T. MicroRNAs are transported in plasmaand delivered to recipient cells by high-density lipoproteins. Nat. Cell Biol. 13, 423-433 (2011).
49. Liston, C. & Gan, W.B. Glucocorticoids are critical regulators of dendritic spine development and plasticity in vivo. Proc. Natl Acad. Sci. USA 108, 16074-16079 (2011).