Vitamin E as an antioxidant of the lung: Mechanisms of vitamin E delivery to alveolar type II cells

American Journal of Respiratory and Critical Care Medicine

Volumn 166, Issue 12 II, 2002, Pages

  Kolleck, Ingrid ^a   Sinha, Pranav ^a   Rüstow, Bernd ^a,b  

^a HUMBOLDT UNIVERSITY   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Alveolar type II cells; High density lipoprotein; Lung; Scavenger receptor BI; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; CHOLESTEROL; CUBILIN; DIPALMITOYLPHOSPHATIDYLCHOLINE; HIGH DENSITY LIPOPROTEIN; LIPID BINDING PROTEIN; LUNG SURFACTANT; MEGALIN; PHOSPHOLIPID DERIVATIVE; POLYUNSATURATED FATTY ACID; SCAVENGER RECEPTOR;

ACUTE DISEASE; ALPHA TOCOPHEROL DEFICIENCY; APOPTOSIS; CHRONIC DISEASE; CONFERENCE PAPER; HUMAN; HYPEROXIA; LIPID TRANSPORT; LIPOGENESIS; LUNG ALVEOLUS CELL TYPE 2; LUNG INJURY; NONHUMAN; PRIORITY JOURNAL;

EID: 0037115341     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/rccm.2206019     Document Type: Conference Paper

References (47)

1. Ehrenkranz RA, Ablow RC, Warshaw JB. Prevention of bronchopulmonary dysplasia with vitamin E administration during the acute stages of respiratory distress syndrome. J Pediatr 1979;95:873-878.
2. MacNee W, Rahman I. Oxidants and antioxidants as therapeutic targets in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999;160:S58-S65.
3. Cross CE, Van-der-Vliet A, O'Neill CA, Louie S, Halliwell B. Oxidants, antioxidants, and respiratory tract lining fluids. Environ Health Perspect 1994;102:10185-10191.
4. Chow CK. Vitamin E and oxidative stress. Free Radic Biol Med 1991;11:2:15-232.
5. Guthmann F, Haupt R, Schlame M, Stevens PA, Rustow B. Alveolar surfactant subfractions differ in their lipid composition. Int J Biochem Cell Biol 1995;27:1021-1026.
6. Rudiger M, von-Baehr A, Haupt R, Wauer RR, Rustow B. Preterm infants with high polyunsaturated fatty acid and plasmalogen content in tracheal aspirates develop bronchopulmonary dysplasia less often. Crit Care Med 2000;28:1572-1577.
7. Rustow B, Haupt R, Stevens PA, Kunze D. Type II pneumocytes secrete vitamin E together with surfactant lipids. Am J Physiol 1993;265:L133-L139.
8. Ingold KU, Webb AC, Witter D, Burton GW, Metcalfe TA, Muller DP. Vitamin E remains the major lipid-soluble, chain-breaking antioxidant in human plasma even in individuals suffering severe vitamin E deficiency. Arch Biochem Biophys 1987;259:224-225.
9. Chow CK, Airriess GR, Changchit C. Increased vitamin E content in the lungs of chronic cigarette-smoked rats. Ann NY Acad Sci 1989;570:425-427.
10. Elsayed NM. Antioxidant mobilization in response to oxidative stress: A dynamic environmental-nutritional interaction. Nutrition 2001;17:828-834.
11. Schünemann HJ, Grant BJB, Freudenheim JL, Muti P, Brown RW, Drake LA, Klocke RA, Trevisan M. The relation of serum levels of antioxidant vitamins C and E, retinal and carotinoids with pulmonary function in the general population. Am J Respir Crit Care Med 2001;163:1246-1255.
12. Taylor CG, McCutchon TL, Boermans HJ, DiSilvestro RA, Bray TM. Comparison of Zn and vitamin E for protection against hyperoxiainduced lung damage. Free Radic Biol Med 1997;22:543-550.
13. Tolle A, Kolleck I, Schlame M, Wauer R, Stevens PA, Rustow B. Effect of hyperoxia on the composition of the alveolar surfactant and the turnover of surfactant phospholipids, cholesterol, plasmalogens and vitamin E. Biochim Biophys Acta 1997;1346:198-204.
14. Jehle R, Schlame M, Buttner C, Frey B, Sinha P, Rustow B. Platelet-activating factor (PAF)-acetylhydrolase and PAF-like compounds in the lung: Effects of hyperoxia. Biochim Biophys Acta 2001;1532:60-66.
15. Henderson WR, Lu J, Poole KM, Dietsch GN, Chi EY. Recombinant human platelet-activating factor-acetylhydrolase inhibits airway inflammation and hyperreactivity in mouse asthma model. J Immunol 2000;164:3360-3367.
16. Traber MG, Kayden HJ. Vitamin E is delivered to cells via the high affinity receptor for low-density lipoprotein. Am J Clin Nutr 1984;40:747-751.
17. Guthmann F, Harrach RB, Looman AC, Stevens PA, Robenek H, Rustow B. Interaction of lipoproteins with type II pneumocytes in vitro: Morphological studies, uptake kinetics and secretion rate of cholesterol. Eur J Cell Biol 1997;74:197-207.
18. Voyno YT, Dobbs LG, Erickson SK, Hamilton RL. Low density lipoprotein- and high density lipoprotein-mediated signal transduction and exocytosis in alveolar type II cells. Proc Natl Acad Sci USA 1993;90:4256-4260.
19. Zheng G, Bachinsky DR, Stamenkovic I, Strickland DK, Brown D, Andres G, McCluskey RT. Organ distribution in rats of two members of the low-density lipoprotein receptor gene family, gp330 and LRP/alpa 2MR, and the receptor-associated protein (RAP). J Histochem Cytochem 1994;42:531-542.
20. Kounnas MZ, Haudenschild CC, Strickland DK, Argraves WS. Immunological localization of glycoprotein 330, low density lipoprotein receptor related protein and 39 kDa receptor associated protein in embryonic mouse tissues. In Vivo 1994;8:343-351.
21. Kolleck I, Schlame M, Fechner H, Looman AC, Wissel H, Rustow B. HDL is the major source of vitamin E for type II pneumocytes. Free Radic Biol Med 1999;27:882-890.
22. Luc G, Maid Z, Poulain P, Elkhalil L, Fruchart JC. Interstitial fluid apolipoprotein A-II: An association with the occurrence of myocardial infarction. Atherosclerosis 1996;127:131-137.
23. Ghalim N, Adlouni A, Saile R, Parra HJ, Benslimane A, Bard JM, Fruchart JC. Apolipoprotein AIV of human interstitial fluid is associated with apolipoprotein AI-containing but not with AII-containing particles. Int J Clin Lab Res 1996;26:224-228.
24. Krieger M. The "best" of cholesterols, the "worst" of cholesterols: A tale of two receptors. Proc Natl Acad Sci USA 1998;95:4077-4080.
25. Witt W, Kolleck I, Fechner H, Sinha P, Rustow B. Regulation by vitamin E of the scavenger receptor BI in rat liver and HepG2 cells. J Lipid Res 2000;41:2009-2016.
26. Lutton C, Fidge N. Distribution of high density lipoprotein binding proteins among various tissues in the rat. C R Acad Sci III 1994;317:731-735.
27. Witt W, Kolleck I, Rustow B. Identification of high density lipoprotein-binding proteins, including a glycosyl phosphatidylinositol-anchored membrane dipeptidase, in rat lung and type II pneumocytes. Am J Respir Cell Mol Biol 2000;22:739-746.
28. Moestrup SK, Kozyraki R, Kristiansen M, Kaysen JH, Rasmussen HH, Brault D, Pontillon F, Goda FO, Christensen EI, Hammond TG, et al. The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins. J Biol Chem 1998;273:5235-5242.
29. Hammad SM, Barth JL, Knaak C, Argraves WS. Megalin acts in concert with cubilin to mediate endocytosis of high density lipoproteins. J Biol Chem 2000;275:12003-12008.
30. Kolleck I, Wissel H, Guthmann F, Schlame M, Sinha P, Rüstow B. HDL-holoparticle uptake by alveolar type II cells: Effect of vitamin E status. Am J Respir Cell Mol Biol 2002;27:57-63.
31. Traber MG, Sokol RJ, Kohlschutter A, Yokota T, Muller DP, Dufour R, Kayden HJ. Impaired discrimination between stereoisomers of alpha-tocopherol in patients with familial isolated vitamin E deficiency. J Lipid Res 1993;34:201-210.
32. Traber MG, Sies H. Vitamin E in humans: Demand and delivery. Annu Rev Nutr 1996;16321-47:47.
33. Chan DK, Lim MS, Choo SH, Tan IK. Vitamin E status of infants at birth. J Perinat Med 1999;27:395-398.
34. Farrell PM. Vitamin E deficiency in premature infants. J Pediatr 1979;95:869-872.
35. Saugstad OD. Update on oxygen radical disease in neonatology. Curr Opin Obstet Gynecol 2001;13:147-153.
36. Beharka A, Redican S, Leka L, Meydani SN. Vitamin E status and immune function. Methods Enzymol 1997;282:247-263.
37. Beck MA. The influence of antioxidant nutrients on viral infection. Nutr Rev 1998;56:S140-S146.
38. Topbas ÖF, Jehle R, Sinha P, Rustow B, An electrophoretic study of vitamin E status and expression of heat shock proteins in alveolar type II and liver cells. Electrophoresis 2000;21:3552-3557.
39. Sabat R, Kolleck I, Witt W, Volk H, Sinha P, Rustow B. Immunological dysregulation of lung cells in response to vitamin E deficiency. Free Radic Biol Med 2001;30:1145-1153.
40. Sinha P, Kolleck I, Volk HD, Schlame M, Rüstow B. Vitamin E deficiency sensitizes alveolar type II cells for apoptosis. Biochim Biophys Acta 2002;1583:91-98.
41. Kelly FJ, Rodgers W, Handel J, Smith S, Hall MA. Time course of vitamin E repletion in the premature infant. Br J Nutr 1990;63:631-638.
42. Kolleck I, Witt W, Wissel H, Sinha P, Rustow B. HDL and vitamin E in plasma and the expression of SR-BI on lung cells during rat perinatal development. Lung 2000;178:191-200.
43. Wyne KL, Woollett LA. Transport of maternal LDL and HDL to the fetal membranes and placenta of the Golden Syrian hamster is mediated by receptor-dependent and receptor-independent processes. J Lipid Res 1998;39:518-530.
44. Bendich A, Gabriel E, Machlin LJ. Dietary vitamin E requirement for optimum immune responses in the rat. J Nutr 1986;116:675-681.
45. Jain SK, Wise R, Bocchini JJ. Vitamin E and vitamin E-quinone levels in red blood cells and plasma of newborn infants and their mothers. J Am Coll Nutr 1996;15:44-48.
46. Azzi A, Breyer I, Feher M, Ricciarelli R, Stocker A, Zimmer S, Zingg J. Nonantioxidant functions of alpha-tocopherol in smooth muscle cells. J Nutr 2001;131:378S-381S.
47. Zimmer S, Stocker A, Sarbolouki MN, Spycher SE, Sassoon J, Azzi A. A novel human tocopherol-associated protein: Cloning, in vitro expression, and characterization. J Biol Chem 2000;275:25672-25680.