Blockade of P2X7 receptors or pannexin-1 channels similarly attenuates postischemic damage

Journal of Cerebral Blood Flow and Metabolism

Volumn 35, Issue 5, 2015, Pages 843-850

  Cisneros Mejorado, Abraham ^a   Gottlieb, Miroslav ^a,b   Cavaliere, Fabio ^a,c   Magnus, Tim ^d   Koch Nolte, Friederich ^d   Scemes, Eliana ^e   Pérez Samartín, Alberto ^a,c   Matute, Carlos ^a,c  

^a ACHUCARRO BASQUE CENTER FOR NEUROSCIENCE   (Spain)

^b Center of Excellence for Brain Research   (Slovakia)

^c UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^e ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

ATP; excitotoxicity; P2X7 receptors; Panx1; postanoxic depolarization

Indexed keywords

3 [[5 (2,3 DICHLOROPHENYL) 1H TETRAZOL 1 YL]METHYL]PYRIDINE; ADENOSINE TRIPHOSPHATE; CARBENOXOLONE; ION CHANNEL; MEFLOQUINE; PANNEXIN 1; PROBENECID; PURINERGIC P2X RECEPTOR ANTAGONIST; PURINERGIC P2X7 RECEPTOR; UNCLASSIFIED DRUG; GAP JUNCTION PROTEIN; NERVE PROTEIN; PANNEXIN 1, RAT; PANX1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN CELL CULTURE; BRAIN DAMAGE; BRAIN HISTOLOGY; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN SLICE; CELL DEATH; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; ION CURRENT; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL MEMBRANE STEADY POTENTIAL; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN; CELL CULTURE; CELL HYPOXIA; DISEASE MODEL; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; METABOLISM; NERVE CELL; PATHOLOGY; RAT; SIGNAL TRANSDUCTION;

ANIMALS; BRAIN; BRAIN ISCHEMIA; CELL DEATH; CELL HYPOXIA; CELLS, CULTURED; CONNEXINS; DISEASE MODELS, ANIMAL; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NEURONS; PURINERGIC P2X RECEPTOR ANTAGONISTS; RATS; RECEPTORS, PURINERGIC P2X7; SIGNAL TRANSDUCTION;

EID: 84928827083     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2014.262     Document Type: Article

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