Pkd1 mono-allelic knockout is sufficient to trigger renal cystogenesis in a mini-pig model

International Journal of Biological Sciences

Volumn 11, Issue 4, 2015, Pages 361-369

  He, Jin ^a   Li, Qiuyan ^a   Fang, Suyun ^a   Guo, Ying ^a   Liu, Tongxin ^a   Ye, Jianhua ^a   Yu, Zhengquan ^a   Zhang, Ran ^a   Zhao, Yaofeng ^a   Hu, Xiaoxiang ^a   Bai, Xueyuan ^b   Chen, Xiangmei ^b   Li, Ning ^a,c  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

^c YUNNAN AGRICULTURAL UNIVERSITY   (China)

Author keywords

ADPKD; Disease model; PKD1; ZFN

Indexed keywords

ANIMALIA; RODENTIA; SUIDAE;

POLYCYSTIC KIDNEY DISEASE 1 PROTEIN; POLYCYSTIN;

ALLELE; ANIMAL; GENETICS; KIDNEY; KIDNEY POLYCYSTIC DISEASE; METABOLISM; PATHOLOGY; PIG; TRANSGENIC ANIMAL;

ALLELES; ANIMALS; ANIMALS, GENETICALLY MODIFIED; KIDNEY; POLYCYSTIC KIDNEY, AUTOSOMAL DOMINANT; SWINE; TRPP CATION CHANNELS;

EID: 84928810901     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.10858     Document Type: Article

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