Methylophiopogonanone a protects against cerebral ischemia/reperfusion injury and attenuates blood-brain barrier disruption

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Lin, Mingbao ^a   Sun, Wei ^b   Gong, Wan ^c   Zhou, Zhiyu ^d   Ding, Yasi ^a   Hou, Qi ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^d JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CLAUDIN 3; CLAUDIN 5; GELATINASE B; INTERCELLULAR ADHESION MOLECULE 1; METHYLOPHIOPOGONANONE A; NEUROPROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; 1,3 BENZODIOXOLE DERIVATIVE; ISOFLAVONE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CELL ACTIVATION; CELL DIFFERENTIATION; CELL SURVIVAL; CELL VIABILITY; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DOSE RESPONSE; ENZYME RELEASE; ENZYME REPRESSION; IN VITRO STUDY; LEUKOCYTE ADHERENCE; MALE; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; SURVIVAL TIME; WEIGHT REDUCTION; ANIMAL; CELL ADHESION; CELL LINE; COMPLICATION; DRUG EFFECTS; HUMAN; INFARCTION, MIDDLE CEREBRAL ARTERY; LEUKOCYTE; METABOLISM; MOUSE; PATHOLOGY; PHYSIOLOGY; PRECLINICAL STUDY; SPRAGUE DAWLEY RAT; VASCULAR ENDOTHELIUM;

ANIMALIA; OPHIOPOGON JAPONICUS; RATTUS;

ANIMALS; BENZODIOXOLES; BLOOD-BRAIN BARRIER; CELL ADHESION; CELL LINE; DRUG EVALUATION, PRECLINICAL; ENDOTHELIUM, VASCULAR; HUMANS; INFARCTION, MIDDLE CEREBRAL ARTERY; ISOFLAVONES; LEUKOCYTES; MALE; MICE; NEUROPROTECTIVE AGENTS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY;

EID: 84928806326     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0124558     Document Type: Article

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