Anti-inflammatory homoisoflavonoids from the tuberous roots of Ophiopogon japonicus

Fitoterapia

Volumn 83, Issue 6, 2012, Pages 1042-1045

  Li, Ning ^a   Zhang, Jia Yu ^a   Zeng, Ke Wu ^a   Zhang, Liang ^a   Che, Yan Yun ^a   Tu, Peng Fei ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Anti inflammatory; Homoisoflavonoids; Inhibitory effects of nitric oxide production; Ophiopogon japonicus; Ophiopogonanone H; Ophiopogonone E

Indexed keywords

ISOFLAVONOID; LIPOPOLYSACCHARIDE; NITRIC OXIDE; OPHIOPOGON ROOT; OPHIOPOGONANONE H; OPHIOPOGONONE E; QUERCETIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; IC 50; MICROGLIA; MOUSE; NONHUMAN; OPHIOPOGON JAPONICUS; PHYTOCHEMISTRY; PRIORITY JOURNAL; SPECTROSCOPY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; INFLAMMATION; INHIBITORY CONCENTRATION 50; ISOFLAVONES; LIPOPOLYSACCHARIDES; MICE; MICROGLIA; MOLECULAR STRUCTURE; NITRIC OXIDE; OPHIOPOGON; PHYTOTHERAPY; PLANT EXTRACTS; PLANT TUBERS;

MURINAE; OPHIOPOGON JAPONICUS;

EID: 84863987076     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2012.05.011     Document Type: Article

References (20)

1. Flora of China Editorial Committee of Chinese Academy of Sciences, Flora of China 1978 Science Press Beijing 130 164
2. C.L. Duan, Y.J. Li, P. Li, Y. Jiang, J.X. Liu, and P.F. Tu Spirostanol saponins from the fibrous roots of Ophiopogon japonicus (THUNB.) Ker-Gawl Helv Chim Acta 93 2010 227 232
3. Y.F. Zhou, J. Qi, D.N. Zhu, and B.Y. Yu Two new steroidal glycosides from Ophiopogon japonicus Chin Chem Lett 19 2008 1086 1088
4. Z.H. Cheng, T. Wu, L.Z. Li, N. Liu, B.Y. Yu, and L.S. Xu Studies on the liposoluble components from tuber of Ophiopogon japonicus Chin Pharm J 40 2005 337 341 (Pubitemid 40686437)
5. N.T.H. Anh, T. Van Sung, A. Porzel, K. Franke, and L.A. Wessjohann Homoisoflavonoids from Ophiopogon japonicus Ker-Gawler Phytochemistry 62 2003 1153 1158
6. N. Kaneda, H. Nakanishi, T. Kuraishi, and T. Katori Studies on the components of Ophiopogon roots (China). I Yakugaku Zasshi 103 1983 1133 1139
7. A. Tada, R. Kasai, T. Saitoh, and J. Shoji Studies on the constituents of Ophiopogonis tuber. V. Isolation of a novel class of homoisoflavonoids and determination of their structures. 1 Chem Pharm Bull 28 1980 1477 1484
8. A. Tada, R. Kasai, T. Saitoh, and J. Shoji Studies on the constituents of Ophiopogonis tuber. VI. Structures of homoisoflavonoids. (2) Chem Pharm Bull 28 1980 2039 2044
9. T. Asano, T. Murayama, Y. Hirai, and J. Shoji Comparative studies on the constituents of Ophiopogonis tuber and its congeners. VII. Studies on the homoisoflavonoids of the subterranean part of Ophiopogon japonicus Ker-Gawler cv. Nanus. (1) Chem Pharm Bull 41 1993 391 393 (Pubitemid 23128211)
10. T.M. Hung, V.T. Cao, T.D. Nguyen, S.W. Ryoo, J.H. Lee, and J.C. Kim Homoisoflavonoid derivatives from the roots of Ophiopogon japonicus and their in vitro anti-inflammation activity Bioorg Med Chem Lett 20 2010 2412 2416
11. M.S. Mulligan, J.M. Hevel, M.A. Marletta, and P.A. Ward Tissue injury caused by deposition of immune complexes is L-arginine dependent Proc Natl Acad Sci U S A 88 1991 6338 6342 (Pubitemid 21914941)
12. K.D. Kroncke, K. Fehsel, and V. Kolb-Bachofen Inducible nitric oxide synthase in human diseases Clin Exp Immunol 113 1998 147 156 (Pubitemid 28352831)
13. S. Moncada, and E.A. Higgs Molecular mechanisms and therapeutic strategies related to nitric oxide FASEB J 9 1995 1319 1330
14. C.C. Chao, S.X. Hu, T.W. Molitor, E.G. Shaskan, and P.K. Peterson Activated microglia mediate neuronal cell injury via a nitric oxide mechanism J Immunol 149 1992 2736 2741
15. M.J. Wang, W.W. Lin, H.L. Chen, Y.H. Chang, H.C. Ou, and J.S. Kuo Silymarin protects dopaminergic neurons against lipopolysaccharide-induced neurotoxicity by inhibiting microglia activation Eur J Neurosci 16 2002 2103 2112
16. J. Xu, D.Q. Jin, P. Zhao, X.Q. Song, Z.P. Sun, and Y.Q. Guo Sesquiterpenes inhibiting NO production from Celastrus orbiculatus Fitoterapia 2012 10.1016/j.fitote.2011.12.026
17. H. Zhang, F. Yang, J. Qi, X.C. Song, Z.F. Hu, and D.N. Zhu Homoisoflavonoids from the fibrous roots of polygonatum odoratum with glucose uptake-stimulatory activity in 3T3-L1 adipocytes J Nat Prod 73 2010 548 552
18. Y. Watanabe, S. Sanada, Y. Ida, and J. Shoji Comparative studies on the constituents of ophiopogonis tuber and its congeners. IV. Studies on the homoisoflavonoids of the subterranean part of Ophiopogon ohwii Okuyama and O. jaburan (Kunth) Lodd Chem Pharm Bull 33 1985 5358 5363 (Pubitemid 16184027)
19. A.T. Nguyen, J. Fontaine, H. Malonne, and P. Duez Homoisoflavanones from Disporopsis aspera Phytochemistry 67 2006 2159 2163 (Pubitemid 44344759)
20. J.C. Hernandez, F. Leon, F. Estevez, J. Quintana, and J. Bermejo A homo-isoflavonoid and a cytotoxic saponin from Dracaena draco Chem Biodivers 3 2006 62 68 (Pubitemid 43154286)