메뉴 건너뛰기




Volumn 6, Issue , 2015, Pages

A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells

(25)  Cook, Peter C a   Owen, Heather c   Deaton, Aimée M b   Borger, Jessica G c   Brown, Sheila L a   Clouaire, Thomas b   Jones, Gareth Rhys a   Jones, Lucy H c   Lundie, Rachel J c   Marley, Angela K c   Morrison, Vicky L d   Phythian Adams, Alexander T a   Wachter, Elisabeth b   Webb, Lauren M a   Sutherland, Tara E c   Thomas, Graham D c   Grainger, John R a   Selfridge, Jim b   McKenzie, Andrew N J e   Allen, Judith E c   more..


Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; ANTIGEN; METHYL CPG BINDING PROTEIN 2; DNA BINDING PROTEIN; MBD2 PROTEIN, MOUSE; MESSENGER RNA;

EID: 84928805959     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7920     Document Type: Article
Times cited : (65)

References (70)
  • 1
    • 84875528275 scopus 로고    scopus 로고
    • The dendritic cell lineage: Ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting
    • Merad, M., Sathe, P., Helft, J., Miller, J. & Mortha, A. The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting. Annu. Rev. Immunol. 31, 563-604 (2013).
    • (2013) Annu. Rev. Immunol , vol.31 , pp. 563-604
    • Merad, M.1    Sathe, P.2    Helft, J.3    Miller, J.4    Mortha, A.5
  • 2
    • 0348135024 scopus 로고    scopus 로고
    • Dendritic-cell control of pathogen-driven T-cell polarization
    • Kapsenberg, M. L. Dendritic-cell control of pathogen-driven T-cell polarization. Nat. Rev. Immunol. 3, 984-993 (2003).
    • (2003) Nat. Rev. Immunol , vol.3 , pp. 984-993
    • Kapsenberg, M.L.1
  • 3
    • 84857872834 scopus 로고    scopus 로고
    • Cellular networks controlling Th2 polarization in allergy and immunity
    • Kool, M., Hammad, H. & Lambrecht, B. N. Cellular networks controlling Th2 polarization in allergy and immunity. F1000 Biol. Rep. 4, 6 (2012).
    • (2012) F1000 Biol. Rep , vol.4 , pp. 6
    • Kool, M.1    Hammad, H.2    Lambrecht, B.N.3
  • 4
    • 84864345639 scopus 로고    scopus 로고
    • New paradigms in type 2 immunity
    • Pulendran, B. & Artis, D. New paradigms in type 2 immunity. Science 337, 431-435 (2012).
    • (2012) Science , vol.337 , pp. 431-435
    • Pulendran, B.1    Artis, D.2
  • 5
    • 84880923555 scopus 로고    scopus 로고
    • Type 2 immunity and wound healing: Evolutionary refinement of adaptive immunity by helminths
    • Gause, W. C., Wynn, T. A. & Allen, J. E. Type 2 immunity and wound healing: evolutionary refinement of adaptive immunity by helminths. Nat. Rev. Immunol. 13, 607-614 (2013).
    • (2013) Nat. Rev. Immunol , vol.13 , pp. 607-614
    • Gause, W.C.1    Wynn, T.A.2    Allen, J.E.3
  • 6
    • 77957745031 scopus 로고    scopus 로고
    • Inflammatory dendritic cells-not basophils-are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen
    • Hammad, H. et al. Inflammatory dendritic cells-not basophils-are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen. J. Exp. Med. 207, 2097-2111 (2010).
    • (2010) J. Exp. Med , vol.207 , pp. 2097-2111
    • Hammad, H.1
  • 7
    • 77957020655 scopus 로고    scopus 로고
    • Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths
    • Ohnmacht, C. et al. Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths. Immunity 33, 364-374 (2010).
    • (2010) Immunity , vol.33 , pp. 364-374
    • Ohnmacht, C.1
  • 8
    • 77957731193 scopus 로고    scopus 로고
    • CD11c depletion severely disrupts Th2 induction and development in vivo
    • Phythian-Adams, A. T. et al. CD11c depletion severely disrupts Th2 induction and development in vivo. J. Exp. Med. 207, 2089-2096 (2010).
    • (2010) J. Exp. Med , vol.207 , pp. 2089-2096
    • Phythian-Adams, A.T.1
  • 9
    • 38749095928 scopus 로고    scopus 로고
    • Alarming dendritic cells for Th2 induction
    • MacDonald, A. S. & Maizels, R. M. Alarming dendritic cells for Th2 induction. J. Exp. Med. 205, 13-17 (2008).
    • (2008) J. Exp. Med , vol.205 , pp. 13-17
    • Macdonald, A.S.1    Maizels, R.M.2
  • 10
    • 77954932467 scopus 로고    scopus 로고
    • Programming dendritic cells to induce T(H)2 and tolerogenic responses
    • Pulendran, B., Tang, H. & Manicassamy, S. Programming dendritic cells to induce T(H)2 and tolerogenic responses. Nat. Immunol. 11, 647-655 (2010).
    • (2010) Nat. Immunol , vol.11 , pp. 647-655
    • Pulendran, B.1    Tang, H.2    Manicassamy, S.3
  • 11
    • 0037080199 scopus 로고    scopus 로고
    • Cutting edge: Th2 response induction by dendritic cells: A role for CD40
    • MacDonald, A. S., Straw, A. D., Dalton, N. M. & Pearce, E. J. Cutting edge: Th2 response induction by dendritic cells: a role for CD40. J. Immunol. 168, 537-540 (2002).
    • (2002) J. Immunol , vol.168 , pp. 537-540
    • Macdonald, A.S.1    Straw, A.D.2    Dalton, N.M.3    Pearce, E.J.4
  • 12
    • 0034660408 scopus 로고    scopus 로고
    • A filarial nematode-secreted product signals dendritic cells to acquire a phenotype that drives development of Th2 cells
    • Whelan, M. et al. A filarial nematode-secreted product signals dendritic cells to acquire a phenotype that drives development of Th2 cells. J. Immunol. 164, 6453-6460 (2000).
    • (2000) J. Immunol , vol.164 , pp. 6453-6460
    • Whelan, M.1
  • 13
    • 0035808782 scopus 로고    scopus 로고
    • Development of allergic inflammation in a murine model of asthma is dependent on the costimulatory receptor OX40
    • Jember, A. G., Zuberi, R., Liu, F. T. & Croft, M. Development of allergic inflammation in a murine model of asthma is dependent on the costimulatory receptor OX40. J. Exp. Med. 193, 387-392 (2001).
    • (2001) J. Exp. Med , vol.193 , pp. 387-392
    • Jember, A.G.1    Zuberi, R.2    Liu, F.T.3    Croft, M.4
  • 14
    • 35748935554 scopus 로고    scopus 로고
    • Dendritic cell expression of OX40 ligand acts as a costimulatory, not polarizing, signal for optimal Th2 priming and memory induction in vivo
    • Jenkins, S. J., Perona-Wright, G., Worsley, A. G., Ishii, N. & MacDonald, A. S. Dendritic cell expression of OX40 ligand acts as a costimulatory, not polarizing, signal for optimal Th2 priming and memory induction in vivo. J. Immunol. 179, 3515-3523 (2007).
    • (2007) J. Immunol , vol.179 , pp. 3515-3523
    • Jenkins, S.J.1    Perona-Wright, G.2    Worsley, A.G.3    Ishii, N.4    Macdonald, A.S.5
  • 15
    • 59849090484 scopus 로고    scopus 로고
    • CD11b+ myeloid cells are the key mediators of Th2 cell homing into the airway in allergic inflammation
    • Medoff, B. D. et al. CD11b+ myeloid cells are the key mediators of Th2 cell homing into the airway in allergic inflammation. J. Immunol. 182, 623-635 (2009).
    • (2009) J. Immunol , vol.182 , pp. 623-635
    • Medoff, B.D.1
  • 16
    • 84862540443 scopus 로고    scopus 로고
    • Alternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivo
    • Cook, P. C. et al. Alternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivo. Proc. Natl Acad. Sci. USA 109, 9977-9982 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 9977-9982
    • Cook, P.C.1
  • 17
    • 0242580118 scopus 로고    scopus 로고
    • Cutting edge: Different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos
    • Agrawal, S. et al. Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos. J. Immunol. 171, 4984-4989 (2003).
    • (2003) J. Immunol , vol.171 , pp. 4984-4989
    • Agrawal, S.1
  • 18
    • 21044435329 scopus 로고    scopus 로고
    • Dendritic cell-intrinsic expression of NF-kappa B1 is required to promote optimal Th2 cell differentiation
    • Artis, D. et al. Dendritic cell-intrinsic expression of NF-kappa B1 is required to promote optimal Th2 cell differentiation. J. Immunol. 174, 7154-7159 (2005).
    • (2005) J. Immunol , vol.174 , pp. 7154-7159
    • Artis, D.1
  • 19
    • 84885778452 scopus 로고    scopus 로고
    • Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells
    • Gao, Y. et al. Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells. Immunity 39, 722-732 (2013).
    • (2013) Immunity , vol.39 , pp. 722-732
    • Gao, Y.1
  • 20
    • 84890918547 scopus 로고    scopus 로고
    • Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation
    • Williams, J. W. et al. Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation. Nat. Commun. 4, 2990 (2013).
    • (2013) Nat. Commun , vol.4 , pp. 2990
    • Williams, J.W.1
  • 21
    • 84875421490 scopus 로고    scopus 로고
    • The transcription factor STAT5 is critical in dendritic cells for the development of TH2 but not TH1 responses
    • Bell, B. D. et al. The transcription factor STAT5 is critical in dendritic cells for the development of TH2 but not TH1 responses. Nat. Immunol. 14, 364-371 (2013).
    • (2013) Nat. Immunol , vol.14 , pp. 364-371
    • Bell, B.D.1
  • 22
    • 58849092225 scopus 로고    scopus 로고
    • Epigenetic control of T-helper-cell differentiation
    • Wilson, C. B., Rowell, E. & Sekimata, M. Epigenetic control of T-helper-cell differentiation. Nat. Rev. Immunol. 9, 91-105 (2009).
    • (2009) Nat. Rev. Immunol , vol.9 , pp. 91-105
    • Wilson, C.B.1    Rowell, E.2    Sekimata, M.3
  • 23
    • 84859401055 scopus 로고    scopus 로고
    • Transcriptional and epigenetic control of T helper cell specification: Molecular mechanisms underlying commitment and plasticity
    • Kanno, Y., Vahedi, G., Hirahara, K., Singleton, K. & O'Shea, J. J. Transcriptional and epigenetic control of T helper cell specification: molecular mechanisms underlying commitment and plasticity. Annu. Rev. Immunol. 30, 707-731 (2012).
    • (2012) Annu. Rev. Immunol , vol.30 , pp. 707-731
    • Kanno, Y.1    Vahedi, G.2    Hirahara, K.3    Singleton, K.4    O'Shea, J.J.5
  • 24
    • 84861722003 scopus 로고    scopus 로고
    • Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response
    • Fang, T. C. et al. Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response. J. Exp. Med. 209, 661-669 (2012).
    • (2012) J. Exp. Med , vol.209 , pp. 661-669
    • Fang, T.C.1
  • 26
    • 32344450824 scopus 로고    scopus 로고
    • Genomic DNA methylation: The mark and its mediators
    • Klose, R. J. & Bird, A. P. Genomic DNA methylation: the mark and its mediators. Trends Biochem. Sci. 31, 89-97 (2006).
    • (2006) Trends Biochem. Sci , vol.31 , pp. 89-97
    • Klose, R.J.1    Bird, A.P.2
  • 27
    • 84918591406 scopus 로고    scopus 로고
    • MBD2 and MBD3: Elusive functions and mechanisms
    • Menafra, R. & Stunnenberg, H. G. MBD2 and MBD3: elusive functions and mechanisms. Front. Genet. 5, 428 (2014).
    • (2014) Front. Genet , vol.5 , pp. 428
    • Menafra, R.1    Stunnenberg, H.G.2
  • 28
    • 67650725820 scopus 로고    scopus 로고
    • The biology of chromatin remodeling complexes
    • Clapier, C. R. & Cairns, B. R. The biology of chromatin remodeling complexes. Annu. Rev. Biochem. 78, 273-304 (2009).
    • (2009) Annu. Rev. Biochem , vol.78 , pp. 273-304
    • Clapier, C.R.1    Cairns, B.R.2
  • 29
    • 28844490115 scopus 로고    scopus 로고
    • Role of MBD2 in gene regulation and tumorigenesis
    • Berger, J. & Bird, A. Role of MBD2 in gene regulation and tumorigenesis. Biochem. Soc. Trans. 33, 1537-1540 (2005).
    • (2005) Biochem. Soc. Trans , vol.33 , pp. 1537-1540
    • Berger, J.1    Bird, A.2
  • 30
    • 0036345455 scopus 로고    scopus 로고
    • Gene silencing quantitatively controls the function of a developmental trans-activator
    • Hutchins, A. S. et al. Gene silencing quantitatively controls the function of a developmental trans-activator. Mol. Cell. 10, 81-91 (2002).
    • (2002) Mol. Cell , vol.10 , pp. 81-91
    • Hutchins, A.S.1
  • 31
    • 27144534809 scopus 로고    scopus 로고
    • Cutting edge: A critical role for gene silencing in preventing excessive type 1 immunity
    • Hutchins, A. S. et al. Cutting edge: a critical role for gene silencing in preventing excessive type 1 immunity. J. Immunol. 175, 5606-5610 (2005).
    • (2005) J. Immunol , vol.175 , pp. 5606-5610
    • Hutchins, A.S.1
  • 32
    • 33748502968 scopus 로고    scopus 로고
    • Impaired memory CD8 T cell development in the absence of methyl-CpG-binding domain protein 2
    • Kersh, E. N. Impaired memory CD8 T cell development in the absence of methyl-CpG-binding domain protein 2. J. Immunol. 177, 3821-3826 (2006).
    • (2006) J. Immunol , vol.177 , pp. 3821-3826
    • Kersh, E.N.1
  • 33
    • 84886875425 scopus 로고    scopus 로고
    • Mbd2 promotes foxp3 demethylation and T-regulatory-cell function
    • Wang, L. et al. Mbd2 promotes foxp3 demethylation and T-regulatory-cell function. Mol. Cell. Biol. 33, 4106-4115 (2013).
    • (2013) Mol. Cell. Biol , vol.33 , pp. 4106-4115
    • Wang, L.1
  • 34
    • 0035834410 scopus 로고    scopus 로고
    • Defective antigen processing in GILT-free mice
    • Maric, M. et al. Defective antigen processing in GILT-free mice. Science 294, 1361-1365 (2001).
    • (2001) Science , vol.294 , pp. 1361-1365
    • Maric, M.1
  • 35
    • 33646484782 scopus 로고    scopus 로고
    • Novel function of alternatively activated macrophages: Stabilin-1-mediated clearance of SPARC
    • Kzhyshkowska, J. et al. Novel function of alternatively activated macrophages: stabilin-1-mediated clearance of SPARC. J. Immunol. 176, 5825-5832 (2006).
    • (2006) J. Immunol , vol.176 , pp. 5825-5832
    • Kzhyshkowska, J.1
  • 36
    • 34848869064 scopus 로고    scopus 로고
    • Slc11a1, formerly Nramp1, is expressed in dendritic cells and influences major histocompatibility complex class II expression and antigen-presenting cell function
    • Stober, C. B., Brode, S., White, J. K., Popoff, J. F. & Blackwell, J. M. Slc11a1, formerly Nramp1, is expressed in dendritic cells and influences major histocompatibility complex class II expression and antigen-presenting cell function. Infect. Immun. 75, 5059-5067 (2007).
    • (2007) Infect. Immun , vol.75 , pp. 5059-5067
    • Stober, C.B.1    Brode, S.2    White, J.K.3    Popoff, J.F.4    Blackwell, J.M.5
  • 37
    • 79960667861 scopus 로고    scopus 로고
    • Deletion of the murine scavenger receptor CD68
    • Song, L., Lee, C. & Schindler, C. Deletion of the murine scavenger receptor CD68. J. Lipid Res. 52, 1542-1550 (2011).
    • (2011) J. Lipid Res , vol.52 , pp. 1542-1550
    • Song, L.1    Lee, C.2    Schindler, C.3
  • 38
    • 84870430539 scopus 로고    scopus 로고
    • The mannose receptor
    • Martinez-Pomares, L. The mannose receptor. J. Leukoc. Biol. 92, 1177-1186 (2012).
    • (2012) J. Leukoc. Biol , vol.92 , pp. 1177-1186
    • Martinez-Pomares, L.1
  • 39
    • 84863104164 scopus 로고    scopus 로고
    • Mannose 6-phosphate receptor and sortilin mediated endocytosis of alpha-galactosidase A in kidney endothelial cells
    • Prabakaran, T. et al. Mannose 6-phosphate receptor and sortilin mediated endocytosis of alpha-galactosidase A in kidney endothelial cells. PLoS One 7, e39975 (2012).
    • (2012) PLoS One , vol.7 , pp. e39975
    • Prabakaran, T.1
  • 40
    • 84876278080 scopus 로고    scopus 로고
    • Methylation-dependent and -independent genomic targeting principles of the MBD protein family
    • Baubec, T., Ivanek, R., Lienert, F. & Schubeler, D. Methylation-dependent and -independent genomic targeting principles of the MBD protein family. Cell 153, 480-492 (2013).
    • (2013) Cell , vol.153 , pp. 480-492
    • Baubec, T.1    Ivanek, R.2    Lienert, F.3    Schubeler, D.4
  • 41
    • 38949174996 scopus 로고    scopus 로고
    • Intercellular adhesion molecule-1-dependent stable interactions between T cells and dendritic cells determine CD8+ T cell memory
    • Scholer, A., Hugues, S., Boissonnas, A., Fetler, L. & Amigorena, S. Intercellular adhesion molecule-1-dependent stable interactions between T cells and dendritic cells determine CD8+ T cell memory. Immunity 28, 258-270 (2008).
    • (2008) Immunity , vol.28 , pp. 258-270
    • Scholer, A.1    Hugues, S.2    Boissonnas, A.3    Fetler, L.4    Amigorena, S.5
  • 42
    • 33845386378 scopus 로고    scopus 로고
    • Phagocytosis induces lysosome remodeling and regulated presentation of particulate antigens by activated dendritic cells
    • Nayak, J. V. et al. Phagocytosis induces lysosome remodeling and regulated presentation of particulate antigens by activated dendritic cells. J. Immunol. 177, 8493-8503 (2006).
    • (2006) J. Immunol , vol.177 , pp. 8493-8503
    • Nayak, J.V.1
  • 43
    • 84857497002 scopus 로고    scopus 로고
    • Concurrent bacterial stimulation alters the function of helminth-activated dendritic cells, resulting in IL-17 induction
    • Perona-Wright, G. et al. Concurrent bacterial stimulation alters the function of helminth-activated dendritic cells, resulting in IL-17 induction. J. Immunol. 188, 2350-2358 (2012).
    • (2012) J. Immunol , vol.188 , pp. 2350-2358
    • Perona-Wright, G.1
  • 44
    • 0036636093 scopus 로고    scopus 로고
    • The immunobiology of schistosomiasis
    • Pearce, E. J. & MacDonald, A. S. The immunobiology of schistosomiasis. Nat. Rev. Immunol. 2, 499-511 (2002).
    • (2002) Nat. Rev. Immunol , vol.2 , pp. 499-511
    • Pearce, E.J.1    Macdonald, A.S.2
  • 45
    • 84876055957 scopus 로고    scopus 로고
    • Induction and regulation of pathogenic Th17 cell responses in schistosomiasis
    • Larkin, B. M. et al. Induction and regulation of pathogenic Th17 cell responses in schistosomiasis. Semin. Immunopathol. 34, 873-888 (2012).
    • (2012) Semin. Immunopathol , vol.34 , pp. 873-888
    • Larkin, B.M.1
  • 46
    • 34447275920 scopus 로고    scopus 로고
    • Notch-RBP-J signaling controls the homeostasis of CD8- dendritic cells in the spleen
    • Caton, M. L., Smith-Raska, M. R. & Reizis, B. Notch-RBP-J signaling controls the homeostasis of CD8- dendritic cells in the spleen. J. Exp. Med. 204, 1653-1664 (2007).
    • (2007) J. Exp. Med , vol.204 , pp. 1653-1664
    • Caton, M.L.1    Smith-Raska, M.R.2    Reizis, B.3
  • 47
    • 26644448473 scopus 로고    scopus 로고
    • A two-step process for cytokine production revealed by IL-4 dual-reporter mice
    • Mohrs, K., Wakil, A. E., Killeen, N., Locksley, R. M. & Mohrs, M. A two-step process for cytokine production revealed by IL-4 dual-reporter mice. Immunity 23, 419-429 (2005).
    • (2005) Immunity , vol.23 , pp. 419-429
    • Mohrs, K.1    Wakil, A.E.2    Killeen, N.3    Locksley, R.M.4    Mohrs, M.5
  • 48
    • 77951817855 scopus 로고    scopus 로고
    • Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
    • Neill, D. R. et al. Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature 464, 1367-1370 (2010).
    • (2010) Nature , vol.464 , pp. 1367-1370
    • Neill, D.R.1
  • 49
    • 80051930931 scopus 로고    scopus 로고
    • Orchestrating house dust mite-associated allergy in the lung
    • Gregory, L. G. & Lloyd, C. M. Orchestrating house dust mite-associated allergy in the lung. Trends Immunol. 32, 402-411 (2011).
    • (2011) Trends Immunol , vol.32 , pp. 402-411
    • Gregory, L.G.1    Lloyd, C.M.2
  • 50
    • 84860691114 scopus 로고    scopus 로고
    • The airway epithelium in asthma
    • Lambrecht, B. N. & Hammad, H. The airway epithelium in asthma. Nat. Med. 18, 684-692 (2012).
    • (2012) Nat. Med , vol.18 , pp. 684-692
    • Lambrecht, B.N.1    Hammad, H.2
  • 51
    • 79952729913 scopus 로고    scopus 로고
    • Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes
    • Barrett, N. A. et al. Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes. J. Exp. Med. 208, 593-604 (2011).
    • (2011) J. Exp. Med , vol.208 , pp. 593-604
    • Barrett, N.A.1
  • 52
    • 84859404292 scopus 로고    scopus 로고
    • Lung dendritic cells in respiratory viral infection and asthma: From protection to immunopathology
    • Lambrecht, B. N. & Hammad, H. Lung dendritic cells in respiratory viral infection and asthma: from protection to immunopathology. Annu. Rev. Immunol. 30, 243-270 (2012).
    • (2012) Annu. Rev. Immunol , vol.30 , pp. 243-270
    • Lambrecht, B.N.1    Hammad, H.2
  • 53
    • 84876358263 scopus 로고    scopus 로고
    • Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences
    • Gunther, K. et al. Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences. Nucleic Acids Res. 41, 3010-3021 (2013).
    • (2013) Nucleic Acids Res , vol.41 , pp. 3010-3021
    • Gunther, K.1
  • 54
    • 0035882012 scopus 로고    scopus 로고
    • CD8- dendritic cell activation status plays an integral role in influencing Th2 response development
    • MacDonald, A. S., Straw, A. D., Bauman, B. & Pearce, E. J. CD8- dendritic cell activation status plays an integral role in influencing Th2 response development. J. Immunol. 167, 1982-1988 (2001).
    • (2001) J. Immunol , vol.167 , pp. 1982-1988
    • Macdonald, A.S.1    Straw, A.D.2    Bauman, B.3    Pearce, E.J.4
  • 55
    • 77956899738 scopus 로고    scopus 로고
    • Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model
    • Yoshizaki, A. et al. Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model. J. Immunol. 185, 2502-2515 (2010).
    • (2010) J. Immunol , vol.185 , pp. 2502-2515
    • Yoshizaki, A.1
  • 56
    • 34548507983 scopus 로고    scopus 로고
    • CD137 ligand prevents the development of T-helper type 2 cell-mediated allergic asthma by interferon-gamma-producing CD8+ T cells
    • Polte, T., Jagemann, A., Foell, J., Mittler, R. S. & Hansen, G. CD137 ligand prevents the development of T-helper type 2 cell-mediated allergic asthma by interferon-gamma-producing CD8+ T cells. Clin. Exp. Allergy 37, 1374-1385 (2007).
    • (2007) Clin. Exp. Allergy , vol.37 , pp. 1374-1385
    • Polte, T.1    Jagemann, A.2    Foell, J.3    Mittler, R.S.4    Hansen, G.5
  • 57
    • 84892815323 scopus 로고    scopus 로고
    • Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation
    • Vander Lugt, B. et al. Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation. Nat. Immunol. 15, 161-167 (2014).
    • (2014) Nat. Immunol , vol.15 , pp. 161-167
    • Vander Lugt, B.1
  • 58
    • 80053086471 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling 2 is a feedback inhibitor of TLR-induced activation in human monocyte-derived dendritic cells
    • Posselt, G., Schwarz, H., Duschl, A. & Horejs-Hoeck, J. Suppressor of cytokine signaling 2 is a feedback inhibitor of TLR-induced activation in human monocyte-derived dendritic cells. J. Immunol. 187, 2875-2884 (2011).
    • (2011) J. Immunol , vol.187 , pp. 2875-2884
    • Posselt, G.1    Schwarz, H.2    Duschl, A.3    Horejs-Hoeck, J.4
  • 59
    • 0035868824 scopus 로고    scopus 로고
    • Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development
    • Hendrich, B., Guy, J., Ramsahoye, B., Wilson, V. A. & Bird, A. Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development. Genes Dev. 15, 710-723 (2001).
    • (2001) Genes Dev , vol.15 , pp. 710-723
    • Hendrich, B.1    Guy, J.2    Ramsahoye, B.3    Wilson, V.A.4    Bird, A.5
  • 60
    • 70149098555 scopus 로고    scopus 로고
    • Nonredundant roles for B cell-derived IL-10 in immune counter-regulation
    • Madan, R. et al. Nonredundant roles for B cell-derived IL-10 in immune counter-regulation. J. Immunol. 183, 2312-2320 (2009).
    • (2009) J. Immunol , vol.183 , pp. 2312-2320
    • Madan, R.1
  • 61
    • 0035094767 scopus 로고    scopus 로고
    • A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
    • Guy, J., Hendrich, B., Holmes, M., Martin, J. E. & Bird, A. A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nat. Genet. 27, 322-326 (2001).
    • (2001) Nat. Genet , vol.27 , pp. 322-326
    • Guy, J.1    Hendrich, B.2    Holmes, M.3    Martin, J.E.4    Bird, A.5
  • 62
    • 84961289551 scopus 로고    scopus 로고
    • Orchestrating high-throughput genomic analysis with Bioconductor
    • Huber, W. et al. Orchestrating high-throughput genomic analysis with Bioconductor. Nat. Methods 12, 115-121 (2015).
    • (2015) Nat. Methods , vol.12 , pp. 115-121
    • Huber, W.1
  • 63
    • 77549088298 scopus 로고    scopus 로고
    • Microarray data quality control improves the detection of differentially expressed genes
    • Kauffmann, A. & Huber, W. Microarray data quality control improves the detection of differentially expressed genes. Genomics 95, 138-142 (2010).
    • (2010) Genomics , vol.95 , pp. 138-142
    • Kauffmann, A.1    Huber, W.2
  • 64
    • 46249088370 scopus 로고    scopus 로고
    • Lumi: A pipeline for processing Illumina microarray
    • Du, P., Kibbe, W. A. & Lin, S. M. lumi: a pipeline for processing Illumina microarray. Bioinformatics 24, 1547-1548 (2008).
    • (2008) Bioinformatics , vol.24 , pp. 1547-1548
    • Du, P.1    Kibbe, W.A.2    Lin, S.M.3
  • 65
    • 84874271270 scopus 로고    scopus 로고
    • NCBI GEO: Archive for functional genomics data sets-update
    • Barrett, T. et al. NCBI GEO: archive for functional genomics data sets-update. Nucleic Acids Res. 41, D991-D995 (2013).
    • (2013) Nucleic Acids Res , vol.41 , pp. D991-D995
    • Barrett, T.1
  • 66
    • 84990251443 scopus 로고    scopus 로고
    • A temporal threshold for formaldehyde crosslinking and fixation
    • Schmiedeberg, L., Skene, P., Deaton, A. & Bird, A. A temporal threshold for formaldehyde crosslinking and fixation. PLoS One 4, e4636 (2009).
    • (2009) PLoS One , vol.4 , pp. e4636
    • Schmiedeberg, L.1    Skene, P.2    Deaton, A.3    Bird, A.4
  • 67
    • 67649884743 scopus 로고    scopus 로고
    • Fast and accurate short read alignment with Burrows-Wheeler transform
    • Li, H. & Durbin, R. Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25, 1754-1760 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 1754-1760
    • Li, H.1    Durbin, R.2
  • 68
    • 79959872458 scopus 로고    scopus 로고
    • Cell type-specific DNA methylation at intragenic CpG islands in the immune system
    • Deaton, A. M. et al. Cell type-specific DNA methylation at intragenic CpG islands in the immune system. Genome Res. 21, 1074-1086 (2011).
    • (2011) Genome Res , vol.21 , pp. 1074-1086
    • Deaton, A.M.1
  • 69
    • 84860330197 scopus 로고    scopus 로고
    • Protein kinase D isoforms are dispensable for integrinmediated lymphocyte adhesion and homing to lymphoid tissues
    • Matthews, S. A. et al. Protein kinase D isoforms are dispensable for integrinmediated lymphocyte adhesion and homing to lymphoid tissues. Eur. J. Immunol. 42, 1316-1326 (2012).
    • (2012) Eur. J. Immunol , vol.42 , pp. 1316-1326
    • Matthews, S.A.1
  • 70
    • 64849093183 scopus 로고    scopus 로고
    • A pivotal role for CD40-mediated IL-6 production by dendritic cells during IL-17 induction in vivo
    • Perona-Wright, G. et al. A pivotal role for CD40-mediated IL-6 production by dendritic cells during IL-17 induction in vivo. J. Immunol. 182, 2808-2815 (2009).
    • (2009) J. Immunol , vol.182 , pp. 2808-2815
    • Perona-Wright, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.