Role of MBD2 in gene regulation and tumorigenesis

Biochemical Society Transactions

Volumn 33, Issue 6, 2005, Pages 1537-1540

  Berger, J ^a   Bird, A ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

DNA methylation; Epigenetic mechanism; Histone deacetylase; Methyl CpG binding domain protein; Transcriptional regulation; Tumorigenesis

Indexed keywords

APC PROTEIN; DINUCLEOTIDE; DNA METHYLTRANSFERASE 1; METHYL CPG BINDING PROTEIN 2;

ADENOMA; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CHROMATIN; COLORECTAL CANCER; CONFERENCE PAPER; CPG ISLAND; DNA METHYLATION; EPIGENETICS; GENE CONTROL; GENE DOSAGE; GENE LOCATION; GENE REPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; GENOME IMPRINTING; HUMAN; LIFESPAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEFICIENCY; PROTEIN FAMILY; PROTEIN FUNCTION; TUMOR SUPPRESSOR GENE; VALIDATION PROCESS; X CHROMOSOME;

ANIMALS; COLORECTAL NEOPLASMS; CPG ISLANDS; DNA METHYLATION; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HUMANS; TRANSCRIPTION, GENETIC;

ANIMALIA; MURINAE;

EID: 28844490115     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST20051537     Document Type: Conference Paper

References (36)

1. Naveh-Many, T. and Cedar, H. (1982) Mol. Cell. Biol. 2, 758-762
2. Ehrlich, M., Gama-Sosa, M.A., Huang, L.H., Midgett, R.M., Kuo, K.C., McCune, R.A. and Gehrke, C. (1982) Nucleic Acids Res. 10, 2709-2721
3. Antequera, F. and Bird, A. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 11995-11999
4. Bird, A. (2002) Genes Dev. 16, 6-21
5. Meehan, R.R., Lewis, J.D., McKay, S., Kleiner, E.L. and Bird, A.P. (1989) Cell (Cambridge, Mass.) 58, 499-507
6. Lewis, J.D., Meehan, R.R., Henzel, W.J., Maurer-Fogy, I., Jeppesen, P., Klein, F. and Bird, A. (1992) Cell (Cambridge, Mass.) 69, 905-914
7. Hendrich, B. and Bird, A. (1998) Mol. Cell. Biol. 18, 6538-6547
8. Nan, X., Ng, H.H., Johnson, C.A., Laherty, C.D., Turner, B.M., Eisenman, R.N. and Bird, A. (1998) Nature (London) 393, 386-389
9. Jones, P.L., Veenstra, G.J., Wade, P.A., Vermaak, D., Kass, S.U., Landsberger, N., Strouboulis, J. and Wolffe, A.P. (1998) Nat. Genet. 19, 187-191
10. Fuks, F., Hurd, P.J., Wolf, D., Nan, X., Bird, A.P. and Kouzarides, T. (2003) J. Biol. Chem. 278, 4035-4040
11. Lachner, M. and Jenuwein, T. (2002) Curr. Opin. Cell Biol. 14, 286-298
12. Sarraf, S.A. and Stancheva, I. (2004) Mol. Cell 15, 595-605
13. Jorgensen, H.F., Ben-Porath, I. and Bird, A.P. (2004) Mol. Cell. Biol. 24, 3387-3395
14. Wade, P.A., Gegonne, A., Jones, P.L., Ballestar, E., Aubry, F. and Wolffe, A.P. (1999) Nat. Genet. 23, 62-66
15. Zhang, Y., Ng, H.H., Erdjument-Bromage, H., Tempst, P., Bird, A. and Reinberg, D. (1999) Genes Dev. 13, 1924-1935
16. Hendrich, B., Guy, J., Ramsahoye, B., Wilson, V.A. and Bird, A. (2001) Genes Dev. 15, 710-723
17. Hendrich, B., Hardeland, U., Ng, H.H., Jiricny, J. and Bird, A. (1999) Nature (London) 401, 301-304
18. Bhattacharya, S.K., Ramchandani, S., Cervoni, N. and Szyf, M. (1999) Nature (London) 397, 579-583
19. Ng, H.H., Zhang, V., Hendrich, B., Johnson, C.A., Turner, B.M., Erdjument-Bromage, H., Tempst, P., Reinberg, D. and Bird, A. (1999) Nat. Genet. 23, 58-61
20. Boeke, J., Ammerpohl, O., Kegel, S., Moehren, U. and Renkawitz, R. (2000) J. Biol. Chem. 275, 34963-34967
21. Feng, Q. and Zhang, Y. (2001) Genes Dev. 15, 827-832
22. Hutchins, A.S., Mullen, A.C., Lee, H.W., Sykes, K.J., High, F.A., Hendrich, B.D., Bird, A.P. and Reiner, S.L. (2002) Mol. Cell 10, 81-91
23. Sekimata, M., Takahashi, A., Murakami-Sekimata, A. and Homma, Y. (2001) J. Biol. Chem. 276, 42632-42638
24. Sekimata, M. and Homma, Y. (2004) Nucleic Acids Res. 32, 590-597
25. Sato, M., Horio, Y., Sekido, Y., Minna, J.D., Shimokata, K. and Hasegawa, Y. (2002) Oncogene 21, 4822-4829
26. Magdinier, F. and Wolffe, A.P. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 4990-4995
27. Lin, X. and Nelson, W.G. (2003) Cancer Res. 63, 498-504
28. Sansom, O.J., Berger, J., Bishop, S.M., Hendrich, B., Bird, A. and Clarke, A.R. (2003) Nat. Genet. 34, 145-147
29. Su, L.X., Kinzler, K.W., Vogelstein, B., Preisinger, A.C., Moser, A.R., Luongo, C., Gould, K.A. and Dove, W.F. (1992) Science 256, 668-670
30. Laird, P.W., Jackson-Grusby, L., Fazeli, A., Dickinson, S.L., Jung, W.E., Li, E., Weinberg, RA and Jaenisch, R. (1995) Cell (Cambridge, Mass.) 81, 197-205
31. Eads, C.A., Nickel, A.E. and Laird, P.W. (2002) Cancer Res. 62, 1296-1299
32. Campbell, P.M., Bovenzi, V. and Szyf, M. (2004) Carcinogenesis 25, 499-507
33. Feinberg, A.P. and Vogelstein, B. (1983) Nature (London) 301, 89-92
34. Eden, A., Gaudet, F., Waghmare, A. and Jaenisch, R. (2003) Science 300, 455
35. Gaudet, F., Hodgson, J.G., Eden, A., Jackson-Grusby, L., Dausman, J., Gray, J.W., Leonhardt, H. and Jaenisch, R. (2003) Science 300, 489-492
36. Sansom, O.J., Bishop, S.M., Bird, A. and Clarke, A.R. (2005) Oncogene 24, 2430-2432