-
1
-
-
0036347603
-
Asthma: An epidemic of dysregulated immunity
-
Umetsu DT, McIntire JJ, Akbari O, Macaubas C, DeKruyff RH. Asthma: an epidemic of dysregulated immunity. Nat Immunol 2002 3 : 715 20.
-
(2002)
Nat Immunol
, vol.3
, pp. 715-20
-
-
Umetsu, D.T.1
McIntire, J.J.2
Akbari, O.3
MacAubas, C.4
Dekruyff, R.H.5
-
2
-
-
0038658898
-
Costimulation of T cells by OX40, 4-1BB, and CD27
-
Croft M. Costimulation of T cells by OX40, 4-1BB, and CD27. Cytokine Growth Factor Rev 2003 14 : 265 73.
-
(2003)
Cytokine Growth Factor Rev
, vol.14
, pp. 265-73
-
-
Croft, M.1
-
3
-
-
33749353731
-
Direct evidence for a critical role of CD30 in the development of allergic asthma
-
Polte T, Behrendt AK, Hansen G. Direct evidence for a critical role of CD30 in the development of allergic asthma. J Allergy Clin Immunol 2006 : 942 8.
-
(2006)
J Allergy Clin Immunol
, pp. 942-8
-
-
Polte, T.1
Behrendt, A.K.2
Hansen, G.3
-
4
-
-
0033018101
-
T cell co-stimulatory molecules other than CD28
-
Watts TH, DeBenedette MA. T cell co-stimulatory molecules other than CD28. Curr Opin Immunol 1999 11 : 286 93.
-
(1999)
Curr Opin Immunol
, vol.11
, pp. 286-93
-
-
Watts, T.H.1
Debenedette, M.A.2
-
6
-
-
0031114039
-
Role of IL-12 and 4-1BB ligand in cytokine production by CD28+ and CD28- T cells
-
Chu NR, DeBenedette MA, Stiernholm BJ, Barber BH, Watts TH. Role of IL-12 and 4-1BB ligand in cytokine production by CD28+ and CD28- T cells. J Immunol 1997 158 : 3081 9.
-
(1997)
J Immunol
, vol.158
, pp. 3081-9
-
-
Chu, N.R.1
Debenedette, M.A.2
Stiernholm, B.J.3
Barber, B.H.4
Watts, T.H.5
-
7
-
-
0032754036
-
Analysis of 4-1BB ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus
-
DeBenedette MA, Wen T, Bachmann MF et al. Analysis of 4-1BB ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus. J Immunol 1999 163 : 4833 41.
-
(1999)
J Immunol
, vol.163
, pp. 4833-41
-
-
Debenedette, M.A.1
Wen, T.2
Bachmann, M.F.3
-
8
-
-
0033982793
-
Co-stimulation of antigen-specific CD4 T cells by 4-1BB ligand
-
Gramaglia I, Cooper D, Miner KT, Kwon BS, Croft M. Co-stimulation of antigen-specific CD4 T cells by 4-1BB ligand. Eur J Immunol 2000 30 : 392 402.
-
(2000)
Eur J Immunol
, vol.30
, pp. 392-402
-
-
Gramaglia, I.1
Cooper, D.2
Miner, K.T.3
Kwon, B.S.4
Croft, M.5
-
9
-
-
0031569279
-
Signals through 4-1BB are costimulatory to previously activated splenic T cells and inhibit activation-induced cell death
-
Hurtado JC, Kim YJ, Kwon BS. Signals through 4-1BB are costimulatory to previously activated splenic T cells and inhibit activation-induced cell death. J Immunol 1997 158 : 2600 9.
-
(1997)
J Immunol
, vol.158
, pp. 2600-9
-
-
Hurtado, J.C.1
Kim, Y.J.2
Kwon, B.S.3
-
10
-
-
0037094139
-
4-1BB ligand-mediated costimulation of human T cells induces CD4 and CD8 T cell expansion, cytokine production, and the development of cytolytic effector function
-
Wen T, Bukczynski J, Watts TH. 4-1BB ligand-mediated costimulation of human T cells induces CD4 and CD8 T cell expansion, cytokine production, and the development of cytolytic effector function. J Immunol 2002 168 : 4897 906.
-
(2002)
J Immunol
, vol.168
, pp. 4897-906
-
-
Wen, T.1
Bukczynski, J.2
Watts, T.H.3
-
11
-
-
0032101119
-
CD28-independent, TRAF2-dependent costimulation of resting T cells by 4-1BB ligand
-
Saoulli K, Lee SY, Cannons JL et al. CD28-independent, TRAF2-dependent costimulation of resting T cells by 4-1BB ligand. J Exp Med 1998 187 : 1849 62.
-
(1998)
J Exp Med
, vol.187
, pp. 1849-62
-
-
Saoulli, K.1
Lee, S.Y.2
Cannons, J.L.3
-
12
-
-
0027285735
-
Inducible T cell antigen 4-1BB. Analysis of expression and function
-
Pollok KE, Kim YJ, Zhou Z et al. Inducible T cell antigen 4-1BB. Analysis of expression and function. J Immunol 1993 150 : 771 81.
-
(1993)
J Immunol
, vol.150
, pp. 771-81
-
-
Pollok, K.E.1
Kim, Y.J.2
Zhou, Z.3
-
13
-
-
0028955074
-
Role of 4-1BB ligand in costimulation of T lymphocyte growth and its upregulation on M12 B lymphomas by cAMP
-
DeBenedette MA, Chu NR, Pollok KE et al. Role of 4-1BB ligand in costimulation of T lymphocyte growth and its upregulation on M12 B lymphomas by cAMP. J Exp Med 1995 181 : 985 92.
-
(1995)
J Exp Med
, vol.181
, pp. 985-92
-
-
Debenedette, M.A.1
Chu, N.R.2
Pollok, K.E.3
-
14
-
-
0033571176
-
Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy
-
Mittler RS, Bailey TS, Klussman K, Trailsmith MD, Hoffmann MK. Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy. J Exp Med 1999 190 : 1535 40.
-
(1999)
J Exp Med
, vol.190
, pp. 1535-40
-
-
Mittler, R.S.1
Bailey, T.S.2
Klussman, K.3
Trailsmith, M.D.4
Hoffmann, M.K.5
-
15
-
-
0031007143
-
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors
-
Melero I, Shuford WW, Newby SA et al. Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors. Nat Med 1997 3 : 682 5.
-
(1997)
Nat Med
, vol.3
, pp. 682-5
-
-
Melero, I.1
Shuford, W.W.2
Newby, S.A.3
-
16
-
-
0036104604
-
Gene therapy for cancer using single-chain Fv fragments specific for 4-1BB
-
Ye Z, Hellstrom I, Hayden-Ledbetter M, Dahlin A, Ledbetter JA, Hellstrom KE. Gene therapy for cancer using single-chain Fv fragments specific for 4-1BB. Nat Med 2002 8 : 343 8.
-
(2002)
Nat Med
, vol.8
, pp. 343-8
-
-
Ye, Z.1
Hellstrom, I.2
Hayden-Ledbetter, M.3
Dahlin, A.4
Ledbetter, J.A.5
Hellstrom, K.E.6
-
17
-
-
0036075444
-
In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses
-
Halstead ES, Mueller YM, Altman JD, Katsikis PD. In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses. Nat Immunol 2002 3 : 536 41.
-
(2002)
Nat Immunol
, vol.3
, pp. 536-41
-
-
Halstead, E.S.1
Mueller, Y.M.2
Altman, J.D.3
Katsikis, P.D.4
-
18
-
-
0036913169
-
Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease
-
Sun Y, Chen HM, Subudhi SK et al. Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease. Nat Med 2002 8 : 1405 13.
-
(2002)
Nat Med
, vol.8
, pp. 1405-13
-
-
Sun, Y.1
Chen, H.M.2
Subudhi, S.K.3
-
19
-
-
0038312910
-
CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB × NZW F1 mice
-
Foell J, Strahotin S, O'Neil SP et al. CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB × NZW F1 mice. J Clin Invest 2003 111 : 1505 18.
-
(2003)
J Clin Invest
, vol.111
, pp. 1505-18
-
-
Foell, J.1
Strahotin, S.2
O'Neil, S.P.3
-
20
-
-
7044261952
-
4-1BB-mediated immunotherapy of rheumatoid arthritis
-
Seo SK, Choi JH, Kim YH et al. 4-1BB-mediated immunotherapy of rheumatoid arthritis. Nat Med 2004 10 : 1088 94.
-
(2004)
Nat Med
, vol.10
, pp. 1088-94
-
-
Seo, S.K.1
Choi, J.H.2
Kim, Y.H.3
-
21
-
-
4444340010
-
Engagement of the CD137 (4-1BB) costimulatory molecule inhibits and reverses the autoimmune process in collagen-induced arthritis and establishes lasting disease resistance
-
Foell JL, Diez-Mendiondo BI, Diez OH et al. Engagement of the CD137 (4-1BB) costimulatory molecule inhibits and reverses the autoimmune process in collagen-induced arthritis and establishes lasting disease resistance. Immunology 2004 113 : 89 98.
-
(2004)
Immunology
, vol.113
, pp. 89-98
-
-
Foell, J.L.1
Diez-Mendiondo, B.I.2
Diez, O.H.3
-
22
-
-
0030845586
-
4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses
-
Shuford WW, Klussman K, Tritchler DD et al. 4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses. J Exp Med 1997 186 : 47 55.
-
(1997)
J Exp Med
, vol.186
, pp. 47-55
-
-
Shuford, W.W.1
Klussman, K.2
Tritchler, D.D.3
-
23
-
-
33645498741
-
CD137-mediated immunotherapy for allergic asthma
-
Polte T, Foell J, Werner C et al. CD137-mediated immunotherapy for allergic asthma. J Clin Invest 2006 116 : 1025 36.
-
(2006)
J Clin Invest
, vol.116
, pp. 1025-36
-
-
Polte, T.1
Foell, J.2
Werner, C.3
-
24
-
-
16044363695
-
IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses
-
Magram J, Connaughton SE, Warrier RR et al. IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses. Immunity 1996 4 : 471 81.
-
(1996)
Immunity
, vol.4
, pp. 471-81
-
-
Magram, J.1
Connaughton, S.E.2
Warrier, R.R.3
-
25
-
-
0030889510
-
Analysis of 4-1BBL and laminin binding to murine 4-1BB, a member of the tumor necrosis factor receptor superfamily, and comparison with human 4-1BB
-
Loo DT, Chalupny NJ, Bajorath J, Shuford WW, Mittler RS, Aruffo A. Analysis of 4-1BBL and laminin binding to murine 4-1BB, a member of the tumor necrosis factor receptor superfamily, and comparison with human 4-1BB. J Biol Chem 1997 272 : 6448 56.
-
(1997)
J Biol Chem
, vol.272
, pp. 6448-56
-
-
Loo, D.T.1
Chalupny, N.J.2
Bajorath, J.3
Shuford, W.W.4
Mittler, R.S.5
Aruffo, A.6
-
26
-
-
0030784497
-
Interleukin-12 is indispensable for protective immunity against Leishmania major
-
Mattner F, Di Padova K, Alber G. Interleukin-12 is indispensable for protective immunity against Leishmania major. Infect Immun 1997 65 : 4378 83.
-
(1997)
Infect Immun
, vol.65
, pp. 4378-83
-
-
Mattner, F.1
Di Padova, K.2
Alber, G.3
-
27
-
-
0032945548
-
Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation
-
Hansen G, Berry G, DeKruyff RH, Umetsu DT. Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation. J Clin Invest 1999 103 : 175 83.
-
(1999)
J Clin Invest
, vol.103
, pp. 175-83
-
-
Hansen, G.1
Berry, G.2
Dekruyff, R.H.3
Umetsu, D.T.4
-
28
-
-
0033979544
-
Vaccination with heat-killed Listeria as adjuvant reverses established allergen-induced airway hyperreactivity and inflammation: Role of CD8+ T cells and IL-18
-
Hansen G, Yeung VP, Berry G, Umetsu DT, DeKruyff RH. Vaccination with heat-killed Listeria as adjuvant reverses established allergen-induced airway hyperreactivity and inflammation: role of CD8+ T cells and IL-18. J Immunol 2000 164 : 223 30.
-
(2000)
J Immunol
, vol.164
, pp. 223-30
-
-
Hansen, G.1
Yeung, V.P.2
Berry, G.3
Umetsu, D.T.4
Dekruyff, R.H.5
-
29
-
-
0037313578
-
Interleukin-12 and the regulation of innate resistance and adaptive immunity
-
Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol 2003 3 : 133 46.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 133-46
-
-
Trinchieri, G.1
-
31
-
-
0027365746
-
Molecular cloning of a ligand for the inducible T cell gene 4-1BB: A member of an emerging family of cytokines with homology to tumor necrosis factor
-
Goodwin RG, Din WS, Davis-Smith T et al. Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor. Eur J Immunol 1993 23 : 2631 41.
-
(1993)
Eur J Immunol
, vol.23
, pp. 2631-41
-
-
Goodwin, R.G.1
Din, W.S.2
Davis-Smith, T.3
-
32
-
-
20244386539
-
Molecular and biological characterization of human 4-1BB and its ligand
-
Alderson MR, Smith CA, Tough TW et al. Molecular and biological characterization of human 4-1BB and its ligand. Eur J Immunol 1994 24 : 2219 27.
-
(1994)
Eur J Immunol
, vol.24
, pp. 2219-27
-
-
Alderson, M.R.1
Smith, C.A.2
Tough, T.W.3
-
33
-
-
1942501658
-
Bystander suppression of allergic airway inflammation by lung resident memory CD8+ T cells
-
Marsland BJ, Harris NL, Camberis M, Kopf M, Hook SM, Le Gros G. Bystander suppression of allergic airway inflammation by lung resident memory CD8+ T cells. Proc Natl Acad Sci USA 2004 101 : 6116 21.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 6116-21
-
-
Marsland, B.J.1
Harris, N.L.2
Camberis, M.3
Kopf, M.4
Hook, S.M.5
Le Gros, G.6
-
34
-
-
1642432076
-
4-1BB-ligand is regulated on human dendritic cells and induces the production of IL-12
-
Laderach D, Wesa A, Galy A. 4-1BB-ligand is regulated on human dendritic cells and induces the production of IL-12. Cell Immunol 2003 226 : 37 44.
-
(2003)
Cell Immunol
, vol.226
, pp. 37-44
-
-
Laderach, D.1
Wesa, A.2
Galy, A.3
-
35
-
-
0030586669
-
Nebulized IFN-gamma inhibits the development of secondary allergic responses in mice
-
Lack G, Bradley KL, Hamelmann E et al. Nebulized IFN-gamma inhibits the development of secondary allergic responses in mice. J Immunol 1996 157 : 1432 9.
-
(1996)
J Immunol
, vol.157
, pp. 1432-9
-
-
Lack, G.1
Bradley, K.L.2
Hamelmann, E.3
-
36
-
-
0030587861
-
Mucosal IFN-gamma gene transfer inhibits pulmonary allergic responses in mice
-
Li XM, Chopra RK, Chou TY, Schofield BH, Wills-Karp M, Huang SK. Mucosal IFN-gamma gene transfer inhibits pulmonary allergic responses in mice. J Immunol 1996 157 : 3216 9.
-
(1996)
J Immunol
, vol.157
, pp. 3216-9
-
-
Li, X.M.1
Chopra, R.K.2
Chou, T.Y.3
Schofield, B.H.4
Wills-Karp, M.5
Huang, S.K.6
-
37
-
-
0033230302
-
T helper 1 cells and interferon gamma regulate allergic airway inflammation and mucus production
-
Cohn L, Homer RJ, Niu N, Bottomly K. T helper 1 cells and interferon gamma regulate allergic airway inflammation and mucus production. J Exp Med 1999 190 : 1309 18.
-
(1999)
J Exp Med
, vol.190
, pp. 1309-18
-
-
Cohn, L.1
Homer, R.J.2
Niu, N.3
Bottomly, K.4
-
38
-
-
0035159169
-
Allergen-specific Th1 cells counteract efferent Th2 cell-dependent bronchial hyperresponsiveness and eosinophilic inflammation partly via IFN-gamma
-
Huang TJ, MacAry PA, Eynott P et al. Allergen-specific Th1 cells counteract efferent Th2 cell-dependent bronchial hyperresponsiveness and eosinophilic inflammation partly via IFN-gamma. J Immunol 2001 166 : 207 17.
-
(2001)
J Immunol
, vol.166
, pp. 207-17
-
-
Huang, T.J.1
MacAry, P.A.2
Eynott, P.3
-
39
-
-
3442875521
-
IFN-gamma inhibits the proliferation of allergen-activated T lymphocytes from atopic, asthmatic patients by inducing Fas/FasL-mediated apoptosis
-
De Rose V, Cappello P, Sorbello V et al. IFN-gamma inhibits the proliferation of allergen-activated T lymphocytes from atopic, asthmatic patients by inducing Fas/FasL-mediated apoptosis. J Leukoc Biol 2004 76 : 423 32.
-
(2004)
J Leukoc Biol
, vol.76
, pp. 423-32
-
-
De Rose, V.1
Cappello, P.2
Sorbello, V.3
-
40
-
-
0037059509
-
Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet
-
Finotto S, Neurath MF, Glickman JN et al. Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet. Science 2002 295 : 336 8.
-
(2002)
Science
, vol.295
, pp. 336-8
-
-
Finotto, S.1
Neurath, M.F.2
Glickman, J.N.3
-
41
-
-
12744262855
-
Increased interleukin-4, interleukin-5, and interferon-gamma in airway CD4+ and CD8+ T cells in atopic asthma
-
Cho SH, Stanciu LA, Holgate ST, Johnston SL. Increased interleukin-4, interleukin-5, and interferon-gamma in airway CD4+ and CD8+ T cells in atopic asthma. Am J Respir Crit Care Med 2005 171 : 224 30.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 224-30
-
-
Cho, S.H.1
Stanciu, L.A.2
Holgate, S.T.3
Johnston, S.L.4
-
42
-
-
33746847023
-
Role of local pulmonary IFN-gamma expression in murine allergic airway inflammation
-
Koch M, Witzenrath M, Reuter C et al. Role of local pulmonary IFN-gamma expression in murine allergic airway inflammation. Am J Respir Cell Mol Biol 2006 35 : 211 9.
-
(2006)
Am J Respir Cell Mol Biol
, vol.35
, pp. 211-9
-
-
Koch, M.1
Witzenrath, M.2
Reuter, C.3
|