-
1
-
-
33747474408
-
Non-alcoholic steatohepatitis and metabolic syndrome
-
Machado, M., Cortez-Pinto, H., Non-alcoholic steatohepatitis and metabolic syndrome. Curr. Opin. Clin. Nutr. Metab. Care. 2006, 9, 637-642.
-
(2006)
Curr. Opin. Clin. Nutr. Metab. Care.
, vol.9
, pp. 637-642
-
-
Machado, M.1
Cortez-Pinto, H.2
-
2
-
-
77649337140
-
Nonalcoholic fatty liver disease: pathology and pathogenesis
-
Tiniakos, D. G., Vos, M. B., Brunt, E. M., Nonalcoholic fatty liver disease: pathology and pathogenesis. Annu. Rev. Pathol. 2010, 5, 145-171.
-
(2010)
Annu. Rev. Pathol.
, vol.5
, pp. 145-171
-
-
Tiniakos, D.G.1
Vos, M.B.2
Brunt, E.M.3
-
3
-
-
84898439031
-
Nonalcoholic fatty liver disease: molecular mechanisms for the hepatic steatosis
-
Koo, S. H., Nonalcoholic fatty liver disease: molecular mechanisms for the hepatic steatosis. Clin. Mol. Hepatol. 2013, 19, 210-215.
-
(2013)
Clin. Mol. Hepatol.
, vol.19
, pp. 210-215
-
-
Koo, S.H.1
-
4
-
-
77950863893
-
Nontriglyceride hepatic lipotoxicity: the new paradigm for the pathogenesis of NASH
-
Neuschwander-Tetri, B. A., Nontriglyceride hepatic lipotoxicity: the new paradigm for the pathogenesis of NASH. Curr. Gastroenterol. Rep. 2010, 12, 49-56.
-
(2010)
Curr. Gastroenterol. Rep.
, vol.12
, pp. 49-56
-
-
Neuschwander-Tetri, B.A.1
-
5
-
-
80052596785
-
Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C
-
Miquilena-Colina, M. E., Lima-Cabello, E., Sánchez-Campos, S., García-Mediavilla, M. V. et al., Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C. Gut 2011, 60, 1394-1402.
-
(2011)
Gut
, vol.60
, pp. 1394-1402
-
-
Miquilena-Colina, M.E.1
Lima-Cabello, E.2
Sánchez-Campos, S.3
García-Mediavilla, M.V.4
-
6
-
-
84873700660
-
The human liver fatty acid binding protein (FABP1) gene is activated by FOXA1 and PPARalpha, and repressed by C/EBPalpha: implications in FABP1 down-regulation in nonalcoholic fatty liver disease
-
Guzmán, C., Benet, M., Pisonero-Vaquero, S., Moya, M. et al., The human liver fatty acid binding protein (FABP1) gene is activated by FOXA1 and PPARalpha and repressed by C/EBPalpha: implications in FABP1 down-regulation in nonalcoholic fatty liver disease. Biochim. Biophys. Acta 2013, 1831, 803-818.
-
(2013)
Biochim. Biophys. Acta
, vol.1831
, pp. 803-818
-
-
Guzmán, C.1
Benet, M.2
Pisonero-Vaquero, S.3
Moya, M.4
-
7
-
-
42949154244
-
Diagnosis and therapy of nonalcoholic steatohepatitis
-
Torres, D. M., Harrison, S. A., Diagnosis and therapy of nonalcoholic steatohepatitis. Gastroenterology 2008, 134, 1682-1698.
-
(2008)
Gastroenterology
, vol.134
, pp. 1682-1698
-
-
Torres, D.M.1
Harrison, S.A.2
-
8
-
-
84877269694
-
The effects of curcumin derivative on experimental steatohepatitis
-
Zeng, C. H., Zeng, P., Deng, Y. H., Shen, N. et al., The effects of curcumin derivative on experimental steatohepatitis. Zhonghua Gan Zang Bing Za Zhi 2011, 19, 454-459.
-
(2011)
Zhonghua Gan Zang Bing Za Zhi
, vol.19
, pp. 454-459
-
-
Zeng, C.H.1
Zeng, P.2
Deng, Y.H.3
Shen, N.4
-
9
-
-
84861603829
-
Silibinin modulates lipid homeostasis and inhibits nuclear factor kappa B activation in experimental nonalcoholic steatohepatitis
-
Salamone, F., Galvano, F., Cappello, F., Mangiameli, A. et al., Silibinin modulates lipid homeostasis and inhibits nuclear factor kappa B activation in experimental nonalcoholic steatohepatitis. Transl. Res. 2012, 159, 477-486.
-
(2012)
Transl. Res.
, vol.159
, pp. 477-486
-
-
Salamone, F.1
Galvano, F.2
Cappello, F.3
Mangiameli, A.4
-
10
-
-
78049438719
-
Fruit polyphenols, immunity and inflammation
-
González-Gallego, J., García-Mediavilla, M. V., Sánchez-Campos, S., Tuñón, M. J., Fruit polyphenols, immunity and inflammation. Br. J. Nutr. 2010, 104(Suppl 3), S15-S27.
-
(2010)
Br. J. Nutr.
, vol.104
, pp. S15-S27
-
-
González-Gallego, J.1
García-Mediavilla, M.V.2
Sánchez-Campos, S.3
Tuñón, M.J.4
-
11
-
-
84869869189
-
Dietary quercetin ameliorates nonalcoholic steatohepatitis induced by a high-fat diet in gerbils
-
Ying, H. Z., Liu, Y. H., Yu, B., Wang, Z. Y. et al., Dietary quercetin ameliorates nonalcoholic steatohepatitis induced by a high-fat diet in gerbils. Food Chem. Toxicol. 2013, 52, 53-60.
-
(2013)
Food Chem. Toxicol.
, vol.52
, pp. 53-60
-
-
Ying, H.Z.1
Liu, Y.H.2
Yu, B.3
Wang, Z.Y.4
-
12
-
-
84896896377
-
Modulation of PI3K-LXRalpha-dependent lipogenesis mediated by oxidative/nitrosative stress contributes to inhibition of HCV replication by quercetin
-
Pisonero-Vaquero, S., García-Mediavilla, M. V., Jorquera, F., Majano, P. L. et al., Modulation of PI3K-LXRalpha-dependent lipogenesis mediated by oxidative/nitrosative stress contributes to inhibition of HCV replication by quercetin. Lab. Invest. 2014, 94, 262-274.
-
(2014)
Lab. Invest.
, vol.94
, pp. 262-274
-
-
Pisonero-Vaquero, S.1
García-Mediavilla, M.V.2
Jorquera, F.3
Majano, P.L.4
-
13
-
-
84904618577
-
Quercetin improves insulin resistance and hepatic lipid accumulation in a NAFLD cell model
-
Li, X., Wang, R., Zhou, N., Wang, X. et al., Quercetin improves insulin resistance and hepatic lipid accumulation in a NAFLD cell model. Biomed. Rep. 2013, 1, 71-76.
-
(2013)
Biomed. Rep.
, vol.1
, pp. 71-76
-
-
Li, X.1
Wang, R.2
Zhou, N.3
Wang, X.4
-
14
-
-
84873696060
-
Quercetin ameliorate insulin resistance and up-regulates cellular antioxidants during oleic acid induced hepatic steatosis in HepG2 cells
-
Vidyashankar, S., Sandeep Varma, R., Patki, P. S., Quercetin ameliorate insulin resistance and up-regulates cellular antioxidants during oleic acid induced hepatic steatosis in HepG2 cells. Toxicol. In Vitro. 2013, 27, 945-953.
-
(2013)
Toxicol. In Vitro.
, vol.27
, pp. 945-953
-
-
Vidyashankar, S.1
Sandeep Varma, R.2
Patki, P.S.3
-
15
-
-
20044374023
-
Design and validation of a histological scoring system for nonalcoholic fatty liver disease
-
Kleiner, D. E., Brunt, E. M., VanNatta, M., Behling, C. et al., Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005, 41, 1313-1321.
-
(2005)
Hepatology
, vol.41
, pp. 1313-1321
-
-
Kleiner, D.E.1
Brunt, E.M.2
Van Natta, M.3
Behling, C.4
-
16
-
-
77951436599
-
Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway
-
Gupta, N. A., Mells, J., Dunham, R. M., Grakoui, A. et al., Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway. Hepatology 2010, 51, 1584-1592.
-
(2010)
Hepatology
, vol.51
, pp. 1584-1592
-
-
Gupta, N.A.1
Mells, J.2
Dunham, R.M.3
Grakoui, A.4
-
17
-
-
33745802227
-
Roles of phosphatidylinositol 3-kinase and osteopontin in steatosis and aminotransferase release by hepatocytes treated with methionine-choline-deficient medium
-
Sahai, A., Pan, X., Paul, R., Malladi, P. et al., Roles of phosphatidylinositol 3-kinase and osteopontin in steatosis and aminotransferase release by hepatocytes treated with methionine-choline-deficient medium. Am. J. Physiol. Gastrointest. Liver Physiol. 2006, 291, G55-G62.
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.291
, pp. G55-G62
-
-
Sahai, A.1
Pan, X.2
Paul, R.3
Malladi, P.4
-
18
-
-
53649084494
-
A comparison of the effects of kaempferol and quercetin on cytokine-induced pro-inflammatory status of cultured human endothelial cells
-
Crespo, I., García-Mediavilla, M. V., Gutiérrez, B., Sánchez-Campos, S. et al., A comparison of the effects of kaempferol and quercetin on cytokine-induced pro-inflammatory status of cultured human endothelial cells. Br. J. Nutr. 2008, 100, 968-976.
-
(2008)
Br. J. Nutr.
, vol.100
, pp. 968-976
-
-
Crespo, I.1
García-Mediavilla, M.V.2
Gutiérrez, B.3
Sánchez-Campos, S.4
-
19
-
-
64549142339
-
Hepatitis C virus NS5A and core proteins induce oxidative stress-mediated calcium signalling alterations in hepatocytes
-
Dionisio, N., García-Mediavilla, M. V., Sánchez-Campos, S., Majano, P. L. et al., Hepatitis C virus NS5A and core proteins induce oxidative stress-mediated calcium signalling alterations in hepatocytes. J. Hepatol. 2009, 50, 872-882.
-
(2009)
J. Hepatol.
, vol.50
, pp. 872-882
-
-
Dionisio, N.1
García-Mediavilla, M.V.2
Sánchez-Campos, S.3
Majano, P.L.4
-
20
-
-
59249095410
-
Effects of glutamine on proinflammatory gene expression and activation of nuclear factor kappa B and signal transducers and activators of transcription in TNBS-induced colitis
-
Kretzmann, N. A., Fillmann, H., Mauriz, J. L., Marroni, C. A. et al., Effects of glutamine on proinflammatory gene expression and activation of nuclear factor kappa B and signal transducers and activators of transcription in TNBS-induced colitis. Inflamm. Bowel Dis. 2008, 14, 1504-1513.
-
(2008)
Inflamm. Bowel Dis.
, vol.14
, pp. 1504-1513
-
-
Kretzmann, N.A.1
Fillmann, H.2
Mauriz, J.L.3
Marroni, C.A.4
-
21
-
-
0034092716
-
CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis
-
Leclercq, I. A., Farrell, G. C., Field, J., Bell, D. R. et al., CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis. J. Clin. Invest. 2000, 105, 1067-1075.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1067-1075
-
-
Leclercq, I.A.1
Farrell, G.C.2
Field, J.3
Bell, D.R.4
-
22
-
-
0038643427
-
Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice
-
Ip, E., Farrell, G. C., Robertson, G., Hall, P. et al., Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice. Hepatology 2003, 38, 123-132.
-
(2003)
Hepatology
, vol.38
, pp. 123-132
-
-
Ip, E.1
Farrell, G.C.2
Robertson, G.3
Hall, P.4
-
23
-
-
84928209634
-
Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up
-
Ekstedt, M., Hagstrom, H., Nasr, P., Fredrikson, M. et al., Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up. Hepatology 2014, doi:10.1002/hep.27368.
-
(2014)
Hepatology
-
-
Ekstedt, M.1
Hagstrom, H.2
Nasr, P.3
Fredrikson, M.4
-
24
-
-
77954239704
-
A meta-analysis of randomized trials for the treatment of nonalcoholic fatty liver disease
-
Musso, G., Gambino, R., Cassader, M., Pagano, G., A meta-analysis of randomized trials for the treatment of nonalcoholic fatty liver disease. Hepatology 2010, 52, 79-104.
-
(2010)
Hepatology
, vol.52
, pp. 79-104
-
-
Musso, G.1
Gambino, R.2
Cassader, M.3
Pagano, G.4
-
25
-
-
84858126932
-
Non-alcoholic steatohepatitis: what can we learn from animal models?
-
Almonacid-Urrego, C. C., Sánchez-Campos, S., Tuñón, M. J., González-Gallego, J., Non-alcoholic steatohepatitis: what can we learn from animal models?. Curr. Med. Chem. 2012, 19, 1389-1404.
-
(2012)
Curr. Med. Chem.
, vol.19
, pp. 1389-1404
-
-
Almonacid-Urrego, C.C.1
Sánchez-Campos, S.2
Tuñón, M.J.3
González-Gallego, J.4
-
26
-
-
84861738395
-
Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
-
Takahashi, Y., Soejima, Y., Fukusato, T., Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. World J. Gastroenterol. 2012, 18, 2300-2308.
-
(2012)
World J. Gastroenterol.
, vol.18
, pp. 2300-2308
-
-
Takahashi, Y.1
Soejima, Y.2
Fukusato, T.3
-
27
-
-
84873257485
-
Dietary fat source alters hepatic gene expression profile and determines the type of liver pathology in rats overfed via total enteral nutrition
-
Ronis, M. J., Baumgardner, J. N., Marecki, J. C., Hennings, L. et al., Dietary fat source alters hepatic gene expression profile and determines the type of liver pathology in rats overfed via total enteral nutrition. Physiol. Genomics 2012, 44, 1073-1089.
-
(2012)
Physiol. Genomics
, vol.44
, pp. 1073-1089
-
-
Ronis, M.J.1
Baumgardner, J.N.2
Marecki, J.C.3
Hennings, L.4
-
28
-
-
84872089657
-
Quercetin reduces high-fat diet-induced fat accumulation in the liver by regulating lipid metabolism genes
-
Jung, C. H., Cho, I., Ahn, J., Jeon, T. I. et al., Quercetin reduces high-fat diet-induced fat accumulation in the liver by regulating lipid metabolism genes. Phytother. Res. 2013, 27, 139-143.
-
(2013)
Phytother. Res.
, vol.27
, pp. 139-143
-
-
Jung, C.H.1
Cho, I.2
Ahn, J.3
Jeon, T.I.4
-
29
-
-
84910095428
-
Extracts from Salvia-Nelumbinis naturalis alleviate hepatosteatosis via improving hepatic insulin sensitivity
-
Zhang, L., Xu, J., Song, H., Yao, Z. et al., Extracts from Salvia-Nelumbinis naturalis alleviate hepatosteatosis via improving hepatic insulin sensitivity. J. Transl. Med. 2014, 12, 236-014-0236-8.
-
(2014)
J. Transl. Med.
, vol.12
, pp. 236
-
-
Zhang, L.1
Xu, J.2
Song, H.3
Yao, Z.4
-
30
-
-
79251639639
-
Enhanced expression of pro-inflammatory mediators and liver X-receptor-regulated lipogenic genes in non-alcoholic fatty liver disease and hepatitis C
-
Lima-Cabello, E., García-Mediavilla, M. V., Miquilena-Colina, M. E., Vargas-Castrillón, J. et al., Enhanced expression of pro-inflammatory mediators and liver X-receptor-regulated lipogenic genes in non-alcoholic fatty liver disease and hepatitis C. Clin. Sci. 2011, 120, 239-250.
-
(2011)
Clin. Sci.
, vol.120
, pp. 239-250
-
-
Lima-Cabello, E.1
García-Mediavilla, M.V.2
Miquilena-Colina, M.E.3
Vargas-Castrillón, J.4
-
31
-
-
84869121923
-
Quercetin treatment ameliorates inflammation and fibrosis in mice with nonalcoholic steatohepatitis
-
Marcolin, E., San-Miguel, B., Vallejo, D., Tieppo, J. et al., Quercetin treatment ameliorates inflammation and fibrosis in mice with nonalcoholic steatohepatitis. J. Nutr. 2012, 142, 1821-1828.
-
(2012)
J. Nutr.
, vol.142
, pp. 1821-1828
-
-
Marcolin, E.1
San-Miguel, B.2
Vallejo, D.3
Tieppo, J.4
-
32
-
-
84863550183
-
Quercetin ameliorates cardiovascular, hepatic, and metabolic changes in diet-induced metabolic syndrome in rats
-
Panchal, S. K., Poudyal, H., Brown, L., Quercetin ameliorates cardiovascular, hepatic, and metabolic changes in diet-induced metabolic syndrome in rats. J. Nutr. 2012, 142, 1026-1032.
-
(2012)
J. Nutr.
, vol.142
, pp. 1026-1032
-
-
Panchal, S.K.1
Poudyal, H.2
Brown, L.3
-
33
-
-
40849085134
-
Differential effects of dietary flavonoids on reactive oxygen and nitrogen species generation and changes in antioxidant enzyme expression induced by proinflammatory cytokines in Chang Liver cells
-
Crespo, I., García-Mediavilla, M. V., Almar, M., González, P. et al., Differential effects of dietary flavonoids on reactive oxygen and nitrogen species generation and changes in antioxidant enzyme expression induced by proinflammatory cytokines in Chang Liver cells. Food Chem. Toxicol. 2008, 46, 1555-1569.
-
(2008)
Food Chem. Toxicol.
, vol.46
, pp. 1555-1569
-
-
Crespo, I.1
García-Mediavilla, M.V.2
Almar, M.3
González, P.4
-
34
-
-
84902551389
-
De novo lipogenesis in health and disease
-
Ameer, F., Scandiuzzi, L., Hasnain, S., Kalbacher, H., Zaidi, N., De novo lipogenesis in health and disease. Metabolism 2014, 63, 895-902.
-
(2014)
Metabolism
, vol.63
, pp. 895-902
-
-
Ameer, F.1
Scandiuzzi, L.2
Hasnain, S.3
Kalbacher, H.4
Zaidi, N.5
-
35
-
-
70349260288
-
Fenofibrate differentially regulates plasminogen activator inhibitor-1 gene expression via adenosine monophosphate-activated protein kinase-dependent induction of orphan nuclear receptor small heterodimer partner
-
Chanda, D., Lee, C. H., Kim, Y. H., Noh, J. R. et al., Fenofibrate differentially regulates plasminogen activator inhibitor-1 gene expression via adenosine monophosphate-activated protein kinase-dependent induction of orphan nuclear receptor small heterodimer partner. Hepatology 2009, 50, 880-892.
-
(2009)
Hepatology
, vol.50
, pp. 880-892
-
-
Chanda, D.1
Lee, C.H.2
Kim, Y.H.3
Noh, J.R.4
-
36
-
-
84859935042
-
Time-dependent changes in lipid metabolism in mice with methionine choline deficiency-induced fatty liver disease
-
Park, H. S., Jeon, B. H., Woo, S. H., Leem, J. et al., Time-dependent changes in lipid metabolism in mice with methionine choline deficiency-induced fatty liver disease. Mol. Cells 2011, 32, 571-577.
-
(2011)
Mol. Cells
, vol.32
, pp. 571-577
-
-
Park, H.S.1
Jeon, B.H.2
Woo, S.H.3
Leem, J.4
-
37
-
-
84922696660
-
CXCL10 plays a key role as an inflammatory mediator and a non-invasive biomarker of non-alcoholic steatohepatitis
-
Zhang, X., Shen, J., Man, K., Chu, E. S. et al., CXCL10 plays a key role as an inflammatory mediator and a non-invasive biomarker of non-alcoholic steatohepatitis. J. Hepatol. 2014, 61, 1365-1375.
-
(2014)
J. Hepatol.
, vol.61
, pp. 1365-1375
-
-
Zhang, X.1
Shen, J.2
Man, K.3
Chu, E.S.4
-
38
-
-
84879357128
-
Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats
-
Wang, W., Wang, C., Ding, X. Q., Pan, Y. et al., Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats. Br. J. Pharmacol. 2013, 169, 1352-1371.
-
(2013)
Br. J. Pharmacol.
, vol.169
, pp. 1352-1371
-
-
Wang, W.1
Wang, C.2
Ding, X.Q.3
Pan, Y.4
-
39
-
-
63749108094
-
Cellular fatty acid uptake: a pathway under construction
-
Su, X., Abumrad, N. A., Cellular fatty acid uptake: a pathway under construction. Trends Endocrinol. Metab. 2009, 20, 72-77.
-
(2009)
Trends Endocrinol. Metab.
, vol.20
, pp. 72-77
-
-
Su, X.1
Abumrad, N.A.2
-
40
-
-
33947140482
-
Importance of the carboxyl terminus of FAT/CD36 for plasma membrane localization and function in long-chain fatty acid uptake
-
Eyre, N. S., Cleland, L. G., Tandon, N. N., Mayrhofer, G., Importance of the carboxyl terminus of FAT/CD36 for plasma membrane localization and function in long-chain fatty acid uptake. J. Lipid Res. 2007, 48, 528-542.
-
(2007)
J. Lipid Res.
, vol.48
, pp. 528-542
-
-
Eyre, N.S.1
Cleland, L.G.2
Tandon, N.N.3
Mayrhofer, G.4
-
41
-
-
84904678224
-
Inflammatory stress increases hepatic CD36 translational efficiency via activation of the mTOR signalling pathway
-
Wang, C., Hu, L., Zhao, L., Yang, P. et al., Inflammatory stress increases hepatic CD36 translational efficiency via activation of the mTOR signalling pathway. PLoS One 2014, 9, e103071.
-
(2014)
PLoS One
, vol.9
, pp. e103071
-
-
Wang, C.1
Hu, L.2
Zhao, L.3
Yang, P.4
-
42
-
-
84897589965
-
Effects of treatment with hydrogen sulfide on methionine-choline deficient diet-induced non-alcoholic steatohepatitis in rats
-
Luo, Z. L., Tang, L. J., Wang, T., Dai, R. W. et al., Effects of treatment with hydrogen sulfide on methionine-choline deficient diet-induced non-alcoholic steatohepatitis in rats. J. Gastroenterol. Hepatol. 2014, 29, 215-222.
-
(2014)
J. Gastroenterol. Hepatol.
, vol.29
, pp. 215-222
-
-
Luo, Z.L.1
Tang, L.J.2
Wang, T.3
Dai, R.W.4
-
43
-
-
63649104470
-
Analysis of hepatic genes involved in the metabolism of fatty acids and iron in nonalcoholic fatty liver disease
-
Mitsuyoshi, H., Yasui, K., Harano, Y., Endo, M. et al., Analysis of hepatic genes involved in the metabolism of fatty acids and iron in nonalcoholic fatty liver disease. Hepatol. Res. 2009, 39, 366-373.
-
(2009)
Hepatol. Res.
, vol.39
, pp. 366-373
-
-
Mitsuyoshi, H.1
Yasui, K.2
Harano, Y.3
Endo, M.4
-
44
-
-
52049117445
-
Silencing of hepatic fatty acid transporter protein 5 in vivo reverses diet-induced non-alcoholic fatty liver disease and improves hyperglycemia
-
Doege, H., Grimm, D., Falcon, A., Tsang, B. et al., Silencing of hepatic fatty acid transporter protein 5 in vivo reverses diet-induced non-alcoholic fatty liver disease and improves hyperglycemia. J. Biol. Chem. 2008, 283, 22186-22192.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 22186-22192
-
-
Doege, H.1
Grimm, D.2
Falcon, A.3
Tsang, B.4
-
45
-
-
84899999241
-
Lipid modulatory activities of Cichorium glandulosum Boiss et Huet are mediated by multiple components within hepatocytes
-
Ding, L., Liu, J. L., Hassan, W., Wang, L. L. et al., Lipid modulatory activities of Cichorium glandulosum Boiss et Huet are mediated by multiple components within hepatocytes. Sci. Rep. 2014, 4, 4715.
-
(2014)
Sci. Rep.
, vol.4
, pp. 4715
-
-
Ding, L.1
Liu, J.L.2
Hassan, W.3
Wang, L.L.4
-
46
-
-
39549108872
-
Phyllanthus urinaria ameliorates the severity of nutritional steatohepatitis both in vitro and in vivo
-
Shen, B., Yu, J., Wang, S., Chu, E. S. et al., Phyllanthus urinaria ameliorates the severity of nutritional steatohepatitis both in vitro and in vivo. Hepatology 2008, 47, 473-483.
-
(2008)
Hepatology
, vol.47
, pp. 473-483
-
-
Shen, B.1
Yu, J.2
Wang, S.3
Chu, E.S.4
-
47
-
-
44049084267
-
Transcriptional regulation of fatty acid translocase/CD36 expression by CCAAT/enhancer-binding protein alpha
-
Qiao, L., Zou, C., Shao, P., Schaack, J. et al., Transcriptional regulation of fatty acid translocase/CD36 expression by CCAAT/enhancer-binding protein alpha. J. Biol. Chem. 2008, 283, 8788-8795.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 8788-8795
-
-
Qiao, L.1
Zou, C.2
Shao, P.3
Schaack, J.4
-
48
-
-
0037155907
-
Increased reactive oxygen species production down-regulates peroxisome proliferator-activated alpha pathway in C2C12 skeletal muscle cells
-
Cabrero, A., Alegret, M., Sanchez, R. M., Adzet, T. et al., Increased reactive oxygen species production down-regulates peroxisome proliferator-activated alpha pathway in C2C12 skeletal muscle cells. J. Biol. Chem. 2002, 277, 10100-10107.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 10100-10107
-
-
Cabrero, A.1
Alegret, M.2
Sanchez, R.M.3
Adzet, T.4
-
49
-
-
0032479423
-
Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue- and inducer-specific manner
-
Motojima, K., Passilly, P., Peters, J. M., Gonzalez, F. J. et al., Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue- and inducer-specific manner. J. Biol. Chem. 1998, 273, 16710-16714.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16710-16714
-
-
Motojima, K.1
Passilly, P.2
Peters, J.M.3
Gonzalez, F.J.4
-
50
-
-
34547411540
-
Molecular characterization of the role of orphan receptor small heterodimer partner in development of fatty liver
-
Huang, J., Iqbal, J., Saha, P. K., Liu, J. et al., Molecular characterization of the role of orphan receptor small heterodimer partner in development of fatty liver. Hepatology 2007, 46, 147-157.
-
(2007)
Hepatology
, vol.46
, pp. 147-157
-
-
Huang, J.1
Iqbal, J.2
Saha, P.K.3
Liu, J.4
-
51
-
-
84876146580
-
Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis
-
Bechmann, L. P., Kocabayoglu, P., Sowa, J. P., Sydor, S. et al., Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis. Hepatology 2013, 57, 1394-1406.
-
(2013)
Hepatology
, vol.57
, pp. 1394-1406
-
-
Bechmann, L.P.1
Kocabayoglu, P.2
Sowa, J.P.3
Sydor, S.4
-
52
-
-
84877956229
-
Small heterodimer partner-targeting therapy inhibits systemic inflammatory responses through mitochondrial uncoupling protein 2
-
Yang, C. S., Yuk, J. M., Kim, J. J., Hwang, J. H. et al., Small heterodimer partner-targeting therapy inhibits systemic inflammatory responses through mitochondrial uncoupling protein 2. PLoS One 2013, 8, e63435.
-
(2013)
PLoS One
, vol.8
, pp. e63435
-
-
Yang, C.S.1
Yuk, J.M.2
Kim, J.J.3
Hwang, J.H.4
-
53
-
-
34547476712
-
A little orphan runs to fat: the orphan receptor small heterodimer partner as a key player in the regulation of hepatic lipid metabolism
-
Trauner, M., A little orphan runs to fat: the orphan receptor small heterodimer partner as a key player in the regulation of hepatic lipid metabolism. Hepatology 2007, 46, 1-5.
-
(2007)
Hepatology
, vol.46
, pp. 1-5
-
-
Trauner, M.1
-
54
-
-
55449133428
-
Dietary procyanidins lower triglyceride levels signaling through the nuclear receptor small heterodimer partner
-
Del Bas, J. M., Ricketts, M. L., Baiges, I., Quesada, H. et al., Dietary procyanidins lower triglyceride levels signaling through the nuclear receptor small heterodimer partner. Mol. Nutr. Food Res. 2008, 52, 1172-1181.
-
(2008)
Mol. Nutr. Food Res.
, vol.52
, pp. 1172-1181
-
-
Del Bas, J.M.1
Ricketts, M.L.2
Baiges, I.3
Quesada, H.4
-
55
-
-
84864475305
-
Liver X receptor alpha-mediated regulation of lipogenesis by core and NS5A proteins contributes to HCV-induced liver steatosis and HCV replication
-
García-Mediavilla, M. V., Pisonero-Vaquero, S., Lima-Cabello, E., Benedicto, I. et al., Liver X receptor alpha-mediated regulation of lipogenesis by core and NS5A proteins contributes to HCV-induced liver steatosis and HCV replication. Lab. Invest. 2012, 92, 1191-1202.
-
(2012)
Lab. Invest.
, vol.92
, pp. 1191-1202
-
-
García-Mediavilla, M.V.1
Pisonero-Vaquero, S.2
Lima-Cabello, E.3
Benedicto, I.4
-
56
-
-
83355174170
-
Impaired activation of phosphatidylinositol 3-kinase by leptin is a novel mechanism of hepatic leptin resistance in NAFLD
-
Xu, D., Huang, X. D., Yuan, J. P., Wu, J. et al., Impaired activation of phosphatidylinositol 3-kinase by leptin is a novel mechanism of hepatic leptin resistance in NAFLD. Hepatogastroenterology 2011, 58, 1703-1707.
-
(2011)
Hepatogastroenterology
, vol.58
, pp. 1703-1707
-
-
Xu, D.1
Huang, X.D.2
Yuan, J.P.3
Wu, J.4
-
57
-
-
84872296508
-
27-hydroxycholesterol induces production of tumor necrosis factor-alpha from macrophages
-
Kim, S. M., Jang, H., Son, Y., Lee, S. A. et al., 27-hydroxycholesterol induces production of tumor necrosis factor-alpha from macrophages. Biochem. Biophys. Res. Commun. 2013, 430, 454-459.
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.430
, pp. 454-459
-
-
Kim, S.M.1
Jang, H.2
Son, Y.3
Lee, S.A.4
-
58
-
-
84860530517
-
Co-stimulation of PAFR and CD36 is required for oxLDL-induced human macrophages activation
-
Rios, F. J., Koga, M. M., Ferracini, M., Jancar, S., Co-stimulation of PAFR and CD36 is required for oxLDL-induced human macrophages activation. PLoS One 2012, 7, e36632.
-
(2012)
PLoS One
, vol.7
, pp. e36632
-
-
Rios, F.J.1
Koga, M.M.2
Ferracini, M.3
Jancar, S.4
-
59
-
-
34047263219
-
Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/enhancer binding protein alpha by phosphatidylinositol 3-kinase signaling cascade
-
Datta, J., Majumder, S., Kutay, H., Motiwala, T. et al., Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/enhancer binding protein alpha by phosphatidylinositol 3-kinase signaling cascade. Cancer Res. 2007, 67, 2736-2746.
-
(2007)
Cancer Res
, vol.67
, pp. 2736-2746
-
-
Datta, J.1
Majumder, S.2
Kutay, H.3
Motiwala, T.4
-
60
-
-
0036632368
-
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
-
Vivanco, I., Sawyers, C. L., The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat. Rev. Cancer 2002, 2, 489-501.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
61
-
-
1942466512
-
Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activity
-
Wang, G. L., Iakova, P., Wilde, M., Awad, S. et al., Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activity. Genes Dev. 2004, 18, 912-925.
-
(2004)
Genes Dev
, vol.18
, pp. 912-925
-
-
Wang, G.L.1
Iakova, P.2
Wilde, M.3
Awad, S.4
-
62
-
-
84884252657
-
A tetrahydroisoquinoline alkaloid THI-28 reduces LPS-induced HMGB1 and diminishes organ injury in septic mice through p38 and PI3K/Nrf2/HO-1 signals
-
Kim, H. S., Park, E. J., Park, S. W., Kim, H. J. et al., A tetrahydroisoquinoline alkaloid THI-28 reduces LPS-induced HMGB1 and diminishes organ injury in septic mice through p38 and PI3K/Nrf2/HO-1 signals. Int. Immunopharmacol. 2013, 17, 684-692.
-
(2013)
Int. Immunopharmacol.
, vol.17
, pp. 684-692
-
-
Kim, H.S.1
Park, E.J.2
Park, S.W.3
Kim, H.J.4
-
63
-
-
84890508650
-
Inhibitory effects of baicalin in the early stage of 3T3-L1 preadipocytes differentiation by down-regulation of PDK1/Akt phosphorylation
-
Kwak, D. H., Lee, J. H., Song, K. H., Ma, J. Y., Inhibitory effects of baicalin in the early stage of 3T3-L1 preadipocytes differentiation by down-regulation of PDK1/Akt phosphorylation. Mol. Cell. Biochem. 2014, 385, 257-264.
-
(2014)
Mol. Cell. Biochem.
, vol.385
, pp. 257-264
-
-
Kwak, D.H.1
Lee, J.H.2
Song, K.H.3
Ma, J.Y.4
-
64
-
-
84924634426
-
The flavones apigenin and luteolin induce FOXO1 translocation but inhibit gluconeogenic and lipogenic gene expression in human cells
-
Bumke-Vogt, C., Osterhoff, M. A., Borchert, A., Guzman-Perez, V. et al., The flavones apigenin and luteolin induce FOXO1 translocation but inhibit gluconeogenic and lipogenic gene expression in human cells. PLoS One 2014, 9, e104321.
-
(2014)
PLoS One
, vol.9
, pp. e104321
-
-
Bumke-Vogt, C.1
Osterhoff, M.A.2
Borchert, A.3
Guzman-Perez, V.4
-
65
-
-
0036787393
-
Insulin stimulates long-chain fatty acid utilization by rat cardiac myocytes through cellular redistribution of FAT/CD36
-
Luiken, J. J., Koonen, D. P., Willems, J., Zorzano, A. et al., Insulin stimulates long-chain fatty acid utilization by rat cardiac myocytes through cellular redistribution of FAT/CD36. Diabetes 2002, 51, 3113-3119.
-
(2002)
Diabetes
, vol.51
, pp. 3113-3119
-
-
Luiken, J.J.1
Koonen, D.P.2
Willems, J.3
Zorzano, A.4
-
66
-
-
78649746191
-
Transcription factor Nrf2 regulates SHP and lipogenic gene expression in hepatic lipid metabolism
-
Huang, J., Tabbi-Anneni, I., Gunda, V., Wang, L., Transcription factor Nrf2 regulates SHP and lipogenic gene expression in hepatic lipid metabolism. Am. J. Physiol. Gastrointest. Liver Physiol. 2010, 299, G1211-G1221.
-
(2010)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.299
, pp. G1211-G1221
-
-
Huang, J.1
Tabbi-Anneni, I.2
Gunda, V.3
Wang, L.4
-
67
-
-
34547097746
-
Hepatitis C virus induces proteolytic cleavage of sterol regulatory element binding proteins and stimulates their phosphorylation via oxidative stress
-
Waris, G., Felmlee, D. J., Negro, F., Siddiqui, A., Hepatitis C virus induces proteolytic cleavage of sterol regulatory element binding proteins and stimulates their phosphorylation via oxidative stress. J. Virol. 2007, 81, 8122-8130.
-
(2007)
J. Virol.
, vol.81
, pp. 8122-8130
-
-
Waris, G.1
Felmlee, D.J.2
Negro, F.3
Siddiqui, A.4
|