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Volumn 46, Issue 1, 2007, Pages 1-5

A little orphan runs to fat: The orphan receptor small heterodimer partner as a key player in the regulation of hepatic lipid metabolism

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

EID: 34547476712     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21801     Document Type: Editorial
Times cited : (11)

References (28)
  • 1
    • 33644547706 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: From steatosis to cirrhosis
    • Farrell GC, Larter CZ. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. HEPATOLOGY 2006;43(Suppl 1):S99-S112.
    • (2006) HEPATOLOGY , vol.43 , Issue.SUPPL. 1
    • Farrell, G.C.1    Larter, C.Z.2
  • 2
    • 33847789529 scopus 로고    scopus 로고
    • Drugs improving insulin resistance for non-alcoholic fatty liver disease and/or non-alcoholic steatohepatitis
    • CD005166
    • Angelico F, Burattin M, Alessandri C, Del Ben M, Lirussi F. Drugs improving insulin resistance for non-alcoholic fatty liver disease and/or non-alcoholic steatohepatitis. Cochrane Database Syst Rev 2007;(1):CD005166.
    • (2007) Cochrane Database Syst Rev , Issue.1
    • Angelico, F.1    Burattin, M.2    Alessandri, C.3    Del Ben, M.4    Lirussi, F.5
  • 3
    • 4043077961 scopus 로고    scopus 로고
    • Molecular mediators of hepatic steatosis and liver injury
    • Browning JD, Horton JD. Molecular mediators of hepatic steatosis and liver injury. J Clin Invest 2004;114:147-152.
    • (2004) J Clin Invest , vol.114 , pp. 147-152
    • Browning, J.D.1    Horton, J.D.2
  • 4
    • 34547411540 scopus 로고    scopus 로고
    • Molecular characterization of the role of orphan receptor small heterodimer partner in development of fatty liver
    • Huang J, Iqbal J, Saha PK, Liu J, Chan L, Hussain MM, et al. Molecular characterization of the role of orphan receptor small heterodimer partner in development of fatty liver. HEPATOLOGY 2007;46:147-157.
    • (2007) HEPATOLOGY , vol.46 , pp. 147-157
    • Huang, J.1    Iqbal, J.2    Saha, P.K.3    Liu, J.4    Chan, L.5    Hussain, M.M.6
  • 5
    • 23444431623 scopus 로고    scopus 로고
    • Retinoid x receptor heterodimers in the metabolic syndrome
    • Shulman AI, Mangelsdorf DJ. Retinoid x receptor heterodimers in the metabolic syndrome. N Engl J Med 2005;353:604-615.
    • (2005) N Engl J Med , vol.353 , pp. 604-615
    • Shulman, A.I.1    Mangelsdorf, D.J.2
  • 6
    • 0036623233 scopus 로고    scopus 로고
    • Nuclear receptor regulation of hepatic function
    • Karpen SJ. Nuclear receptor regulation of hepatic function. J Hepatol 2002;36:832-850.
    • (2002) J Hepatol , vol.36 , pp. 832-850
    • Karpen, S.J.1
  • 7
    • 27844509037 scopus 로고    scopus 로고
    • Transcriptional corepression by SHP: Molecular mechanisms and physiological consequences
    • Bavner A, Sanyal S, Gustafsson JA, Treuter E. Transcriptional corepression by SHP: molecular mechanisms and physiological consequences. Trends Endocrinol Metab 2005;16:478-488.
    • (2005) Trends Endocrinol Metab , vol.16 , pp. 478-488
    • Bavner, A.1    Sanyal, S.2    Gustafsson, J.A.3    Treuter, E.4
  • 8
    • 27844551588 scopus 로고    scopus 로고
    • The orphan nuclear receptor SHP regulates PGC-1 alpha expression and energy production in brown adipocytes
    • Wang L, Liu J, Saha P, Huang J, Chan L, Spiegelman B, et al. The orphan nuclear receptor SHP regulates PGC-1 alpha expression and energy production in brown adipocytes. Cell Metab 2005;2:227-238.
    • (2005) Cell Metab , vol.2 , pp. 227-238
    • Wang, L.1    Liu, J.2    Saha, P.3    Huang, J.4    Chan, L.5    Spiegelman, B.6
  • 9
    • 33751530003 scopus 로고    scopus 로고
    • Orphan receptor small heterodimer partner is an important mediator of glucose homeostasis
    • Wang L, Huang J, Saha P, Kulkarni RN, Hu M, Kim Y, et al. Orphan receptor small heterodimer partner is an important mediator of glucose homeostasis. Mol Endocrinol 2006;20:2671-2681.
    • (2006) Mol Endocrinol , vol.20 , pp. 2671-2681
    • Wang, L.1    Huang, J.2    Saha, P.3    Kulkarni, R.N.4    Hu, M.5    Kim, Y.6
  • 11
    • 0037059762 scopus 로고    scopus 로고
    • Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation
    • Nishizawa H, Yamagata K, Shimomura I, Takahashi M, Kuriyama H, Kishida K, et al. Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation. J Biol Chem 2002;277:1586-1592.
    • (2002) J Biol Chem , vol.277 , pp. 1586-1592
    • Nishizawa, H.1    Yamagata, K.2    Shimomura, I.3    Takahashi, M.4    Kuriyama, H.5    Kishida, K.6
  • 12
    • 0242582371 scopus 로고    scopus 로고
    • Resistance of SHP-null mice to bile acid-induced liver damage
    • Wang L, Han Y, Kim CS, Lee YK, Moore DD. Resistance of SHP-null mice to bile acid-induced liver damage. J Biol Chem 2003;278:44475-44481.
    • (2003) J Biol Chem , vol.278 , pp. 44475-44481
    • Wang, L.1    Han, Y.2    Kim, C.S.3    Lee, Y.K.4    Moore, D.D.5
  • 15
    • 0038509036 scopus 로고    scopus 로고
    • Lipotoxicity: When tissues overeat
    • Schaffer JE. Lipotoxicity: when tissues overeat. Curr Opin Lipidol 2003;14:281-287.
    • (2003) Curr Opin Lipidol , vol.14 , pp. 281-287
    • Schaffer, J.E.1
  • 16
    • 8544256355 scopus 로고    scopus 로고
    • Bile acid reduces the secretion of very low density lipoprotein by repressing microsomal triglyceride transfer protein gene expression mediated by hepatocyte nuclear factor-4
    • Hirokane H, Nakahara M, Tachibana S, Shimizu M, Sato R. Bile acid reduces the secretion of very low density lipoprotein by repressing microsomal triglyceride transfer protein gene expression mediated by hepatocyte nuclear factor-4. J Biol Chem 2004;279:45685-45692.
    • (2004) J Biol Chem , vol.279 , pp. 45685-45692
    • Hirokane, H.1    Nakahara, M.2    Tachibana, S.3    Shimizu, M.4    Sato, R.5
  • 17
    • 33846500153 scopus 로고    scopus 로고
    • Putz-Bankuti C, Datz C, Marz W, Lackner C, Stauber RE, Trauner M, et al. Clinical-pathological conference series from the Medical University of Graz: case no. 131: elevated transaminases in a 30-year-old male. Wien Klin Wochenschr 2006;118:769-775.
    • Putz-Bankuti C, Datz C, Marz W, Lackner C, Stauber RE, Trauner M, et al. Clinical-pathological conference series from the Medical University of Graz: case no. 131: elevated transaminases in a 30-year-old male. Wien Klin Wochenschr 2006;118:769-775.
  • 18
    • 18244365866 scopus 로고    scopus 로고
    • Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: A model of viral-related steatosis
    • Perlemuter G, Sabile A, Letteron P, Vona G, Topilco A, Chretien Y, et al. Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis. FASEB J 2002;16:185-194.
    • (2002) FASEB J , vol.16 , pp. 185-194
    • Perlemuter, G.1    Sabile, A.2    Letteron, P.3    Vona, G.4    Topilco, A.5    Chretien, Y.6
  • 19
    • 26244441014 scopus 로고    scopus 로고
    • The farnesoid X receptor: A molecular link berween bile acid and lipid and glucose metabolism
    • Claudel T, Staels B, Kuipers F. The farnesoid X receptor: a molecular link berween bile acid and lipid and glucose metabolism. Arterioscler Thromb Vasc Biol 2005;25:2020-2030.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2020-2030
    • Claudel, T.1    Staels, B.2    Kuipers, F.3
  • 20
    • 33645509321 scopus 로고    scopus 로고
    • Farnesoid X receptor is essential for normal glucose homeostasis
    • Ma K, Saha PK, Chan L, Moore DD. Farnesoid X receptor is essential for normal glucose homeostasis. J Clin Invest 2006;116:1102-1109.
    • (2006) J Clin Invest , vol.116 , pp. 1102-1109
    • Ma, K.1    Saha, P.K.2    Chan, L.3    Moore, D.D.4
  • 21
    • 32244447570 scopus 로고    scopus 로고
    • Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice
    • Zhang Y, Lee FY, Barrera G, Lee H, Vales C, Gonzalez FJ, et al. Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice. Proc Natl Acad Sci U S A 2006;103:1006-1011.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 1006-1011
    • Zhang, Y.1    Lee, F.Y.2    Barrera, G.3    Lee, H.4    Vales, C.5    Gonzalez, F.J.6
  • 23
    • 18244382304 scopus 로고    scopus 로고
    • Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
    • Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest 2005;115:1343-1351.
    • (2005) J Clin Invest , vol.115 , pp. 1343-1351
    • Donnelly, K.L.1    Smith, C.I.2    Schwarzenberg, S.J.3    Jessurun, J.4    Boldt, M.D.5    Parks, E.J.6
  • 25
    • 0035895268 scopus 로고    scopus 로고
    • Mutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjects
    • Nishigori H, Tomura H, Tonooka N, Kanamori M, Yamada S, Sho K, et al. Mutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjects. Proc Natl Acad Sci U S A 2001;98:575-580.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 575-580
    • Nishigori, H.1    Tomura, H.2    Tonooka, N.3    Kanamori, M.4    Yamada, S.5    Sho, K.6
  • 26
    • 12444293733 scopus 로고    scopus 로고
    • Contribution of variants in the small heterodimer partner gene to birthweight, adiposity, and insulin levels: Mutational analysis and association studies in multiple populations
    • Hung CC, Farooqi IS, Ong K, Luan J, Keogh JM, Pembrey M, et al. Contribution of variants in the small heterodimer partner gene to birthweight, adiposity, and insulin levels: mutational analysis and association studies in multiple populations. Diabetes 2003;52:1288-1291.
    • (2003) Diabetes , vol.52 , pp. 1288-1291
    • Hung, C.C.1    Farooqi, I.S.2    Ong, K.3    Luan, J.4    Keogh, J.M.5    Pembrey, M.6
  • 27
    • 7644244675 scopus 로고    scopus 로고
    • The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis
    • Fiorucci S, Antonelli E, Rizzo G, Renga B, Mencarelli A, Riccardi L, et al. The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis. Gastroenterology 2004;127:1497-1512.
    • (2004) Gastroenterology , vol.127 , pp. 1497-1512
    • Fiorucci, S.1    Antonelli, E.2    Rizzo, G.3    Renga, B.4    Mencarelli, A.5    Riccardi, L.6
  • 28
    • 34248657027 scopus 로고    scopus 로고
    • Polymorphism in microsomal triglyceride transfer protein: A link between liver disease and atherogenic postprandial lipid profile in NASH?
    • Gambino R, Cassader M, Pagano G, Durazzo M, Musso G. Polymorphism in microsomal triglyceride transfer protein: a link between liver disease and atherogenic postprandial lipid profile in NASH? HEPATOLOGY 2007;45:1097-1107.
    • (2007) HEPATOLOGY , vol.45 , pp. 1097-1107
    • Gambino, R.1    Cassader, M.2    Pagano, G.3    Durazzo, M.4    Musso, G.5


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