메뉴 건너뛰기




Volumn 16, Issue 1, 2015, Pages

Small RNAs derived from tRNAs and rRNAs are highly enriched in exosomes from both old and new world Leishmania providing evidence for conserved exosomal RNA Packaging

Author keywords

Exosomes; Leishmania; Shuttle RNA; Small non coding RNA; tRNA derived small RNA

Indexed keywords

RIBONUCLEASE; RIBOSOME RNA; SMALL INTERFERING RNA; TRANSFER RNA; MESSENGER RNA; MICRORNA; SMALL UNTRANSLATED RNA;

EID: 84928729816     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/s12864-015-1260-7     Document Type: Article
Times cited : (119)

References (82)
  • 1
    • 9144220867 scopus 로고    scopus 로고
    • Cutting edge: neutrophil granulocyte serves as a vector for Leishmania entry into macrophages
    • van Zandbergen G, Klinger M, Mueller A, Dannenberg S, Gebert A, Solbach W, et al. Cutting edge: neutrophil granulocyte serves as a vector for Leishmania entry into macrophages. J Immunol. 2004;173:6521-5.
    • (2004) J Immunol , vol.173 , pp. 6521-6525
    • Zandbergen, G.1    Klinger, M.2    Mueller, A.3    Dannenberg, S.4    Gebert, A.5    Solbach, W.6
  • 2
    • 0037146607 scopus 로고    scopus 로고
    • Leishmania EF-1alpha activates the Src homology 2 domain containing tyrosine phosphatase SHP-1 leading to macrophage deactivation
    • Nandan D, Yi T, Lopez M, Lai C, Reiner NE. Leishmania EF-1alpha activates the Src homology 2 domain containing tyrosine phosphatase SHP-1 leading to macrophage deactivation. J Biol Chem. 2002;277:50190-7.
    • (2002) J Biol Chem , vol.277 , pp. 50190-50197
    • Nandan, D.1    Yi, T.2    Lopez, M.3    Lai, C.4    Reiner, N.E.5
  • 3
    • 0032792689 scopus 로고    scopus 로고
    • Activation of phosphotyrosine phosphatase activity attenuates mitogen-activated protein kinase signaling and inhibits c-FOS and nitric oxide synthase expression in macrophages infected with Leishmania donovani
    • Nandan D, Lo R, Reiner NE. Activation of phosphotyrosine phosphatase activity attenuates mitogen-activated protein kinase signaling and inhibits c-FOS and nitric oxide synthase expression in macrophages infected with Leishmania donovani. Infect Immun. 1999;67:4055-63.
    • (1999) Infect Immun , vol.67 , pp. 4055-4063
    • Nandan, D.1    Lo, R.2    Reiner, N.E.3
  • 4
    • 0036717724 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase attenuates Leishmania donovani infection in macrophages
    • Junghae M, Raynes JG. Activation of p38 mitogen-activated protein kinase attenuates Leishmania donovani infection in macrophages. Infect Immun. 2002;70:5026-35.
    • (2002) Infect Immun , vol.70 , pp. 5026-5035
    • Junghae, M.1    Raynes, J.G.2
  • 7
    • 77951152406 scopus 로고    scopus 로고
    • An exosome-based secretion pathway is responsible for protein export from Leishmania and communication with macrophages
    • Silverman JM, Clos J, de'Oliveira CC, Shirvani O, Fang Y, Wang C, et al. An exosome-based secretion pathway is responsible for protein export from Leishmania and communication with macrophages. J Cell Sci. 2010;123:842-52.
    • (2010) J Cell Sci , vol.123 , pp. 842-852
    • Silverman, J.M.1    Clos, J.2    de'Oliveira, C.C.3    Shirvani, O.4    Fang, Y.5    Wang, C.6
  • 8
  • 9
    • 78650265541 scopus 로고    scopus 로고
    • Exosomes and other microvesicles in infection biology: organelles with unanticipated phenotypes
    • Silverman JM, Reiner NE. Exosomes and other microvesicles in infection biology: organelles with unanticipated phenotypes. Cell Microbiol. 2011;13:1-9.
    • (2011) Cell Microbiol , vol.13 , pp. 1-9
    • Silverman, J.M.1    Reiner, N.E.2
  • 11
    • 77956128614 scopus 로고    scopus 로고
    • Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages
    • Giri PK, Kruh NA, Dobos KM, Schorey JS. Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages. Proteomics. 2010;10:1-13.
    • (2010) Proteomics , vol.10 , pp. 1-13
    • Giri, P.K.1    Kruh, N.A.2    Dobos, K.M.3    Schorey, J.S.4
  • 12
    • 84919455345 scopus 로고    scopus 로고
    • Toxoplasma gondii infection of fibroblasts causes the production of exosome-like vesicles containing a unique array of mRNA and miRNA transcripts compared to serum starvation
    • Pope SM, Lasser C. Toxoplasma gondii infection of fibroblasts causes the production of exosome-like vesicles containing a unique array of mRNA and miRNA transcripts compared to serum starvation. J Extracell Vesicles. 2013;2:22484.
    • (2013) J Extracell Vesicles , vol.2 , pp. 22484
    • Pope, S.M.1    Lasser, C.2
  • 13
    • 84877855333 scopus 로고    scopus 로고
    • Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system
    • Mantel PY, Hoang AN, Goldowitz I, Potashnikova D, Hamza B, Vorobjev I, et al. Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system. Cell Host Microbe. 2013;13:521-34.
    • (2013) Cell Host Microbe , vol.13 , pp. 521-534
    • Mantel, P.Y.1    Hoang, A.N.2    Goldowitz, I.3    Potashnikova, D.4    Hamza, B.5    Vorobjev, I.6
  • 14
  • 15
    • 60649113108 scopus 로고    scopus 로고
    • Sec6-dependent sorting of fungal extracellular exosomes and laccase of Cryptococcus neoformans
    • Panepinto J, Komperda K, Frases S, Park YD, Djordjevic JT, Casadevall A, et al. Sec6-dependent sorting of fungal extracellular exosomes and laccase of Cryptococcus neoformans. Mol Microbiol. 2009;71:1165-76.
    • (2009) Mol Microbiol , vol.71 , pp. 1165-1176
    • Panepinto, J.1    Komperda, K.2    Frases, S.3    Park, Y.D.4    Djordjevic, J.T.5    Casadevall, A.6
  • 16
    • 84873348534 scopus 로고    scopus 로고
    • Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins
    • Bayer-Santos E, Guilar-Bonavides C, Rodrigues SP, Cordero EM, Marques AF, Varela-Ramirez A, et al. Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. J Proteome Res. 2013;12:883-97.
    • (2013) J Proteome Res , vol.12 , pp. 883-897
    • Bayer-Santos, E.1    Guilar-Bonavides, C.2    Rodrigues, S.P.3    Cordero, E.M.4    Marques, A.F.5    Varela-Ramirez, A.6
  • 17
    • 84891839815 scopus 로고    scopus 로고
    • Extracellular vesicles shed by Trypanosoma cruzi are linked to small RNA pathways, life cycle regulation, and susceptibility to infection of mammalian cells
    • Garcia-Silva MR, das Neves RF, Cabrera-Cabrera F, Sanguinetti J, Medeiros LC, Robello C, et al. Extracellular vesicles shed by Trypanosoma cruzi are linked to small RNA pathways, life cycle regulation, and susceptibility to infection of mammalian cells. Parasitol Res. 2014;113:285-304.
    • (2014) Parasitol Res , vol.113 , pp. 285-304
    • Garcia-Silva, M.R.1    das Neves, R.F.2    Cabrera-Cabrera, F.3    Sanguinetti, J.4    Medeiros, L.C.5    Robello, C.6
  • 18
    • 78149480920 scopus 로고    scopus 로고
    • Leishmania exosomes modulate innate and adaptive immune responses through effects on monocytes and dendritic cells
    • Silverman JM, Clos J, Horakova E, Wang AY, Wiesgigl M, Kelly I, et al. Leishmania exosomes modulate innate and adaptive immune responses through effects on monocytes and dendritic cells. J Immunol. 2010;185:5011-22.
    • (2010) J Immunol , vol.185 , pp. 5011-5022
    • Silverman, J.M.1    Clos, J.2    Horakova, E.3    Wang, A.Y.4    Wiesgigl, M.5    Kelly, I.6
  • 19
    • 84875169603 scopus 로고    scopus 로고
    • Leishmania donovani targets Dicer1 to downregulate miR-122, lower serum cholesterol, and facilitate murine liver infection
    • Ghosh J, Bose M, Roy S, Bhattacharyya SN. Leishmania donovani targets Dicer1 to downregulate miR-122, lower serum cholesterol, and facilitate murine liver infection. Cell Host Microbe. 2013;13:277-88.
    • (2013) Cell Host Microbe , vol.13 , pp. 277-288
    • Ghosh, J.1    Bose, M.2    Roy, S.3    Bhattacharyya, S.N.4
  • 20
    • 84899674650 scopus 로고    scopus 로고
    • Absence of metalloprotease GP63 alters the protein content of Leishmania exosomes
    • Hassani K, Shio MT, Martel C, Faubert D, Olivier M. Absence of metalloprotease GP63 alters the protein content of Leishmania exosomes. PLoS One. 2014;9:e95007.
    • (2014) PLoS One , vol.9 , pp. e95007
    • Hassani, K.1    Shio, M.T.2    Martel, C.3    Faubert, D.4    Olivier, M.5
  • 21
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol. 2007;9:654-9.
    • (2007) Nat Cell Biol , vol.9 , pp. 654-659
    • Valadi, H.1    Ekstrom, K.2    Bossios, A.3    Sjostrand, M.4    Lee, J.J.5    Lotvall, J.O.6
  • 22
    • 84884737398 scopus 로고    scopus 로고
    • Trichomonas vaginalis exosomes deliver cargo to host cells and mediate hostratioparasite interactions
    • Twu O, de Miguel N, Lustig G, Stevens GC, Vashisht AA, Wohlschlegel JA, et al. Trichomonas vaginalis exosomes deliver cargo to host cells and mediate hostratioparasite interactions. PLoS Pathog. 2013;9:e1003482.
    • (2013) PLoS Pathog , vol.9 , pp. e1003482
    • Twu, O.1    de Miguel, N.2    Lustig, G.3    Stevens, G.C.4    Vashisht, A.A.5    Wohlschlegel, J.A.6
  • 23
    • 84893915361 scopus 로고    scopus 로고
    • A particular set of small non-coding RNAs is bound to the distinctive Argonaute protein of Trypanosoma cruzi: insights from RNA-interference deficient organisms
    • Garcia-Silva MR, Sanguinetti J, Cabrera-Cabrera F, Franzen O, Cayota A. A particular set of small non-coding RNAs is bound to the distinctive Argonaute protein of Trypanosoma cruzi: insights from RNA-interference deficient organisms. Gene. 2014;538:379-84.
    • (2014) Gene , vol.538 , pp. 379-384
    • Garcia-Silva, M.R.1    Sanguinetti, J.2    Cabrera-Cabrera, F.3    Franzen, O.4    Cayota, A.5
  • 24
    • 78449245604 scopus 로고    scopus 로고
    • Retention and loss of RNA interference pathways in trypanosomatid protozoans
    • Lye LF, Owens K, Shi H, Murta SM, Vieira AC, Turco SJ, et al. Retention and loss of RNA interference pathways in trypanosomatid protozoans. PLoS Pathog. 2010;6:e1001161.
    • (2010) PLoS Pathog , vol.6 , pp. e1001161
    • Lye, L.F.1    Owens, K.2    Shi, H.3    Murta, S.M.4    Vieira, A.C.5    Turco, S.J.6
  • 25
    • 79955941135 scopus 로고    scopus 로고
    • Evidence of RNA editing in Leishmania braziliensis promastigotes
    • Ramirez C, Puerta C, Requena JM. Evidence of RNA editing in Leishmania braziliensis promastigotes. Parasitol Res. 2011;108:731-9.
    • (2011) Parasitol Res , vol.108 , pp. 731-739
    • Ramirez, C.1    Puerta, C.2    Requena, J.M.3
  • 26
    • 77954761604 scopus 로고    scopus 로고
    • Complete set of mitochondrial pan-edited mRNAs in Leishmania mexicana amazonensis LV78
    • Maslov DA. Complete set of mitochondrial pan-edited mRNAs in Leishmania mexicana amazonensis LV78. Mol Biochem Parasitol. 2010;173:107-14.
    • (2010) Mol Biochem Parasitol , vol.173 , pp. 107-114
    • Maslov, D.A.1
  • 27
    • 84857188863 scopus 로고    scopus 로고
    • Artemis: an integrated platform for visualization and analysis of high-throughput sequence-based experimental data
    • Carver T, Harris SR, Berriman M, Parkhill J, McQuillan JA. Artemis: an integrated platform for visualization and analysis of high-throughput sequence-based experimental data. Bioinformatics. 2012;28:464-9.
    • (2012) Bioinformatics , vol.28 , pp. 464-469
    • Carver, T.1    Harris, S.R.2    Berriman, M.3    Parkhill, J.4    McQuillan, J.A.5
  • 30
    • 84857692673 scopus 로고    scopus 로고
    • Transfer RNA-derived fragments: origins, processing, and functions
    • Sobala A, Hutvagner G. Transfer RNA-derived fragments: origins, processing, and functions. Wiley Interdiscip Rev RNA. 2011;2:853-62.
    • (2011) Wiley Interdiscip Rev RNA , vol.2 , pp. 853-862
    • Sobala, A.1    Hutvagner, G.2
  • 31
    • 33748346026 scopus 로고    scopus 로고
    • Perfect seed pairing is not a generally reliable predictor for miRNA-target interactions
    • Didiano D, Hobert O. Perfect seed pairing is not a generally reliable predictor for miRNA-target interactions. Nat Struct Mol Biol. 2006;13:849-51.
    • (2006) Nat Struct Mol Biol , vol.13 , pp. 849-851
    • Didiano, D.1    Hobert, O.2
  • 32
    • 84873059935 scopus 로고    scopus 로고
    • The structure and repertoire of small interfering RNAs in Leishmania (Viannia) braziliensis reveal diversification in the trypanosomatid RNAi pathway
    • Atayde VD, Shi H, Franklin JB, Carriero N, Notton T, Lye LF, et al. The structure and repertoire of small interfering RNAs in Leishmania (Viannia) braziliensis reveal diversification in the trypanosomatid RNAi pathway. Mol Microbiol. 2013;87:580-93.
    • (2013) Mol Microbiol , vol.87 , pp. 580-593
    • Atayde, V.D.1    Shi, H.2    Franklin, J.B.3    Carriero, N.4    Notton, T.5    Lye, L.F.6
  • 33
    • 34347339518 scopus 로고    scopus 로고
    • Comparative genomic analysis of three Leishmania species that cause diverse human disease
    • Peacock CS, Seeger K, Harris D, Murphy L, Ruiz JC, Quail MA, et al. Comparative genomic analysis of three Leishmania species that cause diverse human disease. Nat Genet. 2007;39:839-47.
    • (2007) Nat Genet , vol.39 , pp. 839-847
    • Peacock, C.S.1    Seeger, K.2    Harris, D.3    Murphy, L.4    Ruiz, J.C.5    Quail, M.A.6
  • 34
    • 0032077508 scopus 로고    scopus 로고
    • Characterisation of Leishmania telomeres reveals unusual telomeric repeats and conserved telomere-associated sequence
    • Fu G, Barker DC. Characterisation of Leishmania telomeres reveals unusual telomeric repeats and conserved telomere-associated sequence. Nucleic Acids Res. 1998;26:2161-7.
    • (1998) Nucleic Acids Res , vol.26 , pp. 2161-2167
    • Fu, G.1    Barker, D.C.2
  • 35
    • 84870599244 scopus 로고    scopus 로고
    • Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells
    • Bellingham SA, Coleman BM, Hill AF. Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Nucleic Acids Res. 2012;40:10937-49.
    • (2012) Nucleic Acids Res , vol.40 , pp. 10937-10949
    • Bellingham, S.A.1    Coleman, B.M.2    Hill, A.F.3
  • 36
    • 84867546396 scopus 로고    scopus 로고
    • Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions
    • Nolte-'t Hoen EN, Buermans HP, Waasdorp M, Stoorvogel W, Wauben MH, 't Hoen PA, et al. Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions. Nucleic Acids Res. 2012;40:9272-85.
    • (2012) Nucleic Acids Res , vol.40 , pp. 9272-9285
    • Nolte-'t Hoen, E.N.1    Buermans, H.P.2    Waasdorp, M.3    Stoorvogel, W.4    Wauben, M.H.5    't Hoen, P.A.6
  • 37
    • 84877298502 scopus 로고    scopus 로고
    • Characterization of human plasma-derived exosomal RNAs by deep sequencing
    • Huang X, Yuan T, Tschannen M, Sun Z, Jacob H, Du M, et al. Characterization of human plasma-derived exosomal RNAs by deep sequencing. BMC Genomics. 2013;14:319.
    • (2013) BMC Genomics , vol.14 , pp. 319
    • Huang, X.1    Yuan, T.2    Tschannen, M.3    Sun, Z.4    Jacob, H.5    Du, M.6
  • 38
    • 58149189877 scopus 로고    scopus 로고
    • GtRNAdb: a database of transfer RNA genes detected in genomic sequence
    • Chan PP, Lowe TM. GtRNAdb: a database of transfer RNA genes detected in genomic sequence. Nucleic Acids Res. 2009;37:D93-7.
    • (2009) Nucleic Acids Res , vol.37 , pp. D93-D97
    • Chan, P.P.1    Lowe, T.M.2
  • 39
    • 84901261496 scopus 로고    scopus 로고
    • Massively parallel sequencing of human urinary exosome/microvesicle RNA reveals a predominance of non-coding RNA
    • Miranda KC, Bond DT, Levin JZ, Adiconis X, Sivachenko A, Russ C, et al. Massively parallel sequencing of human urinary exosome/microvesicle RNA reveals a predominance of non-coding RNA. PLoS One. 2014;9:e96094.
    • (2014) PLoS One , vol.9 , pp. e96094
    • Miranda, K.C.1    Bond, D.T.2    Levin, J.Z.3    Adiconis, X.4    Sivachenko, A.5    Russ, C.6
  • 42
    • 84903160226 scopus 로고    scopus 로고
    • Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions
    • Vojtech L, Woo S, Hughes S, Levy C, Ballweber L, Sauteraud RP, et al. Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions. Nucleic Acids Res. 2014;42:7290-304.
    • (2014) Nucleic Acids Res , vol.42 , pp. 7290-7304
    • Vojtech, L.1    Woo, S.2    Hughes, S.3    Levy, C.4    Ballweber, L.5    Sauteraud, R.P.6
  • 43
    • 84885577882 scopus 로고    scopus 로고
    • The complete exosome workflow solution: from isolation to characterization of RNA cargo
    • Schageman J, Zeringer E, Li M, Barta T, Lea K, Gu J, et al. The complete exosome workflow solution: from isolation to characterization of RNA cargo. Biomed Res Int. 2013;2013:253957.
    • (2013) Biomed Res Int , vol.2013 , pp. 253957
    • Schageman, J.1    Zeringer, E.2    Li, M.3    Barta, T.4    Lea, K.5    Gu, J.6
  • 45
    • 84904704297 scopus 로고    scopus 로고
    • Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles
    • Colombo M, Raposo G, Thery C. Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. Annu Rev Cell Dev Biol. 2014;30:255-89.
    • (2014) Annu Rev Cell Dev Biol , vol.30 , pp. 255-289
    • Colombo, M.1    Raposo, G.2    Thery, C.3
  • 46
    • 84901833952 scopus 로고    scopus 로고
    • Surface analysis of Dicrocoelium dendriticum. The molecular characterization of exosomes reveals the presence of miRNAs
    • Bernal D, Trelis M, Montaner S, Cantalapiedra F, Galiano A, Hackenberg M, et al. Surface analysis of Dicrocoelium dendriticum. The molecular characterization of exosomes reveals the presence of miRNAs. J Proteomics. 2014;105:232-41.
    • (2014) J Proteomics , vol.105 , pp. 232-241
    • Bernal, D.1    Trelis, M.2    Montaner, S.3    Cantalapiedra, F.4    Galiano, A.5    Hackenberg, M.6
  • 47
    • 84921530965 scopus 로고    scopus 로고
    • Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity
    • Buck AH, Coakley G, Simbari F, McSorley HJ, Quintana JF, Le BT, et al. Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. Nat Commun. 2014;5:5488.
    • (2014) Nat Commun , vol.5 , pp. 5488
    • Buck, A.H.1    Coakley, G.2    Simbari, F.3    McSorley, H.J.4    Quintana, J.F.5    Le, B.T.6
  • 49
    • 70349652191 scopus 로고    scopus 로고
    • The non-coding RNA of the multidrug resistance-linked vault particle encodes multiple regulatory small RNAs
    • Persson H, Kvist A, Vallon-Christersson J, Medstrand P, Borg A, Rovira C. The non-coding RNA of the multidrug resistance-linked vault particle encodes multiple regulatory small RNAs. Nat Cell Biol. 2009;11:1268-71.
    • (2009) Nat Cell Biol , vol.11 , pp. 1268-1271
    • Persson, H.1    Kvist, A.2    Vallon-Christersson, J.3    Medstrand, P.4    Borg, A.5    Rovira, C.6
  • 50
    • 77950202393 scopus 로고    scopus 로고
    • Human tRNA-derived small RNAs in the global regulation of RNA silencing
    • Haussecker D, Huang Y, Lau A, Parameswaran P, Fire AZ, Kay MA. Human tRNA-derived small RNAs in the global regulation of RNA silencing. RNA. 2010;16:673-95.
    • (2010) RNA , vol.16 , pp. 673-695
    • Haussecker, D.1    Huang, Y.2    Lau, A.3    Parameswaran, P.4    Fire, A.Z.5    Kay, M.A.6
  • 51
    • 84870975709 scopus 로고    scopus 로고
    • Processing of snoRNAs as a new source of regulatory non-coding RNAs: snoRNA fragments form a new class of functional RNAs
    • Falaleeva M, Stamm S. Processing of snoRNAs as a new source of regulatory non-coding RNAs: snoRNA fragments form a new class of functional RNAs. Bioessays. 2013;35:46-54.
    • (2013) Bioessays , vol.35 , pp. 46-54
    • Falaleeva, M.1    Stamm, S.2
  • 54
    • 84885101782 scopus 로고    scopus 로고
    • Genome-wide analysis of 3'-untranslated regions supports the existence of post-transcriptional regulons controlling gene expression in trypanosomes
    • De Gaudenzi JG, Carmona SJ, Aguero F, Frasch AC. Genome-wide analysis of 3'-untranslated regions supports the existence of post-transcriptional regulons controlling gene expression in trypanosomes. Peer J. 2013;1:e118.
    • (2013) Peer J , vol.1 , pp. e118
    • Gaudenzi, J.G.1    Carmona, S.J.2    Aguero, F.3    Frasch, A.C.4
  • 55
    • 0035860828 scopus 로고    scopus 로고
    • TcUBP-1, a developmentally regulated U-rich RNA-binding protein involved in selective mRNA destabilization in trypanosomes
    • D'Orso I, Frasch AC. TcUBP-1, a developmentally regulated U-rich RNA-binding protein involved in selective mRNA destabilization in trypanosomes. J Biol Chem. 2001;276:34801-9.
    • (2001) J Biol Chem , vol.276 , pp. 34801-34809
    • D'Orso, I.1    Frasch, A.C.2
  • 56
    • 61449182673 scopus 로고    scopus 로고
    • Differential trypanosome surface coat regulation by a CCCH protein that co-associates with procyclin mRNA cis-elements
    • Walrad P, Paterou A, Costa-Serrano A, Matthews KR. Differential trypanosome surface coat regulation by a CCCH protein that co-associates with procyclin mRNA cis-elements. PLoS Pathog. 2009;5:e1000317.
    • (2009) PLoS Pathog , vol.5 , pp. e1000317
    • Walrad, P.1    Paterou, A.2    Costa-Serrano, A.3    Matthews, K.R.4
  • 57
    • 77956226465 scopus 로고    scopus 로고
    • Cloning, characterization and subcellular localization of a Trypanosoma cruzi argonaute protein defining a new subfamily distinctive of trypanosomatids
    • Garcia Silva MR, Tosar JP, Frugier M, Pantano S, Bonilla B, Esteban L, et al. Cloning, characterization and subcellular localization of a Trypanosoma cruzi argonaute protein defining a new subfamily distinctive of trypanosomatids. Gene. 2010;466:26-35.
    • (2010) Gene , vol.466 , pp. 26-35
    • Garcia Silva, M.R.1    Tosar, J.P.2    Frugier, M.3    Pantano, S.4    Bonilla, B.5    Esteban, L.6
  • 58
    • 84888329506 scopus 로고    scopus 로고
    • Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing
    • Jenjaroenpun P, Kremenska Y, Nair VM, Kremenskoy M, Joseph B, Kurochkin IV. Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing. Peer J. 2013;1:e201.
    • (2013) Peer J , vol.1 , pp. e201
    • Jenjaroenpun, P.1    Kremenska, Y.2    Nair, V.M.3    Kremenskoy, M.4    Joseph, B.5    Kurochkin, I.V.6
  • 59
    • 84864913576 scopus 로고    scopus 로고
    • Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs
    • Li Z, Ender C, Meister G, Moore PS, Chang Y, John B. Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs. Nucleic Acids Res. 2012;40:6787-99.
    • (2012) Nucleic Acids Res , vol.40 , pp. 6787-6799
    • Li, Z.1    Ender, C.2    Meister, G.3    Moore, P.S.4    Chang, Y.5    John, B.6
  • 60
    • 84885576702 scopus 로고    scopus 로고
    • Fungal small RNAs suppress plant immunity by hijacking host RNA interference pathways
    • Weiberg A, Wang M, Lin FM, Zhao H, Zhang Z, Kaloshian I, et al. Fungal small RNAs suppress plant immunity by hijacking host RNA interference pathways. Science. 2013;342:118-23.
    • (2013) Science , vol.342 , pp. 118-123
    • Weiberg, A.1    Wang, M.2    Lin, F.M.3    Zhao, H.4    Zhang, Z.5    Kaloshian, I.6
  • 61
    • 84900022563 scopus 로고    scopus 로고
    • Gene expression changes induced by Trypanosoma cruzi shed microvesicles in mammalian host cells: relevance of tRNA-derived halves
    • Garcia-Silva MR, Cabrera-Cabrera F, das Neves RF, Souto-Padron T, de Souza W, Cayota A. Gene expression changes induced by Trypanosoma cruzi shed microvesicles in mammalian host cells: relevance of tRNA-derived halves. Biomed Res Int. 2014;2014:305239.
    • (2014) Biomed Res Int , vol.2014 , pp. 305239
    • Garcia-Silva, M.R.1    Cabrera-Cabrera, F.2    das Neves, R.F.3    Souto-Padron, T.4    de Souza, W.5    Cayota, A.6
  • 62
    • 84906213108 scopus 로고    scopus 로고
    • tRNAs as regulators of biological processes
    • Raina M, Ibba M. tRNAs as regulators of biological processes. Front Genet. 2014;5:171.
    • (2014) Front Genet , vol.5 , pp. 171
    • Raina, M.1    Ibba, M.2
  • 63
    • 84921448966 scopus 로고    scopus 로고
    • Meta-analysis of tRNA derived RNA fragments reveals that they are evolutionarily conserved and associate with AGO proteins to recognize specific RNA targets
    • Kumar P, Anaya J, Mudunuri SB, Dutta A. Meta-analysis of tRNA derived RNA fragments reveals that they are evolutionarily conserved and associate with AGO proteins to recognize specific RNA targets. BMC Biol. 2014;12:78.
    • (2014) BMC Biol , vol.12 , pp. 78
    • Kumar, P.1    Anaya, J.2    Mudunuri, S.B.3    Dutta, A.4
  • 64
    • 80051713296 scopus 로고    scopus 로고
    • Angiogenin-induced tRNA fragments inhibit translation initiation
    • Ivanov P, Emara MM, Villen J, Gygi SP, Anderson P. Angiogenin-induced tRNA fragments inhibit translation initiation. Mol Cell. 2011;43:613-23.
    • (2011) Mol Cell , vol.43 , pp. 613-623
    • Ivanov, P.1    Emara, M.M.2    Villen, J.3    Gygi, S.P.4    Anderson, P.5
  • 65
    • 84872784032 scopus 로고    scopus 로고
    • tRNA-derived fragments target the ribosome and function as regulatory non-coding RNA in Haloferax volcanii
    • Gebetsberger J, Zywicki M, Kunzi A, Polacek N. tRNA-derived fragments target the ribosome and function as regulatory non-coding RNA in Haloferax volcanii. Archaea. 2012;2012:260909.
    • (2012) Archaea , vol.2012 , pp. 260909
    • Gebetsberger, J.1    Zywicki, M.2    Kunzi, A.3    Polacek, N.4
  • 66
    • 84879025267 scopus 로고    scopus 로고
    • Small RNAs derived from the 5' end of tRNA can inhibit protein translation in human cells
    • Sobala A, Hutvagner G. Small RNAs derived from the 5' end of tRNA can inhibit protein translation in human cells. RNA Biol. 2013;10:553-63.
    • (2013) RNA Biol , vol.10 , pp. 553-563
    • Sobala, A.1    Hutvagner, G.2
  • 67
    • 84872870536 scopus 로고    scopus 로고
    • tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma
    • Maute RL, Schneider C, Sumazin P, Holmes A, Califano A, Basso K, et al. tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma. Proc Natl Acad Sci U S A. 2013;110:1404-9.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 1404-1409
    • Maute, R.L.1    Schneider, C.2    Sumazin, P.3    Holmes, A.4    Califano, A.5    Basso, K.6
  • 68
    • 84878112453 scopus 로고    scopus 로고
    • Evidence of tRNA cleavage in apicomplexan parasites: Half-tRNAs as new potential regulatory molecules of Toxoplasma gondii and Plasmodium berghei
    • Galizi R, Spano F, Giubilei MA, Capuccini B, Magini A, Urbanelli L, et al. Evidence of tRNA cleavage in apicomplexan parasites: Half-tRNAs as new potential regulatory molecules of Toxoplasma gondii and Plasmodium berghei. Mol Biochem Parasitol. 2013;188:99-108.
    • (2013) Mol Biochem Parasitol , vol.188 , pp. 99-108
    • Galizi, R.1    Spano, F.2    Giubilei, M.A.3    Capuccini, B.4    Magini, A.5    Urbanelli, L.6
  • 69
    • 84866978293 scopus 로고    scopus 로고
    • Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi
    • Reifur L, Garcia-Silva MR, Poubel SB, Alves LR, Arauco P, Buiar DK, et al. Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi. Mem Inst Oswaldo Cruz. 2012;107:816-9.
    • (2012) Mem Inst Oswaldo Cruz , vol.107 , pp. 816-819
    • Reifur, L.1    Garcia-Silva, M.R.2    Poubel, S.B.3    Alves, L.R.4    Arauco, P.5    Buiar, D.K.6
  • 70
    • 84893147804 scopus 로고    scopus 로고
    • Slicing tRNAs to boost functional ncRNA diversity
    • Gebetsberger J, Polacek N. Slicing tRNAs to boost functional ncRNA diversity. RNA Biol. 2013;10:1798-806.
    • (2013) RNA Biol , vol.10 , pp. 1798-1806
    • Gebetsberger, J.1    Polacek, N.2
  • 71
    • 26444540413 scopus 로고    scopus 로고
    • Extensive 3' modification of plant small RNAs is modulated by helper component-proteinase expression
    • Ebhardt HA, Thi EP, Wang MB, Unrau PJ. Extensive 3' modification of plant small RNAs is modulated by helper component-proteinase expression. Proc Natl Acad Sci U S A. 2005;102:13398-403.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 13398-13403
    • Ebhardt, H.A.1    Thi, E.P.2    Wang, M.B.3    Unrau, P.J.4
  • 72
    • 80054913451 scopus 로고    scopus 로고
    • FLASH: fast length adjustment of short reads to improve genome assemblies
    • Magoc T, Salzberg SL. FLASH: fast length adjustment of short reads to improve genome assemblies. Bioinformatics. 2011;27:2957-63.
    • (2011) Bioinformatics , vol.27 , pp. 2957-2963
    • Magoc, T.1    Salzberg, S.L.2
  • 73
    • 84859210032 scopus 로고    scopus 로고
    • Fast gapped-read alignment with Bowtie 2
    • Langmead B, Salzberg SL. Fast gapped-read alignment with Bowtie 2. Nat Methods. 2012;9:357-9.
    • (2012) Nat Methods , vol.9 , pp. 357-359
    • Langmead, B.1    Salzberg, S.L.2
  • 74
    • 84928987900 scopus 로고    scopus 로고
    • HTSeq - A Python framework to work with high-throughput sequencing data
    • Anders S, Pyl PT, Huber W. HTSeq - A Python framework to work with high-throughput sequencing data. Bioinformatics. 2015;31:166-9.
    • (2015) Bioinformatics , vol.31 , pp. 166-169
    • Anders, S.1    Pyl, P.T.2    Huber, W.3
  • 76
    • 80051941094 scopus 로고    scopus 로고
    • Identification of novel transcripts in annotated genomes using RNA-Seq
    • Roberts A, Pimentel H, Trapnell C, Pachter L. Identification of novel transcripts in annotated genomes using RNA-Seq. Bioinformatics. 2011;27:2325-9.
    • (2011) Bioinformatics , vol.27 , pp. 2325-2329
    • Roberts, A.1    Pimentel, H.2    Trapnell, C.3    Pachter, L.4
  • 77
    • 0034201441 scopus 로고    scopus 로고
    • EMBOSS: the European Molecular Biology Open Software Suite
    • Rice P, Longden I, Bleasby A. EMBOSS: the European Molecular Biology Open Software Suite. Trends Genet. 2000;16:276-7.
    • (2000) Trends Genet , vol.16 , pp. 276-277
    • Rice, P.1    Longden, I.2    Bleasby, A.3
  • 80
    • 0040506228 scopus 로고    scopus 로고
    • A Laboratory guide to RNA: isolation, analysis, and synthesis
    • New York, NY: Wiley-Liss Inc.
    • Krieg P. A Laboratory guide to RNA: isolation, analysis, and synthesis. New York, NY: Wiley-Liss Inc.; 1996.
    • (1996)
    • Krieg, P.1
  • 81
    • 81455155120 scopus 로고    scopus 로고
    • In situ hybridisation for the detection of Leishmania species in paraffin wax-embedded canine tissues using a digoxigenin-labelled oligonucleotide probe
    • Dinhopl N, Mostegl MM, Richter B, Nedorost N, Maderner A, Fragner K, et al. In situ hybridisation for the detection of Leishmania species in paraffin wax-embedded canine tissues using a digoxigenin-labelled oligonucleotide probe. Vet Rec. 2011;169:525.
    • (2011) Vet Rec , vol.169 , pp. 525
    • Dinhopl, N.1    Mostegl, M.M.2    Richter, B.3    Nedorost, N.4    Maderner, A.5    Fragner, K.6
  • 82
    • 0003529272 scopus 로고
    • Methods in yeast genetics: a laboratory course manual
    • NY: Cold Spring Harbor Laboratory Press, Cold Spring Harbor
    • Rose M, Winston F, Hieter P. Methods in yeast genetics: a laboratory course manual. NY: Cold Spring Harbor Laboratory Press, Cold Spring Harbor, 1990.
    • (1990)
    • Rose, M.1    Winston, F.2    Hieter, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.