Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi

Memorias do Instituto Oswaldo Cruz

Volumn 107, Issue 6, 2012, Pages 816-819

  Reifur, Larissa ^a,c   Garcia Silva, Maria Rosa ^b   Poubel, Saloê Bispo ^a   Alves, Lysangela Ronalte ^a   Arauco, Paulo ^a   Buiar, Diane Kelly ^c   Goldenberg, Samuel ^a   Cayota, Alfonso ^b   Dallagiovanna, Bruno ^a  

^a INSTITUTO CARLOS CHAGAS   (Brazil)

^b INSTITUT PASTEUR DE MONTEVIDEO   (Uruguay)

^c FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

Author keywords

Derived fragments; Subcellular localization; tRNA; Trypanosoma cruzi

Indexed keywords

PROTOZOAL RNA; TRANSFER RNA;

ARTICLE; CELL GRANULE; CHEMISTRY; GENETICS; TRYPANOSOMA CRUZI;

CYTOPLASMIC GRANULES; RNA, PROTOZOAN; RNA, TRANSFER; TRYPANOSOMA CRUZI;

EUKARYOTA; PROKARYOTA; TRYPANOSOMA CRUZI;

EID: 84866978293     PISSN: 00740276     EISSN: 16788060     Source Type: Journal    
DOI: 10.1590/S0074-02762012000600018     Document Type: Article

References (21)

1. Bernhart SH, Hofacker IL, Will S, Gruber AR, Stadler PF 2008. RNAalifold: improved consensus structure prediction for RNA alignments. BMC Bioinformatics 9: 474.
2. Contreras VT, Salles JM, Thomas N, Morel CM, Goldenberg S 1985. In vitro differentiation of Trypanosoma cruzi under chemically defined conditions. Mol Biochem Parasitol 16: 315-327.
3. Dallagiovanna B, Perez L, Sotelo-Silveira J, Smircich P, Duhagon MA, Garat B 2005. Trypanosoma cruzi: molecular characterization of TcPUF6, a Pumilio protein. Exp Parasitol 109: 260-264.
4. Dumas C, Chow C, Muller M, Papadopoulou B 2006. A novel class of developmentally regulated noncoding RNAs in Leishmania. Eukaryot Cell 5: 2033-2046.
5. Elbarbary RA, Takaku H, Uchiumi N, Tamiya H, Abe M, Takahashi M, Nishida H, Nashimoto M 2009. Modulation of gene expression by human cytosolic tRNase Z(L) through 5'-half-tRNA. PLoS ONE 4: e5908.
6. Ferreira LR, Dossin F de M, Ramos TC, Freymuller E, Schenkman S 2008. Active transcription and ultrastructural changes during Trypanosoma cruzi metacyclogenesis. An Acad Bras Cienc 80: 157-166.
7. Figueiredo RC, Rosa DS, Soares MJ 2000. Differentiation of Trypanosoma cruzi epimastigotes: metacyclogenesis and adhesion to substrate are triggered by nutritional stress. J Parasitol 86: 1213-1218.
8. Franzén O, Arner E, Ferella M, Nilsson D, Respuela P, Carninci P, Hayashizaki Y, Aslund L, Andersson B, Daub CO 2011. The short non-coding transcriptome of the protozoan parasite Trypanosoma cruzi. PLoS Negl Trop Dis 5: e1283.
9. Garcia-Silva MR, Frugier M, Tosar JP, Correa-Dominguez A, Ronal-te-Alves L, Parodi-Talice A, Rovira C, Robello C, Goldenberg S, Cayota A 2010. A population of tRNA-derived small RNAs is actively produced in Trypanosoma cruzi and recruited to specific cytoplasmic granules. Mol Biochem Parasitol 171: 64-73.
10. Haile S, Papadopoulou B 2007. Developmental regulation of gene expression in trypanosomatid parasitic protozoa. Curr Opin Microbiol 10: 569-577.
11. Haussecker D, Huang Y, Lau A, Parameswaran P, Fire AZ, Kay MA, 2010. Human tRNA-derived small RNAs in the global regulation of RNA silencing. RNA 16: 673-695.
12. Horn D 2008. Codon usage suggests that translational selection has a major impact on protein expression in trypanosomatids. BMC Genomics 9: 2.
13. Lee SR, Collins K 2005. Starvation-induced cleavage of the tRNA anticodon loop in Tetrahymena thermophila. J Biol Chem 280: 42744-42749.
14. Li Y, Luo J, Zhou H, Liao JY, Ma LM, Chen YQ, Qu LH 2008. Stress-induced tRNA-derived RNAs: a novel class of small RNAs in the primitive eukaryote Giardia lamblia. Nucleic Acids Res 36: 6048-6055.
15. Michaeli S, Doniger T, Gupta SK, Wurtzel O, Romano M, Visnovezky D, Sorek R, Unger R, Ullu E 2012. RNA-seq analysis of small RNPs in Trypanosoma brucei reveals a rich repertoire of non-coding RNAs. Nucleic Acids Res 40: 1282-1298.
16. Minning TA, Weatherly DB, Atwood J 3rd, Orlando R, Tarleton RL 2009. The steady-state transcriptome of the four major life-cycle stages of Trypanosoma cruzi. BMC Genomics 10: 370.
17. Nardelli SC, Avila AR, Freund A, Motta MC, Manhaes L, de Jesus TC, Schenkman S, Fragoso SP, Krieger MA, Goldenberg S, Dallagiovanna B 2007. Small-subunit rRNA processome proteins are translationally regulated during differentiation of Trypanosoma cruzi. Eukaryot Cell 6: 337-345.
18. Padilla-Mejia NE, Florencio-Martinez LE, Figueroa-Angulo EE, Manning-Cela RG, Hernandez-Rivas R, Myler PJ, Martinez-Calvillo S 2009. Gene organization and sequence analyses of transfer RNA genes in trypanosomatid parasites. BMC Genomics 10: 232.
19. Pederson T 2010. Regulatory RNAs derived from transfer RNA? RNA 16: 1865-1869.
20. Pucadyil TJ, Schmid SL 2009. Conserved functions of membrane active GTPases in coated vesicle formation. Science 325: 1217-1220.
21. Will S, Reiche K, Hofacker IL, Stadler PF, Backofen R 2007. Inferring noncoding RNA families and classes by means of genome-scale structure-based clustering. PLoS Comput Biol 3: 680-691.