Characterization of the small RNA content of Trypanosoma cruzi extracellular vesicles

Molecular and Biochemical Parasitology

Volumn 193, Issue 2, 2014, Pages 71-74

  Bayer Santos, Ethel ^a,b   Lima, Fábio Mitsuo ^a   Ruiz, Jeronimo Conceição ^c   Almeida, Igor C ^b   Da Silveira, José Franco ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF TEXAS AT EL PASO   (United States)

^c INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

Comparative transcriptome; Extracellular vesicles; High throughput data analysis; Small noncoding RNA; Trypanosoma cruzi

Indexed keywords

ARTICLE; CELL COMMUNICATION; CELL VACUOLE; DNA LIBRARY; EPIMASTIGOTE; EXTRACELLULAR VESICLE; GENE EXPRESSION REGULATION; GENE SILENCING; HETEROCHROMATIN; HOMOLOGOUS RECOMBINATION; HOST CELL; HOST PATHOGEN INTERACTION; MAMMAL CELL; MEMBRANE VESICLE; MULTIGENE FAMILY; MULTIVESICULAR BODY; NONHUMAN; OXIDATIVE STRESS; PARASITE VIABILITY; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN SYNTHESIS; PSEUDOGENE; RETROPOSON; RNA ANALYSIS; RNA DEGRADATION; RNA METABOLISM; RNA PROCESSING; RNA SEQUENCE; RNA STABILITY; RNA TRANSLATION; TRANSCRIPTION REGULATION; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI; TRYPOMASTIGOTE; EXTRACELLULAR SPACE; GENE LIBRARY; GENETICS; HIGH THROUGHPUT SEQUENCING; TRANSPORT VESICLE;

MAMMALIA; TRYPANOSOMA CRUZI;

PROTOZOAL RNA; TRANSFER RNA;

EXTRACELLULAR SPACE; GENE LIBRARY; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; RNA, PROTOZOAN; RNA, TRANSFER; TRANSPORT VESICLES; TRYPANOSOMA CRUZI;

EID: 84895917022     PISSN: 01666851     EISSN: 18729428     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2014.02.004     Document Type: Article

References (22)

1. M. Belting, and A. Wittrup Nanotubes, exosomes, and nucleic acid-binding peptides provide novel mechanisms of intercellular communication in eukaryotic cells: implications in health and disease J Cell Biol 183 7 2008 1187 1191
2. E. Cocucci, G. Racchetti, and J. Meldolesi Shedding microvesicles: artefacts no more Trends Cell Biol 19 2 2009 43 51
3. B. Gyorgy, T.G. Szabo, M. Pasztoi, Z. Pal, P. Misjak, and B. Aradi et al. Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles Cell Mol Life Sci 68 16 2011 2667 2688
4. E. Bayer-Santos, C. Aguilar-Bonavides, S.P. Rodrigues, E.M. Cordero, A.F. Marques, and A. Varela-Ramirez et al. Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins J Proteome Res 12 2 2013 883 897
5. H. Valadi, K. Ekstrom, A. Bossios, M. Sjostrand, J.J. Lee, and J.O. Lotvall Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells Nat Cell Biol 9 6 2007 654 659 (Pubitemid 47214727)
6. Z. Li, C. Ender, G. Meister, P.S. Moore, Y. Chang, and B. John Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs Nucleic Acids Res 40 14 2012 6787 6799
7. H.P. Cam, T. Sugiyama, E.S. Chen, X. Chen, P.C. FitzGerald, and S.I. Grewal Comprehensive analysis of heterochromatin- and RNAi-mediated epigenetic control of the fission yeast genome Nat Genet 37 8 2005 809 819 (Pubitemid 41077106)
8. O. Franzen, E. Arner, M. Ferella, D. Nilsson, P. Respuela, and P. Carninci et al. The short non-coding transcriptome of the protozoan parasite Trypanosoma cruzi PLoS Negl Trop Dis 5 8 2011 e1283
9. M.R. Garcia-Silva, M. Frugier, J.P. Tosar, A. Correa-Dominguez, L. Ronalte-Alves, and A. Parodi-Talice et al. A population of tRNA-derived small RNAs is actively produced in Trypanosoma cruzi and recruited to specific cytoplasmic granules Mol Biochem Parasitol 171 2 2010 64 73
10. L. Reifur, M.R. Garcia-Silva, S.B. Poubel, L.R. Alves, P. Arauco, and D.K. Buiar et al. Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi Mem Inst Oswaldo Cruz 107 6 2012 816 819
11. L.L. Zheng, Y.Z. Wen, J.H. Yang, J.Y. Liao, P. Shao, and H. Xu et al. Comparative transcriptome analysis of small noncoding RNAs in different stages of Trypanosoma brucei RNA 19 7 2013 863 875
12. E. Ullu, C. Tschudi, and T. Chakraborty RNA interference in protozoan parasites Cell Microbiol 6 6 2004 509 519 (Pubitemid 38618662)
13. Y. Kawamura, K. Saito, T. Kin, Y. Ono, K. Asai, and T. Sunohara et al. Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells Nature 453 7196 2008 793 797 (Pubitemid 351793781)
14. D. Haussecker, Y. Huang, A. Lau, P. Parameswaran, A.Z. Fire, and M.A. Kay Human tRNA-derived small RNAs in the global regulation of RNA silencing RNA 16 4 2010 673 695
15. J.G. De Gaudenzi, G. Noe, V.A. Campo, A.C. Frasch, and A. Cassola Gene expression regulation in trypanosomatids Essays Biochem 51 2011 31 46
16. R.A. Elbarbary, H. Takaku, N. Uchiumi, H. Tamiya, M. Abe, and M. Takahashi et al. Modulation of gene expression by human cytosolic tRNase Z(L) through 5′-half-tRNA PLoS One 4 6 2009 e5908
17. A. Nakashima, H. Takaku, H.S. Shibata, Y. Negishi, M. Takagi, and M. Tamura et al. Gene silencing by the tRNA maturase tRNase ZL under the direction of small-guide RNA Gene Ther 14 1 2007 78 85 (Pubitemid 44942868)
18. Y.Z. Wen, L.L. Zheng, J.Y. Liao, M.H. Wang, Y. Wei, and X.M. Guo et al. Pseudogene-derived small interference RNAs regulate gene expression in African Trypanosoma brucei Proc Natl Acad Sci USA 108 20 2011 8345 8350
19. X. Chen, H. Liang, J. Zhang, K. Zen, and C.Y. Zhang Horizontal transfer of microRNAs: molecular mechanisms and clinical applications Protein Cell 3 1 2012 28 37
20. N. Regev-Rudzki, D.W. Wilson, T.G. Carvalho, X. Sisquella, B.M. Coleman, and M. Rug et al. Cell-cell communication between malaria-infected red blood cells via exosome-like vesicles Cell 153 5 2013 1120 1133
21. M.R. Garcia-Silva, R.F. Cura das Neves, F. Cabrera-Cabrera, J. Sanguinetti, L.C. Medeiros, and C. Robello et al. Extracellular vesicles shed by Trypanosoma cruzi are linked to small RNA pathways, life cycle regulation, and susceptibility to infection of mammalian cells Parasitol Res 113 (1), 2013, 285-304
22. M.M. Hecht, N. Nitz, P.F. Araujo, A.O. Sousa, C. Rosa Ade, and D.A. Gomes et al. Inheritance of DNA transferred from American trypanosomes to human hosts PLoS One 5 2 2010 e9181