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Volumn 18, Issue 5, 2015, Pages 666-673

A coding-independent function of an alternative Ube3a transcript during neuronal development

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; UBE3A PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; ISOPROTEIN; MESSENGER RNA; NERVE PROTEIN; SMALL INTERFERING RNA; UBE3A PROTEIN, RAT; UBIQUITIN PROTEIN LIGASE;

EID: 84928699039     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.3996     Document Type: Article
Times cited : (84)

References (49)
  • 1
    • 84872593582 scopus 로고    scopus 로고
    • Activity-dependent neuronal signalling and autism spectrum disorder
    • Ebert, D.H. & Greenberg, M.E. Activity-dependent neuronal signalling and autism spectrum disorder. Nature 493, 327-337 (2013).
    • (2013) Nature , vol.493 , pp. 327-337
    • Ebert, D.H.1    Greenberg, M.E.2
  • 2
    • 0032192481 scopus 로고    scopus 로고
    • Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and defcits of contextual learning and long-term potentiation
    • Jiang, Y.H. et al. Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and defcits of contextual learning and long-term potentiation. Neuron 21, 799-811 (1998).
    • (1998) Neuron , vol.21 , pp. 799-811
    • Jiang, Y.H.1
  • 3
    • 0031031570 scopus 로고    scopus 로고
    • De novo truncating mutations in E6-AP ubiquitin-protein ligase gene (UBE3A) in Angelman syndrome
    • Matsuura, T. et al. De novo truncating mutations in E6-AP ubiquitin-protein ligase gene (UBE3A) in Angelman syndrome. Nat. Genet. 15, 74-77 (1997).
    • (1997) Nat. Genet. , vol.15 , pp. 74-77
    • Matsuura, T.1
  • 4
    • 67349182343 scopus 로고    scopus 로고
    • Autism genome-wide copy number variation reveals ubiquitin and neuronal genes
    • Glessner, J.T. et al. Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. Nature 459, 569-573 (2009).
    • (2009) Nature , vol.459 , pp. 569-573
    • Glessner, J.T.1
  • 5
    • 77950386683 scopus 로고    scopus 로고
    • Genomic imprinting of experience-dependent cortical plasticity by the ubiquitin ligase gene Ube3a
    • Sato, M. & Stryker, M.P. Genomic imprinting of experience-dependent cortical plasticity by the ubiquitin ligase gene Ube3a. Proc. Natl. Acad. Sci. USA 107, 5611-5616 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 5611-5616
    • Sato, M.1    Stryker, M.P.2
  • 6
    • 67349178189 scopus 로고    scopus 로고
    • Ube3a is required for experience-dependent maturation of the neocortex
    • Yashiro, K. et al. Ube3a is required for experience-dependent maturation of the neocortex. Nat. Neurosci. 12, 777-783 (2009).
    • (2009) Nat. Neurosci. , vol.12 , pp. 777-783
    • Yashiro, K.1
  • 7
    • 84861950914 scopus 로고    scopus 로고
    • Maternal loss of Ube3a produces an excitatory/inhibitory imbalance through neuron type-specifc synaptic defects
    • Wallace, M.L., Burette, A.C., Weinberg, R.J. & Philpot, B.D. Maternal loss of Ube3a produces an excitatory/inhibitory imbalance through neuron type-specifc synaptic defects. Neuron 74, 793-800 (2012).
    • (2012) Neuron , vol.74 , pp. 793-800
    • Wallace, M.L.1    Burette, A.C.2    Weinberg, R.J.3    Philpot, B.D.4
  • 8
    • 37549057995 scopus 로고    scopus 로고
    • The Angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal defciency results in abnormal dendritic spine morphology
    • Dindot, S.V., Antalffy, B.A., Bhattacharjee, M.B. & Beaudet, A.L. The Angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal defciency results in abnormal dendritic spine morphology. Hum. Mol. Genet. 17, 111-118 (2008).
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 111-118
    • Dindot, S.V.1    Antalffy, B.A.2    Bhattacharjee, M.B.3    Beaudet, A.L.4
  • 9
    • 84871783676 scopus 로고    scopus 로고
    • The Angelman syndrome protein Ube3a is required for polarized dendrite morphogenesis in pyramidal neurons
    • Miao, S. et al. The Angelman syndrome protein Ube3a is required for polarized dendrite morphogenesis in pyramidal neurons. J. Neurosci. 33, 327-333 (2013).
    • (2013) J. Neurosci. , vol.33 , pp. 327-333
    • Miao, S.1
  • 10
    • 77649083119 scopus 로고    scopus 로고
    • The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc
    • Greer, P.L. et al. The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc. Cell 140, 704-716 (2010).
    • (2010) Cell , vol.140 , pp. 704-716
    • Greer, P.L.1
  • 11
    • 77958487953 scopus 로고    scopus 로고
    • EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation
    • Margolis, S.S. et al. EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation. Cell 143, 442-455 (2010).
    • (2010) Cell , vol.143 , pp. 442-455
    • Margolis, S.S.1
  • 12
    • 38349169664 scopus 로고    scopus 로고
    • Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight?
    • Filipowicz, W., Bhattacharyya, S.N. & Sonenberg, N. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat. Rev. Genet. 9, 102-114 (2008).
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 102-114
    • Filipowicz, W.1    Bhattacharyya, S.N.2    Sonenberg, N.3
  • 13
    • 70450248489 scopus 로고    scopus 로고
    • MicroRNAs at the synapse
    • Schratt, G. microRNAs at the synapse. Nat. Rev. Neurosci. 10, 842-849 (2009).
    • (2009) Nat. Rev. Neurosci. , vol.10 , pp. 842-849
    • Schratt, G.1
  • 14
    • 84864934256 scopus 로고    scopus 로고
    • MicroRNAs shape the neuronal landscape
    • McNeill, E. & Van Vactor, D. MicroRNAs shape the neuronal landscape. Neuron 75, 363-379 (2012).
    • (2012) Neuron , vol.75 , pp. 363-379
    • McNeill, E.1    Van Vactor, D.2
  • 15
    • 4644253753 scopus 로고    scopus 로고
    • A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain
    • Seitz, H. et al. A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain. Genome Res. 14, 1741-1748 (2004).
    • (2004) Genome Res. , vol.14 , pp. 1741-1748
    • Seitz, H.1
  • 16
    • 62649086993 scopus 로고    scopus 로고
    • Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fne-tuning Pumilio2 protein levels
    • Fiore, R. et al. Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fne-tuning Pumilio2 protein levels. EMBO J. 28, 697-710 (2009).
    • (2009) EMBO J. , vol.28 , pp. 697-710
    • Fiore, R.1
  • 17
    • 31144479591 scopus 로고    scopus 로고
    • A brain-specifc microRNA regulates dendritic spine development
    • Schratt, G.M. et al. A brain-specifc microRNA regulates dendritic spine development. Nature 439, 283-289 (2006).
    • (2006) Nature , vol.439 , pp. 283-289
    • Schratt, G.M.1
  • 18
    • 77956185062 scopus 로고    scopus 로고
    • A novel pathway regulates memory and plasticity via SIRT1 and miR-134
    • Gao, J. et al. A novel pathway regulates memory and plasticity via SIRT1 and miR-134. Nature 466, 1105-1109 (2010).
    • (2010) Nature , vol.466 , pp. 1105-1109
    • Gao, J.1
  • 19
    • 84863715734 scopus 로고    scopus 로고
    • Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects
    • Jimenez-Mateos, E.M. et al. Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects. Nat. Med. 18, 1087-1094 (2012).
    • (2012) Nat. Med. , vol.18 , pp. 1087-1094
    • Jimenez-Mateos, E.M.1
  • 20
    • 84877308887 scopus 로고    scopus 로고
    • The DEAH-box helicase DHX36 mediates dendritic localization of the neuronal precursor-microRNA-134
    • Bicker, S. et al. The DEAH-box helicase DHX36 mediates dendritic localization of the neuronal precursor-microRNA-134. Genes Dev. 27, 991-996 (2013).
    • (2013) Genes Dev. , vol.27 , pp. 991-996
    • Bicker, S.1
  • 21
    • 0028907874 scopus 로고
    • A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase
    • Huibregtse, J.M., Scheffner, M., Beaudenon, S. & Howley, P.M. A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc. Natl. Acad. Sci. USA 92, 2563-2567 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2563-2567
    • Huibregtse, J.M.1    Scheffner, M.2    Beaudenon, S.3    Howley, P.M.4
  • 22
    • 0031569842 scopus 로고    scopus 로고
    • The human E6-AP gene (UBE3A) encodes three potential protein isoforms generated by differential splicing
    • Yamamoto, Y., Huibregtse, J.M. & Howley, P.M. The human E6-AP gene (UBE3A) encodes three potential protein isoforms generated by differential splicing. Genomics 41, 263-266 (1997).
    • (1997) Genomics , vol.41 , pp. 263-266
    • Yamamoto, Y.1    Huibregtse, J.M.2    Howley, P.M.3
  • 23
    • 4644295494 scopus 로고    scopus 로고
    • Biochemical analysis of Angelman syndrome-associated mutations in the E3 ubiquitin ligase E6-associated protein
    • Cooper, E.M., Hudson, A.W., Amos, J., Wagstaff, J. & Howley, P.M. Biochemical analysis of Angelman syndrome-associated mutations in the E3 ubiquitin ligase E6-associated protein. J. Biol. Chem. 279, 41208-41217 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 41208-41217
    • Cooper, E.M.1    Hudson, A.W.2    Amos, J.3    Wagstaff, J.4    Howley, P.M.5
  • 24
    • 3042821931 scopus 로고    scopus 로고
    • Regulation of the large (approximately 1000 kb) imprinted murine Ube3a antisense transcript by alternative exons upstream of Snurf/Snrpn
    • Landers, M. et al. Regulation of the large (approximately 1000 kb) imprinted murine Ube3a antisense transcript by alternative exons upstream of Snurf/Snrpn. Nucleic Acids Res. 32, 3480-3492 (2004).
    • (2004) Nucleic Acids Res. , vol.32 , pp. 3480-3492
    • Landers, M.1
  • 25
    • 84894246145 scopus 로고    scopus 로고
    • Activity-dependent changes in MAPK activation in the Angelman Syndrome mouse model
    • Filonova, I., Trotter, J.H., Banko, J.L. & Weeber, E.J. Activity-dependent changes in MAPK activation in the Angelman Syndrome mouse model. Learn. Mem. 21, 98-104 (2014).
    • (2014) Learn. Mem. , vol.21 , pp. 98-104
    • Filonova, I.1    Trotter, J.H.2    Banko, J.L.3    Weeber, E.J.4
  • 26
    • 60149086205 scopus 로고    scopus 로고
    • MRNA localization: Gene expression in the spatial dimension
    • Martin, K.C. & Ephrussi, A. mRNA localization: gene expression in the spatial dimension. Cell 136, 719-730 (2009).
    • (2009) Cell , vol.136 , pp. 719-730
    • Martin, K.C.1    Ephrussi, A.2
  • 27
    • 0032191909 scopus 로고    scopus 로고
    • Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites
    • Steward, O., Wallace, C.S., Lyford, G.L. & Worley, P.F. Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites. Neuron 21, 741-751 (1998).
    • (1998) Neuron , vol.21 , pp. 741-751
    • Steward, O.1    Wallace, C.S.2    Lyford, G.L.3    Worley, P.F.4
  • 28
    • 9144225636 scopus 로고    scopus 로고
    • The Microprocessor complex mediates the genesis of microRNAs
    • Gregory, R.I. et al. The Microprocessor complex mediates the genesis of microRNAs. Nature 432, 235-240 (2004).
    • (2004) Nature , vol.432 , pp. 235-240
    • Gregory, R.I.1
  • 29
    • 28444495985 scopus 로고    scopus 로고
    • Identifcation of novel argonaute-associated proteins
    • Meister, G. et al. Identifcation of novel argonaute-associated proteins. Curr. Biol. 15, 2149-2155 (2005).
    • (2005) Curr. Biol. , vol.15 , pp. 2149-2155
    • Meister, G.1
  • 30
    • 84892573723 scopus 로고    scopus 로고
    • The multilayered complexity of ceRNA crosstalk and competition
    • Tay, Y., Rinn, J. & Pandolf, P.P. The multilayered complexity of ceRNA crosstalk and competition. Nature 505, 344-352 (2014).
    • (2014) Nature , vol.505 , pp. 344-352
    • Tay, Y.1    Rinn, J.2    Pandolf, P.P.3
  • 31
    • 45849149279 scopus 로고    scopus 로고
    • Behavioural and neurochemical effects of post-weaning social isolation in rodents-relevance to developmental neuropsychiatric disorders
    • Fone, K.C. & Porkess, M.V. Behavioural and neurochemical effects of post-weaning social isolation in rodents-relevance to developmental neuropsychiatric disorders. Neurosci. Biobehav. Rev. 32, 1087-1102 (2008).
    • (2008) Neurosci. Biobehav. Rev. , vol.32 , pp. 1087-1102
    • Fone, K.C.1    Porkess, M.V.2
  • 32
    • 80054700538 scopus 로고    scopus 로고
    • Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs
    • Tay, Y. et al. Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs. Cell 147, 344-357 (2011).
    • (2011) Cell , vol.147 , pp. 344-357
    • Tay, Y.1
  • 33
    • 84901838697 scopus 로고    scopus 로고
    • Assessing the ceRNA Hypothesis with Quantitative Measurements of miRNA and Target Abundance
    • Denzler, R., Agarwal, V., Stefano, J., Bartel, D.P. & Stoffel, M. Assessing the ceRNA Hypothesis with Quantitative Measurements of miRNA and Target Abundance. Mol. Cell 54, 766-776 (2014).
    • (2014) Mol. Cell , vol.54 , pp. 766-776
    • Denzler, R.1    Agarwal, V.2    Stefano, J.3    Bartel, D.P.4    Stoffel, M.5
  • 34
    • 84922418997 scopus 로고    scopus 로고
    • Endogenous miRNA and target concentrations determine susceptibility to potential ceRNA competition
    • Bosson, A.D., Zamudio, J.R. & Sharp, P.A. Endogenous miRNA and target concentrations determine susceptibility to potential ceRNA competition. Mol. Cell 56, 347-359 (2014).
    • (2014) Mol. Cell , vol.56 , pp. 347-359
    • Bosson, A.D.1    Zamudio, J.R.2    Sharp, P.A.3
  • 35
    • 9444279010 scopus 로고    scopus 로고
    • Depletion of MAP2 expression and laminar cytoarchitectonic changes in dorsolateral prefrontal cortex in adult autistic individuals
    • Mukaetova-Ladinska, E.B., Arnold, H., Jaros, E., Perry, R. & Perry, E. Depletion of MAP2 expression and laminar cytoarchitectonic changes in dorsolateral prefrontal cortex in adult autistic individuals. Neuropathol. Appl. Neurobiol. 30, 615-623 (2004).
    • (2004) Neuropathol. Appl. Neurobiol. , vol.30 , pp. 615-623
    • Mukaetova-Ladinska, E.B.1    Arnold, H.2    Jaros, E.3    Perry, R.4    Perry, E.5
  • 38
    • 72049108920 scopus 로고    scopus 로고
    • Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders
    • Hutsler, J.J. & Zhang, H. Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders. Brain Res. 1309, 83-94 (2010).
    • (2010) Brain Res. , vol.1309 , pp. 83-94
    • Hutsler, J.J.1    Zhang, H.2
  • 39
    • 79958074870 scopus 로고    scopus 로고
    • Multiple recurrent de novo CNVs including duplications of the 7q11.23 Williams syndrome region are strongly associated with autism
    • Sanders, S.J. et al. Multiple recurrent de novo CNVs, including duplications of the 7q11.23 Williams syndrome region, are strongly associated with autism. Neuron 70, 863-885 (2011).
    • (2011) Neuron , vol.70 , pp. 863-885
    • Sanders, S.J.1
  • 40
    • 34347215149 scopus 로고    scopus 로고
    • Object recognition in rats and mice: A one-trial non-matching-to-sample learning task to study 'recognition memory'
    • Bevins, R.A. & Besheer, J. Object recognition in rats and mice: a one-trial non-matching-to-sample learning task to study 'recognition memory'. Nat. Protoc. 1, 1306-1311 (2006).
    • (2006) Nat. Protoc. , vol.1 , pp. 1306-1311
    • Bevins, R.A.1    Besheer, J.2
  • 41
    • 33845807365 scopus 로고    scopus 로고
    • Identifcation of process-localized mRNAs from cultured rodent hippocampal neurons
    • Poon, M.M., Choi, S.H., Jamieson, C.A., Geschwind, D.H. & Martin, K.C. Identifcation of process-localized mRNAs from cultured rodent hippocampal neurons. J. Neurosci. 26, 13390-13399 (2006).
    • (2006) J. Neurosci. , vol.26 , pp. 13390-13399
    • Poon, M.M.1    Choi, S.H.2    Jamieson, C.A.3    Geschwind, D.H.4    Martin, K.C.5
  • 42
    • 77956147092 scopus 로고    scopus 로고
    • Recombinant adeno-associated virus-mediated microRNA delivery into the postnatal mouse brain reveals a role for miR-134 in dendritogenesis in vivo
    • Christensen, M., Larsen, L.A., Kauppinen, S. & Schratt, G. Recombinant adeno-associated virus-mediated microRNA delivery into the postnatal mouse brain reveals a role for miR-134 in dendritogenesis in vivo. Front. Neural Circuits 3, 16 (2010).
    • (2010) Front. Neural Circuits , vol.3 , pp. 16
    • Christensen, M.1    Larsen, L.A.2    Kauppinen, S.3    Schratt, G.4
  • 43
    • 12744255421 scopus 로고    scopus 로고
    • Promoters and serotypes: Targeting of adeno-associated virus vectors for gene transfer in the rat central nervous system in vitro and in vivo
    • Shevtsova, Z., Malik, J.M., Michel, U., Bahr, M. & Kugler, S. Promoters and serotypes: targeting of adeno-associated virus vectors for gene transfer in the rat central nervous system in vitro and in vivo. Exp. Physiol. 90, 53-59 (2005).
    • (2005) Exp. Physiol. , vol.90 , pp. 53-59
    • Shevtsova, Z.1    Malik, J.M.2    Michel, U.3    Bahr, M.4    Kugler, S.5
  • 44
    • 0033022953 scopus 로고    scopus 로고
    • Recombinant adeno-associated virus purifcation using novel methods improves infectious titer and yield
    • Zolotukhin, S. et al. Recombinant adeno-associated virus purifcation using novel methods improves infectious titer and yield. Gene Ther. 6, 973-985 (1999).
    • (1999) Gene Ther. , vol.6 , pp. 973-985
    • Zolotukhin, S.1
  • 45
    • 66949168048 scopus 로고    scopus 로고
    • A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis
    • Siegel, G. et al. A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis. Nat. Cell Biol. 11, 705-716 (2009).
    • (2009) Nat. Cell Biol. , vol.11 , pp. 705-716
    • Siegel, G.1
  • 46
    • 7244229656 scopus 로고    scopus 로고
    • BDNF regulates the translation of a select group of mRNAs by a mammalian target of rapamycin-phosphatidylinositol 3-kinase-dependent pathway during neuronal development
    • Schratt, G.M., Nigh, E.A., Chen, W.G., Hu, L. & Greenberg, M.E. BDNF regulates the translation of a select group of mRNAs by a mammalian target of rapamycin-phosphatidylinositol 3-kinase-dependent pathway during neuronal development. J. Neurosci. 24, 7366-7377 (2004).
    • (2004) J. Neurosci. , vol.24 , pp. 7366-7377
    • Schratt, G.M.1    Nigh, E.A.2    Chen, W.G.3    Hu, L.4    Greenberg, M.E.5
  • 47
    • 84871809302 scopus 로고    scopus 로고
    • STAR: Ultrafast universal RNA-seq aligner
    • Dobin, A. et al. STAR: ultrafast universal RNA-seq aligner. Bioinformatics 29, 15-21 (2013).
    • (2013) Bioinformatics , vol.29 , pp. 15-21
    • Dobin, A.1
  • 48
    • 68549104404 scopus 로고    scopus 로고
    • The Sequence Alignment/Map format and SAMtools
    • Li, H. et al. The Sequence Alignment/Map format and SAMtools. Bioinformatics 25, 2078-2079 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 2078-2079
    • Li, H.1
  • 49
    • 84875634162 scopus 로고    scopus 로고
    • Integrative Genomics Viewer (IGV): High-performance genomics data visualization and exploration
    • Thorvaldsdóttir, H., Robinson, J.T. & Mesirov, J.P. Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration. Brief. Bioinform. 14, 178-192 (2013).
    • (2013) Brief. Bioinform. , vol.14 , pp. 178-192
    • Thorvaldsdóttir, H.1    Robinson, J.T.2    Mesirov, J.P.3


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