Antioxidant effects of pineapple vinegar in reversing of paracetamol-induced liver damage in mice

Chinese Medicine (United Kingdom)

Volumn 10, Issue 1, 2015, Pages

  Mohamad, Nurul E ^a   Yeap, Swee Keong ^a   Lim, Kian Lim ^b   Yusof, Hamidah Mohd ^a   Beh, Boon Kee ^b   Tan, Sheau Wei ^a   Ho, Wan Yong ^c   Sharifuddin, Shaiful Adzni ^d   Jamaluddin, Anisah ^d   Long, Kamariah ^d   Nik Abd Rahman, Nik Mohd Afizan ^a   Alitheen, Noorjahan Banu ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

^b UNIVERSITI TUNKU ABDUL RAHMAN   (Malaysia)

^c UNIVERSITY OF NOTTINGHAM MALAYSIA CAMPUS   (Malaysia)

^d MALAYSIAN AGRICULTURAL RESEARCH AND DEVELOPMENT INSTITUTE MARDI   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CYTOCHROME P450 2E1; GALLIC ACID; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIVER PROTECTIVE AGENT; MALONALDEHYDE; NITRIC OXIDE; PARACETAMOL; PHENOL DERIVATIVE; PINEAPPLE VINEGAR; SILIBININ; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VINEGAR;

AEROBIC FERMENTATION; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANAEROBIC FERMENTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DRUG DOSE COMPARISON; GENE EXPRESSION; IC50; IN VITRO STUDY; LIPID PEROXIDATION; LIVER PROTECTION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; PINEAPPLE JUICE; PROTEIN EXPRESSION; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 84928672476     PISSN: None     EISSN: 17498546     Source Type: Journal    
DOI: 10.1186/s13020-015-0030-4     Document Type: Article

References (54)

1. Frayn KN, Arner P, Yki-Järvinen H. Fatty acid metabolism in adipose tissue, muscle and liver in health and disease. Essays Biochem 2006, 42:89-103. 10.1042/bse0420089, 17144882.
2. Miller LL, Bly CG, Watson ML, Bale WF. The dominant role of the liver in plasma protein synthesis,a direct study of the isolated perfused rat liver with the aid of lysine-ε{lunate}-C14. J Exp Med 1951, 94:431-53. 10.1084/jem.94.5.431, 14888824.
3. Farrar WE, Corwin LM. The essential role of the liver in detoxification of endotoxin. Ann N Y Acad Sci 1966, 133:668-84. 10.1111/j.1749-6632.1966.tb52397.x, 5336354.
4. Poli G. Liver damage due to free radicals. Oxford J Med 1993, 49:604-20.
5. Prescott LF. Paracetamol overdosage. Drugs 1983, 25:290-314. 10.2165/00003495-198325030-00002, 6343056.
6. Bhanwra S, Singh J, Khosla P. Effect ofAzadirachta indica(neem) leaf aqueous extracton paracetamol-induced liver damage in rats. Indian J Physiol Pharmacol 2000, 44:64-8. 10919097.
7. Bullon P, Newman HN, Battino M. Obesity, diabetes mellitus, atherosclerosis and chronic periodontitis: a shared pathology via oxidative stress and mitochondrial dysfunction?. Periodontology 2014, 64:139-53. 10.1111/j.1600-0757.2012.00455.x.
8. Pinsirodom P, Rungcharoen J, Liumminful A. Quality of commercial wine vinegars evaluated on the basis of total polyphenol content and antioxidant properties. Asian J Food Agro-Industry 2010, 3:389-97.
9. Seki T, Morimura S, Tabata S, Tang Y, Shigematsu T, Kida K. Antioxidant activity of vinegar produced from distilled residues of the japanese liquour shochu. J Agric Food Chem 2008, 56:3785-90. 10.1021/jf073040w, 18433134.
10. Guerrero EDA, Mej'i{dotless}as RC, Mar'i{dotless}n RN, Lovillo MP, Barroso CG. A new FT-IRmethod combined with multivariate analysis for the classification of vinegars from different raw materials and production processes. J Sci Food Agric 2010, 90:712-8. 20355103.
11. Budak NH, Doguc DK, M Savas C, Seydim AC, Tas TK, Ciris MI, et al. Effects of apple cider vinegars produced with different techniques on blood lipids in high-cholesterol-fed rats. J Agric Food Chem 2011, 59:6638-44. 10.1021/jf104912h, 21561165.
12. Gu X, Zhao H-L, Sui Y, Guan J, Chan JCN, Tong PCY. White rice vinegar improves pancreatic beta-cell function and fatty liver in streptozotocin-induced diabetic rats. Acta Diabetol 2012, 49:185-91. 10.1007/s00592-010-0184-6, 20514502.
13. Kondo S, Tayama K, Tsukamoto Y, Ikeda K, Yamori Y. Antihypertensive effects of acetic acid and vinegar on spontaneously hypertensive rats. Biosci Biotechnol Biochem 2001, 65:2690-4. 10.1271/bbb.65.2690, 11826965.
14. Shimoji Y, Kohno H, Nanda K, Nishikawa Y, Ohigashi H, Uenakai K, et al. Extract of kurosu, a vinegar from unpolished rice, inhibits azoxymethane-induced colon carcinogenesis in male F344 rats. Nutr Cancer 2004, 49:170-3. 10.1207/s15327914nc4902_8, 15489210.
15. Fan J, Zhang Y, Chang X, Zhang B, Jiang D, Saito M, et al. Antithrombotic and fibrinolytic activities of methanolic extract of aged sorghum vinegar. J Agric Food Chem 2009, 57:8683-7. 10.1021/jf901680y, 19754177.
16. Pinto TMS, Neves ACC, Leao MVP, Jorge AOC. Vinegar as antimicrobial agent for control ofCandida spp.in complete denture wearers. J Appl Oral Sci 2008, 16:385-90. 10.1590/S1678-77572008000600006, 19082396.
17. Xiang J, Zhu W, Li Z, Ling S. Effect of juice and fermented vinegar fromHovenia dulcispeduncles on chronically alcohol-induced liver damage in mice. Food Funct 2012, 3:628-34. 10.1039/c2fo10266h, 22648047.
18. Tochi BN, Wang Z, Xu S-Y, Zhang W. Therapeutic application of pineapple protease(bromelain): a review. Pak J Nutr 2008, 7:513-20. 10.3923/pjn.2008.513.520.
19. Mhatre M, Tilak-Jain J, De S, Devasagayam TPA. Evaluation of the antioxidant activity of non-transformed and transformed pineapple: a comparative study. Food Chem Toxicol 2009, 47:2696-702. 10.1016/j.fct.2009.06.031, 19563857.
20. Jacques DT, Marc KT, Marius A. Biochemical effectiveness in liver detoxication of fresh pineapple (Ananas comosus) with the wistar rats, previously intoxicated by Doliprane. J Cell AnimBiol 2008, 2:031-5.
21. Dougnon TJ, Kpodekon TM, Ahissou H, Gbenou J, Loko F, Laleye L. Protective effect of stem pineapple on Wistar rat poisoning with paracetamol. Int J Biol Chem Sci 2009, 3:688-93.
22. Olaleyea MT, Rocha BTJ. Acetaminophen-induced liver damage in mice: effects of some medicinal plants on the oxidative defense system. Exp Toxicol Pathol 2008, 59:319-27. 10.1016/j.etp.2007.10.003.
23. Moon Y-J, Choi D-S, Oh S-H, Song Y-S, Cha Y-S. Effects of persimmon-vinegar on lipid and carnitine profiles in mice. Food Sci Biotechnol 2010, 19:343-8. 10.1007/s10068-010-0049-3.
24. Yusof HM, Ali N, Yeap SK, Ho WY, Beh BK, Koh SP, et al. Hepatoprotective effect of fermented soybean (nutrient enriched soybean tempeh) against alcohol-induced liver damage in mice. Evid Based Complement Alternat Med 2013, 2013:1-9.
25. Y-h C, Yang C-M, Chang S-P, Hu M-L. C/EBP beta and C/EBP delta expression is elevated in the early phase of ethanol-induced hepatosteatosis in mice. Acta Pharmacol Sin 2009, 30:1138-43. 10.1038/aps.2009.109.
26. Lee KJ, You HJ, Park SJ, Kim YS, Chung YC, Jeong TC, et al. Hepatoprotective effects ofPlatycodon grandiflorumon acetaminophen-induced liver damage in mice. Cancer Lett 2001, 174:73-81. 10.1016/S0304-3835(01)00678-4, 11675154.
27. Ho WY, Yeap SK, Ho CL, Rahim RA, Alitheen NB. Hepatoprotective activity ofElephantopus scaberon alcohol-induced liver damage in mice. Evid Based Complement Alternat Med 2012, 2012:1-8.
28. Nagavani V, Rao TR. Evaluation of antioxidant potential and identification of polyphenolsby RP-HPLC inMichelia champacaflowers. Adv Biol Res 2010, 4:159-68.
29. Thaipong K, Boonprakob U, Crosby K, Cisneros-Zevallos L, Byrne DH. Comparison of ABTS, DPPH, FRAP, and ORAC assays for estimating antioxidant activity from guava fruit extracts. J Food Compos Anal 2006, 19:669-75. 10.1016/j.jfca.2006.01.003.
30. Basu S, Haldar N, Bhattacharya Sanji BS, Biswas M. Hepatoprotective activity ofLitchi chinensisleaves against paracetamol-induced liver damage in rats. Am-Eur J Sci Res 2012, 7:77-81.
31. Ozer J, Ratner M, Shaw M, Bailey W, Schomaker S. The current state of serum biomarkers of hepatotoxicity. Toxicology 2008, 245:194-205. 10.1016/j.tox.2007.11.021, 18291570.
32. Kang H, Koppula S. Hepatoprotective effect ofHouttuynia cordatathunb extract against carbon tetrachloride-induced hepatic damage in mice. Indian J Pharm Sci 2014, 76:267-73. 25284923.
33. Kim JY, Ok E, Kim YJ, Choi K-S, Kwon O. Oxidation of fatty acid may be enhanced by a combination of pomegranate fruit phytochemicals and acetic acid in HepG2 cells. Nutr Res Pract 2013, 7:153-9. 10.4162/nrp.2013.7.3.153, 23766874.
34. Kondo T, Kishi M, Fushimi T, Kaga T. Acetic acid upregulates the expression of genes for fatty acid oxidation enzymes in liver to suppress body fat accumulation. J Agric Food Chem 2009, 57:5982-6. 10.1021/jf900470c, 19469536.
35. Vitaglione P, Morisco F, Caporaso N, Fogliano V. Dietary antioxidant compounds and liver health. Crit Rev Food Sci Nutr 2004, 44:575-86. 10.1080/10408690490911701, 15969329.
36. Jeong C-H, Choi GN, Kim JH, Kwak JH, Kang S-T, Choi S-G, et al. In vitroantioxidant properties and phenolic composition of korean commercial vinegars. Food Sci Biotechnol 2009, 18:1258-a1262.
37. Cheedella HK, Alluri R, Ghanta KM. Hepatoprotective and antioxidant effect ofEcbolium viride(Forssk.) Alstonroots against paracetamol-induced hepatotoxicity in albino wistar rats. J Pharm Res 2013, 7:496-501. 10.1016/j.jopr.2013.06.001.
38. Sunil C, Duraipandiyan V, Ignacimuthu S, Al-Dhabib NA. Antioxidant, free radical scavenging and liver protective effects of friedelin isolated fromAzima tetracantha Lam.leaves. Food Chem 2013, 139:860-5. 10.1016/j.foodchem.2012.12.041, 23561182.
39. Arias-Salvatierra D, Silbergeld EK, Acosta-Saavedra LC, Calderon-Aranda ES. Role of nitric oxide produced by iNOS through NF-κB pathway in migration of cerebellar granule neurons induced by lipopolysaccharide. Cell Signal 2011, 23:425-35. 10.1016/j.cellsig.2010.10.017, 20955790.
40. Zamora R, Vodovotz Y, Billiar TR. Inducible nitric oxide synthase and inflammatory diseases. Mol Med 2000, 6:347-73. 10952018.
41. Ha K-T, Yoon S-J, Choi D-Y, Kim D-W, Kim J-K, Kim C-H. Protective effect ofLycium chinensefruit on carbon tetrachloride-induced hepatotoxicity. J Ethnopharmacol 2005, 96:529-35. 10.1016/j.jep.2004.09.054, 15619574.
42. Lee KJ, Woo E-R, Choi CY, Shin DW, Lee DG, You HJ, et al. Protective effect of acteoside on carbon tetrachloride-induced hepatotoxicity. Life Sci 2004, 74:1051-64. 10.1016/j.lfs.2003.07.020, 14672760.
43. Hwang J, Chang Y-H, Park JH, Kim SY, Chung H, Shim E, et al. Dietary saturated and monounsaturated fats protect against acute acetaminophen hepatotoxicity by altering fatty acid composition of liver microsomal membrane in rats. Lipids Health Dis 2011, 10:1-8. 10.1186/1476-511X-10-184.
44. Jeong SC, Kim SM, Jeong YT, Song CH. Hepatoprotective effect of water extract fromChrysanthemum indicumL.flower. Chin Med 2013, 8:1-8. 10.1186/1749-8546-8-7.
45. El-Beshbishy HA. Hepatoprotective effect of green tea (Camellia sinensis) extract against tamoxifen-induced liver injury in rats. J Biochem Mol Biol 2005, 38:563. 10.5483/BMBRep.2005.38.5.563, 16202236.
46. Zhao J, Chen H, Li Y. Protective effect of bicyclol on acute alcohol-induced liver injury in mice. Eur J Pharmacol 2008, 586:322-31. 10.1016/j.ejphar.2008.02.059, 18371952.
47. Hossaina MA, Rahman SMM. Total phenolics, flavonoids and antioxidant activity of tropical fruit pineapple. Food Res Int 2011, 44:672-6. 10.1016/j.foodres.2010.11.036.
48. Martinez MC, Afonso SG, Buzaleh AM. Batlle A: Protective action of antioxidants on hepatic damage induced by griseofulvin. Sci World J 2014, 2014:1-8.
49. Hunaefia D, Akumo DN, Smetanska I. Effect of fermentation on antioxidant properties of red cabbages. Food Biotechnol 2013, 27:66-85. 10.1080/08905436.2012.755694.
50. Martin LJ, Matar C. Increase of antioxidant capacity of the lowbush blueberry (Vaccinium angustifolium) during fermentation by a novel bacterium from the fruit microflora. J Sci Food Agric 2005, 85:1477-84. 10.1002/jsfa.2142.
51. Tung Y-T, Wu J-H, Huang C-C, Peng H-C, Chen Y-L, Yang S-C, et al. Protective effect ofAcacia confusabark extract and its active compound gallic acid against carbon tetrachloride-induced chronic liver injury in rats. Food Chem Toxicol 2009, 47:1385-92. 10.1016/j.fct.2009.03.021, 19327382.
52. Itoh A, Isoda K, Kondoh M, Kawase M, Watari A, Kobayashi M, et al. Hepatoprotective effect of syringic acid and vanillic acid on CCl4-induced liver injury. Biol Pharm Bull 2010, 33:983-7. 10.1248/bpb.33.983, 20522963.
53. Shin D-S, Kim KW, Chung HY, Yoon S, Moon J-O. Effect of sinapic acid against dimethylnitrosamine-induced hepatic fibrosis in rats. Arch Pharm Res 2013, 36:608-18. 10.1007/s12272-013-0033-6, 23435910.
54. Yanga S-Y, Honga C-O, b GPL, Kimc C-T, Lee K-W. The hepatoprotection of caffeic acid and rosmarinic acid, major compounds ofPerilla frutescens, against t-BHP-induced oxidative liver damage. Food Chem Toxicol 2013, 55:92-9. 10.1016/j.fct.2012.12.042.