Antithrombotic and fibrinolytic activities of methanolic extract of aged sorghum vinegar

Journal of Agricultural and Food Chemistry

Volumn 57, Issue 18, 2009, Pages 8683-8687

  Fan, Jufeng ^a   Zhang, Yanyan ^b   Chang, Xiaojie ^a   Zhang, Bolin ^a   Jiang, Da ^b   Saito, Masayoshi ^c   Li, Zaigui ^b  

^a BEIJING FORESTRY UNIVERSITY   (China)

^b CHINA AGRICULTURAL UNIVERSITY   (China)

^c JAPAN INTERNATIONAL RESEARCH CENTER FOR AGRICULTURAL SCIENCES   (Japan)

Author keywords

Aged vinegar; Antithrombotic activity; Sorghum

Indexed keywords

ACETIC ACID; ADENOSINE DIPHOSPHATE; ADRENALIN; ANTITHROMBOCYTIC AGENT; COLLAGEN; FIBRINOLYTIC AGENT; METHANOL; PHENOL DERIVATIVE;

ANIMAL; ARTICLE; BLOOD; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DRUG EFFECT; MALE; RABBIT; RAT; SORGHUM; THROMBOCYTE; THROMBOSIS;

ACETIC ACID; ADENOSINE DIPHOSPHATE; ANIMALS; BLOOD PLATELETS; COLLAGEN; EPINEPHRINE; FIBRINOLYTIC AGENTS; MALE; METHANOL; PHENOLS; PLATELET AGGREGATION INHIBITORS; RABBITS; RATS; SORGHUM; THROMBOSIS;

RATTUS;

EID: 70349329512     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf901680y     Document Type: Article

References (30)

1. Jin, Y. R.; Han, X. H.; Zhang, Y. H.; Lee, J. J.; Lim, Y.; Chung, J. H.; Yun, Y. P. Antiplatelet activity of hesperetin, a bioflavonoid, is mainly mediated by inhibition of PLC-γ2 phosphorylation and cyclooxygenase-1 activity. Atherosclerosis 2007, 194, 144-152.
2. Lee, J. J.; Jin, Y. R.; Lim, Y.; Hong, J. T.; Kim, T. J.; Chung, J. H.; Yun, Y. P. Antiplatelet activity of carnosol is mediated by the inhibition of TXA2 receptor and cytosolic calcium mobilization. Vase Pharmacol. 2006, 45, 148-153.
3. Jackson, S. P.; Nesbitt, W. S.; Kulkami, S. Signaling events underlying thrombus formation. J. Thromb. Haemost. 2003, 1, 1602-1612.
4. Ross, R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993, 362, 801-809.
5. Ruggeri, Z. M. Platelets in atherothrombosis. Nat. Med. 2002, 11, 1227-1234.
6. Xu, Q. P.; Ao, Z. H.; Tao, W. Y. Progress in vinegar function study. China Condiment 2003, 12, 11-12 (in Chinese).
7. Fushimi, T.; Tayama, K.; Fukaya, M.; Kitakoshi, K.; Nakai, N.; Tsukamoto, Y.; Saito, Y. Acetic acid feeding enhances glycogen repletion in liver and skeletal muscle of rats. J. Nutr. 2001, 131, 1973-1977.
8. Ebihara, K.; Nakajima, A. Effect of acetic acid and vinegar on blood glucose and insulin responses to orally administered sucrose and starch. Agric. Biol. Chem. 1998, 52, 1311-1312.
9. Kondo, S.; Tayama, K.; Tsukamoto, Y.; Ikeda, K.; Yamori, Y. Antihypertensive effects of acetic acid and vinegar on spontaneously hypertensive rats. Biosci., Biotechnol, Biochem. 2001, 65, 2690-2694.
10. Liljeberg, H.; Bjorck, I. Delayed gastric emptying rate may explain improved glycaemia in healthy subjects to a starchy meal with added vinegar. Eur. J. Clin. Nutr. 1998, 52, 368-371.
11. Kishi, M.; Fukaya, M.; Tsukamoto, Y.; Nagasawa, T.; Takehana, K.; Nishizawa, N. Enhancing effect of dietary vinegar on the intestinal absorption of calcium in ovariectomized rats. Biosci., Biotechnol, Biochem. 1999, 163, 905-910.
12. Nishidai, S.; Nakamura, Y.; Torikai, K. Kurosu, a traditional vinegar produced from unpolished rice, suppresses lipid peroxidation in vitro and in mouse skin. Biosci., Biotechnol, Biochem. 2000, 64, 1909-1914.
13. Shimoji, Y.; Tamura, Y.; Nakamura, Y.; Nanda, K.; Nishidai, S.; Nishikawa, Y.; Ishihara, N.; Uenakai, K.; Ohigashi, H. Isolation and identification of DPPH radical scavenging compounds in Kurosu (Japanese unpolished rice vinegar). J. Agric. Food Chem. 2002, 50, 6501-6503.
14. He, Z. Y.; Ao, Z. H.; Wu, J.; Li, G. Q.; Tao, W. Y. Determination and generant mechanism of tetramethylpyrazine in Zhenjiang vinegar. China Condiment 2004, 300, 36-39.
15. Xu, Q. P.; Tao, W. Y.; Ao, Z. H. Antioxidant activity of vinegar melanoidins. Food Chem. 2007, 102, 841-849.
16. Yamagishi, K.; Kimura, T.; Kameyama, M.; Nagata, T.; Kikuchi, Y. Purification and identification of blood fluidity improvement factor in brewed rice vinegar (Kurosu). Nippon Shokushi Kagaku Kogaku Kaishi 1998, 45, 545-549 (in Japanese).
17. Peterson, D. M.; Emmons, C. L.; Hibbs, A. H. Phenolic antioxidants and antioxidant activity in pearling fractions of oat groats. J. Cereal Sci. 2001, 33, 97-103.
18. Zhishen, J.; Mengeheng, T.; Jianming, W. The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals. Food Chem. 1999, 64, 555-559.
19. Horn, F.; dos Santos, P.; Termignoni, C. Boophilus microplus anticoagulant protein: an antithrombin inhibitor isolated from the cattle tick saliva. Arch. Biochem. Biophys. 2000, 384, 68-73.
20. DiMinno, G.; Silver, M. J. Mouse antithrombotic assay: a simple method for the evaluation of antithrombotic agents in vivo. Potentiation of antithrombotic activity by ethyl alcohol. J. Pharmacol. Exp. Ther. 1983, 225, 57-60.
21. Omura, K.; Hitosugi, M.; Zhu, X.; Ikeda, M.; Maeda, H.; Tokudome, S. A newly derived protein from Bacillus subtilis natto with both antithrombotic and fibrinolytic effects. J. Pharmacol. Sci. 2005, 99, 247-251.
22. Kim, M.S.; Lee, K. A. Antithrombotic activity of methanolic extract of Umbilicaria esculenta. J. Ethnopharmacol. 2006, 105, 342-345.
23. Bhatt, D. L.; Topol, E. J. Scientific and therapeutic advances in antiplatelet therapy. Nat. Rev. Drug Discovery 2003, 2, 15-28.
24. Jackson, S. P.; Schoenwaelder, S. M. Antiplatelet therapy: in search of the "magic bullet". Nat. Rev. Drug Discovery 2003, 2, 1-15.
25. Wu, C. C.; Wang, T. W.; Wang, W. Y.; Hsieh, P. W.; Wu, Y. C. 2-(2-Br-phenyl)-8-methoxy-benzoxazinone (HPW-RX2), a direct thrombin inhibitor with a suppressive effect on thromboxane formation in platelets. Eur. J. Pharmacol. 2005, 527, 37-43.
26. Tzeng, S. H.; Ko, W. C.; Ko, F. N.; Teng, C. M. Inhibition of platelet aggregation by some flavonoids. Thromb. Res. 1991, 64, 91-100.
27. Petroni, A.; Blasevich, M.; Salami, M.; Papini, N.; Montedoro, G. F.; Galli, C. Inhibition of platelet aggregation and eicosanoid production by phenolic components of Oliver oil. Thromb. Res. 1995, 78, 151-160.
28. Kang, W. S.; Lim, I. H.; Yuk, D. Y.; Chung, K. H.; Park, J. B.; Yoo, H. S.; Yun, Y. P. Antithrombotic activities of green tea catechins and (-)-epigallocatechin gállate. Thromb. Res. 1999, 96, 229-237.
29. Hubbard, G. P.; Wolffram, S.; Lovegrove, J. A.; Gibbins, J. M. Ingestion of quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in humans. J. Thromb. Haemost. 2004, 2, 2138-2145.
30. Stang, V.; Lorenz, M.; Ludwig, A.; Grimbo, N.; Guether, C.; Sanad, W.; Ziemer, S.; Martus, P.; Baumann, G.; Stangl, K. The flavonoid phloretin suppresses stimulated expression of endothelial adhesion molecules and reduces activation of human platelets. J. Nutr. 2005, 135, 172-178.