Protective Effect of Acteoside on Carbon Tetrachloride-Induced Hepatotoxicity

Life Sciences

Volumn 74, Issue 8, 2004, Pages 1051-1064

  Lee, Kyung Jin ^a   Woo, Eun Rhan ^a   Choi, Chul Yung ^b   Shin, Dong Weon ^a   Lee, Dong Gun ^c   You, Ho Jin ^a   Jeong, Hye Gwang ^a  

^a Chosun University   (South Korea)

^b Jinju International University   (South Korea)

^c Kyungpook National University   (South Korea)

Author keywords

Acteoside; Antioxidant; Carbon tetrachloride; Cytochrome P450 2E1; Hepatoprotective effects

Indexed keywords

ACTEOSIDE; ALANINE; ANILINE; ANTIOXIDANT; ASCORBIC ACID; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; CYTOCHROME P450 2E1; FERRIC CHLORIDE; GLUTATHIONE; GLYCOSIDE; ISOENZYME; LIPID; MALONALDEHYDE; NITROPHENOL; SCAVENGER; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; HISTOPATHOLOGY; HYDROXYLATION; LIPID PEROXIDATION; LIVER HOMOGENATE; LIVER PROTECTION; LIVER TOXICITY; MALE; NONHUMAN;

EID: 0347481468     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2003.07.020     Document Type: Article

References (36)

1. Allis J.W., Brown B.L., Simmons J.E., Hatch G.E., McDonald A., House D.E. Methanol potentiation of carbon tetrachloride hepatotoxicity: the central role of cytochrome P450. Toxicology. 112:1996;131-140.
2. Boyer T.D., Vessey D.A., Holcomb C., Saley N. Studies of the relationship between the catalytic activity and binding of non-substrate ligands by the glutathione S-transferases. Biochemical Journal. 217:1984;179-185.
3. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry. 72:1976;248-254.
4. Brattin W.J., Glende E.A.Jr., Recknagel R.O. Pathological mechanisms in carbon tetrachloride hepatotoxicity. Free Radical Biology and Medicine. 1:1985;27-38.
5. Brautbar N., Williams J. 2nd Industrial solvents and liver toxicity: risk assessment, risk factors and mechanisms. International Journal of Hygiene and Environmental Health. 205:2002;479-491.
6. Brent J.A., Rumack B.H. Role of free radicals in toxic hepatic injury 11. Clinical Toxicology. 31:1993;173-196.
7. Campo G.M., Squadrito F., Ceccarelli S., Calo M., Avenoso A., Campo S., Squadrito G., Altavilla D. Reduction of carbon tetrachloride-induced rat liver injury by IRFI 042, a novel dual vitamin E-like antioxidant. Free Radical Research. 34:2001;379-393.
8. Dicker E., McHugh T., Cederbaum A.I. Increased oxidation of p-nitrophenol and aniline by intact hepatocytes isolated from pyrazole-treated rats. Biochimica et Biophysica ACTA. 1035:1990;249-256.
9. Eaton D.L., Gallagher E.P., Bammler T.K., Kunze K.L. Role of cytochrome P4501A2 in chemical carcinogenesis: Implications for human variability in expression and enzyme activity. Pharmacogenetics. 5:1995;259-274.
10. Fairhurst S., Barber D.J., Clark B., Horton A.A. Studies on paracetamol-induced lipid peroxidation. Toxicology. 23:1982;249-259.
11. Gonzalez F.J. The molecular biology of cytochrome P450s. Pharmacological Reviews. 40:1988;243-288.
12. Guengerich F.P., Kim D.-H., Iwasaki M. Role of human cytochrome P-450 IIE 1 in the oxidation of many low molecular weight cancer suspects. Chemical Research in Toxicology. 4:1991;168-179.
13. Habig W.H., Pablst M.J., Jakoby W.B. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. Journal of Biological Chemistry. 49:1974;7130-7139.
14. Hayashi K., Nagamatsu T., Ito M., Hattori T., Suzuki Y. Acteoside, a component of Stachys sieboldii MIQ, may be a promising antinephritic agent (2): Effect of acteoside on leukocyte accumulation in the glomeruli of nephritic rats. Japanese Journal of Pharmacology. 66:1994;47-52.
15. Houghton P.J. Ethnopharmacology of some Buddleia species. Journal of Ethnopharmacology. 11:1984;293-308.
16. Houghton P.J., Woldemariam T.Z., Candau M., Barnardo A., Khen-Alafun O., Shangxiao L. Buddlejone, a diterpene from Buddleja albiflora. Phytochemistry. 42:1996;485-488.
17. Inoue M., Sakuma Z., Ogihara Y., Saracoglu I. Induction of apoptotic cell death in HL-60 cells by acteoside, a phenylpropanoid glycoside. Biological and Pharmaceutical Bulletin. 21:1998;81-83.
18. Jeong H.G. Inhibition of cytochrome P450 2E1 expression by oleanolic acid: Hepatoprotective effects against carbon tetrachloride-induced hepatic injury. Toxicology Letters. 105:1999;215-222.
19. Jeong H.G., Yun C.H. Induction of rat hepatic cytochrome enzymes by myristicin. Biochemical and Biophysical Research Communications. 217:1995;966-971.
20. Kim N.D., Kwak M.K., Kim S.G. Inhibition of cytochrome P450 2E1 expression by 2-(allylthio)pyrazine, a potential chemoprotective agent: hepatoprotective effects. Biochemical Pharmacology. 53:1997;261-269.
21. Kim S.G., Novak R.F. Induction of rat hepatic P450IIE1 (CYP 2E1) by pyridine: evidence for a role of protein synthesis in the absence of transcriptional activation. Biochemical and Biophysical Research Communications. 166:1990;1072-1079.
22. Koop D.R. Oxidative and reductive metabolism by cytochrome P450 2E1. FASEB Journal. 6:1992;724-730.
23. Lee S.S.T., Buters J.T.M., Pineau T., Femandez-Salguero P., Gonzalez F.J. Role of CYP2E1 in the hepatotoxicity of acetaminophen. Journal of Biological Chemistry. 271:1996;12063-12067.
24. Ohno T., Inoue M., Ogihara Y., Saracoglu I. Antimetastatic activity of acteoside, a phenylethanoid glycoside. Biological and Pharmaceutical Bulletin. 25:2002;666-668.
25. Recknagel R.O., Glende E.A. Jr., Britton R.S. Free radical damage and lipid peroxidation. Meeks R.G. Hepatotoxicology. 1991;401-436 CRC Press, Florida.
26. Recknagel R.O., Glende E.A. Jr., Dolak J.A., Waller R.L. Mechanisms of carbon tetrachloride toxicity. Pharmacology and Therapeutics. 43:1989;139-154.
27. Schapoval E.E., Vargas M.R., Chaves C.G., Bridi R., Zuanazzi J.A., Henriques A.T. Antiinflammatory and antinociceptive activities of extracts and isolated compounds from Stachytarpheta cayennensis. Journal of Ethnopharmacology. 60:1998;53-59.
28. Sedlak J., Lindsay R.H. Estimation of total protein with bound and non-protein sulthydryl groups in tissues with Ellman's reagent. Analytical Biochemistry. 25:1968;192-205.
29. Ursini F., Maiorino M., Morazzoni P., Roveri A., Pifferi G. A novel antioxidant flavonoid affecting molecular mechanisms of cellular activation. Free Radical Biology and Medicine. 16:1994;547-553.
30. Williams A.T., Burk R.F. Carbon tetrachloride hepatotoxicity: an example of free radical-mediated injury. Seminars in Liver Disease. 10:1990;279-284.
31. Wong I.Y., He Z.D., Huang Y., Chen Z.Y. Antioxidative activities of phenylethanoid glycosides from Ligustrum purpurascens. Journal of Agricultural and Food Chemistry. 49:2001;3113-3119.
32. Xiong Q., Hase K., Tezuka Y., Namba T., Kadota S. Acteoside inhibits apoptosis in D-galactosamine and lipopolysaccharide-induced liver injury. Life Sciences. 65:1999;421-430.
33. Xiong Q., Hase K., Tezuka Y., Tani T., Namba T., Kadota S. Hepatoprotective activity of phenylethanoids from Cistanche deserticola. Planta Medica. 64:1998;120-125.
34. Xiong Q., Kadota S., Tani T., Namba T. Antioxidative effects of phenylethanoids from Cistanche deserticola. Biological and Pharmaceutical Bulletin. 19:1996;1580-1585.
35. Yang C.S., Yoo J.S.H., Ishizaki H., Hong J.-Y. Cytochrome P450 IIE1: Roles in nitrosamine metabolism and mechanism of regulation. Drug Metabolism Reviews. 22:1990;147-159.
36. Zangar R.C., Benson J.M., Burnett V.L., Springer D.L. Cytochrome P450 2E1 is the primary enzyme responsible for low-dose carbon tetrachloride metabolism in human liver microsomes. Chemico-Biological Interactions. 125:2000;233-243.