Activated platelets release sphingosine 1-phosphate and induce hypersensitivity to noxious heat stimuli in vivo

Frontiers in Neuroscience

Volumn 9, Issue APR, 2015, Pages

  Weth, Daniela ^a   Benetti, Camilla ^a   Rauch, Caroline ^a   Gstraunthaler, Gerhard ^a   Schmidt, Helmut ^b   Geisslinger, Gerd ^b   Sabbadini, Roger ^c   Proia, Richard L ^d   Kress, Michaela ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b Pharmazentrum Frankfurt/ZAFES   (Germany)

^c Lpath Inc   (United States)

^d NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Heat nociception; Platelet; Post operative pain; S1P receptors; Sphingosine 1 phosphate

Indexed keywords

SPHINGOSINE 1 PHOSPHATE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GENE MUTATION; HEAT HYPERSENSITIVITY; HEAT SENSITIVITY; HUMAN; HUMAN CELL; HYPERSENSITIVITY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; MALE; MOUSE; NONHUMAN; TANDEM MASS SPECTROMETRY; THERMAL STIMULATION; THROMBOCYTE ACTIVATION; THROMBOCYTE COUNT;

EID: 84928672026     PISSN: 16624548     EISSN: 1662453X     Source Type: Journal    
DOI: 10.3389/fnins.2015.00140     Document Type: Article

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