Mechanisms underlying the nociceptive responses induced by platelet-activating factor (PAF) in the rat paw

Biochemical Pharmacology

Volumn 77, Issue 7, 2009, Pages 1223-1235

  Marotta, Denise M ^a   Costa, Robson ^a   Motta, Emerson M ^a   Fernandes, Elizabeth S ^a   Medeiros, Rodrigo ^a   Quintão, Nara L M ^a   Campos, Maria M ^b   Calixto, João B ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Leukocytes; Mechanical hypersensitivity; Platelet activating factor (PAF); Spontaneous nociception

Indexed keywords

1 (2 BROMOPHENYL) 3 (2 HYDROXY 4 NITROPHENYL)UREA; 4 CHLORO N (3 METHOXYPHENYL)CINNAMAMIDE; ANTIINFLAMMATORY AGENT; APAFANT; ATENOLOL; CD88 ANTIBODY; CELECOXIB; COMPLEMENT COMPONENT C5A RECEPTOR; COMPOUND 48-80; FUCOIDIN; GRANULOCYTE ANTIBODY; INDOMETACIN; INTERLEUKIN 1BETA ANTIBODY; MACROPHAGE ANTIBODY; MONOCLONAL ANTIBODY; MYELOPEROXIDASE; PROSTAGLANDIN SYNTHASE INHIBITOR; RESINIFERATOXIN; SELECTIN; THROMBOCYTE ACTIVATING FACTOR; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; ENZYME ACTIVITY; MALE; MAST CELL; NEUTROPHIL; NOCICEPTION; NONHUMAN; PATHOPHYSIOLOGY; PAW EDEMA; PRIORITY JOURNAL; PROTEIN TARGETING; RAT;

ANIMALS; AZEPINES; FORELIMB; MALE; PAIN; PAIN MEASUREMENT; PLATELET ACTIVATING FACTOR; PLATELET MEMBRANE GLYCOPROTEINS; RATS; RATS, WISTAR; RECEPTORS, G-PROTEIN-COUPLED; TRIAZOLES;

EID: 61449124821     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.12.025     Document Type: Article

References (67)

1. Ishii S., and Shimizu T. Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice. Prog Lipid Res 39 (2000) 41-82
2. Ishii S., Nagase T., and Shimizu T. Platelet-activating factor receptor. Prostaglandins Other Lipid Mediat 68-69 (2002) 599-609
3. Honda Z., Ishii S., and Shimizu T. Platelet-activating factor receptor. J Biochem 131 (2002) 773-779
4. Zimmerman G.A., McIntyre T.M., Prescott S.M., and Stafforini D.M. The platelet-activating factor signaling system and its regulators in syndromes of inflammation and thrombosis. Crit Care Med 30 (2002) S294-S301
5. De Plaen I.G., Tan X.D., Chang H., Qu X.W., Liu Q.P., and Hsueh W. Intestinal NF-κB is activated, mainly as p50 homodimers, by platelet-activating factor. Biochim Biophys Acta 1392 (1998) 185-192
6. De Plaen I.G., Tan X.D., Chang H., Wang L., Remick D.G., and Hsueh W. Lipopolysaccharide activates nuclear factor-κB in rat intestine: role of endogenous platelet-activating factor and tumour necrosis factor. Br J Pharmacol 129 (2000) 307-314
7. 1 receptors in the rat paw. Br J Pharmacol 139 (2003) 973-981
8. 1 receptor expression. Br J Pharmacol 146 (2005) 209-216
9. Zhou W., Javors M.A., and Olson M.S. Impaired surface expression of PAF receptors on human neutrophils is dependent upon cell activation. Arch Biochem Biophys 308 (1994) 439-445
10. Franciose R.J., Moore E.E., Moore F.A., Read R.A., Carl V.S., and Banerjee A. Hypoxia/reoxygenation of human endothelium activates PMNs to detach endothelial cells via a PAF mechanism. J Surg Res 61 (1996) 459-462
11. Chao W., and Olson M.S. Platelet-activating factor: receptors and signal transduction. Biochem J 292 (1993) 617-629
12. Korth R.M., Hirafuji M., Benveniste J., and Russo-Marie F. Human umbilical vein endothelial cells: specific binding of platelet-activating factor and cytosolic calcium flux. Biochem Pharmacol 49 (1995) 1793-1799
13. Tokutomi T., Maruiwa H., Hirohata M., Miyagi T., and Shigemori M. Production of platelet-activating factor by neuronal cells in the rat brain with cold injury. Neurol Res 23 (2001) 605-611
14. Poubelle P.E., Gingras D., Demers C., Dubois C., Harbour D., Grassi J., et al. Platelet-activating factor (PAF-acether) enhances the concomitant production of tumour necrosis factor-alpha and interleukin-1 by subsets of human monocytes. Immunology 72 (1991) 181-187
15. Ruis N.M., Rose J.K., and Valone F.H. Tumor necrosis factor release by human monocytes stimulated with platelet-activating factor. Lipids 26 (1991) 1060-1064
16. Aepfelbacher M., Ziegler-Heitbrock H.W., Lux I., and Weber P.C. Bacterial lipopolysaccharide up-regulates platelet-activating factor-stimulated Ca2+ mobilization and eicosanoid release in human Mono Mac 6 cells. J Immunol 148 (1992) 2186-2193
17. Roth M., Nauck M., Yousefi S., Tamm M., Blaser K., Perruchoud A.P., et al. Platelet-activating factor exerts mitogenic activity and stimulates expression of interleukin 6 and interleukin 8 in human lung fibroblasts via binding to its functional receptor. J Exp Med 184 (1996) 191-201
18. Marrache A.M., Gobeil, Bernier S.G., Stankova J., Rola-Pleszczynski M., Choufani S., et al. Proinflammatory gene induction by platelet-activating factor mediated via its cognate nuclear receptor. J Immunol 169 (2002) 6474-6481
19. Morita K., Morioka N., Abdin J., Kitayama S., Nakata Y., and Dohi T. Development of tactile allodynia and thermal hyperalgesia by intrathecally administered platelet-activating factor in mice. Pain 111 (2004) 351-359
20. 2 release from astrocyte-enriched cortical cell cultures. Brain Res 946 (2002) 87-95
21. Vargaftig B.B., and Ferreira S.H. Blockade of the inflammatory effects of platelet-activating factor by cyclo-oxygenase inhibitors. Braz J Med Biol Res 14 (1981) 187-189
22. Dallob A., Guindon Y., and Goldenberg M.M. Pharmacological evidence for a role of lipoxygenase products in platelet-activating factor (PAF)-induced hyperalgesia. Biochem Pharmacol 36 (1987) 3201-3204
23. Humphrey D.M., McManus L.M., Satouchi K., and Hanahan D. Vasoactive properties of acetyl glyceryl ether phosphorylcholine and analogues. Lab Invest 46 (1982) 422-427
24. O'Flaherty J.T., Surles J.R., Redman J., Jacobson D., Piantadosi C., and Wykle R.L. Binding and metabolism of platelet-activating factor by human neutrophils. J Clin Invest 78 (1986) 381-388
25. Teixeira C.F., Cury Y., Oga S., and Jancar S. Hyperalgesia induced by Bothrops jararaca venom in rats: role of eicosanoids and platelet activating factor (PAF). Toxicon 32 (1994) 419-426
26. Teather L.A., Magnusson J.E., and Wurtman R.J. Platelet-activating factor antagonists decrease the inflammatory nociceptive response in rats. Psychopharmacology 163 (2002) 430-433
27. Tsuda M., Ishii S., Masuda T., Hasegawa S., Nakamura K., Nagata K., et al. Reduced pain behaviors and extracellular signal-related protein kinase activation in primary sensory neurons by peripheral tissue injury in mice lacking platelet-activating factor receptor. J Neurochem 102 (2007) 1658-1668
28. Zhang Q., Sitzman L.A., Al-Hassani M., Cai S., Pollok K.E., Travers J.B., et al. Involvement of platelet-activating factor in ultraviolet B-induced hyperalgesia. J Invest Dermatol (2008) [Epub ahead of print]
29. Tjölsen A., Berge O.G., Hunskaar S., Rosland J.H., and Hole K. The formalin test: an evaluation of the method. Pain 51 (1992) 5-17
30. 2 in endotoxin-induced localized inflammatory hyperalgesia. Br J Pharmacol 121 (1997) 1619-1626
31. Nagakura Y., Okada M., Kohara A., Kiso T., Toya T., Iwai A., et al. Allodynia and hyperalgesia in adjuvant-induced arthritic rats: time course of progression and efficacy of analgesics. J Pharmacol Exp Ther 306 (2003) 490-497
32. Perkins N.M., and Tracey D.J. Hyperalgesia due to nerve injury: role of neutrophils. Neuroscience 101 (2000) 745-757
33. 1 receptor up-regulation after lipopolysaccharide administration: role of proinflammatory cytokines and neutrophil influx. J Immunol 172 (2004) 1839-1847
34. Woolf C.J., Ma Q.P., Allchorne A., and Poole S. Peripheral cell types contributing to the hyperalgesic action of the nerve growth factor of inflammation. J Neurosci 16 (1996) 2716-2723
35. Tender G.C., Walbridge S., Olah Z., Karai L., Iadarola E.H., and Lonser R.R. Selective ablation of nociceptive neurons for elimination of hyperalgesia and neurogenic inflammation. J Neurosurg 102 (2005) 522-525
36. Ikeda Y., Ueno A., Naraba H., and Oh-Ishi S. Involvement of vanilloid receptor VR1 and prostanoids in the acid-induced writhing response of mice. Life Sci 69 (2001) 2911-2919
37. White J.R., Lee J.M., Young P.R., Hertzberg R.P., Jurewicz A.J., Chaikin M.A., et al. Identification of a potent, selective non-peptide CXCR2 antagonist that inhibits interleukin-8-induced neutrophil migration. J Biol Chem 273 (1998) 10095-10098
38. Verri Jr. W.A., Cunha T.M., Parada C.A., Poole S., Cunha F.Q., and Ferreira S.H. Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development?. Pharmacol Ther 112 (2006) 116-138
39. Cunha T.M., Verri Jr. W.A., Silva J.S., Poole S., Cunha F.Q., and Ferreira S.H. A cascade of cytokines mediates mechanical inflammatory hypernociception in mice. Proc Natl Acad Sci USA 102 (2005) 1755-1760
40. Safieh-Garabedian B., Poole S., Allchorne A., Winter J., and Woolf C.J. Contribution of interleukin-1 beta to the inflammation-induced increase in nerve growth factor levels and inflammatory hyperalgesia. Br J Pharmacol 115 (1995) 1265-1275
41. Sommer C., and Kress M. Recent findings on how proinflammatory cytokines cause pain: peripheral mechanisms in inflammatory and neuropathic hyperalgesia. Neurosci Lett 361 (2004) 184-187
42. Kawasaki Y., Zhang L., Cheng J.K., and Ji R.R. Cytokine mechanisms of central sensitization: distinct and overlapping role of interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in regulating synaptic and neuronal activity in the superficial spinal cord. J Neurosci 28 (2008) 5189-5194
43. Ferreira S.H., Lorenzetti B.B., Bristow A.F., and Poole S. Interleukin-1 beta as a potent hyperalgesic agent antagonized by a tripeptide analogue. Nature 334 (1988) 698-700
44. Fukuoka H., Kawatani M., Hisamitsu T., and Takeshige C. Cutaneous hyperalgesia induced by peripheral injection of interleukin-1 beta in the rat. Brain Res 657 (1994) 133-140
45. 9bradykinin-mediated thermal hyperalgesia in the rat. Neuropharmacology 33 (1994) 657-660
46. Oprée A., and Kress M. Involvement of the proinflammatory cytokines tumor necrosis factor-alpha, IL-1 beta, and IL-6 but not IL-8 in the development of heat hyperalgesia: effects on heat-evoked calcitonin gene-related peptide release from rat skin. J Neurosci 20 (2000) 6289-6293
47. Schäfers M., Lee D.H., Brors D., Yaksh T.L., and Sorkin L.S. Increased sensitivity of injured and adjacent uninjured rat primary sensory neurons to exogenous tumor necrosis factor-alpha after spinal nerve ligation. J Neurosci 23 (2003) 3028-3038
48. Fehrenbacher J.C., Burkey T.H., Nicol G.D., and Vasko M.R. Tumor necrosis factor alpha and interleukin-1beta stimulate the expression of cyclooxygenase II but do not alter prostaglandin E2 receptor mRNA levels in cultured dorsal root ganglia cells. Pain 113 (2005) 113-122
49. von Banchet G.S., Kiehl M., and Schaible H.G. Acute and long-term effects of IL-6 on cultured dorsal root ganglion neurons from adult rat. J Neurochem 94 (2005) 238-248
50. Calixto J.B., Kassuya C.A., André E., and Ferreira J. Contribution of natural products to the discovery of the transient receptor potential (TRP) channels family and their functions. Pharmacol Ther 106 (2005) 179-208
51. Huang J., Zhang X., and McNaughton P.A. Inflammatory pain: the cellular basis of heat hyperalgesia. Curr Neuropharmacol 4 (2006) 197-206
52. Cunha T.M., Barsante M.M., Guerrero A.T., Verri Jr. W.A., Ferreira S.H., Coelho F.M., et al. Treatment with DF 2162, a non-competitive allosteric inhibitor of CXCR1/2, diminishes neutrophil influx and inflammatory nociception in mice. Br J Pharmacol 154 (2008) 460-470
53. Ohashi K., Sato Y., Kawai M., and Kurebayashi Y. Abolishment of TNBS-induced visceral hypersensitivity in mast cell deficient rats. Life Sci 82 (2008) 419-423
54. Paszcuk A.F., Quintão N.L., Fernandes E.S., Juliano L., Chapman K., Andrade-Gordon P., et al. Mechanisms underlying the nociceptive and inflammatory responses induced by trypsin in the mouse paw. Eur J Pharmacol 581 (2008) 204-215
55. Ständer S., Moormann C., Schumacher M., Buddenkotte J., Artuc M., Shpacovitch V., et al. Expression of vanilloid receptor subtype 1 in cutaneous sensory nerve fibers, mast cells, and epithelial cells of appendage structures. Exp Dermatol 13 (2004) 129-139
56. Rousseau S., Dolado I., Beardmore V., Shpiro N., Marquez R., Nebreda A.R., et al. CXCL12 and C5a trigger cell migration via a PAK1/2-p38alpha MAPK-MAPKAP-K2-HSP27 pathway. Cell Signal 18 (2006) 1897-1905
57. Twining C.M., Sloane E.M., Schoeniger D.K., Milligan E.D., Martin D., Marsh H., et al. Activation of the spinal cord complement cascade might contribute to mechanical allodynia induced by three animal models of spinal sensitization. J Pain 6 (2005) 174-183
58. Clark J.D., Qiao Y., Li X., Shi X., Angst M.S., and Yeomans D.C. Blockade of the complement C5a receptor reduces incisional allodynia, edema, and cytokine expression. Anesthesiology 104 (2006) 1274-1282
59. Griffin R.S., Costigan M., Brenner G.J., Ma C.H., Scholz J., Moss A., et al. Complement induction in spinal cord microglia results in anaphylatoxin C5a-mediated pain hypersensitivity. J Neurosci 27 (2007) 8699-8708
60. Abbadie C. Chemokines, chemokine receptors and pain. Trends Immunol 26 (2005) 529-534
61. Cunha F.Q., Lorenzetti B.B., Poole S., and Ferreira S.H. Interleukin-8 as a mediator of sympathetic pain. Br J Pharmacol 104 (1991) 765-767
62. Harris E.S., McIntyre T.M., Prescott S.M., and Zimmerman G.A. The leukocyte integrins. J Biol Chem 275 (2000) 23409-23412
63. Yonekawa K., and Harlan J.M. Targeting leukocyte integrins in human diseases. J Leukoc Biol 77 (2005) 129-140
64. Cunha F.Q., and Ferreira S.H. Peripheral hyperalgesic cytokines. Adv Exp Med Biol 521 (2003) 22-39
65. Coutaux A., Adam F., Willer J.C., and Le Bars D. Hyperalgesia and allodynia: peripheral mechanisms. Joint Bone Spine 72 (2005) 359-371
66. Smith H.S. Arachidonic acid pathways in nociception. J Support Oncol 4 (2006) 277-287
67. Rodrigues L.L., Oliveira M.C., Pelegrini-da-Silva A., de Arruda Veiga M.C., Parada C.A., and Tambeli C.H. Peripheral sympathetic component of the temporomandibular joint inflammatory pain in rats. J Pain 7 (2006) 929-936