Effects of local serotonin administration on pain and microcirculation in the human masseter muscle

Journal of Orofacial Pain

Volumn 20, Issue 3, 2006, Pages 241-248

  Ernberg, Malin ^a   Hedenberg Magnusson, Britt ^b   Kurita, Hiroshi ^c   Kopp, Sigvard ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Eastman Dental Institute Stockholm   (Sweden)

^c SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Ischemia; Laser Doppler flowmetry; Masseter muscle; Pain; Serotonin

Indexed keywords

SEROTONIN; SEROTONIN RECEPTOR AFFECTING AGENT;

ANALYSIS OF VARIANCE; ARTICLE; BLOOD FLOW; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FACE PAIN; FEMALE; HUMAN; MASSETER MUSCLE; MICROCIRCULATION; MIDDLE AGED; NONPARAMETRIC TEST; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; VASCULARIZATION;

ANALYSIS OF VARIANCE; DOUBLE-BLIND METHOD; FACIAL PAIN; FEMALE; HUMANS; MASSETER MUSCLE; MICROCIRCULATION; MIDDLE AGED; REGIONAL BLOOD FLOW; SEROTONIN; SEROTONIN AGENTS; STATISTICS, NONPARAMETRIC;

EID: 33747591223     PISSN: 10646655     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. LeResche L. Epidemiology of temporomandibular disorders. Implications for the investigation of etiologic factors. Crit Rev Oral Biol Med 1997;8:291-305.
2. Sessle BJ. The neural basis of temporomandibular joint and masticatory muscle pain. J Orofac Pain 1999;13:238-245.
3. Foreman PA. Temporomandibular joint and myofascial pain dysfunction-Some current concepts. Part 1: Diagnosis. N Z Dent J 1985;81:47-52.
4. Larsson SE, Bodegård L, Henriksson KG, Öberg PA. Chronic trapezius myalgia. Morphology and blood flow studied in 17 patients. Acta Orthop Scand 1990;61:394-398.
5. Larsson SE, Cai H, Öberg PA. Microcirculation in the upper trapezius muscle during varying levels of static contraction, fatigue and recovery in healthy women-A study using percutaneous laser-Doppler flowmetry and surface electromyography. Eur J Appl Physiol 1993;66:483-488.
6. Larsson R, Öberg PA, Larsson SE. Changes of trapezius muscle blood flow and electromyography in chronic neck pain due to trapezius myalgia. Pain 1999;79:45-50.
7. Mense S. The pathogenesis of muscle pain. Curr Pain Headache Rep 2003;7:419-425.
8. Dubner R, Ren K. Brainstem mechanisms for the initiation of pain following trigeminal nerve injury. J Orofac Pain 2004;18:299-305.
9. Sessle BJ. Acute and chronic craniofacial pain: Brainstem mechanisms of nociceptive transmission and neuroplasticity and their clinical correlates. Crit Rev Oral Biol Med 2000;11:57-91.
10. Yu X-M, Sessle BJ, Haas DA, Izzo A, Vernon H, Hu JW. Involvement of NMDA receptor mechanisms in jaw electromyographic activity and plasma extravasation induced by inflammatory irritant application to temporomandibular joint region of rats. Pain 1996;68:169-178.
11. Hellstrom F, Thunberg J, Bergenheim M, Sjolander P, Pedersen J, Johansson H. Elevated intramuscular concentration of bradykinin in jaw muscle increases the fusimotor drive to neck muscles in the cat. J Dent Res 2000;79:1815-1822.
12. Ernberg M, Hedenberg-Magnusson B, Alstergren P, Kopp S. The level of serotonin in the superficial masseter muscle in relation to local pain and allodynia. Life Sci 1999;65:313-325.
13. Rosendal L, Larsson B, Kristiansen J, et al. Increase in muscle nociceptive substances and anaerobic metabolism in patients with trapezius myalgia: Microdialysis in rest and during exercise. Pain 2004;112:324-334.
14. Babenko V, Graven-Nielsen T, Svensson P, Drewes AM, Jensen TS, Arendt-Nielsen L. Experimental human muscle pain and muscular hyperalgesia induced by combinations of serotonin and bradykinin. Pain 1999;82:1-8.
15. Ernberg M, Lundeberg T, Kopp S. Pain and allodynia/hyperalgesia induced by intramuscular injection of serotonin in patients with fibromyalgia and healthy individuals. Pain 2000;85:31-39.
16. Ernberg M, Lundeberg T, Kopp S. Effect of propranolol and granisetron on experimentally induced pain and allodynia/hyperalgesia by intramuscular injection of serotonin into the human masseter muscle. Pain 2000;84:339-345.
17. Clark AD, Youd JM, Rattigan S, Barrett EJ, Clark MG. Heterogeneity of laser Doppler flowmetry in perfused muscle indicative of nutritive and nonnutritive flow. Am J Physiol Heart Circ Physiol 2001;280:H1324-H1333.
18. Alsip NL, Harris PD. Receptor mediation of microvascular responses to serotonin in striated muscle. Am J Physiol 1991;261:H1525-H1533.
19. Alsip NL, Harris PD. Serotonin-induced dilation of small arterioles is not mediated via endothelium-derived relaxing factor in skeletal muscle. Eur J Pharm 1992;229:117-124.
20. Kurita H, Ernberg M, Tominaga K, Alstergren P, Kopp S. Effect of 5-hydroxytryptamine infusion on microcirculation in the rabbit masseter muscle measured by laser-Doppler flowmetry and intramuscular temperature. Arch Oral Biol 1999;44:377-382.
21. Kurita H, Ernberg M, Tominaga K, Alstergren P, Kopp S. Effect of 5-hydroxytryptamine-2 and β-adrenergic receptor antagonists on 5-hydroxytryptamine-induced decrease in rabbit masseter muscle blood flow. Arch Oral Biol 1999;44:651-656.
22. Blauw G, Bom AH, van Brummelen P, et al. Effects of 5-hydroxytryptamine on capillary and arteriovenous anastomotic blood flow in the human hand and forearm and in the pig hind leg. J Cardiovasc Pharmacol 1991;17:316-324.
23. Borg G, Holmgren A, Lindblad I. Quantitative evaluation of chest pain. Acta Med Scand 1981;644(suppl):43-45.
24. Tullberg M, Alstergren PJ, Ernberg MM. Effects of low-power laser exposure on masseter muscle pain and microcirculation. Pain 2003;105:89-96.
25. Hedenberg-Magnusson B, Ernberg M, Kopp S. Symptoms and signs of temporomandibular disorders in patients with fibromyalgia and local myalgia of the temporomandibular system. A comparative study. Acta Odontol Scand 1997;55:344-349.
26. Jansen I, Olesen J, Edvinsson L. 5-Hydroxytryptamine receptor characterization of human cerebral, middle meningeal and temporal arteries: Regional differences. Acta Physiol Scand 1993;147:141-150.
27. Maekawa K, Clark GT, Kuboki T. Intramuscular hypoperfusion, adrenergic receptors, and chronic muscle pain. J Pain 2002;3:251-260.