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Volumn 11, Issue 1, 2015, Pages 144-149

Depression and cerebrovascular disease: Could vortioxetine represent a valid treatment option?

Author keywords

Cerebrovascular disease; Major depressive disorders; Vascular depression; Vortioxetine

Indexed keywords

PLACEBO; VORTIOXETINE;

EID: 84928661838     PISSN: None     EISSN: 17450179     Source Type: Journal    
DOI: 10.2174/1745017901511010144     Document Type: Article
Times cited : (11)

References (77)
  • 1
    • 84866739068 scopus 로고    scopus 로고
    • Cardiovascular disease in the developing world prevalences, patterns, and the potential of early disease detection
    • Celermajer DS, Chow CK, Marijon E, Anstey NM, Woo KS. Cardiovascular disease in the developing world prevalences, patterns, and the potential of early disease detection. J Am Coll Cardiol 2012; 60(14): 1207-16.
    • (2012) J Am Coll Cardiol , vol.60 , Issue.14 , pp. 1207-1216
    • Celermajer, D.S.1    Chow, C.K.2    Marijon, E.3    Anstey, N.M.4    Woo, K.S.5
  • 2
    • 79961106923 scopus 로고    scopus 로고
    • ASA/ACCF/AHA/AANN/ AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/ SNIS/SVM/SVS guideline on the management of patients with extracranial carotid and vertebral artery disease
    • [Epub 2011/02/02]
    • Brott TG, Halperin JL, Abbara S, et al. ASA/ACCF/AHA/AANN/ AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/ SNIS/SVM/SVS guideline on the management of patients with extracranial carotid and vertebral artery disease. Circulation 2011; 124(4): E54-130. [Epub 2011/02/02].
    • (2011) Circulation , vol.124 , Issue.4 , pp. e54-e130
    • Brott, T.G.1    Halperin, J.L.2    Abbara, S.3
  • 3
    • 77649091020 scopus 로고    scopus 로고
    • Executive summary: Heart disease and stroke statistics-2010 update: A report from the American Heart Association
    • Lloyd-Jones D, Adams RJ, Brown TM, et al. Executive summary: Heart disease and stroke statistics-2010 update: A report from the American Heart Association. Circulation 2010; 121(7): 948-54.
    • (2010) Circulation , vol.121 , Issue.7 , pp. 948-954
    • Lloyd-Jones, D.1    Adams, R.J.2    Brown, T.M.3
  • 4
    • 84867576446 scopus 로고    scopus 로고
    • Impaired cognitive function in patients with atherosclerotic carotid stenosis and correlation with ultrasound strain measurements
    • [Epub 2012 Jun 1]
    • Rocque BG, Jackson D, Varghese T, et al. Impaired cognitive function in patients with atherosclerotic carotid stenosis and correlation with ultrasound strain measurements. J Neurol Sci 2012; 322(1-2): 20-4. doi: 10.1016/j.jns.2012.05.020. [Epub 2012 Jun 1].
    • (2012) J Neurol Sci , vol.322 , Issue.1-2 , pp. 20-24
    • Rocque, B.G.1    Jackson, D.2    Varghese, T.3
  • 5
    • 84905961291 scopus 로고    scopus 로고
    • Prediction of asymptomatic carotid artery stenosis in the general population: Identification of high-risk groups
    • de Weerd M, Greving JP, Hedblad B, et al. Prediction of asymptomatic carotid artery stenosis in the general population: Identification of high-risk groups. Stroke 2014; 45(8): 2366-71.
    • (2014) Stroke , vol.45 , Issue.8 , pp. 2366-2371
    • De Weerd, M.1    Greving, J.P.2    Hedblad, B.3
  • 6
    • 33745927711 scopus 로고    scopus 로고
    • Treatment of depression in patients with coronary heart disease
    • Vieweg WV, Julius DA, Fernandez A, et al. Treatment of depression in patients with coronary heart disease. Am J Med 2006; 119(7): 567-73.
    • (2006) Am J Med , vol.119 , Issue.7 , pp. 567-573
    • Vieweg, W.V.1    Julius, D.A.2    Fernandez, A.3
  • 7
    • 34548396844 scopus 로고    scopus 로고
    • Depression, chronic diseases [no virgola] and decrements in health: Results from the World Health Surveys
    • Moussavi S, Chatterji S, Verdes E, Tandon A, Patel V, Ustun B. Depression, chronic diseases [no virgola] and decrements in health: Results from the World Health Surveys. Lancet 2007; 370: 851-8.
    • (2007) Lancet , vol.370 , pp. 851-858
    • Moussavi, S.1    Chatterji, S.2    Verdes, E.3    Tandon, A.4    Patel, V.5    Ustun, B.6
  • 8
    • 34548654401 scopus 로고    scopus 로고
    • Major depression in individuals with chronic medical disorders: Prevalence, correlates and association with health resource utilization, lost productivity and functional disability
    • Egede LE. Major depression in individuals with chronic medical disorders: Prevalence, correlates and association with health resource utilization, lost productivity and functional disability. Gen Hosp Psychiatry 2007; 29: 409-16.
    • (2007) Gen Hosp Psychiatry , vol.29 , pp. 409-416
    • Egede, L.E.1
  • 9
    • 33750156927 scopus 로고    scopus 로고
    • The prevalence of co-morbid depression in adults with Type 2 diabetes: A systematic review and meta-analysis
    • Ali S, Stone MA, Peters JL, Davies MJ, Khunti K. The prevalence of co-morbid depression in adults with Type 2 diabetes: A systematic review and meta-analysis. Diabet Med 2006; 23: 1165-73.
    • (2006) Diabet Med , vol.23 , pp. 1165-1173
    • Ali, S.1    Stone, M.A.2    Peters, J.L.3    Davies, M.J.4    Khunti, K.5
  • 10
    • 60949109909 scopus 로고    scopus 로고
    • Poststroke depression and functional outcome: A critical review of literature
    • Hadidi N, Treat-Jacobson DJ, Lindquist R. Poststroke depression and functional outcome: A critical review of literature. Hear Lung 2009; 38: 151-62.
    • (2009) Hear Lung , vol.38 , pp. 151-162
    • Hadidi, N.1    Treat-Jacobson, D.J.2    Lindquist, R.3
  • 12
    • 57049134256 scopus 로고    scopus 로고
    • Depressive symptoms, health behaviors, and risk of cardiovascular events in patients with coronary heart disease
    • Whooley MA, De JP, Vittinghoff E, et al. Depressive symptoms, health behaviors, and risk of cardiovascular events in patients with coronary heart disease. JAMA 2008; 300: 2379-88.
    • (2008) JAMA , vol.300 , pp. 2379-2388
    • Whooley, M.A.1    De, J.P.2    Vittinghoff, E.3
  • 13
    • 0036142074 scopus 로고    scopus 로고
    • Clinical presentation of the depression-executive dysfunction syndrome of late life
    • Alexopoulos GS, Kiosses DN, Klimstra S, et al. Clinical presentation of the "depression-executive dysfunction syndrome" of late life. Am J Geriatr Psychiatry 2002; 10: 98-106.
    • (2002) Am J Geriatr Psychiatry , vol.10 , pp. 98-106
    • Alexopoulos, G.S.1    Kiosses, D.N.2    Klimstra, S.3
  • 15
    • 0036842532 scopus 로고    scopus 로고
    • Frontal white matter microstructure and treatment response of late-life depression: A preliminary study
    • Alexopoulos GS, Kiosses DN, Choi SJ, et al. Frontal white matter microstructure and treatment response of late-life depression: A preliminary study. Am J Psychiatry 2002; 159: 1929-32.
    • (2002) Am J Psychiatry , vol.159 , pp. 1929-1932
    • Alexopoulos, G.S.1    Kiosses, D.N.2    Choi, S.J.3
  • 16
    • 1042300981 scopus 로고    scopus 로고
    • Clinical characteristics of magnetic resonance imaging-defined subcortical ischemic depression
    • Krishnan KR, Taylor WD, McQuoid DR, et al. Clinical characteristics of magnetic resonance imaging-defined subcortical ischemic depression. Biological Psychiatry 2004; 55:390-7.
    • (2004) Biological Psychiatry , vol.55 , pp. 390-397
    • Krishnan, K.R.1    Taylor, W.D.2    McQuoid, D.R.3
  • 17
    • 78349241786 scopus 로고    scopus 로고
    • Linking molecules to mood: New insight into the biology of depression
    • Krishnan V, Nestler EJ. Linking molecules to mood: New insight into the biology of depression. Am J Psychiatry 2010; 167: 1305-20.
    • (2010) Am J Psychiatry , vol.167 , pp. 1305-1320
    • Krishnan, V.1    Nestler, E.J.2
  • 18
    • 75149167066 scopus 로고    scopus 로고
    • Antidepressant medication and executive dysfunction: A deleterious interaction in late-life depression
    • Sneed JR, Culang ME, Keilp JG, et al. Antidepressant medication and executive dysfunction: A deleterious interaction in late-life depression. Am J Geriatr Psychiatry 2010; 18: 128-35.
    • (2010) Am J Geriatr Psychiatry , vol.18 , pp. 128-135
    • Sneed, J.R.1    Culang, M.E.2    Keilp, J.G.3
  • 19
    • 79551502956 scopus 로고    scopus 로고
    • The role of vascular risk factors in the development of DED syndrome among an elderly community sample
    • Kim BS, Lee DH, Lee DW, et al. The role of vascular risk factors in the development of DED syndrome among an elderly community sample. Am J Geriatr Psychiatry 2011; 19(2): 104-14. doi: 10.1097/JGP.0b013e31820119b6.
    • (2011) Am J Geriatr Psychiatry , vol.19 , Issue.2 , pp. 104-114
    • Kim, B.S.1    Lee, D.H.2    Lee, D.W.3
  • 20
    • 84911474148 scopus 로고    scopus 로고
    • Vascular cognitive disorders and depression after first-ever stroke: The fogarty-Mexico stroke cohort
    • [Epub ahead of print]
    • Arauz A, Rodríguez-Agudelo Y, Sosa AL, et al. Vascular cognitive disorders and depression after first-ever stroke: The fogarty-Mexico stroke cohort. Cerebrovasc Dis 2014; 38(4): 284-9. [Epub ahead of print]
    • (2014) Cerebrovasc Dis , vol.38 , Issue.4 , pp. 284-289
    • Arauz, A.1    Rodríguez-Agudelo, Y.2    Sosa, A.L.3
  • 21
    • 36048958879 scopus 로고    scopus 로고
    • Orbitofrontal cortex volume in late life depression: Influence of hyperintense lesions and genetic polymorphisms
    • Taylor WD, MacFall JR, Payne ME, et al. Orbitofrontal cortex volume in late life depression: Influence of hyperintense lesions and genetic polymorphisms. Psychol Med 2007; 37: 1763-73.
    • (2007) Psychol Med , vol.37 , pp. 1763-1773
    • Taylor, W.D.1    MacFall, J.R.2    Payne, M.E.3
  • 22
    • 4344590533 scopus 로고    scopus 로고
    • Neuroanatomical localization and clinical correlates of white matter lesions in the elderly
    • Artero S, Tiemeier H, Prins ND, et al. Neuroanatomical localization and clinical correlates of white matter lesions in the elderly. J Neurol Neurosurg 2004; 75: 1304-8.
    • (2004) J Neurol Neurosurg , vol.75 , pp. 1304-1308
    • Artero, S.1    Tiemeier, H.2    Prins, N.D.3
  • 23
    • 23644453791 scopus 로고    scopus 로고
    • Prominent reduction in pyramidal neurons density in the orbitofrontal cortex of elderly depressed patients
    • Rajkowska G, Miguel-Hidalgo JJ, Dubey P, et al. Prominent reduction in pyramidal neurons density in the orbitofrontal cortex of elderly depressed patients. Biological Psychiatry 2005; 58: 297-306.
    • (2005) Biological Psychiatry , vol.58 , pp. 297-306
    • Rajkowska, G.1    Miguel-Hidalgo, J.J.2    Dubey, P.3
  • 24
    • 79551473590 scopus 로고    scopus 로고
    • Morphometric analysis of neuronal and glial cell pathology in the caudate nucleus in late-life depression
    • Khundakar A, Morris C, Oakley A, Thomas AJ. Morphometric analysis of neuronal and glial cell pathology in the caudate nucleus in late-life depression. Am J Geriatr Psychiatry 2011; 19(2): 132-41.
    • (2011) Am J Geriatr Psychiatry , vol.19 , Issue.2 , pp. 132-141
    • Khundakar, A.1    Morris, C.2    Oakley, A.3    Thomas, A.J.4
  • 25
    • 84928686899 scopus 로고    scopus 로고
    • Oxidative stress and post-stroke depression: Possible therapeutic role of polyphenols?
    • Nabavi SF, Dean OM, Turner A, Sureda A, Daglia M, Nabavi SM. Oxidative stress and post-stroke depression: Possible therapeutic role of polyphenols? Curr Med Chem 2015; 22(3): 343-51.
    • (2015) Curr Med Chem , vol.22 , Issue.3 , pp. 343-351
    • Nabavi, S.F.1    Dean, O.M.2    Turner, A.3    Sureda, A.4    Daglia, M.5    Nabavi, S.M.6
  • 26
    • 84921489176 scopus 로고    scopus 로고
    • Neuroprotective effect of bone marrow stromal cell combination with atorvastatin in rat model of spinal cord injury
    • Li F, Fei D, Sun L, et al. Neuroprotective effect of bone marrow stromal cell combination with atorvastatin in rat model of spinal cord injury. Int J Clin Exp Med 2014; 7(12): 4967-74.
    • (2014) Int J Clin Exp Med , vol.7 , Issue.12 , pp. 4967-4974
    • Li, F.1    Fei, D.2    Sun, L.3
  • 27
    • 79955821239 scopus 로고    scopus 로고
    • Efficacy and tolerability of antidepressants in the treatment of behavioral and psychological symptoms of dementia, a literature review of evidence
    • Henry G, Williamson D, Tampi RR. Efficacy and tolerability of antidepressants in the treatment of behavioral and psychological symptoms of dementia, a literature review of evidence. Am J Alzheimers Dis Other Demen 2011; 26(3): 169-83. doi: 10.1177/ 1533317511402051.
    • (2011) Am J Alzheimers Dis Other Demen , vol.26 , Issue.3 , pp. 169-483
    • Henry, G.1    Williamson, D.2    Tampi, R.R.3
  • 28
    • 78650088616 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors provide significant lower re-hospitalization rates in patients recovering from acute coronary syndromes: Evidence from a meta-analysis
    • Mazza M, Lotrionte M, Biondi-Zoccai G, Abbate A, Sheiban I, Romagnoli E. Selective serotonin reuptake inhibitors provide significant lower re-hospitalization rates in patients recovering from acute coronary syndromes: Evidence from a meta-analysis. J Psychopharmacol 2010; 24: 1785-92.
    • (2010) J Psychopharmacol , vol.24 , pp. 1785-1792
    • Mazza, M.1    Lotrionte, M.2    Biondi-Zoccai, G.3    Abbate, A.4    Sheiban, I.5    Romagnoli, E.6
  • 29
    • 79952758182 scopus 로고    scopus 로고
    • Meta-analysis of selective serotonin reuptake inhibitors in patients with depression and coronary heart disease
    • Pizzi C, Rutjes AW, Costa GM, Fontana F, Mezzetti A, Manzoli L. Meta-analysis of selective serotonin reuptake inhibitors in patients with depression and coronary heart disease. Am J Cardiol 2011; 107: 972-9.
    • (2011) Am J Cardiol , vol.107 , pp. 972-979
    • Pizzi, C.1    Rutjes, A.W.2    Costa, G.M.3    Fontana, F.4    Mezzetti, A.5    Manzoli, L.6
  • 30
    • 84896040742 scopus 로고    scopus 로고
    • Effects of fluoxetine on brain-derived neurotrophic factor serum concentration and cognition in patients with vascular dementia
    • Liu X, Zhang J, Sun D, Fan Y, Zhou H, Fu B. Effects of fluoxetine on brain-derived neurotrophic factor serum concentration and cognition in patients with vascular dementia. Clin Interv Aging 2014; 9: 411-8. doi: 10.2147/CIA.S58830.
    • (2014) Clin Interv Aging , vol.9 , pp. 411-418
    • Liu, X.1    Zhang, J.2    Sun, D.3    Fan, Y.4    Zhou, H.5    Fu, B.6
  • 31
    • 0035433159 scopus 로고    scopus 로고
    • Vascular depression
    • Kurumatani T, Takeda M. Vascular depression. Nihon Rinsho 2001; 59(8): 1574-7.
    • (2001) Nihon Rinsho , vol.59 , Issue.8 , pp. 1574-1577
    • Kurumatani, T.1    Takeda, M.2
  • 33
    • 67650345357 scopus 로고    scopus 로고
    • Acute massive gastrointestinal bleeding in the elderly
    • Kimura A, Iwamoto T. Acute massive gastrointestinal bleeding in the elderly. Nihon Ronen Igakkai Zasshi 2009; 46(3): 250-8.
    • (2009) Nihon Ronen Igakkai Zasshi , vol.46 , Issue.3 , pp. 250-258
    • Kimura, A.1    Iwamoto, T.2
  • 35
    • 84879596410 scopus 로고    scopus 로고
    • Serotonin reuptake inhibitor use depression and long-term outcomes after an acute coronary syndrome: A prospective cohort study
    • Rieckmann N, Kronish IM, Shapiro PA, Whang W, Davidson KW. Serotonin reuptake inhibitor use, depression, and long-term outcomes after an acute coronary syndrome: A prospective cohort study. JAMA Intern Med 2013; 173(12): 1150-1. doi: 10.1001/ jamainternmed. 2013.910.
    • (2013) JAMA Intern Med , vol.173 , Issue.12 , pp. 1150-1151
    • Rieckmann, N.1    Kronish, I.M.2    Shapiro, P.A.3    Whang, W.4    Davidson, K.W.5
  • 36
    • 84857921759 scopus 로고    scopus 로고
    • Is electroconvulsive therapy (ECT) effective and safe for treatment of depression in dementia? A short review
    • Oudman E. Is electroconvulsive therapy (ECT) effective and safe for treatment of depression in dementia? A short review. J ECT 2012; 28(1): 34-8.
    • (2012) J ECT , vol.28 , Issue.1 , pp. 34-38
    • Oudman, E.1
  • 37
    • 0037235976 scopus 로고    scopus 로고
    • Problem-solving therapy versus supportive therapy in geriatric major depression with executive dysfunction
    • Alexopoulos GS, Raue P, Arean P. Problem-solving therapy versus supportive therapy in geriatric major depression with executive dysfunction. Am J Geriatr Psychiat 2003; 11: 46-52.
    • (2003) Am J Geriatr Psychiat , vol.11 , pp. 46-52
    • Alexopoulos, G.S.1    Raue, P.2    Arean, P.3
  • 38
    • 78149283788 scopus 로고    scopus 로고
    • Home-delivered problem adaptation therapy (PATH) for depressed, cognitively impaired, disabled elders: A preliminary study
    • Kiosses DN, Arean PA, Teri L, Alexopoulos GS. Home-delivered problem adaptation therapy (PATH) for depressed, cognitively impaired, disabled elders: A preliminary study. Am J Geriatr Psychiatry 2010; 18(11): 988-98. doi: 10.1097/JGP.0b013e3181d6947d
    • (2010) Am J Geriatr Psychiatry , vol.18 , Issue.11 , pp. 988-998
    • Kiosses, D.N.1    Arean, P.A.2    Teri, L.3    Alexopoulos, G.S.4
  • 39
    • 84908894271 scopus 로고    scopus 로고
    • Cognition in late life depression: Treatment considerations
    • Koenig AM, Butters MA. Cognition in late life depression: Treatment considerations. Curr Treat Options Psychiatry 2014; 1(1): 1-14.
    • (2014) Curr Treat Options Psychiatry , vol.1 , Issue.1 , pp. 1-14
    • Koenig, A.M.1    Butters, M.A.2
  • 40
    • 84876108581 scopus 로고    scopus 로고
    • In vitro and in vivo effects of the multimodal antidepressant vortioxetine (Lu AA21004) at human and rat targets
    • Westrich L, Pehrson A, Zhong H, et al. In vitro and in vivo effects of the multimodal antidepressant vortioxetine (Lu AA21004) at human and rat targets. Int J Psychiatr Clin Pract 2012; 16(Suppl 1): 47.
    • (2012) Int J Psychiatr Clin Pract , vol.16 , pp. 47
    • Westrich, L.1    Pehrson, A.2    Zhong, H.3
  • 41
    • 84863403855 scopus 로고    scopus 로고
    • Pharmacological effects of Lu AA21004: A novel multimodal compound for the treatment of major depressive disorder
    • Mørk A, Pehrson A, Brennum LT, et al. Pharmacological effects of Lu AA21004: A novel multimodal compound for the treatment of major depressive disorder. J Pharmacol Exp Ther 2012; 340(3): 666-75.
    • (2012) J Pharmacol Exp Ther , vol.340 , Issue.3 , pp. 666-675
    • Mørk, A.1    Pehrson, A.2    Brennum, L.T.3
  • 42
    • 84873523331 scopus 로고    scopus 로고
    • Lu AA21004 a novel multimodal antidepressant produces regionally selective increases of multiple neurotransmitters - A rat microdialysis and electrophysiology study
    • Pehrson AL, Cremers T, Bétry C, et al. Lu AA21004, a novel multimodal antidepressant, produces regionally selective increases of multiple neurotransmitters - a rat microdialysis and electrophysiology study. Eur Neuropsychopharmacol 2013; 23(2): 133-45.
    • (2013) Eur Neuropsychopharmacol , vol.23 , Issue.2 , pp. 133-145
    • Pehrson, A.L.1    Cremers, T.2    Bétry, C.3
  • 43
    • 84872347531 scopus 로고    scopus 로고
    • Serotonin receptors involved in antidepressant effects
    • Artigas F. Serotonin receptors involved in antidepressant effects. Pharmacol Ther 2013; 137(1):119-31.
    • (2013) Pharmacol Ther , vol.137 , Issue.1 , pp. 119-131
    • Artigas, F.1
  • 44
    • 0030247182 scopus 로고    scopus 로고
    • Acceleration of the effect of selected antidepressant drugs in major depression by 5- HT1A antagonists
    • Artigas F, Romero L, de Montigny C, Blier P. Acceleration of the effect of selected antidepressant drugs in major depression by 5- HT1A antagonists. Trends Neurosci 1996; 19(9): 378-83.
    • (1996) Trends Neurosci , vol.19 , Issue.9 , pp. 378-383
    • Artigas, F.1    Romero, L.2    De Montigny, C.3    Blier, P.4
  • 45
    • 84901720404 scopus 로고    scopus 로고
    • Serotonergic modulation of glutamate neurotransmission as a strategy for treating depression and cognitive dysfunction
    • [Epub 2013 Aug 1]
    • Pehrson AL, Sanchez C. Serotonergic modulation of glutamate neurotransmission as a strategy for treating depression and cognitive dysfunction. CNS Spectr 2014; 19(2): 121-33. doi: 10.1017/ S1092852913000540. [Epub 2013 Aug 1].
    • (2014) CNS Spectr , vol.19 , Issue.2 , pp. 121-433
    • Pehrson, A.L.1    Sanchez, C.2
  • 46
    • 84907506717 scopus 로고    scopus 로고
    • Vortioxetine disinhibits pyramidal cell function and enhances synaptic plasticity in the rat hippo campus
    • Dale E, Zhang H, Leiser SC, et al. Vortioxetine disinhibits pyramidal cell function and enhances synaptic plasticity in the rat hippo campus. J Psychopharmacol 2014; 28(10): 891-902. doi: 10.1177/ 0269881114543719.
    • (2014) J Psychopharmacol , vol.28 , Issue.10 , pp. 891-902
    • Dale, E.1    Zhang, H.2    Leiser, S.C.3
  • 47
    • 84904425500 scopus 로고    scopus 로고
    • Pharmacology and clinical potential of vortioxetine in the treatment of major depressive disorder
    • Alvarez E, Perez V, Artigas F. Pharmacology and clinical potential of vortioxetine in the treatment of major depressive disorder. Neuropsychiatr Dis Treat 2014; 10: 1297-307. doi: 10.2147/ NDT.S41387.
    • (2014) Neuropsychiatr Dis Treat , vol.10 , pp. 1297-1307
    • Alvarez, E.1    Perez, V.2    Artigas, F.3
  • 48
    • 84862698575 scopus 로고    scopus 로고
    • Identification of the cytochrome P450 and other enzymes involved in the in vitro oxidative metabolism of a novel antidepressant, Lu AA21004
    • Hvenegaard MG, Bang-Andersen B, Pedersen H, Jørgensen M, Püschl A, Dalgaard L. Identification of the cytochrome P450 and other enzymes involved in the in vitro oxidative metabolism of a novel antidepressant, Lu AA21004. Drug Metab Dispos 2012; 40(7): 1357-65.
    • (2012) Drug Metab Dispos , vol.40 , Issue.7 , pp. 1357-1365
    • Hvenegaard, M.G.1    Bang-Andersen, B.2    Pedersen, H.3    Jørgensen, M.4    Püschl, A.5    Dalgaard, L.6
  • 49
    • 84928661308 scopus 로고    scopus 로고
    • Wnt signaling in neuropsychiatric disorders: Ties with adult hippocampal neurogenesis and behavior
    • [Epub 2014 Sep 28]
    • Hussaini SM, Choi CI, Cho CH, Kim HJ, Jun H, Jang MH. Wnt signaling in neuropsychiatric disorders: Ties with adult hippocampal neurogenesis and behavior. Neurosci Biobehav Rev 2014; 47: 369-83. doi: 10.1016/j.neubiorev.2014.09.005. [Epub 2014 Sep 28].
    • (2014) Neurosci Biobehav Rev , vol.47 , pp. 369-383
    • Hussaini, S.M.1    Choi, C.I.2    Cho, C.H.3    Kim, H.J.4    Jun, H.5    Jang, M.H.6
  • 50
    • 84891863666 scopus 로고    scopus 로고
    • The risk of Bipolar Disorders in Multiple Sclerosis
    • Carta MG, Moro MF, Lorefice L, et al. The risk of Bipolar Disorders in Multiple Sclerosis. J Affect Disord 2014; 155: 255-60. doi: 10.1016/j.jad.2013.11.008.
    • (2014) J Affect Disord , vol.155 , pp. 255-260
    • Carta, M.G.1    Moro, M.F.2    Lorefice, L.3
  • 51
    • 84871132137 scopus 로고    scopus 로고
    • GABAergic neuroactive steroids: A new frontier in bipolar disorders?
    • Carta MG, Bhat KM, Preti A. GABAergic neuroactive steroids: A new frontier in bipolar disorders? Behav Brain Funct 2012; 8(1): 61.
    • (2012) Behav Brain Funct , vol.8 , Issue.1 , pp. 61
    • Carta, M.G.1    Bhat, K.M.2    Preti, A.3
  • 52
    • 84861552863 scopus 로고    scopus 로고
    • Bipolar disorders and Wilson's disease
    • Carta MG, Sorbello O, Moro MF, et al. Bipolar disorders and Wilson's disease. BMC Psychiatry 2012; 12(1): 52.
    • (2012) BMC Psychiatry , vol.12 , Issue.1 , pp. 52
    • Carta, M.G.1    Sorbello, O.2    Moro, M.F.3
  • 53
    • 33746891173 scopus 로고    scopus 로고
    • Increased neuroactive steroid concentrations in women with bipolar disorder or major depressive disorder
    • Hardoy MC, Serra M, Carta MG, Contu P, Pisu MG, Biggio G. Increased neuroactive steroid concentrations in women with bipolar disorder or major depressive disorder. J Clin Psychopharmacol 2006; 26(4): 379-84.
    • (2006) J Clin Psychopharmacol , vol.26 , Issue.4 , pp. 379-384
    • Hardoy, M.C.1    Serra, M.2    Carta, M.G.3    Contu, P.4    Pisu, M.G.5    Biggio, G.6
  • 54
    • 58149328474 scopus 로고    scopus 로고
    • The immediate early gene arc/arg3.1: Regulation, mechanisms, and function
    • Bramham CR, Worley PF, Moore MJ, Guzowski JF. The immediate early gene arc/arg3.1: Regulation, mechanisms, and function. J Neurosci 2008; 28: 11760-7.
    • (2008) J Neurosci , vol.28 , pp. 11760-11767
    • Bramham, C.R.1    Worley, P.F.2    Moore, M.J.3    Guzowski, J.F.4
  • 55
    • 0034213297 scopus 로고    scopus 로고
    • Inhibition of activity- dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory
    • Guzowski JF, Lyford GL, Stevenson GD, et al. Inhibition of activity- dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory. J Neurosci 2000; 20: 3993-4001.
    • (2000) J Neurosci , vol.20 , pp. 3993-4001
    • Guzowski, J.F.1    Lyford, G.L.2    Stevenson, G.D.3
  • 56
    • 84877004426 scopus 로고    scopus 로고
    • Effects of lurasidone in behavior models of depression. Role of the 5-HT receptor subtype
    • Cates LN, Roberts AJ, Huitron-Resendiz S, Hedlund PB. Effects of lurasidone in behavior models of depression. Role of the 5-HT receptor subtype. Neuropharmacology 2013; 70C: 211-7.
    • (2013) Neuropharmacology , vol.70 C , pp. 211-217
    • Cates, L.N.1    Roberts, A.J.2    Huitron-Resendiz, S.3    Hedlund, P.B.4
  • 57
    • 33845741592 scopus 로고    scopus 로고
    • Enhancement of the anti-immobility action of antidepressants by a selective 5-HT7 receptor antagonist in the forced swimming test in mice
    • Wesolowska A, Tatarczynska E, Nikiforuk A, Chojnacka-Wojcik E. Enhancement of the anti-immobility action of antidepressants by a selective 5-HT7 receptor antagonist in the forced swimming test in mice. Eur J Pharmacol 2007; 555: 43-7.
    • (2007) Eur J Pharmacol , vol.555 , pp. 43-47
    • Wesolowska, A.1    Tatarczynska, E.2    Nikiforuk, A.3    Chojnacka-Wojcik, E.4
  • 58
    • 84858753620 scopus 로고    scopus 로고
    • The 5-HT(7) receptor in learning and memory
    • Roberts AJ, Hedlund PB. The 5-HT(7) receptor in learning and memory. Hippocampus 2012; 22: 762-71.
    • (2012) Hippocampus , vol.22 , pp. 762-771
    • Roberts, A.J.1    Hedlund, P.B.2
  • 59
    • 84885163818 scopus 로고    scopus 로고
    • Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice
    • [Epub 2013 May 28]
    • Guilloux JP, Mendez-David I, Pehrson A, et al. Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice. Neuropharmacology 2013; 73: 147-59. doi: 10.1016/ j.neuropharm.2013.05.014. [Epub 2013 May 28].
    • (2013) Neuropharmacology , vol.73 , pp. 147-159
    • Guilloux, J.P.1    Mendez-David, I.2    Pehrson, A.3
  • 60
    • 84928208045 scopus 로고    scopus 로고
    • Vortioxetine: A meta-analysis of 12 short-term, randomized, placebo-controlled clinical trials for the treatment of major depressive disorder
    • [Epub ahead of print]
    • Pae CU, Wang SM, Han C, et al. Vortioxetine: A meta-analysis of 12 short-term, randomized, placebo-controlled clinical trials for the treatment of major depressive disorder. J Psychiatry Neurosci. 2014; 39(6): 140120. doi: 10.1503/jpn.140120. [Epub ahead of print]
    • (2014) J Psychiatry Neurosci , vol.39 , Issue.6 , pp. 140120
    • Pae, C.U.1    Wang, S.M.2    Han, C.3
  • 61
    • 84875933121 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled 6-wk trial of the efficacy and tolerability of 5 mg vortioxetine in adults with major depressive disorder
    • Jain R, Mahableshwarkar AR, Jacobsen PL, Chen Y, Thase ME. A randomized, double-blind, placebo-controlled 6-wk trial of the efficacy and tolerability of 5 mg vortioxetine in adults with major depressive disorder. Int J Neuropsychopharmacol 2013; 16(2): 313-21.
    • (2013) Int J Neuropsychopharmacol , vol.16 , Issue.2 , pp. 313-321
    • Jain, R.1    Mahableshwarkar, A.R.2    Jacobsen, P.L.3    Chen, Y.4    Thase, M.E.5
  • 62
    • 84861481738 scopus 로고    scopus 로고
    • A randomised, double-blind, placebo controlled, duloxetine-referenced, fixed-dose study of three dosages of Lu AA21004 in acute treatment of major depressive disorder (MDD)
    • Baldwin DS, Loft H, Dragheim M. A randomised, double-blind, placebo controlled, duloxetine-referenced, fixed-dose study of three dosages of Lu AA21004 in acute treatment of major depressive disorder (MDD). Eur Neuropsychopharmacol 2012; 22(7): 482-91.
    • (2012) Eur Neuropsychopharmacol , vol.22 , Issue.7 , pp. 482-491
    • Baldwin, D.S.1    Loft, H.2    Dragheim, M.3
  • 63
    • 84898476386 scopus 로고    scopus 로고
    • A duloxetine-referenced, fixed dose study comparing efficacy and safety of 2 vortioxetine doses in the acute treatment of adult MDD patients
    • Poster presented at San Francisco, CA, May
    • Mahableshwarkar AR, Jacobsen PL, Serenko M, Chen Y, Trivedi MH. A duloxetine-referenced, fixed dose study comparing efficacy and safety of 2 vortioxetine doses in the acute treatment of adult MDD patients; Poster presented at: American Psychiatry Association Annual Meeting; San Francisco, CA, May 18-22, 2013a.
    • (2013) American Psychiatry Association Annual Meeting , pp. 18-22
    • Mahableshwarkar, A.R.1    Jacobsen, P.L.2    Serenko, M.3    Chen, Y.4    Trivedi, M.H.5
  • 64
    • 84873618031 scopus 로고    scopus 로고
    • A randomized double- blind trial of 2.5 mg and 5 mg vortioxetine (Lu AA21004) versus placebo for 8 weeks in adults with major depressive disorder
    • Mahableshwarkar AR, Jacobsen PL, Chen Y. A randomized, double- blind trial of 2.5 mg and 5 mg vortioxetine (Lu AA21004) versus placebo for 8 weeks in adults with major depressive disorder. Curr Med Res Opin 2013b; 29(3): 217-26.
    • (2013) Curr Med Res Opin , vol.29 , Issue.3 , pp. 217-226
    • Mahableshwarkar, A.R.1    Jacobsen, P.L.2    Chen, Y.3
  • 65
    • 84898476386 scopus 로고    scopus 로고
    • A randomized double blind parallel placebo-controlled fixed-dose study comparing the efficacy and safety of 2 doses of vortioxetine (LU AA21004) in acute treatment of adults with major depressive disorder
    • Poster presented at San Francisco CA May
    • Mahableshwarkar AR, Jacobsen PL, Serenko M, Chen Y, Trivedi MH. A randomized, double blind, parallel, placebo-controlled, fixed-dose study comparing the efficacy and safety of 2 doses of vortioxetine (LU AA21004) in acute treatment of adults with major depressive disorder; Poster presented at: American Psychiatry Association Annual Meeting; San Francisco, CA, May 18-22, 2013c.
    • (2013) American Psychiatry Association Annual Meeting , pp. 18-22
    • Mahableshwarkar, A.R.1    Jacobsen, P.L.2    Serenko, M.3    Chen, Y.4    Trivedi, M.H.5
  • 66
    • 84899746962 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled study of the efficacy and safety of vortioxetine 10 mg and 20 mg in adults with Major Depressive Disorder
    • Poster presented at San Francisco, CA, May
    • Jacobsen PL, Mahableshwarkar AR, Serenko M, Chan S, Trivedi MH. A randomized, double-blind, placebo-controlled study of the efficacy and safety of vortioxetine 10 mg and 20 mg in adults with Major Depressive Disorder; Poster presented at: American Psychiatry Association Annual Meeting; San Francisco, CA, May 18-22, 2013a.
    • (2013) American Psychiatry Association Annual Meeting , pp. 18-22
    • Jacobsen, P.L.1    Mahableshwarkar, A.R.2    Serenko, M.3    Chan, S.4    Trivedi, M.H.5
  • 67
    • 84861065050 scopus 로고    scopus 로고
    • A doubleblind, randomized, placebo-controlled, active reference study of Lu AA21004 in patients with major depressive disorder
    • Alvarez E, Perez V, Dragheim M, Loft H, Artigas F. A doubleblind, randomized, placebo-controlled, active reference study of Lu AA21004 in patients with major depressive disorder. Int J Neuropsychopharmacol 2012; 15(5): 589-600.
    • (2012) Int J Neuropsychopharmacol , vol.15 , Issue.5 , pp. 589-600
    • Alvarez, E.1    Perez, V.2    Dragheim, M.3    Loft, H.4    Artigas, F.5
  • 68
    • 84864409459 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled 8-week trial of the efficacy and tolerability of multiple doses of Lu AA21004 in adults with major depressive disorder
    • Henigsberg N, Mahableshwarkar AR, Jacobsen P, Chen Y, Thase ME. A randomized, double-blind, placebo-controlled 8-week trial of the efficacy and tolerability of multiple doses of Lu AA21004 in adults with major depressive disorder. J Clin Psychiatry 2012; 73(7): 953-9.
    • (2012) J Clin Psychiatry , vol.73 , Issue.7 , pp. 953-959
    • Henigsberg, N.1    Mahableshwarkar, A.R.2    Jacobsen, P.3    Chen, Y.4    Thase, M.E.5
  • 69
    • 84862132965 scopus 로고    scopus 로고
    • A randomized double-blind placebo- controlled duloxetine-referenced fixed-dose study comparing the efficacy and safety of Lu AA21004 in elderly patients with major depressive disorder
    • Katona C, Hansen T, Olsen CK. A randomized, double-blind, placebo- controlled, duloxetine-referenced, fixed-dose study comparing the efficacy and safety of Lu AA21004 in elderly patients with major depressive disorder. Int Clin Psychopharmacol 2012; 27(4): 215-23.
    • (2012) Int Clin Psychopharmacol , vol.27 , Issue.4 , pp. 215-223
    • Katona, C.1    Hansen, T.2    Olsen, C.K.3
  • 70
    • 84897528985 scopus 로고    scopus 로고
    • Efficacy and safety of vortioxetine (Lu AA21004) 15 and 20 mg/day: A randomized double-blind placebo-controlled duloxetine-referenced study in the acute treatment of adult patients with major depressive disorder
    • Boulenger JP, Loft H, Olsen CK. Efficacy and safety of vortioxetine (Lu AA21004), 15 and 20 mg/day: A randomized, double-blind, placebo-controlled, duloxetine-referenced study in the acute treatment of adult patients with major depressive disorder. Int Clin Psychopharmacol 2014; 29(3): 138-49.
    • (2014) Int Clin Psychopharmacol , vol.29 , Issue.3 , pp. 138-149
    • Boulenger, J.P.1    Loft, H.2    Olsen, C.K.3
  • 71
    • 84898427083 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled study of the efficacy of vortioxetine on cognitive function in adult patients with major depressive disorder (MDD)
    • Poster presented at Hollywood, FL, December 8-12
    • McIntyre RS, Lophaven S, Olsen CK. Randomized, double-blind, placebo-controlled study of the efficacy of vortioxetine on cognitive function in adult patients with major depressive disorder (MDD); Poster presented at: 52nd Annual Meeting of the American College of Neuropsychopharmacology (ACNP); Hollywood, FL, December 8-12, 2013.
    • (2013) 52nd Annual Meeting of the American College of Neuropsychopharmacology (ACNP)
    • McIntyre, R.S.1    Lophaven, S.2    Olsen, C.K.3
  • 72
    • 84914135696 scopus 로고    scopus 로고
    • A randomised, double blind, active controlled study of vortioxetine (10-20 mg/day) versus agomelatine 25-50 mg/day) in adults with Major Depressive Disorder with inadequate response to antidepressant treatment
    • Poster presented at Barcelona, Spain, October 5-9
    • Häggström L, Nielsen RZ, Poulsen L, Danchenko N. A randomised, double blind, active controlled study of vortioxetine (10-20 mg/day) versus agomelatine 25-50 mg/day) in adults with Major Depressive Disorder with inadequate response to antidepressant treatment; Poster presented at: 26th Congress of the European College of Neuropsychopharmacology (ECNP); Barcelona, Spain, October 5-9, 2013.
    • (2013) 26th Congress of the European College of Neuropsychopharmacology (ECNP)
    • Häggström, L.1    Nielsen, R.Z.2    Poulsen, L.3    Danchenko, N.4
  • 74
    • 84928689956 scopus 로고    scopus 로고
    • A randomized double-blind study of vortioxetine versus agomelatine in adults with major depressive disorder (MDD) switched after inadequate response to SSRI or SNRI treatment (NCT01488071) [poster]
    • Hollywood FL May 28-31
    • Dragheim M, Nielsen RZ. A randomized, double-blind, study of vortioxetine versus agomelatine in adults with major depressive disorder (MDD) switched after inadequate response to SSRI or SNRI treatment (NCT01488071) [poster]. NCDEU 53rd Annual Meeting; Hollywood, FL, 2013 May 28-31.
    • (2013) NCDEU 53rd Annual Meeting
    • Dragheim, M.1    Nielsen, R.Z.2
  • 75
    • 84862131007 scopus 로고    scopus 로고
    • A randomized clinical study of Lu AA21004 in the prevention of relapse in patients with major depressive disorder
    • Boulenger JP, Loft H, Florea I. A randomized clinical study of Lu AA21004 in the prevention of relapse in patients with major depressive disorder. J Psychopharmacol 2012; 26(11): 1408-16.
    • (2012) J Psychopharmacol , vol.26 , Issue.11 , pp. 1408-1416
    • Boulenger, J.P.1    Loft, H.2    Florea, I.3
  • 76
    • 84892475914 scopus 로고    scopus 로고
    • Vortioxetine dose-dependently reverses 5-HT depletion-induced deficits in spatial working and object recognition memory: A potential role for 5- HT1A receptor agonism and 5-HT3 receptor antagonism
    • du Jardin KG, Jensen JB, Sanchez C, Pehrson AL. Vortioxetine dose-dependently reverses 5-HT depletion-induced deficits in spatial working and object recognition memory: A potential role for 5- HT1A receptor agonism and 5-HT3 receptor antagonism. Eur Neuropsychopharmacol 2014; 24(1): 160-71.
    • (2014) Eur Neuropsychopharmacol , vol.24 , Issue.1 , pp. 160-171
    • Du Jardin, K.G.1    Jensen, J.B.2    Sanchez, C.3    Pehrson, A.L.4
  • 77
    • 84878256637 scopus 로고    scopus 로고
    • A randomized trial on the acute and steady-state effects of a new antidepressant vortioxetine (Lu AA21004) on actual driving and cognition
    • Theunissen EL, Street D, Hojer AM, et al. A randomized trial on the acute and steady-state effects of a new antidepressant, vortioxetine (Lu AA21004), on actual driving and cognition. Clin Pharmacol Ther 2013; 93(6): 493-501.
    • (2013) Clin Pharmacol Ther , vol.93 , Issue.6 , pp. 493-501
    • Theunissen, E.L.1    Street, D.2    Hojer, A.M.3


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