메뉴 건너뛰기




Volumn 26, Issue 3, 2011, Pages 169-183

Efficacy and tolerability of antidepressants in the treatment of behavioral and psychological symptoms of dementia, a literature review of evidence

Author keywords

antidepressants; behavioral and psychological symptoms of dementia; dementia; selective serotonin reuptake inhibitors; trazodone

Indexed keywords

ANTIDEPRESSANT AGENT; CITALOPRAM; DONEPEZIL; FLUOXETINE; FLUVOXAMINE; HALOPERIDOL; PAROXETINE; PERPHENAZINE; PIRACETAM; PLACEBO; RISPERIDONE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TRAZODONE;

EID: 79955821239     PISSN: 15333175     EISSN: None     Source Type: Journal    
DOI: 10.1177/1533317511402051     Document Type: Review
Times cited : (78)

References (34)
  • 1
    • 0036900832 scopus 로고    scopus 로고
    • Managing behavioural and psychological symptoms in dementia
    • DOI 10.1192/bjp.181.6.463
    • Lawlor B. Managing behavioural and psychological symptoms in dementia. Br J Psychiatry. 2002 ; 181: 463-465. (Pubitemid 35440668)
    • (2002) British Journal of Psychiatry , vol.181 , Issue.DEC. , pp. 463-465
    • Lawlor, B.1
  • 2
    • 0038799857 scopus 로고    scopus 로고
    • Assessment of behavioral and psychological symptoms of dementia
    • Bharucha AJ, Rosen J., Mulsant BH, Pollock BG Assessment of behavioral and psychological symptoms of dementia. CNS Spectr. 2002 ; 7 (11). 797-802. (Pubitemid 36765054)
    • (2002) CNS Spectrums , vol.7 , Issue.11 , pp. 797-802
    • Bharucha, A.J.1    Rosen, J.2    Mulsant, B.H.3    Pollock, B.G.4
  • 5
    • 0036669270 scopus 로고    scopus 로고
    • Depression in Alzheimer's disease: Overview and treatment
    • DOI 10.1016/S0006-3223(02)01348-3, PII S0006322302013483
    • Lyketsos CG, Olin J. Depression in Alzheimer's disease: overview and treatment. Biol Psychiatry. 2002 ; 52 (3). 243-252. (Pubitemid 35232091)
    • (2002) Biological Psychiatry , vol.52 , Issue.3 , pp. 243-252
    • Lyketsos, C.G.1    Olin, J.2
  • 6
    • 0025345780 scopus 로고
    • Psychiatric phenomena in Alzheimer's disease. I: Disorders of thought content
    • Burns A., Jacoby R., Levy R. Psychiatric phenomena in Alzheimer's disease. I: Disorders of thought content. Br J Psychiatry. 1990 ; 157: 72-76 ; 92-94. (Pubitemid 20208663)
    • (1990) British Journal of Psychiatry , vol.157 , Issue.JULY , pp. 72-76
    • Burns, A.1    Jacoby, R.2    Levy, R.3
  • 7
    • 31544457597 scopus 로고    scopus 로고
    • Neurotransmitter deficits in behavioural and psychological symptoms of Alzheimer's disease
    • DOI 10.1016/j.mad.2005.09.016, PII S0047637405002344, Dementias and Cognitive Sidorders: New Insights and Approaches
    • Lanari A., Amenta F., Silvestrelli G., Tomassoni D., Parnetti L. Neurotransmitter deficits in behavioural and psychological symptoms of Alzheimer's disease. Mech Ageing Dev. 2006 ; 127 (2). 158-165. (Pubitemid 43165614)
    • (2006) Mechanisms of Ageing and Development , vol.127 , Issue.2 , pp. 158-165
    • Lanari, A.1    Amenta, F.2    Silvestrelli, G.3    Tomassoni, D.4    Parnetti, L.5
  • 8
    • 77956193823 scopus 로고    scopus 로고
    • Management of neuropsychiatric symptoms in people with dementia
    • Ballard C., Corbett A. Management of neuropsychiatric symptoms in people with dementia. CNS Drugs. 2010 ; 24 (9). 729-739.
    • (2010) CNS Drugs. , vol.24 , Issue.9 , pp. 729-739
    • Ballard, C.1    Corbett, A.2
  • 9
    • 0025244327 scopus 로고
    • The clinical efficacy of citalopram in treatment of emotional disturbances in dementia disorders. A Nordic multicentre study
    • Nyth AL, Gottfries CG The clinical efficacy of citalopram in treatment of emotional disturbances in dementia disorders. A Nordic multicentre study. Br J Psychiatry. 1990 ; 157: 894-901.
    • (1990) Br J Psychiatry , vol.157 , pp. 894-901
    • Nyth, A.L.1    Gottfries, C.G.2
  • 10
    • 0026750284 scopus 로고
    • Fluvoxamine in the treatment of demented elderly patients: A double-blind, placebo-controlled study
    • Olafsson K., Jørgensen S., Jensen HV, Bille A., Arup P., Andersen J. Fluvoxamine in the treatment of demented elderly patients: a double-blind, placebo-controlled study. Acta Psychiatr Scand. 1992 ; 85 (6). 453-456.
    • (1992) Acta Psychiatr Scand , vol.85 , Issue.6 , pp. 453-456
    • Olafsson, K.1    Jørgensen, S.2    Jensen, H.V.3    Bille, A.4    Arup, P.5    Andersen, J.6
  • 11
    • 0031474315 scopus 로고    scopus 로고
    • Pilot study of haloperidol, fluoxetine, and placebo for agitation in Alzheimer's disease
    • Auchus AP, Bissey-Black C. Pilot study of haloperidol, fluoxetine, and placebo for agitation in Alzheimer's disease. J Neuropsychiatry Clin Neurosci. 1997 ; 9 (4). 591-593. (Pubitemid 28029755)
    • (1997) Journal of Neuropsychiatry and Clinical Neurosciences , vol.9 , Issue.4 , pp. 591-593
    • Auchus, A.P.1    Bissey-Black, C.2
  • 12
    • 0033988108 scopus 로고    scopus 로고
    • A controlled clinical trial of sertraline in the treatment of depression in nursing home patients with late-stage Alzheimer's disease
    • Magai C., Kennedy G., Cohen CI, Gomberg D. A controlled clinical trial of sertraline in the treatment of depression in nursing home patients with late-stage Alzheimer's disease. Am J Geriatr Psychiatry. 2000 ; 8 (1). 66-74. (Pubitemid 30036843)
    • (2000) American Journal of Geriatric Psychiatry , vol.8 , Issue.1 , pp. 66-74
    • Magai, C.1    Kennedy, G.2    Cohen, C.I.3    Gomberg, D.4
  • 13
    • 0034903550 scopus 로고    scopus 로고
    • Sertraline versus small doses of haloperidol in the treatment of agitated behavior in patients with dementia
    • DOI 10.1016/S0167-4943(01)00135-2
    • Gaber S., Ronzoli S., Bruno A., Biagi A. Sertraline versus small doses of haloperidol in the treatment of agitated behavior in patients with dementia. Arch Gerontol Geriatr Suppl. 2001 ; 7: 159-162. (Pubitemid 32727480)
    • (2001) Archives of Gerontology and Geriatrics , vol.33 , Issue.SUPPL. , pp. 159-162
    • Gaber, S.1    Ronzoni, S.2    Bruno, A.3    Biagi, A.4
  • 14
    • 0036082096 scopus 로고    scopus 로고
    • Gender, aggression and serotonergic function are associated with response to sertraline for behavioral disturbances in Alzheimer's disease
    • DOI 10.1002/gps.636
    • Lanctôt KL, Herrmann N., van Reekum R., Eryavec G., Naranjo CA Gender, aggression and serotonergic function are associated with response to sertraline for behavioral disturbances in Alzheimer's disease. Int J Geriatr Psychiatry. 2002 ; 17 (6). 531-541. (Pubitemid 34678705)
    • (2002) International Journal of Geriatric Psychiatry , vol.17 , Issue.6 , pp. 531-541
    • Lanctot, K.L.1    Herrmann, N.2    Van Reekum, R.3    Eryavec, G.4    Naranjo, C.A.5
  • 16
    • 18744394906 scopus 로고    scopus 로고
    • Frontotemporal dementia: Paroxetine as a possible treatment of behavior symptoms: A randomized, controlled, open 14-month study
    • DOI 10.1159/000067021
    • Moretti R., Torre P., Antonello RM, Cazzato G., Bava A. Frontotemporal dementia: paroxetine as a possible treatment of behavior symptoms. A randomized, controlled, open 14-month study. Eur Neurol. 2003 ; 49 (1). 13-19. (Pubitemid 35477963)
    • (2003) European Neurology , vol.49 , Issue.1 , pp. 13-19
    • Moretti, R.1    Torre, P.2    Antonello, R.M.3    Cazzato, G.4    Bava, A.5
  • 18
    • 0842325104 scopus 로고    scopus 로고
    • A randomized, placebo-controlled study of the efficacy and safety of sertraline in the treatment of the behavioral manifestations of Alzheimer's disease in outpatients treated with donepezil
    • DOI 10.1002/gps.998
    • Finkel SI, Mintzer JE, Dysken M., Krishnan KR, Burt T., McRae T. A randomized, placebo-controlled study of the efficacy and safety of sertraline in the treatment of the behavioral manifestations of Alzheimer's disease in outpatients treated with donepezil. Int J Geriatr Psychiatry. 2004 ; 19 (1). 9-18. (Pubitemid 38180687)
    • (2004) International Journal of Geriatric Psychiatry , vol.19 , Issue.1 , pp. 9-18
    • Finkel, S.I.1    Mintzer, J.E.2    Dysken, M.3    Krishnan, K.R.R.4    Burt, T.5    McRae, T.6
  • 19
    • 2442492769 scopus 로고    scopus 로고
    • Paroxetine does not improve symptoms and impairs cognition in frontotemporal dementia: A double-blind randomized controlled trial
    • DOI 10.1007/s00213-003-1686-5
    • Deakin JB, Rahman S., Nestor PJ, Hodges JR, Sahakian BJ Paroxetine does not improve symptoms and impairs cognition in frontotemporal dementia: a double-blind randomized controlled trial. Psychopharmacology (Berl). 2004 ; 172 (4). 400-408. (Pubitemid 38650975)
    • (2004) Psychopharmacology , vol.172 , Issue.4 , pp. 400-408
    • Deakin, J.B.1    Rahman, S.2    Nestor, P.J.3    Hodges, J.R.4    Sahakian, B.J.5
  • 20
    • 38449107464 scopus 로고    scopus 로고
    • A double-blind comparison of citalopram and risperidone for the treatment of behavioral and psychotic symptoms associated with dementia
    • Pollock BG, Mulsant BH, Rosen J., et al. A double-blind comparison of citalopram and risperidone for the treatment of behavioral and psychotic symptoms associated with dementia. Am J Geriatr Psychiatry. 2007 ; 15 (11). 942-952.
    • (2007) Am J Geriatr Psychiatry , vol.15 , Issue.11 , pp. 942-952
    • Pollock, B.G.1    Mulsant, B.H.2    Rosen, J.3
  • 21
    • 67649171309 scopus 로고    scopus 로고
    • Effect of a serotonin reuptake inhibitor on irritability, apathy, and psychotic symptoms in patients with Alzheimer's disease
    • Siddique H., Hynan LS, Weiner MF Effect of a serotonin reuptake inhibitor on irritability, apathy, and psychotic symptoms in patients with Alzheimer's disease. J Clin Psychiatry. 2009 ; 70 (6). 915-918.
    • (2009) J Clin Psychiatry. , vol.70 , Issue.6 , pp. 915-918
    • Siddique, H.1    Hynan, L.S.2    Weiner, M.F.3
  • 22
    • 77949511377 scopus 로고    scopus 로고
    • Sertraline for the treatment of depression in Alzheimer disease: Week-24 outcomes
    • Weintraub D., Rosenberg PB, Drye LT, et al. Sertraline for the treatment of depression in Alzheimer disease: week-24 outcomes. Am J Geriatr Psychiatry. 2010 ; 18 (4). 332-340.
    • (2010) Am J Geriatr Psychiatry. , vol.18 , Issue.4 , pp. 332-340
    • Weintraub, D.1    Rosenberg, P.B.2    Drye, L.T.3
  • 23
    • 78651400870 scopus 로고    scopus 로고
    • Treating neuropsychiatric symptoms in dementia with lewy bodies: A randomized controlled-trial
    • Culo S., Mulsant BH, Rosen J., et al. Treating neuropsychiatric symptoms in dementia with lewy bodies: a randomized controlled-trial. Alzheimer Dis Assoc Disord. 2010 ; 24: 360-364.
    • (2010) Alzheimer Dis Assoc Disord , vol.24 , pp. 360-364
    • Culo, S.1    Mulsant, B.H.2    Rosen, J.3
  • 25
    • 0034649447 scopus 로고    scopus 로고
    • Treatment of agitation in AD: A randomized, placebo-controlled clinical trial
    • Teri L., Logsdon RG, Peskind E., et al. Treatment of agitation in AD: a randomized, placebo-controlled clinical trial. Neurology. 2000 ; 55 (9). 1271-1278.
    • (2000) Neurology , vol.55 , Issue.9 , pp. 1271-1278
    • Teri, L.1    Logsdon, R.G.2    Peskind, E.3
  • 26
    • 0034752166 scopus 로고    scopus 로고
    • Does behavioral improvement with haloperidol or trazodone treatment depend on psychosis or mood symptoms in patients with dementia?
    • DOI 10.1046/j.1532-5415.2001.49256.x
    • Sultzer DL, Gray KF, Gunay I., Wheatley MV, Mahler ME Does behavioral improvement with haloperidol or trazodone treatment depend on psychosis or mood symptoms in patients with dementia ? J Am Geriatr Soc. 2001 ; 49 (10). 1294-1300. (Pubitemid 33015205)
    • (2001) Journal of the American Geriatrics Society , vol.49 , Issue.10 , pp. 1294-1300
    • Sultzer, D.L.1    Gray, K.F.2    Gunay, I.3    Wheatley, M.V.4    Mahler, M.E.5
  • 28
    • 0023881790 scopus 로고
    • Possible neurotransmitter basis of behavioral changes in Alzheimer's disease
    • Palmer AM, Stratmann GC, Procter AW, Bowen DM Possible neurotransmitter basis of behavioral changes in Alzheimer's disease. Ann Neurol. 1988 ; 23 (6). 616-620.
    • (1988) Ann Neurol , vol.23 , Issue.6 , pp. 616-620
    • Palmer, A.M.1    Stratmann, G.C.2    Procter, A.W.3    Bowen, D.M.4
  • 29
    • 0032213211 scopus 로고    scopus 로고
    • Fenfluramine challenge test as a marker of serotonin activity in patients with Alzheimer's dementia and agitation
    • DOI 10.1016/S0006-3223(98)00004-3, PII S0006322398000043
    • Mintzer J., Brawman-Mintzer O., Mirski DF, et al. Fenfluramine challenge test as a marker of serotonin activity in patients with Alzheimer's dementia and agitation. Biol Psychiatry. 1998 ; 44 (9). 918-921. (Pubitemid 28520232)
    • (1998) Biological Psychiatry , vol.44 , Issue.9 , pp. 918-921
    • Mintzer, J.1    Brawman-Mintzer, O.2    Mirski, D.F.3    Unger, R.4    Nietert, P.5    Meeks, A.6    Sampson, R.7
  • 30
    • 0026561451 scopus 로고
    • Biological correlates of clinical heterogeneity in primary dementia
    • Zubenko GS Biological correlates of clinical heterogeneity in primary dementia. Neuropsychopharmacology. 1992 ; 6 (2). 77-93.
    • (1992) Neuropsychopharmacology , vol.6 , Issue.2 , pp. 77-93
    • Zubenko, G.S.1
  • 32
    • 0026322530 scopus 로고
    • Altered serotonergic and cholinergic synaptic markers in Pick's disease
    • Sparks DL, Markesbery WR Altered serotonergic and cholinergic synaptic markers in Pick's disease. Arch Neurol. 1991 ; 48 (8). 796-799.
    • (1991) Arch Neurol , vol.48 , Issue.8 , pp. 796-799
    • Sparks, D.L.1    Markesbery, W.R.2
  • 33
    • 0030947255 scopus 로고    scopus 로고
    • Frontotemporal dementia: Treatment response to serotonin selective reuptake inhibitors
    • Swartz JR, Miller BL, Lesser IM, Darby AL Frontotemporal dementia: treatment response to serotonin selective reuptake inhibitors. J Clin Psychiatry. 1997 ; 58 (5). 212-216. (Pubitemid 27242008)
    • (1997) Journal of Clinical Psychiatry , vol.58 , Issue.5 , pp. 212-216
    • Swartz, J.R.1    Miller, B.L.2    Lesser, I.M.3    Darby, A.L.4
  • 34
    • 12844274439 scopus 로고    scopus 로고
    • Pharmacological treatment of neuropsychiatric symptoms of dementia: A review of the evidence
    • DOI 10.1001/jama.293.5.596
    • Sink KM, Holden KF, Yaffe K. Pharmacological treatment of neuropsychiatric symptoms of dementia: a review of the evidence. JAMA. 2005 ; 293 (5). 596-608. (Pubitemid 40171242)
    • (2005) Journal of the American Medical Association , vol.293 , Issue.5 , pp. 596-608
    • Sink, K.M.1    Holden, K.F.2    Yaffe, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.