Anti-proliferation Effects of Isorhamnetin on Lung Cancer Cells in Vitro and in Vivo

Asian Pacific Journal of Cancer Prevention

Volumn 16, Issue 7, 2015, Pages 3035-3042

  Li, Qiong ^a   Ren, Fu Qiang ^a   Yang, Chun Lei ^a   Zhou, Li Ming ^a   Liu, Yan You ^a   Xiao, Jing ^a   Zhu, Ling ^a   Wang, Zhen Grong ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

A549; Apoptosis; Flavones; Isorhamnetin; Lewis lung carcinoma

Indexed keywords

3-METHYLQUERCETIN; CASPASE 3; CYCLIN D1; CYCLINE; PROTEIN BAX; PROTEIN P53; QUERCETIN;

ANALOGS AND DERIVATIVES; ANIMAL; APOPTOSIS; C57BL MOUSE; CELL PROLIFERATION; DIET THERAPY; DOWN REGULATION; DRUG EFFECTS; HUMAN; LEWIS CARCINOMA; LUNG NEOPLASMS; METABOLISM; MOUSE; TUMOR CELL LINE; UPREGULATION;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, LEWIS LUNG; CASPASE 3; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN D1; DOWN-REGULATION; HUMANS; LUNG NEOPLASMS; MICE; MICE, INBRED C57BL; PROLIFERATING CELL NUCLEAR ANTIGEN; QUERCETIN; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84928647983     PISSN: 15137368     EISSN: None     Source Type: Journal    
DOI: 10.7314/APJCP.2015.16.7.3035     Document Type: Article

References (36)

1. Adachi H, Preston G, Harvat B, Dawson MI, Jetten AM (1998). Inhibition of cell proliferation and induction of apoptosis by the Retinoid AHPN in human lung carcinoma cells. Am J Respir Cell Mol Biol, 18, 323-33.
2. Bhattacharyya A, Mandal D, Lahiry L, Sa G, Das T (2004). Black tea protects immunocytes from tumor-induced apoptosis by changing Bcl-2/Bax ratio. Cancer Lett, 209, 147-54.
3. Chang JY, Chang CY, Kuo CC, et al (2004). Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge (Danshen), with antimitotic activity in multidrug-sensitive and-resistant human tumor cells. Mol Pharmacol, 65, 77-84.
4. Chen JJ, Ai YX, Wang JL (2010). Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis. Nat Chem Biol, 6, 270-2.
5. Das S, Das J, Samadder A, Boujedaini N, Khuda-Bukhsh AR (2012). Exp Biol Med Apigenin-induced apoptosis in A375 and A549 cells through selective action and dysfunction of mitochondria. Exp Biol Med, 237, 1433-48.
6. Gamet-Payrastre L, Li P, Lumeau S, et al (2000). Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells. Cancer Res, 60, 1426-33.
7. Gong WY, Wu JF, Liu BJ, et al (2014). Flavonoid components in Scutellaria baicalensis inhibit nicotine-induced proliferation, metastasis and lung cancer-associated inflammation in vitro. Int J Oncol, 44, 1561-70.
8. Huigsloot M, Tijdens RB, Van de Water B (2003). Inhibition of protein kinase c enhances anticancer agent-induced loss of anchorage-independent growth regardless of protection against apoptosis by Bcl-2. Mol Pharmacol, 64, 965-73.
9. Jacobson MD, Weil M, Raff MC (1997). Programmed cell death in animal development. Cell, 88, 347-54.
10. Kim BR, Hu R, Keum YS, et al (2003). Effects of glutathione on antioxidant response element-mediated gene expression and apoptosis elicited by sulforaphane. Cancer Res, 63, 7520-5.
11. Kuo YF, Su YZ, Tseng YH, et al (2010). Flavokawain B, a novel chalcone from alpinia pricei hayata with potent apoptotic activity: involvement of ROS and GADD153 upstream of mitochondria-dependent apoptosis in HCT116 cells. Free Radical Bio Med, 49, 214-26.
12. Li Y, Wang PZ, Zhang HY (2008). Inhibitive effect of isorhamnetin on epidermal growth factor receptor signal pathway of human gastric carcinoma cells. Chin J Public Health, 24, 1208-9.
13. Ling YH, Jiang JD, Holland JF, Perez-Soler R (2002). Arsenic trioxide produces polymerization of microtubules and mitotic arrest before apoptosis in human tumor cell lines. Mol Pharmacol, 62, 529-38.
14. Liu R, Meng F, Bai H, Liu Y, Liu BW (2007). Inhibitory effect of isorhamnetin and hesperidin on the oxidation of high-density lipoproteins (HDL) induced by Cu2+. J Sichuan Un iv (Med Sci Edi), 38, 961-4.
15. Luo R, Wang JB, Zhao L, et al (2014). Synthesis and biological evaluation of baicalein derivatives as potent antitumor agents. Bioorg Med Chem Lett, 24, 1334-8.
16. Miyata H, DokiY, Yamamoto H, et al (2001). Overexpression of CDC25B Overrides radiation-induced G2-M arrest and results in increased apoptosis in esophageal cancer cells. Cancer Res, 61, 3188-93.
17. Miyoshi N, Uchida K, Osawa T, Nakamura Y (2004). A link between benzyl isothiocyanate-induced cell cycle arrest and apoptosis: involvement of mitogen-activated protein kinases in the Bcl-2 phosphorylation. Cancer Res, 64, 2134-42.
18. Passagne I, Evrard A, Winum JY, et al (2003). Cytotoxicity, DNA damage, and apoptosis induced by new fotemustine analogs on human melanoma cells in relation to o6-methylguanine DNA-methyltransferase expression. J Pharmacol Exp Ther, 307, 816-23.
19. Qin LF, Ng IOL (2002). Induction of apoptosis by cisplatin and its effect on cell cycle-related proteins and cell cycle changes in hepatoma cells. Cancer lett, 75, 27-38.
20. Radhakrishna PG, Srivastava AS, Hassanein TI, Chauhan DP, Carrier E (2004). Induction of apoptosis in human lung cancer cells by curcumin. Cancer Lett, 208, 163-70.
21. Salivesen GS, Dixit VM (1997). Casepases: intracellular signaling by proteolysis. Cell, 91, 443-46.
22. Scatena CD, Stewart ZA, Mays D, et al (1998). Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arrest. J Biol Chem, 273, 30777-84.
23. Singh RP, Agarwal C, Agarwal R (2003). Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes. Carcinogenesis, 24, 555-63.
24. Singh SV, Srivastava SK, Choi S, et al (2005). Sulforaphane-induced cell death in human prostate cancer cells is initiated by reactive oxygen species. J Biol Chem, 280, 19911-24
25. Stoimenov I, Helleday T (2009). PCNA on the crossroad of cancer. Biochem Soc Trans, 37, 605-13.
26. Takagi Y, Du J, Ma XY, Nakashima I, Nagase F (2004). Phorbol 12-myristate 13-acetate protects Jurkat cells from methylglyoxal-induced apoptosis by preventing c-Jun N-terminal kinase-mediated leakage of cytochrome c in an extracellular signal-regulated kinase-dependent manner. Mol Pharmacol, 65, 778-87.
27. Teng D, Cheng JY, Sun J, Zhang Y, Chen WN (2008). The influence of t-PA PAI-1 and vWf that osorhamnetin for ECV304 cells. Chinese Archives of Traditional Chinese Medicine, 26, 1239-40.
28. Uthaisang W, Reutrakul V, Krachangchaeng C, Wilairat P, Fadeel B (2004). VR-3848, a novel peptide derived from Euphobiaceae, induces mitochondria-dependent apoptosis in human leukemia cells. Cancer Lett, 208, 171-8.
29. Vasilevskaya IA, Rakitina TV, O'Dwyer PJ (2004). Quantitative effects on c-Jun N-terminal protein kinase signaling determine synergistic interaction of cisplatin and 17-allylamino-17-demethoxygeldanamycin in colon cancer cell lines. Mol Pharmacol, 65, 235-43.
30. Wang F, Zhang SQ, Dai ZI (1998). Studies on the action of the CM4-ABP antiK562 cancer cells by SCGE. Prog Biochem Biophys, 25, 64-7.
31. Wang ZR, Wang L, Yang HH (2000). Effect of total flavonoids of Hippophae rhamnoides on contractile mechanics and calcium transfer in stretched myocyte. Space Medical Engineering, 13, 6-9.
32. Yang CL, Qu Y, Wang ZR, Tao DC (2004). A inhibitory effect of isorhmnetin on telomerase activity of HeLa cells. J Sichuan Univ, 35, 198-200.
33. Zhong LR, Chen X, Wei KM (2013). Radix tetrastigma hemsleyani flavone induces apoptosis in human lung carcinoma A549 cells by modulating the MAPK pathway. Asian Pac J Cancer Prev. 14, 5983-7
34. Zhu L, Zhou LM, Yang CL, Xiao J, Wang ZR (2004). Study on apoptosis of human A549 cells induced by isorhamntin. Chin J Antibiot, 29, 687-90.
35. Zhu L, Wang ZR, Zhou LM, et al (2005). Effects and mechanisms of Isorhamnetin on lung carcinoma1. Space Med Med Eng, 18, 381-3.
36. Zhu L, Zhou LM, Yang CL, et al (2006). The effect and mechanism of isorhamnetin on lung cancer. Acta Pharmacologica, 27, 69.