Black tea protects immunocytes from tumor-induced apoptosis by changing Bcl-2/Bax ratio

Cancer Letters

Volumn 209, Issue 2, 2004, Pages 147-154

  Bhattacharyya, Arindam ^a   Mandal, Debaprasad ^a   Lahiry, Lakshmishri ^a   Sa, Gaurisankar ^a   Das, Tanya ^a  

^a BOSE INSTITUTE   (India)

Author keywords

Apoptosis; Black tea; EAC, Ehrlich's ascites carcinoma; FACS, Fluorescence activated cell sorter; FITC, Fluorescein isothio cyanate; Immunocyte; Oncoprotein; PI, Propidium iodide; Tumor

Indexed keywords

BLACK TEA EXTRACT; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL PROTECTION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; IMMUNE DEFICIENCY; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN LYMPHOCYTE;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, EHRLICH TUMOR; CELL CYCLE; GENE EXPRESSION REGULATION, NEOPLASTIC; IMMUNOSUPPRESSION; LYMPHOCYTES; MICE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SPLEEN; TEA; TUMOR SUPPRESSOR PROTEIN P53;

CAMELLIA SINENSIS;

EID: 2442708714     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2003.12.025     Document Type: Article

References (34)

1. Chouaib S., Asselin-Paturel C., Mami-Chouaib F., Caignard A., Blay J.Y. The host-tumor immune conflict: from immunosuppression to resistance and destruction. Immunol. Today. 18:1997;493-497
2. Pawelec G., Zeuthen J., Kiessling R. Escape from host-antitumor immunity. Crit. Rev. Oncog. 8:1997;111-141
3. Scott A.M., Cebon J. Clinical promise of tumor immunology. Lancet. 349:1997;SII19-SII22
4. Shu S., Plautz G.E., Krauss J.C., Chang A.E. Tumor immunology. J. Am. Med. Assoc. 278:1997;1972-1981
5. Chen L. Immunological ignorance of silent antigens as an explanation of tumor evasion. Immunol. Today. 19:1998;27-30
6. Anichini A., Fossati G., Parmiani G. Clonal analysis of cytotoxic T lymphocyte response to autologous human melanoma. Int. J. Cancer. 35:1985;683-689
7. Rabinowich H., Banks M., Reichert T., Logan T.F., Kirkwood J.M., Whiteside T.L. Expression and activity of signaling molecules in T lymphocytes obtained from patients with melanoma before and after IL-2 therapy. Clin. Cancer Res. 2:1996;1263-1274
8. Reichert T.E., Rabinowich H., Johnson J.T., Whiteside T.L. Human immune cells in the tumor microenvironment: mechanisms responsible for signaling and functional defects. J. Immunother. 21:1998;295-306
9. Fishman D., Irena B., Kellman-Pressman S., Karas M., Segal S. The role of MHC class I glycoproteins in the regulation of induction of celldeath in immunocytes by malignant melanoma cells. Proc. Natl Acad. Sci. USA. 98:2001;1740-1744
10. Sugiyama K., Ueda H., Ichio Y. Protective effect of juzen-taiho-to against carboplatin-induced toxic side effects in mice. Biol. Pharm. Bull. 18:1995;544-548
11. Weisburger J.H. Mechanisms of action of antioxidants as exemplified in vegetables, tomatoes and tea. Food. Chem. Toxicol. 37:1999;943-948
12. Lu J., Ho C.T., Ghai G., Chen K.Y. Differential effects of theaflavin monogallates on cell growth, apoptosis, and Cox-2 gene expression in cancerous versus normal cells. Cancer. Res. 60:2000;6465-6471
13. Bhattacharyya A., Choudhuri T., Pal S., Chattopadhyay S., Datta G.K., Sa G., Das T. Apoptogenic effects of black tea on Ehrlich's ascites carcinoma cell. Carcinogenesis. 24:2003;75-80
14. Zvetkova E., Wirleitner B., Tram N.T., Schennach H., Fuchs D. Aqueous extracts of Crinum latifolium (L.) and Camellia sinensis show immunomodulatory properties in human peripheral blood mononuclear cells. Int. Immunopharmacol. 12:2001;2143-2150
15. Kapasi A.A., Singhal P.C. Aging splenocyte and thymocyte apoptosis is associated with enhanced expression of p53 Bax, and caspase-3. Mol. Cell. Biol. Res. Commun. 1:1999;78-81
16. Morales-Montor J., Rodriguez-Dorantes M., Mendoza-Rodriguez I., Camacho-Arroyo M.A. Differential expression of the estrogen-regulated proto-oncogenes c-fos, c-jun, and Bcl-2 and of the tumor-suppressor p53 gene in the male mouse chronically infected with Taenia crassiceps cysticerci. Parasitol. Res. 84:1998;616-622
17. Acton D., Jacobs H., Domen J., Berns A. Bcl-2 reduces lymphomagenesis in deltaV-TCR beta transgenic mice. Oncogene. 14:1997;2497-2501
18. Knudson C.M., Tung K.S., Tourtellotte W.G., Brown G.A., Korsmeyer S.J. Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Science. 270:1995;96-101
19. Shanker A., Singh S.M., Sodhi A. Ascitic growth of a spontaneous transplantable T cell lymphoma induces thymic involution. 2. Induction of apoptosis in thymocytes. Tumour. Biol. 21:2000;315-327
20. Ghosh M., Sadhu U., Bhattacharya S., Dutta S., Bhattacharya B., Sanyal U. Evaluation of toxicity of beta-tethymustine, a new anticancer compound, in mice. Cancer Lett. 138:1999;107-114
21. Bhattacharyya A., Sa G., Das T., Siddiqqi M. Black tea-induced cellular survival: evidence for reduced toxicity and enhanced immunity in mice under stress. Int. J. Tea Sci. 2:2003;34-39
22. Nagarkatti N. Tumor-derived Fas ligand induces toxicity in lymphoid organs and plays an important role in successful chemotherapy. Cancer. Immunol. Immunother. 49:2000;46-55
23. Honda H., Inaba T., Suzuki T., Oda H., Ebihara Y., Tsuiji K., et al. Expression of E2A-HLF chimeric protein induced T-cell apoptosis, B-cell maturation arrest, and development of acute lymphoblastic leukemia. Blood. 93:1999;2780-2790
24. Maeda-Yamamoto M., Kawahara H., Matsuda N., Nesumi K., Sano M., Tsuji K., et al. Effects of tea infusions of various varieties or different manufacturing types on inhibition of mouse mast cell activation. Biosci. Biotechnol. Biochem. 62:1998;2277-2279
25. Evan G.I., Vousden K.H. Proliferation, cell cycle and apoptosis in cancer. Nature. 411:2001;342-348
26. Fujikawa K., Hasegawa Y., Matsuzawa S., Fukunaga A., Itoh T., Kondo S. Dose and dose-rate effects of X rays and fission neutrons on lymphocyte apoptosis in p53(+/+) and p53(-/-) mice. J. Radiat. Res. (Tokyo). 41:2000;113-127
27. Korsmeyer S.J., Yin X.M., Oltvai Z.N., Veis-Novack D.J., Linette G.P. Reactive oxygen species and the regulation of cell death by the Bcl-2 gene family. Biochim. Biophys. Acta. 1271:1995;63-66
28. Naka T., Matsumoto T., Narazaki M., Fujimoto M., Morita Y., Ohsawa Y., et al. Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice. Proc. Natl Acad. Sci. USA. 95:1998;15577-15582
29. Kohlmeier L., Weterings K.G., Steck S., Kok F.J. Tea and cancer prevention: an evaluation of the epidemiologic literature. Nutr. Cancer. 27:1997;1-13
30. Lin J., Liang Y. Cancer chemoprevention by tea polyphenols. Proc. Natl Sci. Counc. Repub. China. 24:2000;1-13
31. Balentine D.A. Manufacturing and chemistry of tea. Phenolic compounds in food and their effects on health I: analysis, occurrence, and chemistry. 1992;American Chemical Society, Washington, DC
32. Rafat H., Cillard J., Cillard P. Hydroxyl radical scavenging activity of flavonoids. Phytochemistry. 26:1987;2489-2491
33. Serafini M., Ghiselli A., Ferro-Luzzi A. In vivo antioxidant effect of green and black tea in man. Eur. J. Clin. Nutr. 50:1996;28-32
34. Yang G., Liao J., Kim K., Yurkow E.J., Yang C.S. Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols. Carcinogenesis. 19:1998;611-616