Induction of apoptosis in human lung cancer cells by curcumin

Cancer Letters

Volumn 208, Issue 2, 2004, Pages 163-170

  Pillai, G Radhakrishna ^a   Srivastava, Anand S ^a   Hassanein, Tarek I ^a   Chauhan, Dharam P ^a   Carrier, Ewa ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

bak; bax; bcl 2; bclXL; c myc; Caspase; Curcumin; Lung cancer; p53; PARP

Indexed keywords

CASPASE; CURCUMIN; PROTEIN BAK; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN P53;

APOPTOSIS; ARTICLE; CANCER CELL; CELL GROWTH; CELL LINE; CELL STRAIN; CONTROLLED STUDY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; DRUG EXPOSURE; HUMAN; HUMAN CELL; LUNG CANCER; LUNG NON SMALL CELL CANCER; MOLECULAR BIOLOGY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADENOCARCINOMA; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; CURCUMIN; GENES, MYC; HUMANS; LUNG NEOPLASMS; POLY(ADP-RIBOSE) POLYMERASES; TUMOR SUPPRESSOR PROTEIN P53;

CURCUMA; CURCUMA LONGA;

EID: 2442431538     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2004.01.008     Document Type: Article

References (40)

1. Huang M.T., Lou Y.R., Xie J.G., Ma W., Lu Y.P., Yen P., et al. Effect of dietary curcumin and dibenzoylmethane on formation of 7, 12- dimethylbenz[a]anthracene-induced mammary tumors and lymphomas/leukemias in Sencar mice. Carcinogenesis. 19:1998;1697-1700
2. Samaha H.S., Kelloff G.J., Steele V., Rao C.V., Reddy B.S. Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer chemoprevention and promotion. Cancer Res. 57:1997;1301-1305
3. Verma S.P., Salamone E., Goldin B. Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides. Biochem. Biophys. Res. Commun. 233:1997;692-696
4. Greenblatt M.S., Bennett W.P., Hollstein M., Harris C.C. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res. 54:1994;4855-4878
5. Bhaumik S., Jyothi M.D., Khar A. Differential modulation of nitric oxide production by curcumin in host macrophages and NK cells. Fed. Eur. Biochem. Sci. Lett. 483:2000;78-82
6. Salvesen G.S., Dixit V.M. Caspases: intracellular signaling by proteolysis. Cell. 91:1997;443-446
7. Nagata S. Apoptosis by death factor. Cell. 88:1997;355-365
8. Adams J.M., Cory S. The Bcl-2 protein family: arbiters of cell survival. Science. 281:1998;1322-1326
9. Farrow S.N., Brown R. New members of the Bcl-2 family and their protein partners. Curr. Opin. Genet. Dev. 6:1996;45-49
10. Goel A., Boland C.R., Chauhan D.P. Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells. Cancer Lett. 172:2001;111-118
11. Kaufmann S.H., Desnoyers S., Ottaviano Y., Davidson N.E., Poirier G.G. Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res. 53:1993;3976-3985
12. Los M., Mozoluk M., Ferrari D., Stepczynska A., Stroh C., Renz A., et al. Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling. Mol. Biol. Cell. 13:2002;978-988
13. Gajate C., Santos-Beneit A.M., Macho A., Lazaro M., Hernandez-De Rojas A., Modolell M., et al. Involvement of mitochondria and caspase-3 in ET-18-OCH(3)-induced apoptosis of human leukemic cells. Int. J. Cancer. 86:2000;208-218
14. Oetari S., Sudibyo M., Commandeur J.N., Samhoedi R., Vermeulen N.P. Effects of curcumin on cytochrome P450 and glutathione S-transferase activities in rat liver. Biochem. Pharmacol. 51:1996;39-45
15. Chauhan D.P. Chemotherapeutic potential of curcumin for colorectal cancer. Curr. Pharm. Des. 8:2002;1695-1706
16. Supino R., Perego P., Gatti L., Caserini C., Leonetti C., Colantuono M., et al. A role for c-myc in DNA damage-induced apoptosis in a human TP53-mutant small-cell lung cancer cell line. Eur. J. Cancer. 37:2001;2247-2256
17. Strasser A., Harris A.W., Jacks T., Cory S. DNA damage can induce apoptosis in proliferating lymphoid cells via p53- independent mechanisms inhibitable by Bcl-2. Cell. 79:1994;329-339
18. Ramachandran C., You W. Differential sensitivity of human mammary epithelial and breast carcinoma cell lines to curcumin. Breast Cancer Res. Treat. 54:1999;269-278
19. Hipp M.L., Bauer G. Intercellular induction of apoptosis in transformed cells does not depend on p53. Oncogene. 15:1997;791-797
20. Shao Z.M., Dawson M.I., Li X.S., Rishi A.K., Sheikh M.S., Han Q.X., et al. p53 independent G0/G1 arrest and apoptosis induced by a novel retinoid in human breast cancer cells. Oncogene. 11:1995;493-504
21. Adachi H., Preston G., Harvat B., Dawson M.I., Jetten A.M. Inhibition of cell proliferation and induction of apoptosis by the retinoid AHPN in human lung carcinoma. Am. J. Respir. Cell. Mol. Biol. 18:(3):1998;323-333
22. Miyashita T., Krajewski S., Krajewska M., Wang H.G., Lin H.K., Liebermann D.A., et al. Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene. 9:1994;1799-1805
23. Scott R.J., Krummenacher F., Mary J.L., Weber W., Spycher M., Muller H. Hereditary p53 mutation in a patient with multiple tumors: significance for genetic counseling. Schweiz. Med. Wochenschr. 123:1993;1287-1292
24. Prendergast G.C. Mechanisms of apoptosis by c-Myc. Oncogene. 18:1999;2967-2987
25. Ragimov N., Krauskopf A., Navot N., Rotter V., Oren M., Aloni Y. Wild-type but not mutant p53 can repress transcription initiation in vitro by interfering with the binding of basal transcription factors to the TATA motif. Oncogene. 8:1993;1183-1193
26. Hermeking H., Eick D. Mediation of c-Myc-induced apoptosis by p53. Science. 265:1994;2091-2093
27. Sakamuro D., Eviner V., Elliott K.J., Showe L., White E., Prendergast G.C. c-Myc induces apoptosis in epithelial cells by both p53-dependent and p53-independent mechanisms. Oncogene. 11:1995;2411-2418
28. Wesierska-Gadek J., Bugajska-Schretter A., Cerni C. ADP-ribosylation of p53 tumor suppressor protein: mutant but not wild-type p53 is modified. J. Cell Biochem. 62:1996;90-101
29. Wesierska-Gadek J., Schmid G. Overexpressed poly(ADP-ribose) polymerase delays the release of rat cells from p53-mediated G(1) checkpoint. J. Cell Biochem. 80:2000;85-103
30. Cohen G.M. Caspases: the executioners of apoptosis. Biochem. J. 326. 326:(Pt1):1997;1-16
31. Janicke R.U., Sprengart M.L., Wati M.R., Porter A.G. Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J. Biol. Chem. 273:1998;9357-9360
32. Pandey S., Smith B., Walker P.R., Sikorska M. Caspase-dependent and independent cell death in rat hepatoma 5123tc cells. Apoptosis. 5:2000;265-275
33. Merino R., Grillot D.A., Simonian P.L., Muthukkumar S., Fanslow W.C., Bondada S., Nunez G. Modulation of anti-IgM-induced B cell apoptosis by Bcl-xL and CD40 in WEHI-231 cells. Dissociation from cell cycle arrest and dependence on the avidity of the antibody-IgM receptor interaction. J. Immunol. 155:1995;3830-3838
34. Duyao M.P., Kessler D.J., Spicer D.B., Sonenshein G.E. Binding of NF-KB-like factors to regulatory sequences of the c-myc gene. Curr. Top. Microbiol. Immunol. 166:1990;211-220
35. Susin S.A., Lorenzo H.K., Zamzami N., Marzo I., Brenner C., Larochette N., et al. Mitochondrial release of caspase-2 and -9 during the apoptotic process. J. Exp. Med. 189:1999;381-394
36. Sun X.M., MacFarlane M., Zhuang J., Wolf B.B., Green D.R., Cohen G.M. Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. J. Biol. Chem. 274:1999;5053-5060
37. Zhang H., Heim J., Meyhack B. Novel BNIP1 variants and their interaction with BCL2 family members. Fed. Eur. Biochem. Sci. Lett. 448:1999;23-27
38. Reed J.C. Mechanisms of apoptosis avoidance in cancer. Curr. Opin. Oncol. 11:1999;68-75
39. Cheng E.H., Levine B., Boise L.H., Thompson C.B., Hardwick J.M. Bax-independent inhibition of apoptosis by Bcl-XL. Nature. 379:1996;554-556
40. Pratesi G., Polizzi D., Perego P., Dal Bo L., Zunino F. Bcl-2 phosphorylation in a human breast carcinoma xenograft: a common event in response to effective DNA-damaging drugs. Biochem. Pharmacol. 60:2000;77-82