Cytotoxicity, DNA Damage, and Apoptosis Induced by New Fotemustine Analogs on Human Melanoma Cells in Relation to O6-Methylguanine DNA-Methyltransferase Expression

Journal of Pharmacology and Experimental Therapeutics

Volumn 307, Issue 2, 2003, Pages 816-823

  Passagne, Isabelle ^a   Evrard, Alexandre ^a,b   Winum, Jean Yves ^a   Depeille, Philippe ^a   Cuq, Pierri ^a   Montero, Jean Louis ^a   Cupissol, Didier ^a   Vian, Laurence ^a  

^a UNIV MONTPELLIER   (France)

^b Faculty of Pharmacy   (France)

Author keywords

[No Author keywords available]

Indexed keywords

6 O BENZYLGUANINE; CHLOROETHYLNITROSOUREA DERIVATIVE; DNA FRAGMENT; FOTEMUSTINE; FOTEMUSTINE NITROSOSULFAMIDE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; MONOCLONAL ANTIBODY; SINGLE STRANDED DNA; SULFAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; COMET ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA TRANSFECTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; MELANOMA; MELANOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIDE EFFECT;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CARMUSTINE; DNA DAMAGE; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GUANINE; HUMANS; MELANOMA; NITROSOUREA COMPOUNDS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; ORGANOPHOSPHORUS COMPOUNDS; TUMOR CELLS, CULTURED;

EID: 0142148138     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.051938     Document Type: Article

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