-
1
-
-
0031036307
-
Raf-1/Bcl-2 phosphorylation: A step from microtubule damage to cell death
-
Blagosklonny MV, Giannakakou P, el Deiry WS, Kingston DG, Higgs PI, Neckers L, and Fojo T (1997) Raf-1/Bcl-2 phosphorylation: a step from microtubule damage to cell death. Cancer Res 57:130-135.
-
(1997)
Cancer Res
, vol.57
, pp. 130-135
-
-
Blagosklonny, M.V.1
Giannakakou, P.2
El Deiry, W.S.3
Kingston, D.G.4
Higgs, P.I.5
Neckers, L.6
Fojo, T.7
-
2
-
-
0028972011
-
Taxol induction of P21WAF1 and P53 requires C-Raf-1
-
Blagosklonny MV, Schulte TW, Nguyen P, Mimnaugh EG, Trepel J, and Neckers L (1995) Taxol induction of P21WAF1 and P53 requires C-Raf-1. Cancer Res 55:4623-4626.
-
(1995)
Cancer Res
, vol.55
, pp. 4623-4626
-
-
Blagosklonny, M.V.1
Schulte, T.W.2
Nguyen, P.3
Mimnaugh, E.G.4
Trepel, J.5
Neckers, L.6
-
5
-
-
0031032294
-
Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents
-
Decaudin D, Geley S, Hirsch T, Castedo M, Marchetti P, Macho A, Kofler R, and Kroemer G (1997) Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents. Cancer Res 57:62-67.
-
(1997)
Cancer Res
, vol.57
, pp. 62-67
-
-
Decaudin, D.1
Geley, S.2
Hirsch, T.3
Castedo, M.4
Marchetti, P.5
Macho, A.6
Kofler, R.7
Kroemer, G.8
-
6
-
-
0031026679
-
Cell cycle: Will the real Cdk-activating kinase please stand up
-
Draetta GF (1997) Cell cycle: will the real Cdk-activating kinase please stand up. Curr Biol 7:R50-R52.
-
(1997)
Curr Biol
, vol.7
-
-
Draetta, G.F.1
-
7
-
-
0033052777
-
Mechanisms of action of and resistance to antitubulin agents: Microtubule dynamics, drug transport and cell death
-
Dumontet C and Sikic BI (1999) Mechanisms of action of and resistance to antitubulin agents: microtubule dynamics, drug transport and cell death. J Clin Oncol 17:1061-1070.
-
(1999)
J Clin Oncol
, vol.17
, pp. 1061-1070
-
-
Dumontet, C.1
Sikic, B.I.2
-
8
-
-
0023792382
-
Combined modalities of resistance in etoposide-resistant human KB cell lines
-
Ferguson PJ, Fisher MH, Stephenson J, Li DH, Zhou BS, and Cheng YC (1988) Combined modalities of resistance in etoposide-resistant human KB cell lines. Cancer Res 48:5956-5964.
-
(1988)
Cancer Res
, vol.48
, pp. 5956-5964
-
-
Ferguson, P.J.1
Fisher, M.H.2
Stephenson, J.3
Li, D.H.4
Zhou, B.S.5
Cheng, Y.C.6
-
9
-
-
0021166371
-
A semiautomated microculture method for investigating growth inhibitory effects of cytotoxic compounds on exponentially growing carcinoma cells
-
Finlay GJ, Baguley BC, and Wilson WR (1984) A semiautomated microculture method for investigating growth inhibitory effects of cytotoxic compounds on exponentially growing carcinoma cells. Anal Biochem 139:272-277.
-
(1984)
Anal Biochem
, vol.139
, pp. 272-277
-
-
Finlay, G.J.1
Baguley, B.C.2
Wilson, W.R.3
-
10
-
-
0029954843
-
P-Glycoprotein - A mediator of multidrug resistance in tumour cells
-
Germann UA (1996) P-Glycoprotein-a mediator of multidrug resistance in tumour cells. Eur J Cancer 32A:927-944.
-
(1996)
Eur J Cancer
, vol.32 A
, pp. 927-944
-
-
Germann, U.A.1
-
12
-
-
0029965897
-
Antimitotic natural products and their interactions with tubulin
-
Hamel E (1996) Antimitotic natural products and their interactions with tubulin. Med Res Rev 16:207-231.
-
(1996)
Med Res Rev
, vol.16
, pp. 207-231
-
-
Hamel, E.1
-
13
-
-
0027244234
-
Human Weel maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase
-
Heald R, McLoughlin M, and Mckeon F (1993) Human Weel maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase. Cell 74:463-474.
-
(1993)
Cell
, vol.74
, pp. 463-474
-
-
Heald, R.1
McLoughlin, M.2
Mckeon, F.3
-
14
-
-
0027509501
-
Phosphorylation and activation of human Cdc25-C by Cdc2-cyclin B and its involvement in the self-amplification of MPF at mitosis
-
Hoffmann I, Clarke PR, Marcote MJ, Karsenti E, and Draetta G (1993) Phosphorylation and activation of human Cdc25-C by Cdc2-cyclin B and its involvement in the self-amplification of MPF at mitosis. EMBO (Eur Mol Biol Organ) J 12:53-63.
-
(1993)
EMBO (Eur Mol Biol Organ) J
, vol.12
, pp. 53-63
-
-
Hoffmann, I.1
Clarke, P.R.2
Marcote, M.J.3
Karsenti, E.4
Draetta, G.5
-
15
-
-
0032523959
-
Inhibition of microtubule assembly in tumor cells by 3-bromoacetylamino benzoylurea, a new cancericidal compound
-
Jiang JD, Wang Y, Roboz J, Strauchen J, Holland JF, and Bekesi JG (1998) Inhibition of microtubule assembly in tumor cells by 3-bromoacetylamino benzoylurea, a new cancericidal compound. Cancer Res 58:2126-2133.
-
(1998)
Cancer Res
, vol.58
, pp. 2126-2133
-
-
Jiang, J.D.1
Wang, Y.2
Roboz, J.3
Strauchen, J.4
Holland, J.F.5
Bekesi, J.G.6
-
16
-
-
0031872051
-
Tubulin as a target for anticancer drugs: Agents which interact with the mitotic spindle
-
Jordan A, Hadfield JA, Lawrence NJ, and McGown AT (1998) Tubulin as a target for anticancer drugs: agents which interact with the mitotic spindle. Med Res Rev 18:259-296.
-
(1998)
Med Res Rev
, vol.18
, pp. 259-296
-
-
Jordan, A.1
Hadfield, J.A.2
Lawrence, N.J.3
McGown, A.T.4
-
17
-
-
0030931827
-
Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes
-
Kavallaris M, Kuo DY, Burkhart CA, Regl DL, Norris MD, Haber M, and Horwitz SB (1997) Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes. J Clin Investig 100:1282-1293.
-
(1997)
J Clin Investig
, vol.100
, pp. 1282-1293
-
-
Kavallaris, M.1
Kuo, D.Y.2
Burkhart, C.A.3
Regl, D.L.4
Norris, M.D.5
Haber, M.6
Horwitz, S.B.7
-
18
-
-
0035422780
-
Multiple microtubule alterations are associated with Vinca alkaloid resistance in human leukemia cells
-
Kavallaris M, Tait AS, Walsh BJ, He L, Horwitz SB, Norris MD, and Haber M (2001) Multiple microtubule alterations are associated with Vinca alkaloid resistance in human leukemia cells. Cancer Res 61:5803-5809.
-
(2001)
Cancer Res
, vol.61
, pp. 5803-5809
-
-
Kavallaris, M.1
Tait, A.S.2
Walsh, B.J.3
He, L.4
Horwitz, S.B.5
Norris, M.D.6
Haber, M.7
-
19
-
-
0028956550
-
Regulators of cell death
-
Korsmeyer SJ (1995) Regulators of cell death. Trends Genet 11:101-105.
-
(1995)
Trends Genet
, vol.11
, pp. 101-105
-
-
Korsmeyer, S.J.1
-
20
-
-
0025980359
-
The Cdc25 protein controls tyrosine dephosphorylation of the Cdc2 protein in a cell-free system
-
Kumagai A and Dunphy WG (1991) The Cdc25 protein controls tyrosine dephosphorylation of the Cdc2 protein in a cell-free system. Cell 64:903-914.
-
(1991)
Cell
, vol.64
, pp. 903-914
-
-
Kumagai, A.1
Dunphy, W.G.2
-
21
-
-
0029895941
-
Synthesis of 5-(3-hydroxypropyl)-7-methoxy-2-(3′-methoxy-4′ -hydroxyphenyl)-3-benzo[b]furancarbaldehyde, a novel adenosine A1 receptor ligand from the root of Salvia miltiorrhizae
-
Kuo Y-H and Wu C-H (1996) Synthesis of 5-(3-hydroxypropyl)-7-methoxy-2-(3′-methoxy-4′-hydroxyphenyl) -3-benzo[b]furancarbaldehyde, a novel adenosine A1 receptor ligand from the root of Salvia miltiorrhizae. J Nat Prod (Lloydia) 59:625-628.
-
(1996)
J Nat Prod (Lloydia)
, vol.59
, pp. 625-628
-
-
Kuo, Y.-H.1
Wu, C.-H.2
-
22
-
-
0034997538
-
Two new fatty diterpenoids from Salvia miltiorrhizae
-
Lin H-C, Ding H-Y, and Chang W-L (2001) Two new fatty diterpenoids from Salvia miltiorrhizae. J Nat Prod (Lloydia) 64:648-650.
-
(2001)
J Nat Prod (Lloydia)
, vol.64
, pp. 648-650
-
-
Lin, H.-C.1
Ding, H.-Y.2
Chang, W.-L.3
-
23
-
-
0026601262
-
Protective action of seven natural phenolic compounds against peroxidative damage to biomembranes
-
Liu GT, Zhang TM, Wang BE, and Wang YW (1992) Protective action of seven natural phenolic compounds against peroxidative damage to biomembranes. Biochem Pharmacol 43:147-152.
-
(1992)
Biochem Pharmacol
, vol.43
, pp. 147-152
-
-
Liu, G.T.1
Zhang, T.M.2
Wang, B.E.3
Wang, Y.W.4
-
24
-
-
0026752669
-
Identification of novel antimitotic agents acting at the tubulin level by computer-assisted evaluation of differential cytotoxicity data
-
Paull KD, Lin CM, Malspeis L, and Hamel E (1992) Identification of novel antimitotic agents acting at the tubulin level by computer-assisted evaluation of differential cytotoxicity data. Cancer Res 52:3892-3900.
-
(1992)
Cancer Res
, vol.52
, pp. 3892-3900
-
-
Paull, K.D.1
Lin, C.M.2
Malspeis, L.3
Hamel, E.4
-
25
-
-
0032783884
-
Multidrug resistance in human tumors-molecular diagnosis and clinical significance
-
Ramachandran C and Melnick SJ (1999) Multidrug resistance in human tumors-molecular diagnosis and clinical significance. Mol Diagn 4:81-94.
-
(1999)
Mol Diagn
, vol.4
, pp. 81-94
-
-
Ramachandran, C.1
Melnick, S.J.2
-
26
-
-
0029973041
-
Increase of beta(III)- and beta(IVa)-tubulin isotopes in human prostate carcinoma cells as a result of estramustine resistance
-
Ranganathan S, Dexter DW, Benetatos CA, Chapman AE, Tew KD, and Hudes GR (1996) Increase of beta(III)- and beta(IVa)-tubulin isotopes in human prostate carcinoma cells as a result of estramustine resistance. Cancer Res 56:2584-2589.
-
(1996)
Cancer Res
, vol.56
, pp. 2584-2589
-
-
Ranganathan, S.1
Dexter, D.W.2
Benetatos, C.A.3
Chapman, A.E.4
Tew, K.D.5
Hudes, G.R.6
-
28
-
-
0026345003
-
The clinical pharmacology and use of antimicrotubule agents in cancer chemotherapeutics
-
Rowinsky EK and Donehower RC (1991) The clinical pharmacology and use of antimicrotubule agents in cancer chemotherapeutics. Pharmacol Ther 52:35-84.
-
(1991)
Pharmacol Ther
, vol.52
, pp. 35-84
-
-
Rowinsky, E.K.1
Donehower, R.C.2
-
29
-
-
0029767016
-
Structural basis of cyclin-dependent kinase activation by phosphorylation
-
Russo AA, Jeffrey PD, and Pavletich NP (1996) Structural basis of cyclin-dependent kinase activation by phosphorylation. Nat Struct Biol 3:696-700.
-
(1996)
Nat Struct Biol
, vol.3
, pp. 696-700
-
-
Russo, A.A.1
Jeffrey, P.D.2
Pavletich, N.P.3
-
31
-
-
0032514914
-
Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and taxol-induced growth arrest
-
Scatena CD, Stewart ZA, Mays D, Tang LJ, Keefer CJ, Leach SD, and Pietenpol JA (1998) Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and taxol-induced growth arrest. J Biol Chem 273:30777-30784.
-
(1998)
J Biol Chem
, vol.273
, pp. 30777-30784
-
-
Scatena, C.D.1
Stewart, Z.A.2
Mays, D.3
Tang, L.J.4
Keefer, C.J.5
Leach, S.D.6
Pietenpol, J.A.7
-
32
-
-
0000297058
-
Taxol stabilizes microtubules in mouse fibroblast cells
-
Schiff PB and Horwitz SB (1980) Taxol stabilizes microtubules in mouse fibroblast cells. Proc Natl Acad Sci USA 77:1561-1565.
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 1561-1565
-
-
Schiff, P.B.1
Horwitz, S.B.2
-
33
-
-
0025922083
-
Dephosphorylation and activation of a P34cdc2/cyclin B complex in vitro by human CDC25 protein
-
Strausfeld U, Labbe JC, Fesquet D, Cavadore JC, Picard A, Sadhu K, Russell P, and Doree M (1991) Dephosphorylation and activation of a P34cdc2/cyclin B complex in vitro by human CDC25 protein. Nature (Lond) 351:242-245.
-
(1991)
Nature (Lond)
, vol.351
, pp. 242-245
-
-
Strausfeld, U.1
Labbe, J.C.2
Fesquet, D.3
Cavadore, J.C.4
Picard, A.5
Sadhu, K.6
Russell, P.7
Doree, M.8
-
34
-
-
0035879010
-
A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors
-
Tahir SK, Han EK, Credo B, Jae HS, Pietenpol JA, Scatena CD, Wu-Wong JR, Frost D, Sham H, Rosenberg SH, et al. (2001) A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors. Cancer Res 61:5480-5485.
-
(2001)
Cancer Res
, vol.61
, pp. 5480-5485
-
-
Tahir, S.K.1
Han, E.K.2
Credo, B.3
Jae, H.S.4
Pietenpol, J.A.5
Scatena, C.D.6
Wu-Wong, J.R.7
Frost, D.8
Sham, H.9
Rosenberg, S.H.10
-
35
-
-
0028047288
-
Cloning of CDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope
-
Westendorf JM, Rao PN, and Gerace L (1994) Cloning of CDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope. Proc Natl Acad Sci USA 91:714-718.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 714-718
-
-
Westendorf, J.M.1
Rao, P.N.2
Gerace, L.3
-
36
-
-
0035146128
-
The spindle: A dynamic assembly of microtubules and motors
-
Wittmann T, Hyman A, and Desai A (2001) The spindle: a dynamic assembly of microtubules and motors. Nat Cell Biol 3:E28-E34.
-
(2001)
Nat Cell Biol
, vol.3
-
-
Wittmann, T.1
Hyman, A.2
Desai, A.3
-
37
-
-
0026309074
-
Cytotoxic activities of tanshinones against human carcinoma cell lines
-
Wu WL, Chang WL, and Chen CF (1991) Cytotoxic activities of tanshinones against human carcinoma cell lines. Am J Chin Med 19:207-216.
-
(1991)
Am J Chin Med
, vol.19
, pp. 207-216
-
-
Wu, W.L.1
Chang, W.L.2
Chen, C.F.3
-
38
-
-
0024502823
-
Possible active components of tan-shen (Salvia miltiorrhiza) for protection of the myocardium against ischemia-induced derangements
-
Yagi A, Fujimoto K, Tanonaka K, Hirai K, and Takeo S (1989) Possible active components of tan-shen (Salvia miltiorrhiza) for protection of the myocardium against ischemia-induced derangements. Planta Med 55:51-54.
-
(1989)
Planta Med
, vol.55
, pp. 51-54
-
-
Yagi, A.1
Fujimoto, K.2
Tanonaka, K.3
Hirai, K.4
Takeo, S.5
-
39
-
-
0025876482
-
1 receptor ligand isolated from Salvia miltiorrhiza bunge (Danshen)
-
1 receptor ligand isolated from Salvia miltiorrhiza bunge (Danshen). Tetrahedron Lett 32: 2061-2064.
-
(1991)
Tetrahedron Lett
, vol.32
, pp. 2061-2064
-
-
Yang, Z.1
Hon, P.M.2
Chui, K.Y.3
Xu, Z.L.4
Chang, H.M.5
Lee, C.M.6
Cui, Y.X.7
Wong, H.N.C.8
Poon, C.D.9
Fung, B.M.10
-
40
-
-
0027049774
-
Compounds from Danshen. Part 7. Regioselective introduction of carbon-3 substituents to 5-alkyl-7-methoxy-2-phenylbenzo[b]furans: Synthesis of a novel adenosine Al receptor ligand and its derivatives
-
Yang Z, Liu HB, Lee CM, Chang HM, and Wong HNC (1992) Compounds From Danshen. Part 7. Regioselective introduction of carbon-3 substituents to 5-alkyl-7-methoxy-2-phenylbenzo[b]furans: synthesis of a novel adenosine Al receptor ligand and its derivatives. J Org Chem 57:7248-7257.
-
(1992)
J Org Chem
, vol.57
, pp. 7248-7257
-
-
Yang, Z.1
Liu, H.B.2
Lee, C.M.3
Chang, H.M.4
Wong, H.N.C.5
|