Alteration of structure and function of ATP synthase and cytochrome c oxidase by lack of Fo-a and Cox3 subunits caused by mitochondrial DNA 9205delTA mutation

Biochemical Journal

Volumn 466, Issue 3, 2015, Pages 601-611

  Hejzlarová, Kateřina ^a   Kaplanová, Vilma ^a   Nůsková, Hana ^a   Kovářová, Nikola ^a   Ješina, Pavel ^a   Drahota, Zdeněk ^a   Mráček, Tomáš ^a   Seneca, Sara ^b   Houštěk, Josef ^a  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

^b UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

Author keywords

ATP synthase; Cytochrome c oxidase; Mitochondrial diseases; MtDNA MT ATP6 mutation; Oxidative phosphorylation; Threshold effect

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; CYTOCHROME C OXIDASE; DIGITONIN; HYDROLASE; MITOCHONDRIAL DNA; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; MT-ATP6 PROTEIN, HUMAN; PROTEIN SUBUNIT;

ARTICLE; BIOSYNTHESIS; CELL FREE SYSTEM; CELL ISOLATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME STRUCTURE; GENE MUTATION; HETEROPLASMY; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOLECULAR WEIGHT; OXYGEN CONSUMPTION; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION MAPPING; WESTERN BLOTTING; WHOLE CELL; CELL LINE; CHEMISTRY; DEFICIENCY; GENE DELETION; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY; PROTEIN SUBUNIT;

CELL LINE; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT COMPLEX IV; GENE DELETION; HUMANS; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; MUTATION; PROTEIN SUBUNITS;

EID: 84928639745     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20141462     Document Type: Article

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